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https://www.readbyqxmd.com/read/28183438/cardiac-imaging-for-assessing-low-gradient-severe-aortic-stenosis
#1
REVIEW
Marie-Annick Clavel, Ian G Burwash, Philippe Pibarot
Up to 40% of patients with aortic stenosis (AS) harbor discordant Doppler-echocardiographic findings, the most common of which is the presence of a small aortic valve area (≤1.0 cm(2)) suggesting severe AS, but a low gradient (<40 mm Hg) suggesting nonsevere AS. The purpose of this paper is to present the role of multimodality imaging in the diagnostic and therapeutic management of this challenging entity referred to as low-gradient AS. Doppler-echocardiography is critical to determine the subtype of low-gradient AS: that is, classical low-flow, paradoxical low-flow, or normal-flow...
February 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28183072/alternative-therapies-for-excoriation-skin-picking-disorder-a-brief-update
#2
Julio Torales, Iván Barrios, Jorge Villalba
Context • Excoriation (skin picking) disorder is characterized by the need or urge to pick, scratch, pinch, touch, rub, scrub, squeeze, bite, or dig the skin, and it can be a perplexing condition for the inexperienced physician. Treatments include pharmacotherapy, psychotherapy, and alternative therapies. Alternative therapies for excoriation disorder and other body-focused repetitive behaviors include yoga, aerobic exercise, acupuncture, biofeedback, hypnosis, and inositol and N-acetylcysteine, among others...
January 2017: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/28178022/the-impact-of-essential-fatty-acid-b-vitamins-vitamin-c-magnesium-and-zinc-supplementation-on-stress-levels-in-women-a-systematic-review
#3
Delia McCabe, Karolina Lisy, Craig Lockwood, Marc Colbeck
BACKGROUND: Women juggling multiple roles in our complex society are increasingly experiencing psychological stress. Dietary supplementation to manage stress is widespread despite limited supporting evidence. A systematic review of the available literature was undertaken to investigate the efficacy of specific dietary supplements in managing female stress and anxiety. OBJECTIVES: To identify the impact of essential fatty acids (EFAs), B vitamins, vitamin C, magnesium and/or zinc, consumed as dietary supplements to the daily diet, on female stress and anxiety levels...
February 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28168021/refuge-or-predation-risk-alternate-ways-to-perceive-hiker-disturbance-based-on-maternal-state-of-female-caribou
#4
Frédéric Lesmerises, Chris J Johnson, Martin-Hugues St-Laurent
Human presence in natural environments is often a source of stress that is perceived by large ungulates as an increased risk of predation. Alternatively, disturbance induced by hikers creates a relatively predator-free space that may serve as a refuge. We measured the behavioral responses of female caribou to disturbance associated with the presence of hikers during summer in the Gaspésie National Park. We used those data to determine whether caribou responded negatively to human activity (i.e., the predation risk hypothesis) or whether human activity resulted in a decrease in the magnitude of perceived risk (i...
February 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28164521/using-the-expression-of-damage-associated-molecular-pattern-damp-for-the-evaluation-and-monitoring-of-the-critically-ill-polytrauma-patient
#5
REVIEW
Marius Papurica, Alexandru F Rogobete, Dorel Sandesc, Carmen A Cradigati, Mirela Sarandan, Raluca Dumache, Florin G Horhat, Lavinia M Bratu, Razvan Nitu, Dan C Crisan, Delia I Horhat, Elena S Popovici, Sonia Tanasescu, Vlad Daliborca, Ovidiu Boruga, Ovidiu H Bedreag
BACKGROUND: The critically ill polytrauma patient continues to be one of the most complex cases in the intensive care unit (ICU). The molecular damage is closely connected with the severe, specific pathophysiological imbalances, such as severe inflammation, infections, hypermetabolism, oxidative stress, and ultimately multiple organ dysfunction syndrome (MODS). METHODS: The literature available on PubMed and Scopus was analysed for this study. The key words used in the search were "biomarkers in critically ill patients", "molecular damage", "sepsis biomarkers", "miRNAs biomarkers", and "oxidative stress"...
