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https://www.readbyqxmd.com/read/29652779/is-the-current-management-of-patients-presenting-with-spinal-trauma-to-district-general-hospitals-fit-for-purpose-our-experience-of-delivering-a-spinal-service-using-an-electronic-referral-platform-in-a-large-district-general-teaching-hospital-without-onsite
#1
Daniel S Hill, Hans Marynissen
STUDY DESIGN: A retrospective cross-sectional analysis. OBJECTIVE: To describe the provision of a spinal service using an electronic platform to direct management from an external spinal unit, and quantify time taken to obtain definitive management plans whilst under prescribed spinal immobilization. SUMMARY OF BACKGROUND DATA: Most attending district general hospitals following spinal trauma will have stable injuries and normal neurology, with only a small proportion requiring urgent transfer to a specialist centre...
April 12, 2018: Spine
https://www.readbyqxmd.com/read/29629239/sub-airy-confocal-adaptive-optics-scanning-ophthalmoscopy
#2
Nripun Sredar, Oladipo E Fagbemi, Alfredo Dubra
Purpose: To demonstrate the viability of improving transverse image resolution in reflectance scanning adaptive optics ophthalmoscopy using sub-Airy disk confocal detection. Methods: The foveal cone mosaic was imaged in five human subjects free of known eye disease using two custom adaptive optics scanning light ophthalmoscopes (AOSLOs) in reflectance with 7.75 and 4.30 mm pupil diameters. Confocal pinholes of 0.5, 0.6, 0.8, and 1.0 Airy disk diameters (ADDs) were used in a retinal conjugate plane before the light detector...
April 2018: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/29628809/cytokine-involvement-in-biological-inflammation-related-to-degenerative-disorders-of-the-intervertebral-disk-a-narrative-review
#3
REVIEW
Christopher M De Geer
Objective: The purpose of this narrative literature review is to discuss the literature regarding the potential role that cytokines play in degenerative disk disease. Methods: The inclusion criteria were studies that used inflammatory mediators in advancing disk disease processes. Research studies were limited to the last 3 decades that had free full-text available online in English. Exclusion criteria were review articles and articles pertaining to temporomandibular joints and other joints of the body other than the intervertebral disk...
March 2018: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/29620587/mucolipidosis-type-ii-affecting-1-fetus-and-placental-disk-of-a-dichorionic-diamnionic-twin-gestation-a-case-report-and-review-of-the-literature
#4
David B Chapel, Bonnie Choy, Peter Pytel, Aliya N Husain, Ricardo R Lastra
Mucolipidosis type II, also known as I-cell disease, is an autosomal recessive inborn error of metabolism, resulting from loss-of-function mutations in GNPTAB. Affected infants exhibit multiple physical anomalies and developmental delay, and death from disease follows in early childhood. Here we present an instructive case of mucolipidosis type II affecting 1 fetus and placental disk in a dichorionic-diamnionic twin pregnancy delivered at 36-wk gestation. The second twin and placental disk showed no abnormality...
April 3, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29619122/cervicothoracic-lordosis-can-influence-outcome-after-posterior-cervical-spine-surgery
#5
Albert Vincent Berthier Brasil, Pablo Ramon Fruett da Costa, Antonio Delacy Martini Vial, Gabriel da Costa Barcellos, Eduardo Balverdu Zauk, Paulo Valdeci Worm, Marcelo Paglioli Ferreira, Nelson Pires Ferreira
Background: Previous studies on the correlation between cervical sagittal balance with improvement in quality of life showed significant results only for parameters of the anterior translation of the cervical spine (such as C2-C7 SVA). Objective: We test whether a new parameter, cervicothoracic lordosis , can predict clinical success in this type of surgery. Methods: The focused group involved patients who underwent surgical treatment of cervical degenerative disk disease by the posterior approach, due to myelopathy, radiculopathy or a combination of both...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29596611/comparison-of-frankliniella-fusca-and-frankliniella-occidentalis-thysanoptera-thripidae-as-vectors-for-a-peanut-strain-of-tomato-spotted-wilt-orthotospovirus
#6
Steven P Arthurs, Kevin M Heinz, Forrest L Mitchell
Tomato spotted wilt orthotospovirus (TSWV) is a major disease in peanut, Arachis hypogaea L., across peanut producing regions of the United States and elsewhere. Two thrips, Frankliniella fusca Hinds and Frankliniella occidentalis Pergande (Thysanoptera: Thripidae), are considered important vectors of TSWV in peanut in the Southeast. We compared the efficiency of acquisition (by larvae) and transmission (adults) of both thrips species for TSWV (Texas peanut-strain) to leaf disks of peanut (Florunner), as well as to Impatiens walleriana Hook...
