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Schizotypal personality

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https://www.readbyqxmd.com/read/29454512/frontal-and-temporal-cortical-volume-white-matter-tract-integrity-and-hemispheric-asymmetry-in-schizotypal-personality-disorder
#1
Chi C Chan, Philip R Szeszko, Edmund Wong, Cheuk Y Tang, Caitlin Kelliher, Justin D Penner, M Mercedes Perez-Rodriguez, Daniel R Rosell, Margaret McClure, Panos Roussos, Antonia S New, Larry J Siever, Erin A Hazlett
Abnormalities in temporal and frontal cortical volume, white matter tract integrity, and hemispheric asymmetry have been implicated in schizophrenia-spectrum disorders. Schizotypal personality disorder can provide insight into vulnerability and protective factors in these disorders without the confounds associated with chronic psychosis. However, multimodal imaging and asymmetry studies in SPD are sparse. Thirty-seven individuals with SPD and 29 healthy controls (HC) received clinical interviews and 3T magnetic resonance T1-weighted and diffusion tensor imaging scans...
February 14, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29448863/mental-health-literacy-sub-clinical-personality-disorders-and-job-fit
#2
Adrian Furnham, Kelly Petropoulou
BACKGROUND: This study looked at lay theories of how people with sub-clinical personality disorders experience the world of work. AIMS: The aim was to investigate the paradox that subclinical and clinical personality disorders are seen as beneficial for success, rather than a handicap in certain jobs. METHODS: In all, 230 participants read 14 vignettes derived from Oldham and Morris's book describing DSMIII personality disorders for a popular audience...
February 15, 2018: Journal of Mental Health
https://www.readbyqxmd.com/read/29414034/stress-induced-cortisol-release-and-schizotypy
#3
Emma E Walter, Francesca Fernandez, Mollie Snelling, Emma Barkus
Cortisol is involved in preparing the body's response for stress. However, in those at risk for mental health problems, abnormal cortisol release following stress has been reported. In particular, we are yet to fully understand how stress leads to an exacerbation of symptoms and progression of risk in those who express psychosis proneness or schizotypy. Using the Trier Social Stress Test, we examined the effect of experimentally induced psychosocial stress on cortisol release in otherwise healthy individuals with schizotypal traits...
January 30, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29410313/motor-dysfunction-as-research-domain-in-the-period-preceding-manifest-schizophrenia-a-systematic-review
#4
REVIEW
Dusan Hirjak, Andreas Meyer-Lindenberg, Katharina M Kubera, Philipp A Thomann, Robert C Wolf
Schizophrenia is a severe behavioral syndrome of neurodevelopmental nature marked by primary or genuine motor abnormalities (GMA), which refer to spontaneous and medication-independent motor phenomena. Since motor dysfunction thus might be a consequence of events occurring during early childhood and adolescence, GMA can be detected in the period preceding manifest schizophrenia. However, the question whether motor system dysfunction might be a promising motor intermediate phenotype for schizophrenia remains unanswered...
February 2, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29395871/clinically-significant-personality-traits-in-individuals-at-high-risk-of-developing-psychosis
#5
Julia Sevilla-Llewellyn-Jones, Gustavo Camino, Debra A Russo, Michelle Painter, Angel L Montejo, Susana Ochoa, Peter B Jones, Jesus Perez
It is still unclear to what extent personality may influence the development of psychosis. We aimed to explore significant personality traits in individuals at high-risk (HR) for psychosis. Personalities of forty HR individuals and a matched sample of 40 healthy volunteers (HVs) were evaluated with the Millon Multiaxial Inventory (MCMI-III). They were also assessed with the Positive and Negative Symptoms Scale (PANSS), Beck Depression and Anxiety Inventories (BDI-II and BAI), Global Assessment of Functioning (GAF) and Mini-International Neuropsychiatric Interview (MINI 6...