October 1, 2016: Clinical Laboratory
https://www.readbyqxmd.com/read/28159664/young-adults-use-of-emotional-food-memories-to-build-resilience
#6
Elisabeth von Essen, Fredrika Mårtensson
The overall aim of this study is to specifically investigate how young adults make use of emotional-relational food memories related to "significant others" during childhood when trying to build resilience and solve developmental tasks in this period of life. A theoretical sample of three semi-structured interviews drawn from a larger sample of 30 interviews with young adults in Sweden formed the basis for analysis, guided by the steps of a phenomenologically oriented critical narrative analysis. The results illustrate three different overall directions in how the relationship to food can evolve throughout life among young adults: a relationship dominated by 1) positive emotional food memories associated with the use of food as a secure base and 2) negative emotional food memories associated with either a) being emotionally preoccupied with food or b) dismissing food...
January 31, 2017: Appetite
https://www.readbyqxmd.com/read/28144160/association-between-lymphocyte-expression-of-the-apoptotic-receptor-fas-and-pain-in-critically-ill-patients
#7
Elizabeth DE Papathanassoglou, Meropi DA Mpouzika, Margarita Giannakopoulou, Evangelos Bozas, Nicos Middleton, George Tsiaousis, Andreas Karabinis
OBJECTIVE: Lymphocyte apoptosis in critical illness is associated with immunosuppression. We explored for the first time the associations between pain ratings and expression of the apoptotic receptor Fas on B and T cells in critically ill patients and the potential mediating effects of adrenocorticotropic hormone (ACTH), cortisol, and substance P (SP). DESIGN: This is an exploratory correlational study with repeated measurements (14 days followup) and cross-sectional comparisons...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28125983/fathers-views-and-experiences-of-their-own-mental-health-during-pregnancy-and-the-first-postnatal-year-a-qualitative-interview-study-of-men-participating-in-the-uk-born-and-bred-in-yorkshire-baby-cohort
#8
Z Darwin, P Galdas, S Hinchliff, E Littlewood, D McMillan, L McGowan, S Gilbody
BACKGROUND: The prevalence of fathers' depression and anxiety in the perinatal period (i.e. from conception to 1 year after birth) is approximately 5-10%, and 5-15%, respectively; their children face increased risk of adverse emotional and behavioural outcomes, independent of maternal mental health. Critically, fathers can be protective against the development of maternal perinatal mental health problems and their effects on child outcomes. Preventing and treating paternal mental health problems and promoting paternal psychological wellbeing may therefore benefit the family as a whole...
January 26, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28116619/hdac6-regulates-sensitivity-to-cell-death-in-response-to-stress-and-post-stress-recovery
#9
Hyun-Wook Ryu, Hye-Rim Won, Dong Hoon Lee, So Hee Kwon
Histone deacetylase 6 (HDAC6) plays an important role in stress responses such as misfolded protein-induced aggresomes, autophagy, and stress granules. However, precisely how HDAC6 manages response during and after cellular stress remains largely unknown. This study aimed to investigate the effect of HDAC6 on various stress and post-stress recovery responses. We showed that HIF-1α protein levels were reduced in HDAC6 knockout (KO) MEFs compared to wild-type (WT) MEFs in hypoxia. Furthermore, under hypoxia, HIF-1α levels were also reduced following rescue with either a catalytically inactive or a ubiqiutin-binding mutant HDAC6...
January 23, 2017: Cell Stress & Chaperones
https://www.readbyqxmd.com/read/28115381/adaptive-evolution-of-extreme-acidophile-sulfobacillus-thermosulfidooxidans-potentially-driven-by-horizontal-gene-transfer-and-gene-loss
#10
Xian Zhang, Xueduan Liu, Yili Liang, Xue Guo, Yunhua Xiao, Liyuan Ma, Bo Miao, Hongwei Liu, Deliang Peng, Wenkun Huang, Yuguang Zhang, Huaqun Yin
: Recent phylogenomic analysis has suggested that three strains isolated from different copper mine tailings around the world were taxonomically affiliated with Sulfobacillus thermosulfidooxidans Here, we present a detailed investigation of their genomic features, particularly with respect to metabolic potentials and stress tolerance mechanisms. Comprehensive analysis of the Sulfobacillus genomes identified a core set of essential genes with specialized biological functions in the survival of acidophiles in their habitats, despite differences in their metabolic pathways...
