Michimi Otani, Miki Nishimori, Hitomi Iwasa, Mamiko Iwamura, Takayasu Izumi, Kosuke Nakaji, Noriko Nitta, Kana Miyatake, Rika Yoshimatsu, Tomoaki Yamanishi, Tomohiro Matsumoto, Yasushi Osaki, Noriko Wada, Makoto Toi, Marino Yamamoto, Yu Nakatani, Tetsuya Kubota, Takuji Yamagami
Spontaneous regression (SR) of cancer is very rare, especially of small cell lung cancer (SCLC). Recently, an association of paraneoplastic neurological syndrome (PNS) has been reported as a cause of SR of cancer, and onconeural antibodies are a possible factor in the SR of cancer associated with PNS. We herein report the first case of SR of SCLC combined with anti-P/Q-type of voltage-gated calcium channel (VGCC) antibody-positive Lambert-Eaton myasthenic syndrome (LEMS), a subtype of PNS. This case report suggests that SCLC may be spontaneously reduced by an autoimmune response induced by VGCC antibodies associated with LEMS...
November 2023: Radiology Case Reports