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https://www.readbyqxmd.com/read/29045973/-application-of-three-dimensional-reconstruction-of-the-enhanced-ct-with-iplan-cmf-software-in-head-and-neck-neoplasms
#1
Y Yu, W B Zhang, Y Wang, X J Liu, C B Guo, G Y Yu, X Peng
OBJECTIVE: Three-dimensional reconstruction of the enhanced CT is increasingly becoming a valuable tool in head and neck neoplasms. The aim of this study is to reconstruct three-dimensional imaging of tumor and its surrounding important anatomical structure using iPlan CMF software, and to investigate the application of three-dimensional tumor mapping technique for the diagnosis and treatment of the head and neck neoplasms. METHODS: In the study, 13 cases with head and neck tumors in Department of Oral and Maxilloficial Surgery, Peking University School and Hospital of Stomatology from June 2014 to June 2015 were studied using spiral CT scanning technology based on the same scanning condition...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045969/-clinical-study-on-locking-plate-for-the-treatment-of-non-osteoporotic-complex-proximal-humeral-fractures
#2
X Li, F L Li, Y Lu, Y M Zhu, S Y Guo, Y J Li, C Y Jiang
OBJECTIVE: To describe long-term results of locking plate used for the treatment of non-osteoporotic fresh three- and four-part proximal humeral fractures with at least 2 years follow-up. METHODS: The functional outcomes and the complications of non-osteoporotic three- and four-part fresh proximal humeral fractures treated with locking plate were assessed retrospectively. The active range of motion, the Constant score, the University of California at Los Angeles (UCLA) shoulder score, the visual analogue score (VAS) were employed to evaluate the postoperative shoulder function, and the radiographic images were taken to evaluate the neck-shaft angle of the proximal humeral and postoperative implant-related complications...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045844/a-b-cell-regulome-links-notch-to-downstream-oncogenic-pathways-in-small-b-cell-lymphomas
#3
Russell J H Ryan, Jelena Petrovic, Dylan M Rausch, Yeqiao Zhou, Caleb A Lareau, Michael J Kluk, Amanda L Christie, Winston Y Lee, Daniel R Tarjan, Bingqian Guo, Laura K H Donohue, Shawn M Gillespie, Valentina Nardi, Ephraim P Hochberg, Stephen C Blacklow, David M Weinstock, Robert B Faryabi, Bradley E Bernstein, Jon C Aster, Warren S Pear
Gain-of-function Notch mutations are recurrent in mature small B cell lymphomas such as mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL), but the Notch target genes that contribute to B cell oncogenesis are largely unknown. We performed integrative analysis of Notch-regulated transcripts, genomic binding of Notch transcription complexes, and genome conformation data to identify direct Notch target genes in MCL cell lines. This B cell Notch regulome is largely controlled through Notch-bound distal enhancers and includes genes involved in B cell receptor and cytokine signaling and the oncogene MYC, which sustains proliferation of Notch-dependent MCL cell lines via a Notch-regulated lineage-restricted enhancer complex...
October 17, 2017: Cell Reports
https://www.readbyqxmd.com/read/29045397/glucose-feeds-the-tca-cycle-via-circulating-lactate
#4
Sheng Hui, Jonathan M Ghergurovich, Raphael J Morscher, Cholsoon Jang, Xin Teng, Wenyun Lu, Lourdes A Esparza, Tannishtha Reya, Le Zhan, Jessie Yanxiang Guo, Eileen White, Joshua D Rabinowitz
Mammalian tissues are fuelled by circulating nutrients, including glucose, amino acids, and various intermediary metabolites. Under aerobic conditions, glucose is generally assumed to be burned fully by tissues via the tricarboxylic acid cycle (TCA cycle) to carbon dioxide. Alternatively, glucose can be catabolized anaerobically via glycolysis to lactate, which is itself also a potential nutrient for tissues and tumours. The quantitative relevance of circulating lactate or other metabolic intermediates as fuels remains unclear...