January 23, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28111628/the-prefrontal-cortex-as-a-critical-gate-of-negative-affect-and-motivation-in-alcohol-use-disorder
#11
Amanda R Pahng, M Adrienne McGinn, Rod I Paulsen, Scott Edwards
The prefrontal cortex (PFC) represents and executes the highest forms of goal-directed behavior, and has thereby attained a central neuroanatomical position in most pathophysiological conceptualizations of motivational disorders, including alcohol use disorder (AUD). Excessive, intermittent exposure to alcohol produces an allostatic dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis along with heightened forebrain glucocorticoid signaling that can damage PFC architecture and function. Negative affective states intimately associated with the transition to alcohol dependence result not only from a dysregulated HPA axis, but also from the inability of a damaged PFC to regulate subcortical stress and reinforcement centers, including the ventral striatum and amygdala...
February 2017: Current Opinion in Behavioral Sciences
https://www.readbyqxmd.com/read/28106853/significant-change-spotting-for-periodic-human-motion-segmentation-of-cleaning-tasks-using-wearable-sensors
#12
Kai-Chun Liu, Chia-Tai Chan
The proportion of the aging population is rapidly increasing around the world, which will cause stress on society and healthcare systems. In recent years, advances in technology have created new opportunities for automatic activities of daily living (ADL) monitoring to improve the quality of life and provide adequate medical service for the elderly. Such automatic ADL monitoring requires reliable ADL information on a fine-grained level, especially for the status of interaction between body gestures and the environment in the real-world...
January 19, 2017: Sensors
https://www.readbyqxmd.com/read/28074555/pediatric-stress-from-neuroendocrinology-to-contemporary-disorders
#13
REVIEW
Stavroula Stavrou, Nicolas C Nicolaides, Elena Critselis, Christina Darviri, Evangelia Charmandari, George P Chrousos
BACKGROUND: Stress is defined as a state of threatened or perceived as threatened homeostasis. A broad spectrum of extrinsic or intrinsic, real or perceived stressful stimuli, called "stressors", activates a highly conserved system, the "stress system", which adjusts homeostasis through central and peripheral neuroendocrine responses. Inadequate, excessive or prolonged adaptive responses to stress may underlie the pathogenesis of several disease states prevalent in modern societies. The development and severity of these conditions primarily depend on the genetic vulnerability of the individual, the exposure to adverse environmental factors and the timing of the stressful event(s), given that prenatal life, infancy, childhood and adolescence are critical periods characterized by increased vulnerability to stressors...
January 11, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28073739/the-associations-among-individual-factors-ehealth-literacy-and-health-promoting-lifestyles-among-college-students
#14
Shu-Ching Yang, Yi-Fang Luo, Chia-Hsun Chiang
BACKGROUND: eHealth literacy is gaining importance for maintaining and promoting health. Studies have found that individuals with high eHealth literacy are more likely to adopt healthy eating, exercise, and sleep behaviors. In addition, previous studies have shown that various individual factors (eg, frequency of seeking information on health issues, degree of health concern, frequency of eating organic food, and students' college major) are associated with eHealth literacy and health-promoting lifestyles...
January 10, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28072938/welfare-of-anaesthesia-trainees-survey
#15
G B Downey, J M McDonald, R G Downey
This study was designed to investigate levels of stress, anxiety or depression and to identify factors compounding or relieving stress in anaesthesia trainees within the Australian and New Zealand College of Anaesthetists (ANZCA) training scheme. An electronic survey was sent to 999 randomly selected trainees and 428 responses were received. In addition to demographics, psychological wellbeing was assessed using the Kessler Psychological Distress Scale (K10) and questions were asked about depression and anxiety, exacerbating factors, personal healthcare and strategies used to manage stress...
