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https://www.readbyqxmd.com/read/27920753/neuroproteomics-and-systems-biology-approach-to-identify-temporal-biomarker-changes-post-experimental-traumatic-brain-injury-in-rats
#1
Firas H Kobeissy, Joy D Guingab-Cagmat, Zhiqun Zhang, Ahmed Moghieb, Olena Y Glushakova, Stefania Mondello, Angela M Boutté, John Anagli, Richard Rubenstein, Hisham Bahmad, Amy K Wagner, Ronald L Hayes, Kevin K W Wang
Traumatic brain injury (TBI) represents a critical health problem of which diagnosis, management, and treatment remain challenging. TBI is a contributing factor in approximately one-third of all injury-related deaths in the United States. The Centers for Disease Control and Prevention estimate that 1.7 million people suffer a TBI in the United States annually. Efforts continue to focus on elucidating the complex molecular mechanisms underlying TBI pathophysiology and defining sensitive and specific biomarkers that can aid in improving patient management and care...
2016: Frontiers in Neurology
https://www.readbyqxmd.com/read/27917586/a-qualitative-perspectival-review-of-the-australian-and-new-zealand-urology-education-and-training-program
#2
Prem Rashid
INTRODUCTION: The Australian and New Zealand (ANZ) urology training program was assessed via a prospective, qualitative review to explore the challenges facing the delivery of high quality urological training now and into the future. AIM: To report the reflective considerations and opinions of leaders in the ANZ urological surgical training program. METHODS: Ethics approved semi-structured, template-based, qualitative interview techniques were employed to evaluate key aspects of the current urology training program...
December 5, 2016: BJU International
https://www.readbyqxmd.com/read/27896801/from-threat-to-gradual-lifestyle-changes-iranians-experiences-with-chronic-illnesses
#3
H Vahedparast, E Mohammadi, F Ahmadi
AIM: This study aimed to explore and describe the experience of making a healthy lifestyle change among the patients with chronic illness. BACKGROUND: Despite the existence of different evidence on the critical role of lifestyle in the prevention and management of chronic diseases, many people face challenges in terms of starting and maintaining a healthy lifestyle. METHODS: A descriptive qualitative study with in-depth semi-structured interviews was carried out in 2015 in Iran...
November 28, 2016: International Nursing Review
https://www.readbyqxmd.com/read/27884132/healthy-and-productive-workers-using-intervention-mapping-to-design-a-workplace-health-promotion-and-wellness-program-to-improve-presenteeism
#4
Carlo Ammendolia, Pierre Côté, Carol Cancelliere, J David Cassidy, Jan Hartvigsen, Eleanor Boyle, Sophie Soklaridis, Paula Stern, Benjamin Amick
BACKGROUND: Presenteeism is a growing problem in developed countries mostly due to an aging workforce. The economic costs related to presenteeism exceed those of absenteeism and employer health costs. Employers are implementing workplace health promotion and wellness programs to improve health among workers and reduce presenteeism. How best to design, integrate and deliver these programs are unknown. The main purpose of this study was to use an intervention mapping approach to develop a workplace health promotion and wellness program aimed at reducing presenteeism...
November 25, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27881163/assessing-the-feasibility-of-a-web-based-domestic-violence-intervention-using-chronic-disease-frameworks-reducing-the-burden-of-treatment-and-promoting-capacity-for-action-in-women-abused-by-a-partner
#5
Laura Tarzia, Carl May, Kelsey Hegarty
BACKGROUND: Domestic violence shares many features with chronic disease, including ongoing physical and mental health problems and eroded self-efficacy. Given the challenges around help-seeking for women experiencing domestic violence, it is essential that they be given support to 'self-manage' their condition. The growing popularity of web-based applications for chronic disease self-management suggests that there may be opportunities to use them as an intervention strategy for women experiencing domestic violence, however, as yet, little is known about whether this might work in practice...