October 18, 2017: Nature
https://www.readbyqxmd.com/read/29045062/tokyo-guidelines-2018-flowchart-for-the-management-of-acute-cholecystitis
#5
Kohji Okamoto, Kenji Suzuki, Tadahiro Takada, Steven M Strasberg, Horacio J Asbun, Itaru Endo, Yukio Iwashita, Taizo Hibi, Henry A Pitt, Akiko Umezawa, Koji Asai, Ho-Seong Han, Tsann-Long Hwang, Yasuhisa Mori, Yoo-Seok Yoon, Wayne Shih-Wei Huang, Giulio Belli, Christos Dervenis, Masamichi Yokoe, Seiki Kiriyama, Takao Itoi, Palepu Jagannath, O James Garden, Fumihiko Miura, Masafumi Nakamura, Akihiko Horiguchi, Go Wakabayashi, Daniel Cherqui, Eduardo de Santibañes, Satoru Shikata, Yoshinori Noguchi, Tomohiko Ukai, Ryota Higuchi, Keita Wada, Goro Honda, Avinash Nivritti Supe, Masahiro Yoshida, Toshihiko Mayumi, Dirk J Gouma, Daniel J Deziel, Kui-Hin Liau, Miin-Fu Chen, Kazunori Shibao, Keng-Hao Liu, Cheng-Hsi Su, Angus C W Chan, Dong-Sup Yoon, In-Seok Choi, Eduard Jonas, Xiao-Ping Chen, Sheung Tat Fan, Chen-Guo Ker, Mariano Eduardo Giménez, Seigo Kitano, Masafumi Inomata, Koichi Hirata, Kazuo Inui, Yoshinobu Sumiyama, Masakazu Yamamoto
We propose a new flowchart for the treatment of acute cholecystitis (AC) in TG18. Grade III AC was not indicated for straightforward laparoscopic cholecystectomy (Lap-C). Following analysis of subsequent clinical investigations and drawing on Big Data in particular, TG18 proposes that some Grade III AC can be treated by Lap-C when performed at advanced centers with specialized surgeons experienced in this procedure and for patients that satisfy certain strict criteria. For Grade I, TG18 recommends early Lap-C if the patients meet the criteria of Charlson Comorbidity Index (CCI)≤5 and American Society of Anesthesiologist physical status classification (ASA-PS)≤2...
October 16, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/29044903/native-t1-mapping-for-characterization-of-acute-and-chronic-myocardial-infarction-in-swine-comparison-with-contrast-enhanced-mri
#6
Xi Liu, Jiang-Long Hou, Zhi-Gang Yang, Chun-Chao Xia, Lin-Jun Xie, Peng-Fei Ye, Wan-Lin Peng, Lei Li, Meng-Xi Yang, Ying-Kun Guo
BACKGROUND: Both acute and chronic myocardial infarction (AMI and CMI, respectively) exhibit delayed enhancement; however, clinical decision-making processes frequently require the differentiation of these two types of myocardial injury. PURPOSE: To investigate the reliability of AMI and CMI characterization using native T1 mapping and its feasibility for discriminating AMI from CMI. STUDY TYPE: Case-control. ANIMAL MODEL: The study cohort comprised 12 AMI (mean post-MI, 3...
October 16, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29044464/prognostic-value-of-the-cancer-oncogene-kelch-like-6-in-gastric-cancer
#7
J Deng, J Guo, G Ma, H Zhang, D Sun, Y Hou, X Xie, X Guo, Y Nie, H Liang
BACKGROUND: Kelch-like 6 (KLHL6) is a cancer oncogene previously associated with specific human cancers, such as chronic lymphocytic leukaemia. Here, the mechanisms of KLHL6 function were explored in gastric cancer (GC) cells, in an in vivo experimental tumour model, and the prognostic value of KLHL6 analysis in GC tissue evaluated in a cohort of patients with GC. METHODS: Associations between clinicopathological and survival data and KLHL6 expression in GC tissues were analysed...
