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Schizotypal personality

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https://www.readbyqxmd.com/read/29174334/is-there-a-common-vulnerability-in-cannabis-phenomenology-and-schizotypy-the-role-of-the-n170-erp
#1
Gabriel A Brooks, Colleen A Brenner
Cannabis use is a known risk factor for the development of psychosis, although the precise nature of this relationship is unclear. The phenomenological experiences associated with cannabis use vary dramatically, and for some resemble certain features of psychosis. We hypothesized that individuals who report particularly unusual experiences associated with cannabis use would demonstrate similar electrophysiological patterns to those who score high on schizotypal personality traits. The Cannabis Experiences Questionnaire (CEQ) and the Schizotypal Personality Questionnaire (SPQ) were used to measure these experiences and traits...
November 21, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29171491/-the-efficacy-and-tolerability-of-pericyazine-in-the-treatment-of-patients-with-schizotypal-disorder-organic-personality-disorders-and-pathocharacterological-changes-within-personality-disorders
#2
D S Danilov
AIM: To assess the efficacy and tolerability of pericyazine in the treatment of patients with mental disorders manifesting with psychopathic-like symptoms and correction of pathocharacterological disorders in patients with personality disorders during the short-term admission to the hospital or the long-term outpatient treatment. MATERIAL AND METHODS: Sixty-three patients with schizotypal personality disorder and organic personality disorder with psychopathic-like symptoms and pathocharacterological changes within the diagnosis of dissocial personality disorder and borderline personality disorder were examined...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29159135/the-influence-of-schizotypal-traits-on-attention-under-high-perceptual-load
#3
Hanne Stotesbury, Sebastian B Gaigg, Saim Kirhan, Corinna Haenschel
Schizophrenia Spectrum Disorders (SSD) are known to be characterised by abnormalities in attentional processes, but there are inconsistencies in the literature that remain unresolved. This article considers whether perceptual resource limitations play a role in moderating attentional abnormalities in SSD. According to perceptual load theory, perceptual resource limitations can lead to attenuated or superior performance on dual-task paradigms depending on whether participants are required to process, or attempt to ignore, secondary stimuli...
March 2018: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/29131991/enhanced-mental-imagery-and-intact-perceptual-organization-in-schizotypal-personality-disorder
#4
Rebeka Maróthi, Szabolcs Kéri
According to a widely held view, psychotic disorders such as schizophrenia are characterized by a vague boundary between the perception of the external world and the inner imagery of persons, objects, and events. In this study, we addressed the perception-imagery debate in schizotypal personality disorder (SPD). Thirty individuals with SPD and 30 matched healthy subjects completed a lateral masking task. Participants were asked to detect a low-contrast Gabor patch flanked by two collinear Gabor masks. In the perceptual task, the masks were physically present, whereas in the imagery task, participants only imagined the masks...
November 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29113776/brief-assessment-of-schizotypal-traits-a-multinational-study
#5
Eduardo Fonseca-Pedrero, Javier Ortuño-Sierra, Beatriz Lucas-Molina, Martin Debbané, Raymond C K Chan, David C Cicero, Lisa C Zhang, Colleen Brenner, Emma Barkus, Richard J Linscott, Thomas Kwapil, Neus Barrantes-Vidal, Alex Cohen, Adrian Raine, Michael T Compton, Erin B Tone, Julie Suhr, Julio Bobes, Axit Fumero, Stella Giakoumaki, Ioannis Tsaousis, Antonio Preti, Michael Chmielewski, Julien Laloyaux, Anwar Mechri, Mohamed Aymen Lahmar, Viviana Wuthrich, Frank Larøi, Johanna C Badcock, Assen Jablensky, David Barron, Viren Swami, Ulrich S Tran, Martin Voracek
The Schizotypal Personality Questionnaire-Brief (SPQ-B) was developed with the aim of examining variations in healthy trait schizotypy, as well as latent vulnerability to psychotic-spectrum disorders. No previous study has studied the cross-cultural validity of the SPQ-B in a large cross-national sample. The main goal of the present study was to analyze the reliability and the internal structure of SPQ-B scores in a multinational sample of 28,426 participants recruited from 14 countries. The mean age was 22...
