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https://www.readbyqxmd.com/read/29670784/ultrasound-presentation-of-a-disseminated-fetal-and-neonatal-rhabdoid-tumor
#1
Yolaine Joueidi, Aline Rousselin, Céline Rozel, Philippe Loget, Dominique Ranchere Vince, Sylvie Odent, Franck Bourdeaut, Vincent Lavoue, Maela Le Lous
This is a case report of a disseminated fetal rhabdoid tumor discovered at 32 weeks of gestation in a 29-year-old woman on immunosuppressive therapy. The mother consulted for a decrease in fetal movement. Fetal ultrasound showed signs of a disseminated tumor affecting the left armpit, liver, spleen, and limbs. A caesarian section was performed because of signs of fetal distress. Immunohistochemical analysis of a fetal biopsy showed deletion of the SMARCB1 gene. Pathological analysis of the placenta showed a rhabdoid tumor invading both fetal and maternal compartments...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29660063/five-successful-pregnancies-with-antenatal-anakinra-exposure
#2
Chelsey J F Smith, Christina D Chambers
Objectives: Our aim is to add to the limited existing prospective data on IL-1 inhibitor use in pregnancy. Methods: Data were obtained from the Organization of Teratology Information Specialists Autoimmune Disease in Pregnancy Project, a prospective cohort study of pregnancy outcomes in the USA and Canada. Eligible women were enrolled prior to 19 weeks' gestation between 2004 and 2017. Outcomes were obtained by maternal interview and medical record abstraction. Results: Five pregnancies with anakinra exposure were identified, all resulting in full-term singleton live births with no major or long-term complications...
April 12, 2018: Rheumatology
https://www.readbyqxmd.com/read/29619495/fournier-s-gangrene-in-an-obese-female-in-third-trimester-of-pregnancy
#3
Saqer Althunayyan, Evangelos Karamitosos
Fournier gangrene is a rapidly progressive necrotizing fasciitis of the perianal and genitourinary area. Although typically affects men, we present here a rare disease founding in a pregnant woman. An obese 36-year-old female patient in her third trimester of pregnancy presented with a history of perianal pain and swelling. She was subsequently diagnosed with Fournier gangrene and underwent emergency cesarean section with a surgical debridement. The key to successful outcomes in such a complicated presentation of Fournier gangrene includes a high index of suspicion, fluid resuscitation, rapid administration of broad-spectrum antibiotics, and an early interdisciplinary approach by multiple teams...
April 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29618226/the-effect-of-rectus-muscle-re-approximation-at-cesarean-delivery-on-pain-perceived-after-operation-a-randomized-control-trial
#4
Eman F Omran, Hadeer Meshaal, Sarah M Hassan, Amira S Dieb, Hala Nabil, Hani Saad
BACKGROUND: Cesarean section rate has increased dramatically worldwide but there is still debate about the optimum operative technique of cesarean section. OBJECTIVE: The purpose of this study was to assess the effect of rectus muscle reapproximation at cesarean delivery on the postoperative pain. METHODS: This study was a prospective, double-blind, randomized controlled trial. It included 280 primigravidas, with a singleton pregnancy, who underwent elective lower segment cesarean section at term...
April 4, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29580927/acrylamide-applied-during-pregnancy-causes-the-neurotoxic-effect-by-lowering-bdnf-levels-in-the-fetal-brain
#5
Mehmet Erman Erdemli, M Arif Aladag, Eyup Altinoz, Sezin Demirtas, Yusuf Turkoz, Birgül Yigitcan, Harika Gozukara Bag
OBJECTIVES: The aim of this study is to elucidate the possible mechanism of neurotoxic effect of acrylamide (AA) applied during pregnancy on fetal brain development and to show the effect of N-acetylcysteine (NAC) on AA toxicity. MATERIALS AND METHODS: Four groups were formed with 9 pregnant rats each as control (C), acrylamide (AA), N-acetylcysteine (NAC), acrylamide plus N-acetylcysteine (AA plus NAC) groups. Caesarian section was implemented on the 20th day of pregnancy...