October 17, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/29040727/whole-genome-sequencing-of-african-dogs-provides-insights-into-adaptations-against-tropical-parasites
#8
Yan-Hu Liu, Lu Wang, Tao Xu, Xiaomin Guo, Yang Li, Ting-Ting Yin, He-Chuan Yang, Hu Yang, Adeniyi C Adeola, Oscar J Sanke, Newton O Otecko, Meng Wang, Yaping Ma, Olaogun S Charles, Mikkel-Holger S Sinding, Shyam Gopalakrishnan, José Alfredo Samaniego, Anders J Hansen, Carlos Fernandes, Philippe Gaubert, Jane Budd, Philip M Dawuda, Eli Knispel Rueness, Lubin Jiang, Weiwei Zhai, M T P Gilbert, Min-Sheng Peng, Xiaopeng Qi, Guo-Dong Wang, Ya-Ping Zhang
Natural selection in domestic dogs is of great interest in evolutionary biology since dogs have migrated to every inhabited continent of the world alongside humans, and adapted to diverse environments. Here, we explored their demographic history and genetic basis of adaptation to the tropical African environment using whole genome analyses of 19 African indigenous dogs from Nigeria. Demographic analysis suggests that the ancestors of these dogs migrated into Africa from Eurasia 14,000 years ago and underwent a severe founder effect before population expansion...
October 10, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29040343/spherical-nematic-shells-with-a-prolate-ellipsoidal-core
#9
Monirosadat Sadati, Ye Zhou, Drew Melchert, Ashley Guo, Jose A Martinez-Gonzalez, Tyler F Roberts, Rui Zhang, Juan J de Pablo
Liquid crystal shells have attracted considerable attention in recent years. In such systems, a combination of confinement and curvature generates topological defect structures that do not exist in the bulk. Past studies, however, have largely focused on perfectly spherical shells, and little attention has been devoted to the impact of core geometry on the configuration and arrangement of topological defects. In this work, a microfluidic glass capillary device is used to encapsulate spherical and prolate ellipsoidal particles in nematic liquid crystal (LC) droplets dispersed in aqueous media...
October 17, 2017: Soft Matter
https://www.readbyqxmd.com/read/29038599/widespread-white-matter-microstructural-differences-in-schizophrenia-across-4322-individuals-results-from-the-enigma-schizophrenia-dti-working-group
#10
S Kelly, N Jahanshad, A Zalesky, P Kochunov, I Agartz, C Alloza, O A Andreassen, C Arango, N Banaj, S Bouix, C A Bousman, R M Brouwer, J Bruggemann, J Bustillo, W Cahn, V Calhoun, D Cannon, V Carr, S Catts, J Chen, J-X Chen, X Chen, C Chiapponi, Kl K Cho, V Ciullo, A S Corvin, B Crespo-Facorro, V Cropley, P De Rossi, C M Diaz-Caneja, E W Dickie, S Ehrlich, F-M Fan, J Faskowitz, H Fatouros-Bergman, L Flyckt, J M Ford, J-P Fouche, M Fukunaga, M Gill, D C Glahn, R Gollub, E D Goudzwaard, H Guo, R E Gur, R C Gur, T P Gurholt, R Hashimoto, S N Hatton, F A Henskens, D P Hibar, I B Hickie, L E Hong, J Horacek, F M Howells, H E Hulshoff Pol, C L Hyde, D Isaev, A Jablensky, P R Jansen, J Janssen, E G Jönsson, L A Jung, R S Kahn, Z Kikinis, K Liu, P Klauser, C Knöchel, M Kubicki, J Lagopoulos, C Langen, S Lawrie, R K Lenroot, K O Lim, C Lopez-Jaramillo, A Lyall, V Magnotta, R C W Mandl, D H Mathalon, R W McCarley, S McCarthy-Jones, C McDonald, S McEwen, A McIntosh, T Melicher, R I Mesholam-Gately, P