November 4, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29095898/brain-gray-matter-structural-network-in-myotonic-dystrophy-type-1
#6
Atsuhiko Sugiyama, Daichi Sone, Noriko Sato, Yukio Kimura, Miho Ota, Norihide Maikusa, Tomoko Maekawa, Mikako Enokizono, Madoka Mori-Yoshimura, Yasushi Ohya, Satoshi Kuwabara, Hiroshi Matsuda
This study aimed to investigate abnormalities in structural covariance network constructed from gray matter volume in myotonic dystrophy type 1 (DM1) patients by using graph theoretical analysis for further clarification of the underlying mechanisms of central nervous system involvement. Twenty-eight DM1 patients (4 childhood onset, 10 juvenile onset, 14 adult onset), excluding three cases from 31 consecutive patients who underwent magnetic resonance imaging in a certain period, and 28 age- and sex- matched healthy control subjects were included in this study...
2017: PloS One
https://www.readbyqxmd.com/read/29065890/the-mediating-effects-of-childhood-neglect-on-the-association-between-schizotypal-and-autistic-personality-traits-and-depression-in-a-non-clinical-sample
#7
Jianbo Liu, Jingbo Gong, Guanghui Nie, Yuqiong He, Bo Xiao, Yanmei Shen, Xuerong Luo
BACKGROUND: Autistic personality traits (APT) and schizotypal personality traits (SPT) are associated with depression. However, mediating factors within these relationships have not yet been explored. Thus, the focus of the current study was to examine the effects of childhood neglect on the relationship between APT/SPT and depression. METHODS: This cross-sectional study was conducted on first-year students (N = 2469) at Hunan University of Chinese Medicine and Hengyang Normal College (Changsha, China)...
October 25, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29036523/stress-dependent-association-between-polygenic-risk-for-schizophrenia-and-schizotypal-traits-in-young-army-recruits
#8
Alex Hatzimanolis, Dimitrios Avramopoulos, Dan E Arking, Anna Moes, Pallav Bhatnagar, Todd Lencz, Anil K Malhotra, Stella G Giakoumaki, Panos Roussos, Nikolaos Smyrnis, Panos Bitsios, Nicholas C Stefanis
Schizotypal personality traits may increase proneness to psychosis and likely index familial vulnerability to schizophrenia (SZ), implying shared genetic determinants with SZ. Here, we sought to investigate the contribution of common genetic risk variation for SZ on self-reported schizotypy in 2 ethnically homogeneous cohorts of healthy young males during compulsory military service, enrolled in the Athens Study of Proneness and Incidence of Schizophrenia (ASPIS, N = 875) and the Learning on Genetics of Schizophrenia Spectrum study (LOGOS, N = 690)...
June 13, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29024192/association-of-schizotypy-with-striatocortical-functional-connectivity-and-its-asymmetry-in-healthy-adults
#9
Yi Wang, Ulrich Ettinger, Thomas Meindl, Raymond C K Chan
Altered striatocortical functional connectivity has been suggested to be a trait marker of schizophrenia spectrum disorders, including schizotypal personality. In the present study, we examined the association between schizotypal personality traits and striatocortical functional connectivity in a sample of healthy adults. The German version of the Schizotypal Personality Questionnaire was obtained from N = 111 participants recruited from the general public. Resting-state functional magnetic resonance imaging scans were acquired at 3T...
October 11, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28956087/a-compromise-solution-between-overlapping-and-overlooking-dsm-personality-disorders-in-chinese-psychiatric-practice
#10
SuoYu Zhu, TianHong Zhang, ChengQing Yang, YanYan Wei, LiHua Xu, JunJie Wang, Annabelle Chow, XiaoHua Liu, KaiDa Jiang, ZePing Xiao, Hui Zhou, JiJun Wang
OBJECTIVE: This study aimed to examine the overlaps between the Diagnostic and Statistical Manual-5 (DSM-5) Personality Disorders (PDs) in a high-risk clinical population and to explore a transitional model for implementing DSM-5 PDs. METHOD: A sample population of 982 outpatients with at least one diagnosed PD was selected from 3,075 outpatients of the Shanghai Mental Health Center. The diagnostic process comprised of a personality diagnostic questionnaire and a structured clinical interview...