March 27, 2018: Environmental Entomology
https://www.readbyqxmd.com/read/29595747/postoperative-infection-in-patients-undergoing-posterior-lumbosacral-spinal-surgery-a-pictorial-guide-for-diagnosis-and-early-treatment
#7
Shih-Hao Chen, Wen-Jer Chen, Meng-Huang Wu, Jen-Chung Liao, Chen-Ju Fu
Surgical site infections after posterior spinal surgery may lead to spondylodiscitis, pseudarthrosis, correction loss, adverse neurological sequelae, sepsis, and poor outcomes if not treated immediately. Infection rates vary depending on the type and extent of operative procedures, use of instrumentation, and patients' risk factors. Image evaluation is crucial for early diagnosis and should be complementary to clinical routes, laboratory survey, and treatment timing. Magnetic resonance imaging detects early inflammatory infiltration into the vertebrae and soft tissues, including hyperemic changes of edematous marrow, vertebral endplate, and abscess or phlegmon accumulation around the intervertebral disk, epidural, and paravertebral spaces...
March 27, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29594059/severe-inflammatory-ophthalmopathy-in-a-euthyroid-patient-during-nivolumab-treatment
#8
Pauline Campredon, Philippe Imbert, Céline Mouly, Solange Grunenwald, Julien Mazières, Philippe Caron
Introduction: Nivolumab is a promising treatment in patients with advanced malignancies. Among immune-related adverse events, autoimmune thyroid disorders are frequently reported. Patient: A 61-year-old male patient had no history of familial or personal thyroid disease. In 2012, this patient, a heavy smoker, presented with non-small-cell lung cancer that was treated with radiotherapy and chemotherapy. In 2015, the cancer progressed with cervical compressive symptoms, and the patient was treated with nivolumab...
March 2018: European Thyroid Journal
https://www.readbyqxmd.com/read/29593901/frequent-benign-nontraumatic-noninflammatory-causes-of-low-back-pain-in-adolescents-mri-findings
#9
Aikaterini Solomou, Pantelis Kraniotis, Aspasia Rigopoulou, Theodore Petsas
Introduction: Low back pain (LBP) is common in children and adolescents. There are many factors that cause LBP, including structural disorders, degenerative changes, Scheuermann's disease, fractures, inflammation, and tumors. Magnetic Resonance Imaging is the gold standard for diagnosing spinal abnormalities and is mandatory when neurological symptoms exist. The study focuses on common MRI findings in adolescents with persistent LBP, without history of acute trauma or evidence of either inflammatory or rheumatic disease...
2018: Radiology Research and Practice
https://www.readbyqxmd.com/read/29578876/surgical-strategies-to-prevent-adjacent-segment-disease-in-the-cervical-spine
#10
Joseph S Butler, Patrick B Morrissey, Scott C Wagner, I David Kaye, Arjun S Sebastian, Gregory D Schroeder, Alexander R Vaccaro, Alan S Hilibrand
The most popular approach to treating symptomatic cervical disk disease is anterior cervical discectomy and fusion. Although this procedure has significant long-term clinical success, it is associated with progressive adjacent segment degeneration with an annual incidence of ∼3%. Total disk arthroplasty was designed as an alternative to fusion that could preserve segmental motion at the operative level and potentially delay or prevent adjacent-level breakdown. The etiology of adjacent segment pathology (ASP) is multifactorial, and it is likely that most cases of ASP are unavoidable...