T Michie, B Mowry, B A Mueller, D T Newell, P O'Donnell, V Oertel-Knöchel, L Oestreich, S A Paciga, C Pantelis, O Pasternak, G Pearlson, G R Pellicano, A Pereira, J Pineda Zapata, F Piras, S G Potkin, A Preda, P E Rasser, D R Roalf, R Roiz, A Roos, D Rotenberg, T D Satterthwaite, P Savadjiev, U Schall, R J Scott, M L Seal, L J Seidman, C Shannon Weickert, C D Whelan, M E Shenton, J S Kwon, G Spalletta, F Spaniel, E Sprooten, M Stäblein, D J Stein, S Sundram, Y Tan, S Tan, S Tang, H S Temmingh, L T Westlye, S Tønnesen, D Tordesillas-Gutierrez, N T Doan, J Vaidya, N E M van Haren, C D Vargas, D Vecchio, D Velakoulis, A Voineskos, J Q Voyvodic, Z Wang, P Wan, D Wei, T W Weickert, H Whalley, T White, T J Whitford, J D Wojcik, H Xiang, Z Xie, H Yamamori, F Yang, N Yao, G Zhang, J Zhao, T G M van Erp, J Turner, P M Thompson, G Donohoe
The regional distribution of white matter (WM) abnormalities in schizophrenia remains poorly understood, and reported disease effects on the brain vary widely between studies. In an effort to identify commonalities across studies, we perform what we believe is the first ever large-scale coordinated study of WM microstructural differences in schizophrenia. Our analysis consisted of 2359 healthy controls and 1963 schizophrenia patients from 29 independent international studies; we harmonized the processing and statistical analyses of diffusion tensor imaging (DTI) data across sites and meta-analyzed effects across studies...
October 17, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/29038434/barley-six-rowed-spike3-encodes-a-putative-jumonji-c-type-h3k9me2-me3-demethylase-that-represses-lateral-spikelet-fertility
#11
Hazel Bull, M Cristina Casao, Monika Zwirek, Andrew J Flavell, William T B Thomas, Wenbin Guo, Runxuan Zhang, Paulo Rapazote-Flores, Stylianos Kyriakidis, Joanne Russell, Arnis Druka, Sarah M McKim, Robbie Waugh
The barley inflorescence (spike) comprises a multi-noded central stalk (rachis) with tri-partite clusters of uni-floretted spikelets attached alternately along its length. Relative fertility of lateral spikelets within each cluster leads to spikes with two or six rows of grain, or an intermediate morphology. Understanding the mechanisms controlling this key developmental step could provide novel solutions to enhanced grain yield. Classical genetic studies identified five major SIX-ROWED SPIKE (VRS) genes, with four now known to encode transcription factors...
October 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/29037390/effect-of-feeding-rumen-protected-capsule-containing-niacin-k2so4-vitamin-c-and-gamma-aminobutyric-acid-on-heat-stress-and-performance-of-dairy-cows
#12
W J Guo, L Zhen, J X Zhang, S Lian, H F Si, J R Guo, H M Yang
This study was conducted to evaluate the effects of supplemental rumen-protected capsule (RPC) on animal performance, serological indicators, and serum heat shock protein 70 (HSP70) of lactating Holstein cows under heat stress (HS). During summer months, 30 healthy multiparous lactating Holstein cows with a parity number of 3.1 ± 0.44, 70 ± 15 d in milk, an average body weight of 622 ± 62kg, and an average milk yield of 32.28 ± 0.96kg/d, were used. The cows were randomly allocated to two groups: a control group and an RPC-supplemented group (0...