March 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29373967/personality-dimensions-emerging-during-adolescence-and-young-adulthood-are-underpinned-by-a-single-latent-trait-indexing-impairment-in-social-functioning
#6
Ela Polek, Peter B Jones, Pasco Fearon, Jeannette Brodbeck, Michael Moutoussis, Nspn Consortium, Ray Dolan, Peter Fonagy, Edward T Bullmore, Ian M Goodyer
BACKGROUND: Personality with stable behavioural traits emerges in the adolescent and young adult years. Models of putatively distinct, but correlated, personality traits have been developed to describe behavioural styles including schizotypal, narcissistic, callous-unemotional, negative emotionality, antisocial and impulsivity traits. These traits have influenced the classification of their related personality disorders. We tested if a bifactor model fits the data better than correlated-factor and orthogonal-factor models and subsequently validated the obtained factors with mental health measures and treatment history...
January 26, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29373752/identity-disturbance-feelings-of-emptiness-and-the-boundaries-of-the-schizophrenia-spectrum
#7
Maja Zandersen, Josef Parnas
Historical and current research on borderline personality disorder reveal certain affinities with schizophrenia spectrum psychopathology. This is also the case for the borderline criteria of "identity disturbance" and "feelings of emptiness," which reflect symptomatology frequently found in schizophrenia and schizotypal personality disorder. Unfortunately, the diagnostic manuals offer limited insight into the nature of these criteria, including possible deviations and similarities with schizophrenia spectrum symptomatology...
January 24, 2018: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29329058/association-of-comorbid-personality-disorders-with-clinical-characteristics-and-outcome-in-a-randomized-controlled-trial-comparing-two-psychotherapies-for-early-onset-persistent-depressive-disorder
#8
Nele Erkens, Elisabeth Schramm, Levente Kriston, Martin Hautzinger, Martin Härter, Ulrich Schweiger, Jan Philipp Klein
BACKGROUND: Persistent depressive disorder (PDD) is associated with high rates of comorbid personality disorders (PD). The association of comorbid PD and clinical characteristics has not been systematically studied in PDD. Results regarding effects on treatment outcome are heterogeneous. METHODS: We analyzed the association of comorbid personality disorders with clinical characteristics and outcome in a randomized controlled trial comparing the disorder-specific Cognitive Behavioral Analysis System of Psychotherapy (CBASP) with nonspecific supportive psychotherapy (SP) in patients with early-onset PDD...
January 4, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29323511/representing-schizotypal-thinking-with-dimensional-traits-a-case-for-the-five-factor-schizotypal-inventory
#9
Erin L Moorman, Douglas B Samuel
Building on support for the five-factor model (FFM) of personality disorder, the Five Factor Schizotypal Inventory (FFSI) was developed to assess maladaptive traits relevant to schizotypal personality disorder. While the development of the FFSI supports a continuity between schizotypal thinking and perception (STAP) and the FFM domain of Openness to Experience, other studies show inconsistent findings concerning the strength of this relationship. The current study evaluates these relationships by investigating specific components of a short-form of the FFSI (e...
January 2018: Psychological Assessment
https://www.readbyqxmd.com/read/29174334/is-there-a-common-vulnerability-in-cannabis-phenomenology-and-schizotypy-the-role-of-the-n170-erp
#10
Gabriel A Brooks, Colleen A Brenner
Cannabis use is a known risk factor for the development of psychosis, although the precise nature of this relationship is unclear. The phenomenological experiences associated with cannabis use vary dramatically, and for some resemble certain features of psychosis. We hypothesized that individuals who report particularly unusual experiences associated with cannabis use would demonstrate similar electrophysiological patterns to those who score high on schizotypal personality traits. The Cannabis Experiences Questionnaire (CEQ) and the Schizotypal Personality Questionnaire (SPQ) were used to measure these experiences and traits...