March 23, 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29573581/automatic-segmentation-of-pigment-deposits-in-retinal-fundus-images-of-retinitis-pigmentosa
#11
Nadia Brancati, Maria Frucci, Diego Gragnaniello, Daniel Riccio, Valentina Di Iorio, Luigi Di Perna
Retinitis Pigmentosa is an eye disease that presents with a slow loss of vision and then evolves until blindness results. The automatic detection of the early signs of retinitis pigmentosa acts as a great support to ophthalmologists in the diagnosis and monitoring of the disease in order to slow down the degenerative process. A large body of literature is devoted to the analysis of Retinitis Pigmentosa. However, all the existing approaches work on Optical Coherence Tomography (OCT) data, while hardly any attempts have been made working on fundus images...
March 17, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/29569159/percutaneous-cement-discoplasty-for-the-treatment-of-advanced-degenerative-disk-disease-in-elderly-patients
#12
Carlos Sola, Gaston Camino Willhuber, Gonzalo Kido, Matias Pereira Duarte, Mariana Bendersky, Maximiliano Mereles, Matias Petracchi, Marcelo Gruenberg
PURPOSE: The authors describe a percutaneous technique to treat advanced degenerative disk disease in elderly patients. METHOD: A step-by-step technical description based on our experience in selected cases. RESULT: Postoperative imaging results are presented as well as indications and recommendations. CONCLUSION: Percutaneous discoplasty can result as an alternative minimal invasive strategy for the treatment of advanced degenerative disk disease...
March 23, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29564803/the-impact-of-ocular-manifestations-of-rheumatoid-arthritis-on-the-health-related-quality-of-life-and-the-functional-ability-of-black-africans
#13
Richard Oluyinka Akintayo, Olufemi Oladipo Adelowo, Ochuko Egajifo, Rukayyah Abisoye Popoola, Gbenga Joshua Odunlami, Airenakho Emorinken, Babatunde Hakeem Olaosebikan
Objectives To determine the patterns, predictors and overall impact of ocular manifestations of rheumatoid arthritis (RA) on the health-related quality of life and disability index. METHODS: A total of 50 Nigerian patients with RA were studied. Full ocular evaluation was done to determine the presence of each defined ocular manifestation of RA. All patients completed the Medical Outcome Study 36-Item Short Form Health Survey (SF-36) and the Health Assessment Questionnaire-Disability Index (HAQ-DI) questionnaires...
March 21, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29553897/characteristics-of-and-risk-factors-for-intervertebral-disk-extrusions-in-pekingese
#14
Orit Chai, Tamar Harrosh, Tali Bdolah-Avram, Michal Mazaki-Tovi, Merav H Shamir
OBJECTIVE To characterize and identify risk factors for intervertebral disk extrusion (IVDE) in Pekingese. DESIGN Retrospective case-control study. ANIMALS 426 Pekingese (81 with confirmed IVDE and 345 without IVDE) admitted to a veterinary teaching hospital from 2005 through 2015. PROCEDURES Medical records were reviewed and data were extracted regarding age, sex, body weight, body condition score, coat color, chief reason for initial evaluation, body system involved, and diagnosis. Survey radiographs of the vertebral column were examined...
April 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29552029/localizing-optic-disc-in-retinal-image-automatically-with-entropy-based-algorithm
#15
Lamia AbedNoor Muhammed
Examining retinal image continuously plays an important role in determining human eye health; with any variation present in this image, it may be resulting from some disease. Therefore, there is a need for computer-aided scanning for retinal image to perform this task automatically and accurately. The fundamental step in this task is identification of the retina elements; optical disk localization is the most important one in this identification. Different optical disc localization algorithms have been suggested, such as an algorithm that would be proposed in this paper...