November 24, 2016: BMC Women's Health
https://www.readbyqxmd.com/read/27879168/situation-criticality-and-basketball-officials-stress-levels
#6
Jason Ritchie, Itay Basevitch, Ryan Rodenberg, Gershon Tenenbaum
Officials are expected to perform impeccably despite the wide range of stressors they experience. A stressor that officials frequently report is situation criticality. Situation criticality is comprised of score differential (i.e., more pressure in close games) and time remaining in a game (i.e., more pressure as time expires), which affects athletes' stress levels. The present study explored the effect of situation criticality on officials' stress levels. High school basketball officials (n = 108) with an average of 18...
November 23, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27876411/disruption-of-mitochondrial-quality-control-in-peripheral-artery-disease-new-therapeutic-opportunities
#7
REVIEW
Cintia B Ueta, Katia S Gomes, Márcio A Ribeiro, Daria Mochly-Rosen, Julio C B Ferreira
Peripheral artery disease (PAD) is a multifactorial disease initially triggered by reduced blood supply to the lower extremities due to atherosclerotic obstructions. It is considered a major public health problem worldwide, affecting over 200 million people. Management of PAD includes smoking cessation, exercise, statin therapy, antiplatelet therapy, antihypertensive therapy and surgical intervention. Although these pharmacological and non-pharmacological interventions usually increases blood flow to the ischemic limb, morbidity and mortality associated with PAD continue to increase...
November 19, 2016: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/27876164/measuring-the-environmental-sustainability-performance-of-global-supply-chains-a-multi-regional-input-output-analysis-for-carbon-sulphur-oxide-and-water-footprints
#8
Adolf Acquaye, Kuishuang Feng, Eunice Oppon, Said Salhi, Taofeeq Ibn-Mohammed, Andrea Genovese, Klaus Hubacek
Measuring the performance of environmentally sustainable supply chains instead of chain constitute has become a challenge despite the convergence of the underlining principles of sustainable supply chain management. This challenge is exacerbated by the fact that supply chains are inherently dynamic and complex and also because multiple measures can be used to characterize performances. By identifying some of the critical issues in the literature regarding performance measurements, this paper contributes to the existing body of literature by adopting an environmental performance measurement approach for economic sectors...
November 18, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27871566/known-difficult-airway-in-a-patient-with-pheochromocytoma-a-case-report
#9
Laura Alonso Guardo, Carlos Cano Gala, Antonio Rodriguez Calvo, Adriana M Buritica Aguirre, Nadia A Dávila Arango, Elena García Fernández, Carmen Ruiz Chirosa, David Sánchez Poveda, Agustín Díaz Álvarez
: The manipulation of an airway is always a critical moment in the anesthetic management of patients with pheochromocytoma due to the high incidence of undesirable hemodynamic events in relation with the stimulus represented by the laryngoscopy. A known difficult airway in which it is necessary to carry out an orotracheal intubation while preserving spontaneous ventilation subjects the patient to a stressful situation. The objective is to obtain an acceptable level of comfort and sedation avoiding respiratory depression (Anesthesiol Clin 2015;33:233-40)...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27862556/persistence-of-trophic-hotspots-and-relation-to-human-impacts-within-an-upwelling-marine-ecosystem
#10
Jarrod A Santora, William J Sydeman, Isaac D Schroeder, John C Field, Rebecca R Miller, Brian K Wells
Human impacts (e.g., fishing, pollution and shipping) on pelagic ecosystems are increasing, causing concerns about stresses on marine food webs. Maintaining predator-prey relationships through protection of pelagic hotspots is crucial for conservation and management of living marine resources. Biotic components of pelagic, plankton-based, ecosystems exhibit high variability in abundance in time and space (i.e., extreme patchiness), requiring investigation of persistence of abundance across trophic levels to resolve trophic hotspots...