March 23, 2018: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/29568657/use-of-extracorporeal-membrane-oxygenation-in-postpartum-management-of-a-patient-with-pulmonary-arterial-hypertension
#6
Humna Abid Memon, Zeenat Safdar, Ahmad Goodarzi
Current guidelines do not recommend pregnancy in patients with pulmonary arterial hypertension (PAH). This is due to the associated high mortality, which both dissuades PAH patients from becoming pregnant and encourages termination of pregnancy due to high maternal mortality risk. As a result, there is a lack of data and, consequently, there are only general guidelines available for management of pregnancy in PAH patients. Additionally, novel therapeutic strategies such as extracorporeal membrane oxygenation (ECMO), although used in the management of nonpregnant PAH patients as a bridge to lung transplantation, have not been used to treat cardiopulmonary collapse in pregnant PAH patients...
2018: Case Reports in Pulmonology
https://www.readbyqxmd.com/read/29554014/impaired-trunk-flexor-strength-fatigability-and-steadiness-in-postpartum-women
#7
Rita E Deering, Meredith Cruz, Jonathon W Senefeld, Tatyana Pashibin, Sarah Eickmeyer, Sandra K Hunter
PURPOSE: To determine whether postpartum women (vaginal and Cesarean delivery) have deficits in trunk flexor strength, fatigability and steadiness, compared with nulligravid women, up to 26 weeks postpartum. We hypothesized that postpartum women would be weaker, more fatigable and have greater torque fluctuations than controls, with Cesarean delivery showing greater deficits than vaginal delivery. METHODS: 22 control women (nulligravid) and 29 postpartum women (20-40 years, 19 who delivered via vaginal birth, 13 via Caesarian section) participated...
March 16, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29545986/skin-endometriosis-at-the-caesarean-section-scar-a-case-report-and-review-of-the-literature
#8
Fatimah Alnafisah, Shaimaa K Dawa, Sherif Alalfy
Cutaneous endometriosis is one of the rare gynecological conditions. Endometriosis is defined as the presence of endometrial glands and stroma outside the endometrial cavity. It commonly occurs in pelvic sites, such as the ovaries, cul-de-sac, bowel, or pelvic peritoneum. Endometriosis at the incisional scar is difficult to diagnose because of nonspecific symptoms. Usually, patients complain of pain at the site of the incision during menstruation. The main causes in most of the reported cases are obstetrical and gynecological surgeries...
January 13, 2018: Curēus
https://www.readbyqxmd.com/read/29495225/-effects-of-prenatal-tetrandrine-treatment-on-the-expression-of-kruppel-like-factor-5-and-survivin-in-the-lung-of-congenital-diaphragmatic-hernia-rat-model-induced-by-nitrofen
#9
Q Jiang, W Y Liu, W Feng, H H Jia, F Hou
Objective: To investigate the effect of prenatal administration of tetrandrine on the expression of Kruppel-like factors 5 (KLF5) and Survivin in the lung of congenital diaphragmatic hernia (CDH) rat model. Methods: This experiment took simple random group method, 11 pregnant SD rats were randomly divided into three groups: normal control group (group NC, 3), model control group (group MC, 4), model+ tetrandrine group (group MT, 4). The rats in group MC and MT were given gavage administration with 125 mg nitrofen to induce CDH and the rats in group MT were administered with 30 mg/kg tetrandrine for three days (gestational age of 18...
February 13, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29459586/risk-factors-and-immediate-neonatal-outcome-of-multiple-pregnancies-in-a-scanu-of-a-tertiary-care-hospital-bangladesh
#10
M N Islam, T Tazmin, M Siddika, M A Hossain, M A Ali, M K Bhuiyan
Multiple pregnancies are a significant risk factor for maternal and perinatal morbidity due to inherent biological risks. The present study was aimed to determine the risk factors and to evaluate the immediate neonatal outcome of multiple pregnancies. This descriptive observational study was conducted in the newly established Special Care Neonatal Unit (SCANU) of Mymensingh Medical College Hospital (MMCH), Bangladesh from January 2015 to March 2015. Total 86 newborns of multiple pregnancies who were admitted during the study period were included in the study...