November 21, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29171491/-the-efficacy-and-tolerability-of-pericyazine-in-the-treatment-of-patients-with-schizotypal-disorder-organic-personality-disorders-and-pathocharacterological-changes-within-personality-disorders
#11
D S Danilov
AIM: To assess the efficacy and tolerability of pericyazine in the treatment of patients with mental disorders manifesting with psychopathic-like symptoms and correction of pathocharacterological disorders in patients with personality disorders during the short-term admission to the hospital or the long-term outpatient treatment. MATERIAL AND METHODS: Sixty-three patients with schizotypal personality disorder and organic personality disorder with psychopathic-like symptoms and pathocharacterological changes within the diagnosis of dissocial personality disorder and borderline personality disorder were examined...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29159135/the-influence-of-schizotypal-traits-on-attention-under-high-perceptual-load
#12
Hanne Stotesbury, Sebastian B Gaigg, Saim Kirhan, Corinna Haenschel
Schizophrenia Spectrum Disorders (SSD) are known to be characterised by abnormalities in attentional processes, but there are inconsistencies in the literature that remain unresolved. This article considers whether perceptual resource limitations play a role in moderating attentional abnormalities in SSD. According to perceptual load theory, perceptual resource limitations can lead to attenuated or superior performance on dual-task paradigms depending on whether participants are required to process, or attempt to ignore, secondary stimuli...
March 2018: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/29131991/enhanced-mental-imagery-and-intact-perceptual-organization-in-schizotypal-personality-disorder
#13
Rebeka Maróthi, Szabolcs Kéri
According to a widely held view, psychotic disorders such as schizophrenia are characterized by a vague boundary between the perception of the external world and the inner imagery of persons, objects, and events. In this study, we addressed the perception-imagery debate in schizotypal personality disorder (SPD). Thirty individuals with SPD and 30 matched healthy subjects completed a lateral masking task. Participants were asked to detect a low-contrast Gabor patch flanked by two collinear Gabor masks. In the perceptual task, the masks were physically present, whereas in the imagery task, participants only imagined the masks...
November 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29113776/brief-assessment-of-schizotypal-traits-a-multinational-study
#14
Eduardo Fonseca-Pedrero, Javier Ortuño-Sierra, Beatriz Lucas-Molina, Martin Debbané, Raymond C K Chan, David C Cicero, Lisa C Zhang, Colleen Brenner, Emma Barkus, Richard J Linscott, Thomas Kwapil, Neus Barrantes-Vidal, Alex Cohen, Adrian Raine, Michael T Compton, Erin B Tone, Julie Suhr, Julio Bobes, Axit Fumero, Stella Giakoumaki, Ioannis Tsaousis, Antonio Preti, Michael Chmielewski, Julien Laloyaux, Anwar Mechri, Mohamed Aymen Lahmar, Viviana Wuthrich, Frank Larøi, Johanna C Badcock, Assen Jablensky, David Barron, Viren Swami, Ulrich S Tran, Martin Voracek
The Schizotypal Personality Questionnaire-Brief (SPQ-B) was developed with the aim of examining variations in healthy trait schizotypy, as well as latent vulnerability to psychotic-spectrum disorders. No previous study has studied the cross-cultural validity of the SPQ-B in a large cross-national sample. The main goal of the present study was to analyze the reliability and the internal structure of SPQ-B scores in a multinational sample of 28,426 participants recruited from 14 countries. The mean age was 22...
November 4, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29095898/brain-gray-matter-structural-network-in-myotonic-dystrophy-type-1
#15
Atsuhiko Sugiyama, Daichi Sone, Noriko Sato, Yukio Kimura, Miho Ota, Norihide Maikusa, Tomoko Maekawa, Mikako Enokizono, Madoka Mori-Yoshimura, Yasushi Ohya, Satoshi Kuwabara, Hiroshi Matsuda
This study aimed to investigate abnormalities in structural covariance network constructed from gray matter volume in myotonic dystrophy type 1 (DM1) patients by using graph theoretical analysis for further clarification of the underlying mechanisms of central nervous system involvement. Twenty-eight DM1 patients (4 childhood onset, 10 juvenile onset, 14 adult onset), excluding three cases from 31 consecutive patients who underwent magnetic resonance imaging in a certain period, and 28 age- and sex- matched healthy control subjects were included in this study...