September 27, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28955212/classifying-schizotypy-using-an-audiovisual-emotion-perception-test-and-scalp-electroencephalography
#11
Ji Woon Jeong, Tariku W Wendimagegn, Eunhee Chang, Yeseul Chun, Joon Hyuk Park, Hyoung Joong Kim, Hyun Taek Kim
Schizotypy refers to the personality trait of experiencing "psychotic" symptoms and can be regarded as a predisposition of schizophrenia-spectrum psychopathology (Raine, 1991). Cumulative evidence has revealed that individuals with schizotypy, as well as schizophrenia patients, have emotional processing deficits. In the present study, we investigated multimodal emotion perception in schizotypy and implemented the machine learning technique to find out whether a schizotypy group (ST) is distinguishable from a control group (NC), using electroencephalogram (EEG) signals...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28953820/study-on-the-prescribing-patterns-of-antipsychotic-medication-in-a-rural-england-community-mental-health-team
#12
Madhavan Seshadri, Ahmed Elsemary, Madhusudan Deepak Thalitaya, Lawrence Chikodzore, Priya Nagalingam
INTRODUCTION: Providing comprehensive services for about 400 patients in the South Herefordshire area, the community mental health team manages cases of varying severity and complexity, ranging from Schizophrenia, to neuroses and disorders of adult personality. Antipsychotic medication remains a mainstay of treatment and management for patients under the team case load; hence a need exists for a detailed look into the prescription patterns of such medications. AIM: The aim of this study was to look into the prescribing patterns of antipsychotics for a sample of 50 patients in the South Herefordshire community team during the year of 2016 (from Jan 2016 to Dec 2016), as well as investigate whether these antipsychotics were licensed to be used for the corresponding diagnoses of these patients...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28950739/are-periodontal-outcomes-affected-by-personality-patterns-a-18-month-follow-up-study
#13
Carlo Bertoldi, Marco Venuta, Gianpaolo Guaraldi, Michele Lalla, Stefania Guaitolini, Luigi Generali, Daniele Monzani, Pierpaolo Cortellini, Davide Zaffe
OBJECTIVES: This research aims to study the relationship between personality traits and periodontal clinical outcomes by taking into account the level of anxiety and depression, periodontal health and oral hygiene behaviour of patients affected with gingivitis or moderate periodontitis requiring periodontal therapy. MATERIAL AND METHODS: The periodontal data of 40 systemically healthy patients affected by gingivitis or moderate periodontitis were collected at baseline and 18 months later...
September 26, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28946869/understanding-others-a-pilot-investigation-of-cognitive-and-affective-facets-of-social-cognition-in-patients-with-22q11-2-deletion-syndrome-22q11ds
#14
D Badoud, M Schneider, S Menghetti, B Glaser, M Debbané, S Eliez
BACKGROUND: Although significant impairments in the affective and cognitive facets of social cognition have been highlighted in patients with 22q11.2 deletion syndrome (22q11DS) in previous studies, these domains have never been investigated simultaneously within the same group of participants. Furthermore, despite theoretical evidence, associations between these two processes and schizotypal symptoms or social difficulties in this population have been scarcely examined. METHODS: Twenty-nine participants with 22q11DS and 27 typically developing controls (N = 5 siblings; N = 22 unrelated controls) aged between 11 and 21 years participated in the study...
September 25, 2017: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/28939392/self-and-other-directed-forms-of-violence-and-their-relationship-with-lifetime-dsm-5-psychiatric-disorders-results-from-the-national-epidemiologic-survey-on-alcohol-related-conditions-iii-nesarc-iii
#15
Thomas C Harford, Chiung M Chen, Bradley T Kerridge, Bridget F Grant
A combined history of violence toward self and others has been reported in clinical and incarcerated populations. Psychiatric disorders have been implicated as risk factors. This study examines the lifetime prevalence of this combined violence in the general population and its associations with DSM-5 psychiatric disorders in comparison with other- and self-directed violence. Data from the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) were analyzed, including 36,309 U.S. adults ages 18 and older...