2018: International Journal of Biomedical Imaging
https://www.readbyqxmd.com/read/29548949/predictive-factors-of-successful-percutaneous-cervical-nucleoplasty-for-the-treatment-of-pain-with-cervical-herniated-disk
#16
Min Kyoung Kim, Sung Eun Sim, Yong-Chul Kim, Jung Soo Kim, Seok Min Kwon, Yongjae Yoo, Chang-Soon Lee, Jee Youn Moon
BACKGROUND: Percutaneous cervical nucleoplasty (PCN) is an effective treatment for cervical herniated intervertebral disc (C-HIVD). In this retrospective study, we evaluated clinical predictors that affect the successful outcome of PCN. METHODS: Fluoroscopy-guided PCN was conducted for C-HIVD by one pain physician. Successful outcome was defined as a combination of > 50% pain relief on the numerical rating scale (NRS) pain score, no increase in analgesics, and no cervical epidural steroid injection during the 3-month follow-up period...
March 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29533788/biomaterial-scaffolds-for-non-invasive-focal-hyperthermia-as-a-potential-tool-to-ablate-metastatic-cancer-cells
#17
Francisco Pelaez, Navid Manuchehrabadi, Priyatanu Roy, Harishankar Natesan, Yiru Wang, Emilian Racila, Heather Fong, Kevin Zeng, Abby M Silbaugh, John C Bischof, Samira M Azarin
Currently, there are very few therapeutic options for treatment of metastatic disease, as it often remains undetected until the burden of disease is too high. Microporous poly(ε-caprolactone) biomaterials have been shown to attract metastasizing breast cancer cells in vivo early in tumor progression. In order to enhance the therapeutic potential of these scaffolds, they were modified such that infiltrating cells could be eliminated with non-invasive focal hyperthermia. Metal disks were incorporated into poly(ε-caprolactone) scaffolds to generate heat through electromagnetic induction by an oscillating magnetic field within a radiofrequency coil...
February 28, 2018: Biomaterials
https://www.readbyqxmd.com/read/29497616/magnetic-resonance-imaging-signal-alterations-in-paraspinal-muscles-in-dogs-with-acute-thoracolumbar-intervertebral-disk-extrusion
#18
Peter Trampus, Christine Goepfert, Monika Welle, Diana Henke, Franck Forterre, Daniela Schweizer-Gorgas
Muscle signal alteration detected on MRI is seen in diverse pathologic conditions. We observed signal alterations within the paraspinal muscles in dogs with acute thoracolumbar intervertebral disk extrusion. The aim of this retrospective study was to describe MRI features of paraspinal muscle signal alteration in dogs with acute thoracolumbar intervertebral disk extrusion and to investigate an association of the signal alterations with neurological grade, type and location of intervertebral disk extrusion, degree of spinal cord compression, and presence of epidural hemorrhage...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29489565/effect-of-optic-disk-fovea-distance-on-measurements-of-individual-macular-intraretinal-layers-in-normal-subjects
#19
Kunliang Qiu, Binyao Chen, Haoyu Chen, Enting Gao, Jianling Yang, Xinjian Chen, Mingzhi Zhang
PURPOSE: To investigate the effect of optic disk-fovea distance (DFD) on measurements of macular intraretinal layers using spectral domain optical coherence tomography in normal subjects. METHODS: One hundred and eighty-two eyes from 182 normal subjects were imaged using spectral domain optical coherence tomography. The average thicknesses of eight macular intraretinal layers were measured using an automatic segmentation algorithm. Partial correlation test and multiple regression analysis were used to determine the effect of DFD on thicknesses of intraretinal layers...
February 27, 2018: Retina
https://www.readbyqxmd.com/read/29488585/-epidemiology-and-antifungal-susceptibility-of-species-producing-candidemia-in-valdivia-chile
#20
Francisco Márquez, Isabel Iturrieta, Mario Calvo, Milton Urrutia, Patricio Godoy-Martínez
BACKGROUND: Candidemia disease in Chile is not very known, despite being a very common and serious disease. AIM: To analyze incidence and susceptibility profile of species from the genus Candida in Hospital Base Valdivia. MATERIAL AND METHODS: All candidemia cases presented between March 2009 and August 2011 in our institution were identified. Species distribution and susceptibility were studied through the disk diffusion method. RESULTS: Twenty-seven candidemia episodes were studied...
October 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
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