November 11, 2016: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/27858206/exploring-the-need-for-interventions-to-manage-weight-and-stress-during-interconception
#11
Jennifer Huberty, Jenn A Leiferman, Abbey R Kruper, Lisette T Jacobson, Molly E Waring, Jeni L Matthews, Danielle M Wischenka, Betty Braxter, Sara L Kornfield
Interventions to manage weight and stress during the interconception period (i.e., time immediately following childbirth to subsequent pregnancy) are needed to promote optimal maternal and infant health outcomes. To address this gap, we summarize the current state of knowledge, critically evaluate the research focused on weight and stress management during the interconception period, and provide future recommendations for research in this area. Evidence supports the importance of weight and stress management during the reproductive years and the impact of weight on maternal and child health outcomes...
November 17, 2016: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/27846124/effectiveness-and-experiences-of-families-and-support-workers-participating-in-peer-led-parenting-support-programs-delivered-as-home-visiting-programs-a-comprehensive-systematic-review
#12
Ailsa Munns, Robin Watts, Desley Hegney, Roz Walker
BACKGROUND: Designing child and family health services to meet the diverse needs of contemporary families is intended to minimize impacts of early disadvantage and subsequent lifelong health and social issues. Innovative programs to engage families with child and family support services have led to interest in the potential value of peer-led home visiting from parents in local communities. There is a range of benefits and challenges identified in a limited number of studies associated with home visiting peer support...
October 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27846092/pilot-mechanistic-study-of-insulin-modulation-of-somatotrophic-hormones-inflammation-and-lipid-metabolism-during-critical-illness-in-children
#13
Ricardo G Branco, Pedro Celiny R Garcia, Jefferson P Piva, Geniara S Conrado, Felipe Cabral, Cecilia Korb, Humberto Fiori, Matteo Baldisserotto, Robert C Tasker
OBJECTIVES: To evaluate the mechanism of insulin modulation on somatotrophic response, inflammation, and lipid metabolism in critically ill children. DESIGN: Open-label randomized mechanistic study. SETTING: Two-center, tertiary PICU study. PATIENTS: Thirty critically ill children between 1 month and 14 years old, requiring mechanical ventilation and with evidence of two or more organ system failures. INTERVENTIONS: Randomized physiologic design of hyperinsulinemic-euglycemic clamp using continuous insulin infusion at 0...
November 11, 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27833921/management-of-patient-care-in-hemodialysis-while-focusing-on-cardiovascular-disease-events-and-the-atypical-role-of-hyper-and-or-hypotension-a-systematic-review
#14
REVIEW
Amjad Khan, Amer Hayat Khan, Azreen Syazril Adnan, Syed Azhar Syed Sulaiman, Siew Hua Gan, Irfanullah Khan
Background. Hemodialysis related hemodynamic instability is a major but an underestimated issue. Moreover, cardiovascular events are the leading cause of morbidity and mortality associated with blood pressure in hemodialysis patients. However, there have been many controversies regarding the role and management of hyper- and/or hypotension during hemodialysis that needs to be addressed. Objective. To critically review the available published data on the atypical role of hyper- and/or hypotension in cardiovascular associated morbidity and mortality in patients on hemodialysis and to understand the discrepancies in this context...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27828972/coral-reefs-and-people-in-a-high-co2-world-where-can-science-make-a-difference-to-people
#15
Linwood Pendleton, Adrien Comte, Chris Langdon, Julia A Ekstrom, Sarah R Cooley, Lisa Suatoni, Michael W Beck, Luke M Brander, Lauretta Burke, Josh E Cinner, Carolyn Doherty, Peter E T Edwards, Dwight Gledhill, Li-Qing Jiang, Ruben J van Hooidonk, Louise Teh, George G Waldbusser, Jessica Ritter
REEFS AND PEOPLE AT RISK: Increasing levels of carbon dioxide in the atmosphere put shallow, warm-water coral reef ecosystems, and the people who depend upon them at risk from two key global environmental stresses: 1) elevated sea surface temperature (that can cause coral bleaching and related mortality), and 2) ocean acidification. These global stressors: cannot be avoided by local management, compound local stressors, and hasten the loss of ecosystem services. Impacts to people will be most grave where a) human dependence on coral reef ecosystems is high, b) sea surface temperature reaches critical levels soonest, and c) ocean acidification levels are most severe...
