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Aristide Merola, Alberto Romagnolo, Laura Rizzi, Mario Giorgio Rizzone, Maurizio Zibetti, Michele Lanotte, George Mandybur, Andrew P Duker, Alberto J Espay, Leonardo Lopiano
To determine the clinical and demographic correlates of persistent, remitting, and new-onset impulse control behaviors (ICBs) before and after subthalamic deep brain stimulation (STN-DBS) in Parkinson's disease (PD). We compared the pre- and post-surgical prevalence of ICBs, classified as impulse control disorders (ICD), dopamine dysregulation syndrome (DDS), and punding in 150 consecutive PD STN-DBS-treated patients and determined the association with motor, cognitive, neuropsychological, and neuropsychiatric endpoints...
October 19, 2016: Journal of Neurology
Nikolai Albert, Louise Birkedal Glenthøj, Marianne Melau, Heidi Jensen, Carsten Hjorthøj, Merete Nordentoft
BACKGROUND: Previous studies report that 20% to 30% of those initially diagnosed with schizotypal disorder go on to develop a psychotic disorder (predominantly schizophrenia). Schizotypal disorder share some traits of those used to identify patients at ultra-high risk for psychosis. METHOD: As part of a randomized clinical trial testing the effect of prolonged specialized early intervention, we recruited 83 participants diagnosed with a schizotypal disorder. Participants were recruited 18 months into their two-year treatment program, and follow-up interviews were conducted three and a half year later...
October 16, 2016: Schizophrenia Research
Vladan Starcevic, Vlasios Brakoulias
PURPOSE OF REVIEW: This article aims to examine the relationships between obsessive-compulsive disorder (OCD) and personality disturbance, with a particular focus on the diagnostic, aetiological and treatment implications of these relationships. RECENT FINDINGS: Personality disorders are common in OCD. They interact in various ways and in accordance with a number of the proposed models. The relationship between OCD and obsessive-compulsive personality disorder is the most important, but it can be conceptualised in different ways and may vary from one person to another...
October 15, 2016: Current Opinion in Psychiatry
Eduardo Fonseca-Pedrero, Alex Cohen, Javier Ortuño-Sierra, Alicia Pérez de Álbeniz, José Muñiz
The main goal of the present study was to test the measurement equivalence of the Schizotypal Personality Questionnaire - Brief Revised (SPQ-BR) scores in a large sample of Spanish and American non-clinical young adults. The sample was made up of 5,625 young adults (M = 19.65 years; SD = 2.53; 38.5% males). Study of the internal structure, using confirmatory factor analysis (CFA), revealed that SPQ-BR items were grouped in a theoretical internal structure of nine first-order factors. Moreover, three or four second-order factor and bifactor models showed adequate goodness-of-fit indices...
October 17, 2016: Journal of Personality Disorders
Cristina Crego, Thomas A Widiger
The purpose of the present study was to compare the cognitive and perceptual aberration scales from the Five-Factor Schizotypal Inventory (FFSI; Edmundson, Lynam, Miller, Gore, & Widiger, 2011) and the Personality Inventory for DSM-5 (Krueger, Derringer, Markon, Watson, & Skodol, 2012), as well as to address more generally the validity of the FFSI as a measure of both schizotypal personality traits and the FFM. Two independent samples were obtained, including 259 college students (55 of whom were preselected with elevated scores on a measure of schizotypal personality disorder [STPD]) and 346 adult MTurk participants (43% of whom had been or were currently in mental health treatment)...
October 17, 2016: Journal of Personality Disorders
Ana L Fernandez-Cruz, Ola Mohamed Ali, Gifty Asare, Morgan S Whyte, Ishan Walpola, Julia Segal, J Bruno Debruille
Some personal drives correspond to extraordinary social roles. Given that behavioral strategies associated with such drives may conflict with those associated with ordinary roles, they could cause behavioral disorganization. To test whether they do so independent of the factors responsible for full-blown schizotypy and schizophrenia, these drives were assessed in the general population. Two hundred and nine healthy volunteers were individually presented with hundreds of names of social roles in experimental psychology conditions...
2016: NPJ Schizophrenia
Ahmad Abu-Akel, Jennifer Clark, Amy Perry, Stephen J Wood, Liz Forty, Nick Craddock, Ian Jones, Katherine Gordon-Smith, Lisa Jones
OBJECTIVE: To determine the expression of autistic and positive schizotypal traits in a large sample of adults with bipolar I disorder (BD I), and the effect of co-occurring autistic and positive schizotypal traits on global functioning in BD I. METHOD: Autistic and positive schizotypal traits were self-assessed in 797 individuals with BD-I recruited by the Bipolar Disorder Research Network. Differences in global functioning (rated using the Global Assessment Scale) during lifetime worst depressive and manic episodes (GASD and GASM respectively) were calculated in groups with high/low autistic and positive schizotypal traits...