September 13, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28936192/the-intricate-relationship-between-psychotic-like-experiences-and-associated-subclinical-symptoms-in-healthy-individuals
#16
Lui Unterrassner, Thomas A Wyss, Diana Wotruba, Helene Haker, Wulf Rössler
The interplay between subclinical psychotic, negative, and affective symptoms has gained increased attention regarding the etiology of psychosis spectrum and other mental disorders. Importantly, research has tended to not differentiate between different subtypes of psychotic-like experiences (PLE) although they may not have the same significance for mental health. In order to gain information on the subclinical interplay between specific PLE and other symptoms as well as the significance of PLE for mental health, we investigated their specific associations in 206 healthy individuals (20-60 years, 73 females) using correlational and linear regression analyses...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28931092/the-genome-wide-associated-candidate-gene-znf804a-and-psychosis-proneness-evidence-of-sex-modulated-association
#17
Marta de Castro-Catala, Aurea Mora-Solano, Thomas R Kwapil, Paula Cristóbal-Narváez, Tamara Sheinbaum, Anna Racioppi, Neus Barrantes-Vidal, Araceli Rosa
BACKGROUND: The Zinc finger protein 804A (ZNF804A) is a promising candidate gene for schizophrenia and the broader psychosis phenotype that emerged from genome-wide association studies. It is related to neurodevelopment and associated to severe symptoms of schizophrenia and alterations in brain structure, as well as positive schizotypal personality traits in non-clinical samples. Moreover, a female-specific association has been observed between ZNF804A and schizophrenia. AIM: The present study examined the association of two ZNF804A polymorphisms (rs1344706 and rs7597593) with the positive dimension of schizotypy and psychotic-like experiences in a sample of 808 non-clinical subjects...
2017: PloS One
https://www.readbyqxmd.com/read/28899612/the-schizotypal-personality-questionnaire-brief-lacks-measurement-invariance-across-three-countries
#18
Shujuan Liu, David Mellor, Mathew Ling, José L Saiz, Eugenia V Vinet, Xiaoyan Xu, Solomon Renati, Linda K Byrne
The Schizotypal Personality Questionnaire-Brief (SPQ-B) is a commonly-used tool for measuring schizotypal personality traits and due to its wide application, its cross-cultural validity is of interest. Previous studies suggest that the SPQ-B either has a three- or four-factor structure, but the majority of studies have been conducted in Western contexts and little is known about the psychometric properties of the scale in other populations. In this study factorial invariance testing across three cultural contexts-Australia, China and Chile was conducted...
December 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28884713/-mental-disorders-in-patients-with-breast-cancer-a-differentiated-approach-to-the-study-of-nozogeny
#19
O V Shushpanova
AIM: To study mental disorders in patients with breast cancer (BC) at different stages of the disease taking into account premorbid characteristics and psychosomatic correlations in their development. MATERIAL AND METHODS: The study included 82 patients with histologically confirmed BC. The first group consisted of 30 patients (mean age 49.7±11.1 years) with the first established diagnosis of BC and mental disorders caused by somatic disease (ICD-10 F40-F48, stress-related neurotic and somatoform disorders)...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28864974/oxytocin-and-schizophrenia-spectrum-disorders
#20
Ulrich Ettinger, René Hurlemann, Raymond C K Chan
In this chapter, we present an overview of studies of oxytocin (OXT) in schizophrenia and the schizophrenia spectrum. We first outline the current state of pharmacological treatment of the symptoms of schizophrenia and point to unmet clinical needs. These relate particularly to the debilitating negative symptoms and social cognitive deficits that are frequently observed in patients suffering from schizophrenia. We argue that new treatments are needed to alleviate these impairments. As OXT has been proposed and investigated as a putative treatment, we will then summarise evidence from studies in patients with schizophrenia that have investigated the effects of OXT at several levels, i...
September 2, 2017: Current Topics in Behavioral Neurosciences
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