2016: PloS One
https://www.readbyqxmd.com/read/27828796/perioperative-anesthesia-care-and-tumor-progression
#16
Mir W Sekandarzad, André A J van Zundert, Philipp B Lirk, Chris W Doornebal, Markus W Hollmann
This narrative review discusses the most recent up-to-date findings focused on the currently available "best clinical practice" regarding perioperative anesthesia care bundle factors and their effect on tumor progression. The main objective is to critically appraise the current literature on local anesthetics, regional outcome studies, opioids, and nonsteroidal anti-inflammatory drugs (NSAIDs) and their ability to decrease recurrence in patients undergoing cancer surgery. A brief discussion of additional topical perioperative factors relevant to the anesthesiologist including volatile and intravenous anesthetics, perioperative stress and anxiety, nutrition, and immune stimulation is included...
November 8, 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27803840/experiences-and-psychosocial-impact-of-west-africa-ebola-deployment-on-us-health-care-volunteers
#17
Robyn Gershon, Liza A Dernehl, Ezinne Nwankwo, Qi Zhi, Kristine Qureshi
BACKGROUND:  This qualitative study was designed to assess health care volunteers' experiences and psychosocial impacts associated with deployment to the West Africa Ebola epidemic. METHODS: In 2015, using snowball sampling, 16 US health care volunteers who had recently returned from West Africa were recruited for this study. Semi-structured interviews were conducted to collect information associated with each phase of deployment (pre, peri, and post). RESULTS: Participants reported that they were motivated to volunteer because of a sense of responsibility and feelings of empathy and altruism...
September 21, 2016: PLoS Currents
https://www.readbyqxmd.com/read/27801710/glucocortiosteroid-subsensitivity-and-asthma-severity
#18
Manali Mukherjee, Sarah Svenningsen, Parameswaran Nair
PURPOSE OF REVIEW: Glucocorticosteroids (GCSs) remain the cornerstone of therapy for treating the inflammatory component of asthma. Clinical response to GCS is heterogeneous, varying both within asthma 'endotypes', as well as the same individual. Different factors and micro-environment can alter the canonical GCS-induced signalling pathways leading to reduced efficacy, collectively termed as GCS subsensitivity, which includes the entire spectrum of steroid insensitivity and steroid resistance...
January 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/27791055/linking-freshwater-fishery-management-to-global-food-security-and-biodiversity-conservation
#19
Peter B McIntyre, Catherine A Reidy Liermann, Carmen Revenga
Fisheries are an essential ecosystem service, but catches from freshwaters are often overlooked. Hundreds of millions of people around the world benefit from low-cost protein, recreation, and commerce provided by freshwater fisheries, particularly in regions where alternative sources of nutrition and employment are scarce. Here, we derive a gridded global map of riverine fisheries and assess its implications for biodiversity conservation, fishery sustainability, and food security. Catches increase with river discharge and human population density, and 90% of global catch comes from river basins with above-average stress levels...
October 24, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27779820/provider-perspectives-on-safety-in-primary-care-in-albania
#20
Jonila Cyco Gabrani, Wendy Knibb, Elizana Petrela, Adrian Hoxha, Adriatik Gabrani
PURPOSE: The purpose of this study was to determine the safety attitudes of specialist physicians (SPs), general physicians (GPs), and nurses in primary care in Albania. DESIGN: The study was cross-sectional. It involved the SPs, GPs, and nurses from five districts in Albania. A demographic questionnaire and the adapted Safety Attitudes Questionnaire (SAQ)-Long Ambulatory Version A was used to gather critical information regarding the participant's profile, perception of management, working conditions, job satisfaction, stress recognition, safety climate, and perceived teamwork...
October 25, 2016: Journal of Nursing Scholarship
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