October 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/29036997/-mean-blood-pressure-among-the-adults-in-china-2010-2012-based-on-the-results-of-mercury-sphygmomanometer-and-converted-electronic-sphygmomanometer
#13
D M Yu, P Fu, W T Yu, H J Guo, X G Yang, W H Zhao, L Y Zhao
Objective: To analyze the average systolic blood pressure (SBP) and diastolic blood pressure (DBP) among adults aged 18 years old and above in China between 2010 and 2012; and to compare the difference in the results measured by mercury sphygmomanometer and converted electronic sphygmomanometer. Methods: The data was collected from Chinese Nutrition and Health Surveillance in 2010-2012. 120 428 adults aged 18 years old and above were selected from 150 survey counties (districts) of 31 provinces in China Mainland, by multi-stage stratified and probability proportion to size (PPS) cluster randomization sampling method...
October 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29036981/-a-case-of-takotsubo-syndrome
#14
X Y Gao, C Y Guo, J G Yang
No abstract text is available yet for this article.
September 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29036962/-cladribine-in-the-treatment-of-tet2-refractory-acute-myeloid-leukemia-a-case-report
#15
J Liu, R Guo, Z X Jiang
No abstract text is available yet for this article.
October 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29036959/-the-study-of-liver-macrophages-polarization-in-patients-with-autoimmune-hepatitis
#16
L P Guo, L Zhou, H X Li, J Zhang, B M Wang
To explore the functional phenotype of liver macrophages in patients with autoimmune hepatitis (AIH). Compared with patients with nonalcoholic fatty liver disease (NAFLD) and chronic hepatitis B (CHB), the absolute CD(68)(+) cell count in patients with AIH was significantly higher (all P<0.05). It was positively correlated with ALT and IgG levels (the correlation coefficients 0.600 and 0.700, P=0.285 and 0.188 respectively). Additionally, compared with patients with NAFLD, the absolute iNOS positive cell count in patients with AIH and CHB were significantly higher (all P<0...
October 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/29036669/comparative-genome-and-transcriptome-analyses-reveal-adaptations-to-opportunistic-infections-in-woody-plant-degrading-pathogens-of-botryosphaeriaceae
#17
Ji Ye Yan, Wen Sheng Zhao, Zhen Chen, Qi Kai Xing, Wei Zhang, K W Thilini Chethana, Min Feng Xue, Jian Ping Xu, Alan J L Phillips, Yong Wang, Jian Hua Liu, Mei Liu, Ying Zhou, Ruvishika S Jayawardena, Ishara S Manawasinghe, Jin Bao Huang, Guang Hang Qiao, Chun Yuan Fu, Fei Fei Guo, Asha J Dissanayake, You Liang Peng, Kevin D Hyde, Xing Hong Li
Botryosphaeriaceae are an important fungal family that cause woody plant diseases worldwide. Recent studies have established a correlation between environmental factors and disease expression; however, less is known about factors that trigger these diseases. The current study reports on the 43.3 Mb de novo genome of Lasiodiplodia theobromae and five other genomes of Botryosphaeriaceae pathogens. Botryosphaeriaceous genomes showed an expansion of gene families associated with cell wall degradation, nutrient uptake, secondary metabolism and membrane transport, which contribute to adaptations for wood degradation...
October 3, 2017: DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
https://www.readbyqxmd.com/read/29035052/filling-the-missing-links-of-m3n-prototype-3d-4f-and-4f-cyclic-coordination-cages-syntheses-structures-and-magnetic-properties-of-the-ni10ln5-and-the-er3n-wheels
#18
Guo-Jun Zhou, Wei-Peng Chen, Youzhu Yu, Lei Qin, Tian Han, Yan-Zhen Zheng
In this paper, we proposed a number rule for 3d-4f and 4f cyclic coordination cages (CCCs); that is, CCCs consisting of vertex-sharing M4(μ3-OH)4 (M = 3d transition metal or 4f lanthanide ions) units should have 3 × n metal centers (abbreviated M3n), where n represents the number of the M4(μ3-OH)4 subunits. Under this number rule we reasoned that some species of CCCs, for example, the pentadecanuclear 3d-4f wheel and the pure 4f wheels with 9 or 18 centers, should practically have existed. However, there are no such complexes reported in the literature...