2017: PloS One
https://www.readbyqxmd.com/read/29065890/the-mediating-effects-of-childhood-neglect-on-the-association-between-schizotypal-and-autistic-personality-traits-and-depression-in-a-non-clinical-sample
#16
Jianbo Liu, Jingbo Gong, Guanghui Nie, Yuqiong He, Bo Xiao, Yanmei Shen, Xuerong Luo
BACKGROUND: Autistic personality traits (APT) and schizotypal personality traits (SPT) are associated with depression. However, mediating factors within these relationships have not yet been explored. Thus, the focus of the current study was to examine the effects of childhood neglect on the relationship between APT/SPT and depression. METHODS: This cross-sectional study was conducted on first-year students (N = 2469) at Hunan University of Chinese Medicine and Hengyang Normal College (Changsha, China)...
October 25, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29036523/stress-dependent-association-between-polygenic-risk-for-schizophrenia-and-schizotypal-traits-in-young-army-recruits
#17
Alex Hatzimanolis, Dimitrios Avramopoulos, Dan E Arking, Anna Moes, Pallav Bhatnagar, Todd Lencz, Anil K Malhotra, Stella G Giakoumaki, Panos Roussos, Nikolaos Smyrnis, Panos Bitsios, Nicholas C Stefanis
Schizotypal personality traits may increase proneness to psychosis and likely index familial vulnerability to schizophrenia (SZ), implying shared genetic determinants with SZ. Here, we sought to investigate the contribution of common genetic risk variation for SZ on self-reported schizotypy in 2 ethnically homogeneous cohorts of healthy young males during compulsory military service, enrolled in the Athens Study of Proneness and Incidence of Schizophrenia (ASPIS, N = 875) and the Learning on Genetics of Schizophrenia Spectrum study (LOGOS, N = 690)...
June 13, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/29024192/association-of-schizotypy-with-striatocortical-functional-connectivity-and-its-asymmetry-in-healthy-adults
#18
Yi Wang, Ulrich Ettinger, Thomas Meindl, Raymond C K Chan
Altered striatocortical functional connectivity has been suggested to be a trait marker of schizophrenia spectrum disorders, including schizotypal personality. In the present study, we examined the association between schizotypal personality traits and striatocortical functional connectivity in a sample of healthy adults. The German version of the Schizotypal Personality Questionnaire was obtained from N = 111 participants recruited from the general public. Resting-state functional magnetic resonance imaging scans were acquired at 3T...
October 11, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28956087/a-compromise-solution-between-overlapping-and-overlooking-dsm-personality-disorders-in-chinese-psychiatric-practice
#19
SuoYu Zhu, TianHong Zhang, ChengQing Yang, YanYan Wei, LiHua Xu, JunJie Wang, Annabelle Chow, XiaoHua Liu, KaiDa Jiang, ZePing Xiao, Hui Zhou, JiJun Wang
OBJECTIVE: This study aimed to examine the overlaps between the Diagnostic and Statistical Manual-5 (DSM-5) Personality Disorders (PDs) in a high-risk clinical population and to explore a transitional model for implementing DSM-5 PDs. METHOD: A sample population of 982 outpatients with at least one diagnosed PD was selected from 3,075 outpatients of the Shanghai Mental Health Center. The diagnostic process comprised of a personality diagnostic questionnaire and a structured clinical interview...
September 27, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28955212/classifying-schizotypy-using-an-audiovisual-emotion-perception-test-and-scalp-electroencephalography
#20
Ji Woon Jeong, Tariku W Wendimagegn, Eunhee Chang, Yeseul Chun, Joon Hyuk Park, Hyoung Joong Kim, Hyun Taek Kim
Schizotypy refers to the personality trait of experiencing "psychotic" symptoms and can be regarded as a predisposition of schizophrenia-spectrum psychopathology (Raine, 1991). Cumulative evidence has revealed that individuals with schizotypy, as well as schizophrenia patients, have emotional processing deficits. In the present study, we investigated multimodal emotion perception in schizotypy and implemented the machine learning technique to find out whether a schizotypy group (ST) is distinguishable from a control group (NC), using electroencephalogram (EEG) signals...
2017: Frontiers in Human Neuroscience
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