October 3, 2016: Journal of Affective Disorders
(no author information available yet)
Reports an error in "Psychosis-Predictive Value of Self-Reported Schizotypy in a Clinical High-Risk Sample" by Rahel Flückiger, Stephan Ruhrmann, Martin Debbané, Chantal Michel, Daniela Hubl, Benno G. Schimmelmann, Joachim Klosterkötter and Frauke Schultze-Lutter (Journal of Abnormal Psychology, Advanced Online Publication, Sep 1, 2016, np). In the article, there was an error in the Author Note. The affiliation of Daniela Hubl was incorrectly listed as "University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern...
October 2016: Journal of Abnormal Psychology
Patrick Raynal, Nelly Goutaudier, Victoria Nidetch, Henri Chabrol
Few typological studies address schizotypy in young adults. Schizotypal traits were assessed on 466 college students using the Schizotypal Personality Questionnaire-Brief (SPQ-B). Other measures evaluated personality traits previously associated with schizotypy (borderline, obsessionnal, and autistic traits), psychopathological symptoms (suicidal ideations, depressive and obsessive-compulsive symptoms) and psychosocial functioning. A factor analysis was first performed on SPQ-B results, leading to four factors: negative schizotypy, positive schizotypy, social anxiety, and reference ideas...
September 26, 2016: Psychiatry Research
Yi Wang, Yi Deng, Zhi Li, Xu Li, Chen-Yuan Zhang, Zhen Jin, Ming-Xia Fan, Michael T Compton, Eric F C Cheung, Kelvin O Lim, Raymond C K Chan
Minor physical anomalies (MPAs) are subtle signs of fetal developmental abnormalities that have been considered to be among the most replicated risk markers for schizophrenia-spectrum disorders. However, quantitative approaches are needed to measure craniofacial MPAs. The present study adopted an imaging-based quantitative approach to examine craniofacial MPAs across the spectrum of schizophrenia and affective disorders, to address their sensitivity and specificity. We sampled 31 patients with schizophrenia, 30 of their unaffected relatives, and 30 individuals with schizotypal personality traits, as well as 37 non-schizotypal controls...
October 8, 2016: PsyCh Journal
Estêvão Scotti-Muzzi, Osvaldo Luis Saide
The presence of obsessive-compulsive symptoms (OCS) and obsessive-compulsive disorders (OCD) in schizophrenia is frequent, and a new clinical entity has been proposed for those who show the dual diagnosis: the schizo-obsessive disorder. This review scrutinizes the literature across the main academic databases, and provides an update on different aspects of schizo-obsessive spectrum disorders, which include schizophrenia, schizotypal personality disorder (SPD) with OCD, OCD with poor insight, schizophrenia with OCS, and schizophrenia with OCD (schizo-obsessive disorder)...
September 27, 2016: CNS Spectrums
Raymond C K Chan, Zhuo-Ya Yang, Zhi Li, Dong-Jie Xie, Diane C Gooding
Social anhedonia, the reduced capacity for social and interpersonal pleasure, often accompanies several forms of psychopathology. The goal of the present study was to validate the Chinese translation of the Anticipatory and Consummatory Interpersonal Pleasure Scale (ACIPS), a promising new tool for the assessment of individual differences in social pleasure. The Chinese versions of the ACIPS, the Temporal Experience of Pleasure Scale (TEPS), and the Schizotypal Personality Questionnaire (SPQ) were administered to 389 nonclinical adults...
September 25, 2016: PsyCh Journal
A Ferchiou, L Todorov, M Lajnef, G Baudin, B Pignon, J-R Richard, M Leboyer, A Szöke, F Schürhoff
INTRODUCTION: The main objective of the study was to explore the factorial structure of the French version of the Schizotypal Personality Questionnaire-Brief (SPQ-B) in a Likert format, in a representative sample of the general population. In addition, differences in the dimensional scores of schizotypy according to gender and age were analyzed. As the study in the general population of schizotypal traits and its determinants has been recently proposed as a way toward the understanding of aetiology and pathophysiology of schizophrenia, consistent self-report tools are crucial to measure psychometric schizotypy...