October 16, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/29034365/ethnicity-sex-and-age-are-determinants-of-red-blood-cell-storage-and-stress-hemolysis-results-of-the-reds-iii-rbc-omics-study
#19
Tamir Kanias, Marion C Lanteri, Grier P Page, Yuelong Guo, Stacy M Endres, Mars Stone, Sheila Keating, Alan E Mast, Ritchard G Cable, Darrell J Triulzi, Joseph E Kiss, Edward L Murphy, Steve Kleinman, Michael P Busch, Mark T Gladwin
Genetic polymorphisms in blood donors may contribute to donor-specific differences in the survival of red blood cells (RBCs) during cold storage and after transfusion. Genetic variability is anticipated to be high in donors with racial admixture from malaria endemic regions such as Africa and Asia. The purpose of this study was to test the hypothesis that donor genetic background, reflected by sex and self-reported ethnicity, significantly modulates RBC phenotypes in storage. High throughput hemolysis assays were developed and used to evaluate stored RBC samples from 11 115 African American, Asian, white, and Hispanic blood donors from 4 geographically diverse regions in the United States...
June 27, 2017: Blood Advances
https://www.readbyqxmd.com/read/29032636/tokyo-guidelines-2018-diagnostic-criteria-and-severity-grading-of-acute-cholecystitis-with-videos
#20
Masamichi Yokoe, Jiro Hata, Tadahiro Takada, Steven M Strasberg, Horacio J Asbun, Go Wakabayashi, Kazuto Kosaka, Itaru Endo, Daniel J Deziel, Fumihiko Miura, Kohji Okamoto, Tsann-Long Hwang, Wayne Shih-Wei Huang, Chen-Guo Ker, Miin-Fu Chen, Ho-Seong Han, Yoo-Seok Yoon, In-Seok Choi, Dong-Sup Yoon, Yoshinori Noguchi, Satoru Shikata, Tomohiko Ukai, Ryota Higuchi, Toshifumi Gabata, Yasuhisa Mori, Yukio Iwashita, Taizo Hibi, Palepu Jagannath, Eduard Jonas, Kui-Hin Liau, Christos Dervenis, Dirk Joan Gouma, Daniel Cherqui, Giulio Belli, O James Garden, Mariano Eduardo Giménez, Eduardo de Santibañes, Kenji Suzuki, Akiko Umezawa, Avinash Nivritti Supe, Henry A Pitt, Harjit Singh, Angus C W Chan, Wan Yee Lau, Anthony Yuen Bun Teoh, Goro Honda, Atsushi Sugioka, Koji Asai, Harumi Gomi, Takao Itoi, Seiki Kiriyama, Masahiro Yoshida, Toshihiko Mayumi, Naoki Matsumura, Hiromi Tokumura, Seigo Kitano, Koichi Hirata, Kazuo Inui, Yoshinobu Sumiyama, Masakazu Yamamoto
TG13 Tokyo guidelines for acute cholangitis and cholecystitis were globally disseminated and various clinical researches about the management of acute cholecystitis were reported by lots of researchers and clinicians from all over the world. The 1(st) edition of Tokyo Guidelines 2007 (TG07) was revised in 2013. According to that revision, the TG13 diagnostic criteria of acute cholecystitis provided better specificity and higher diagnostic accuracy. Thorough our literature search about diagnostic criteria for acute cholecystitis, new and strong evidence that had been released from 2013 to 2017 was not found with serious and important issues about using TG13 diagnostic criteria of acute cholecystitis...
October 15, 2017: Journal of Hepato-biliary-pancreatic Sciences
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