January 2018: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29423189/early-neonatal-mortality-in-twin-pregnancy-findings-from-60-low-and-middle-income-countries
#11
Saverio Bellizzi, Howard Sobel, Ana Pilar Betran, Marleen Temmerman
Background: Around the world, the incidence of multiple pregnancies reaches its peak in the Central African countries and often represents an increased risk of death for women and children because of higher rates of obstetrical complications and poor management skills in those countries. We sought to assess the association between twins and early neonatal mortality compared with singleton pregnancies. We also assessed the role of skilled birth attendant and mode of delivery on early neonatal mortality in twin pregnancies...
June 2018: Journal of Global Health
https://www.readbyqxmd.com/read/29411210/down-regulation-of-itga4-and-itga5-genes-after-formation-of-3d-spherules-by-human-wharton-s-jelly-stem-cells-hwjscs
#12
Zohreh Mostafavi-Pour, Mohammad Reza Ashrafi, Tahereh Talaei-Khozani
Human Wharton's jelly mesenchymal stem cells (hWJSCs) are multipotent stem cells that could be aggregated into 3D spherules. ITGA4 and ITGA5 genes encode α4 and α5 subunits of integrins, respectively. In this study, we analyzed expression levels of ITGA4 and ITGA5 gene mRNAs in undifferentiated and 3D spherules forming hWJSCs in order to determine their expression pattern for possible future treatment of cancer cells in a co-culture fashion. For the purpose of obtaining hWJSCs, umbilical cords were collected from patients with caesarian section at full term delivery...
February 6, 2018: Molecular Biology Reports
https://www.readbyqxmd.com/read/29302262/does-anaesthesia-in-mothers-during-delivery-affect-bilirubin-levels-in-their-neonates
#13
Zeinab A El-Kabbany, Nadin N Toaima, Tamer N Toaima, Mona Y Gamal El-Din
Purpose: This study aimed to assess whether different anesthetic techniques and oxytocin use applied during delivery affect transcutaneous bilirubin levels during the first 24 hours in neonates. Methods: A total of 1,044 neonates delivered by either caesarian section (C/S) or normal vaginal delivery (NVD) were included in the study. They were classified into 5 groups as follows: group 1: born by C/S using general anesthesia, group 2: C/S using spinal anaesthesia, group 3: C/S using general anesthesia after failed spinal block, group 4: by NVD without anesthesia, and group 5: oxytocin-induced vaginal delivery without anesthesia...
December 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29298686/a-single-center-experience-with-12-consecutive-cases-of-pregnancy-among-patients-with-membranous-ventricular-septal-aneurysm
#14
Kana Wang, Xiaodong Wang, Haiyan Yu, Xinghui Liu, Aiyun Xing, Yong You
BACKGROUND: Membranous ventricular septal aneurysm (MVSA) is a rare cardiac anomaly that can occur as an isolated entity or being associated with other cardiac malformations. Complications of MVSA include thromboembolism, arrhythmia, rupture, bacterial endocarditis, right ventricular outflow tract obstruction, and atrioventricular valve diseases.The success rate of pregnancy and delivery in patients with MVSA has not been reported in the literature. This study was to assess the clinical implications of this condition from our center's experience...
January 3, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29288840/morganella-as-a-cause-of-ophthalmia-neonatorum
#15
Michael F Ward, Daniel J Olson, Michael Taggart, Sara F Grace
A 2 day-old-girl with a complicated birth history, including prolonged rupture of membranes and Caesarian section delivery, presented with a purulent bacterial conjunctivitis of the left eye despite standard prophylaxis. Bacterial cultures yielded 1+ Morganella morganii, a facultative anaerobe and a rare cause of ocular pathology. The patient was treated with topical tobramycin four times daily for 7 days, resulting in resolution of her conjunctivitis.