September 16, 2016: L'Encéphale
E I Rasskazova, M A Omel'chenko, A O Rumyantsev, V G Kaleda
AIM: To determine characteristics of cognitive insight and its relationship with the severity and dynamics of symptoms in patients with ultra-high risk for schizophrenia during treatment. MATERIAL AND METHODS: The study included 76 young patients with subpsychotic symptoms corresponding to criteria of ultra-high risk for psychosis and 55 healthy subjects. Patients were examined using psychopathological analysis and a battery of psychological tests. RESULTS AND CONCLUSION: Cognitive insight, although not linked to objective indicators of ultra-high risk for schizophrenia, predicts a decline in both total score of SOPS, and in the Positive symptoms subscale during the treatment of patients with personality disorders...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
R Landin-Romero, P J McKenna, A Romaguera, E Álvarez-Moya, S Sarró, C Aguirre, C Sarri, A Compte, C Bosque, R Salvador, E Pomarol-Clotet
BACKGROUND: A key finding underlying the continuum of psychosis concept is the presence of psychotic-like experiences (PLEs) in healthy subjects. However, it remains uncertain to what extent these experiences are related to the genetic risk for schizophrenia and how far they actually resemble attenuated forms of psychotic symptoms. METHODS: Forty-nine adults with no history of mental illness in first-degree relatives and 59 siblings of patients with schizophrenia were rated on the psychosis section of the Computerized Diagnostic Interview Schedule IV (C DIS-IV) and the Rust Inventory of Schizotypal Cognitions (RISC)...
September 12, 2016: Schizophrenia Research
Chrysoula Zouraraki, Ioannis Tsaousis, Penny Karamaouna, Leda Karagiannopoulou, Panos Roussos, Panos Bitsios, Stella G Giakoumaki
BACKGROUND: Increased schizotypal traits are observed in a percentage of the general population and in the schizophrenia-spectrum and have been associated with impairments in working memory. In this study we examined the effects of four schizotypal dimensions [Negative (NegS), Paranoid (ParS), Cognitive-Perceptual (CPS), Disorganized (DiS)] on executive working memory (EWM), as mediated by set-shifting, planning and control inhibition. We also examined whether these associations are moderated by family-history of psychosis...
August 21, 2016: Comprehensive Psychiatry
Irie D Schimanski, Kelly L Mouat, Bronwyn L Billinghurst, Richard J Linscott
We tested artifactual and theory-based accounts of the relationship between schizophrenia liability and suicidality. At baseline, 387 adolescents (12 to 17years) completed measures of schizotypy, hopelessness, and depressed affect. After two years, schizotypal and non-schizotypal subsamples (n=16 and 31, respectively) self-reported passive suicidal ideation, active ideation, and serious ideation and action. Taxonic schizotypy predicted passive ideation (OR=8.15, 95% CI 1.34, 49.60) even when controlling for depressed affect...
September 6, 2016: Schizophrenia Research
Eleni Zarogianni, Amos J Storkey, Eve C Johnstone, David G C Owens, Stephen M Lawrie
To date, there are no reliable markers for predicting onset of schizophrenia in individuals at high risk (HR). Substantial promise is, however, shown by a variety of pattern classification approaches to neuroimaging data. Here, we examined the predictive accuracy of support vector machine (SVM) in later diagnosing schizophrenia, at a single-subject level, using a cohort of HR individuals drawn from multiply affected families and a combination of neuroanatomical, schizotypal and neurocognitive variables. Baseline structural magnetic resonance imaging (MRI), schizotypal and neurocognitive data from 17 HR subjects, who subsequently developed schizophrenia and a matched group of 17 HR subjects who did not make the transition, yet had psychotic symptoms, were included in the analysis...
September 6, 2016: Schizophrenia Research
Zhenjie Wang, Ning Li, Chao Guo, Lei Zhang, Gong Chen, Xiaoying Zheng
The world will be facing huge population aged 65 and older, accounting for 13% of the total population in the future. Significant disabilities rates reflect an accumulation of health risks. Psychiatry disability is one of the most significant disabilities, because it manifests in cognitive, affective, and behavior disorders that limit one's daily life and restrict their participations. Very few studies have explored the 20 years associations between demographic factors and psychiatry disability among older people in China...
September 2016: Medicine (Baltimore)
Kyung-Ok Lim, Tae Young Lee, Minah Kim, Myong-Wuk Chon, Je-Yeon Yun, Sung Nyun Kim, Jun Soo Kwon
AIM: A clinical high risk (CHR) for psychosis is regarded as the state of being at risk of developing psychosis. However, the rate of transition to psychosis among CHR subjects has been declining over time. We aimed to investigate the effects of the possible causes of the declining transition rate. METHODS: A total of 129 CHR subjects were divided into two groups according to the date of enrollment: the 2005-2009 group and the 2009-2013 group. Baseline demographic and clinical characteristics, including medication prescription, were compared...
September 7, 2016: Early Intervention in Psychiatry
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