January 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28070611/dual-mobility-cups-provide-biomechanical-advantages-in-situations-at-risk-for-dislocation-a-finite-element-analysis
#16
Alexandre Terrier, Adeliya Latypova, Maika Guillemin, Valérie Parvex, Olivier Guyen
PURPOSE: Constrained devices, standard implants with large heads, and dual mobility systems have become popular options to manage instability after total hip arthroplasty (THA). Clinical results with these options have shown variable success rates and significant higher rates of aseptic loosening and mechanical failures with constrained implants. Literature suggests potential advantages of dual mobility, however little is known about its biomechanics. We present a comparative biomechanical study of a standard implant, a constrained implant, and a dual mobility system...
January 9, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28069528/personal-and-professional-well-being-of-surgical-residents-in-new-england
#17
Peter S Yoo, John J Tackett, Mark W Maxfield, Rosemarie Fisher, Stephen J Huot, Walter E Longo
BACKGROUND: Although there is increasing literature about burnout and attrition among surgeons, little is known about personal and professional well-being of surgical trainees. STUDY DESIGN: General surgery residents from the six New England states participated in a cross-sectional, qualitative, self-reported survey to assess the domains of personal health maintenance, personal finance, work environment, and fatigue management as they relate to surgical training...
January 6, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28058409/finding-significant-stress-episodes-in-a-discontinuous-time-series-of-rapidly-varying-mobile-sensor-data
#18
Hillol Sarker, Matthew Tyburski, Md Mahbubur Rahman, Karen Hovsepian, Moushumi Sharmin, David H Epstein, Kenzie L Preston, C Debra Furr-Holden, Adam Milam, Inbal Nahum-Shani, Mustafa al'Absi, Santosh Kumar
Management of daily stress can be greatly improved by delivering sensor-triggered just-in-time interventions (JITIs) on mobile devices. The success of such JITIs critically depends on being able to mine the time series of noisy sensor data to find the most opportune moments. In this paper, we propose a time series pattern mining method to detect significant stress episodes in a time series of discontinuous and rapidly varying stress data. We apply our model to 4 weeks of physiological, GPS, and activity data collected from 38 users in their natural environment to discover patterns of stress in real-life...
May 2016: Proceedings of the SIGCHI Conference on Human Factors in Computing Systems
https://www.readbyqxmd.com/read/28043180/the-effect-of-body-and-mind-stress-releasing-techniques-on-the-breastfeeding-of-full-term-babies-a-critical-analysis-of-published-interventional-studies
#19
Catherine Fotiou, Tania Siahanidou, Petros V Vlastarakos, Evangelia Filothei Tavoulari, George Chrousos
OBJECTIVE: To critically assess the effectiveness of complementary/alternative medicine modalities, comprising body/mind stress-releasing techniques, on the breastfeeding (BF) success of mothers of full-term newborns. METHODS: Literature review in Medline and other available database sources until December 2015, and critical analysis of pooled data. The study selection included randomized-controlled trials, case-control studies, and case-series. RESULTS: The total number of analyzed studies was 9...
January 2, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28031807/spatial-patterns-of-an-endemic-mediterranean-palm-recolonizing-old-fields
#20
Miguel E Jácome-Flores, Miguel Delibes, Thorsten Wiegand, José M Fedriani
Throughout Europe, increased levels of land abandonment lead to (re)colonization of old lands by forests and shrublands. Very little is known about the spatial pattern of plants recolonizing such old fields. We mapped in two 21-22-ha plots, located in the Doñana National Park (Spain), all adult individuals of the endozoochorous dwarf palm Chamaerops humilisL. and determined their sex and sizes. We used techniques of spatial point pattern analysis (SPPA) to precisely quantify the spatial structure of these C...
December 2016: Ecology and Evolution
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