February 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29216607/frequency-of-risk-factors-and-coexisting-abnormalities-in-a-population-of-egyptian-children-with-autism-spectrum-disorder
#16
Nagwa Abdel Meguid, Neveen Hassan Nashaat, Heba S Hashem, Mai M Khalil
BACKGROUND: Many risk factors interact together during the critical period of development and govern the future phenotype of autism spectrum disorder (ASD). Furthermore, co-occurring abnormalities among individuals with ASD vary a lot so as their abilities. AIM OF WORK: To investigate possible risk factors and to determine the prevalence of coexisting abnormalities in a sample of Egyptian ASD children and their influence on the severity and their communication performance...
February 2018: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29187254/acute-disseminated-melioidosis-giving-rise-to-pneumonia-and-renal-abscesses-complicated-with-thrombotic-thrombocytopenic-purpura-in-a-post-partum-woman-a-case-report
#17
Piyumi Sachindra Alwis Wijewickrama, Rohini Weerakoon
BACKGROUND: Melioidosis is an established endemic infection in Sri Lanka, caused by Burkholderia pseudomallei, a gram negative bacterium distributed in saprophytes in soil and surface water. Main mode of transmission is via percutaneous inoculation. Pneumonia is the most common presentation in acute disease. CASE PRESENTATION: We report a 33 year old previously healthy Sinhalese female with an occupational exposure to surface water in paddy fields, who was on postpartum day 6 following an uncomplicated pregnancy and delivery via an elective caesarian section...
November 29, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29151790/surgical-scar-endometriosis-a-series-of-14-patients-and-brief-review-of-literature
#18
Andrei Mihai Malutan, Ioan Simon, Razvan Ciortea, Radu Florin Mocan-Hognogi, Marina Dudea, Dan Mihu
Background and aims: Endometriosis is a commonly encountered disorder in women of reproductive age, consisting of the presence of active ectopic endometrial tissue outside the endometrial cavity. Surgical scar endometriosis is a rare condition representing about 2% of all endometriosis cases. The purpose of this study was to assess the main characteristics, diagnostic tools and therapeutic options in abdominal wall endometriosis (AWE). Methods: We have reviewed a series of fourteen cases with histopathological confirmation of AWE that were managed in our institution...
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29148636/outcome-of-pregnancy-with-clinically-visible-palpable-myoma-among-women-who-undergo-caesarian-section-in-three-teaching-hospitals-addis-ababa-ethiopia-a-cross-sectional-study
#19
Getu Dinku, Eyasu Mesfin
Introduction: Myoma is the most common pelvic tumor and an enormous healthcare concern in women. Complications occur in approximately 10-40% of pregnancies with myomatous uterus. This study is conducted to determine the prevalence and obstetric outcome of grossly visible and/or palpable myoma among women who gave birth by caesarean section. Methods: A cross sectional study conducted in three teaching hospitals in Addis Ababa, Ethiopia. Data was collected using a pre-tested questioner...
January 2017: Ethiopian Medical Journal
https://www.readbyqxmd.com/read/29091782/ante-peri-and-postnatal-factors-associated-with-intraventricular-hemorrhage-in-very-premature-infants
#20
Martin Poryo, Judith Caroline Boeckh, Ludwig Gortner, Michael Zemlin, Perrine Duppré, Daniel Ebrahimi-Fakhari, Stefan Wagenpfeil, Matthias Heckmann, Eva Mildenberger, Anne Hilgendorff, Andreas W Flemmer, Georg Frey, Sascha Meyer
BACKGROUND: Intraventricular hemorrhage (IVH) is one of the most serious complications in preterm infants and is associated with neurological sequelae and mortality. Over the past few decades, the rate of IVH has decreased due to improved neonatal intensive care. However, up to 15-25% of very and extremely premature infants (<32 and <28weeks of pregnancy (WOP) respectively) still suffer from IVH. STUDY PURPOSE: The aim of this study was to perform an updated, multicenter analysis to identify ante-, peri, and postnatal factors other than gestational age/birth weight associated with IVH of any grade in a large cohort of very and extremely premature infants...
January 2018: Early Human Development
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