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Left main coronary artery

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https://www.readbyqxmd.com/read/28640875/percutaneous-coronary-intervention-in-left-main-coronary-artery-disease-with-or-without-intravascular-ultrasound-a-meta-analysis
#1
Yicong Ye, Ming Yang, Shuyang Zhang, Yong Zeng
This meta-analysis compared IVUS-guided with angiography-guided PCI to determine the effect of IVUS on the mortality in patients with LM CAD. Current guidelines recommend intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) in patients with left main coronary artery disease (LM CAD; Class IIa, level of evidence B). A systematic search of the MEDLINE, Embase, and Cochrane Central Register of Controlled Trials databases was conducted to identify randomized or non-randomized studies comparing IVUS-guided PCI with angiography-guided PCI in LM CAD...
2017: PloS One
https://www.readbyqxmd.com/read/28636634/cardiomyopathy-development-protection-after-myocardial-infarction-in-rats-successful-competition-for-major-dihydropyridines-common-metabolite-against-captopril
#2
Katarzyna A Mitręga, Adrianna M Spałek, Jerzy Nożyński, Maurycy Porc, Magdalena Stankiewicz, Tadeusz F Krzemiński
During the last 25 years angiotensin-converting enzyme inhibitors spectacularly conquered the field of cardiovascular diseases therapy. Nevertheless, lack of new studies concerning side effects associated with their chronic administration seems to be rather confusing. In our previous research, we proved that the main furnidipines' metabolite (M-2) possess multiple cardioprotective actions. Currently, we compared effects of post-infarction long-term oral treatment with M-2 and captopril on hemodynamic parameters and "ischemic cardiomyopathy" development in rats...
2017: PloS One
https://www.readbyqxmd.com/read/28635247/spontaneous-coronary-dissection-of-left-anterior-descending-artery-complicated-by-retrograde-extension-of-dissection-and-involvement-of-left-main-artery-successful-management-with-percutaneous-coronary-intervention
#3
Nirmal Guragai, Hiten Patel, Kunal Patel, Adelaide Viguri, Fayez Shamoon, Emile Doss
No abstract text is available yet for this article.
August 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/28633398/a-novel-system-for-the-treatment-of-aortic-annular-dilation-an-ex-vivo-investigation
#4
Pallav Shah, Claudia Romagnoni, Michal Jaworek, Federico Lucherini, Monica Contino, Alan Menkis, Guido Gelpi, Gianfranco B Fiore, Carlo Antona, Riccardo Vismara
OBJECTIVES: The main reason for aortic repair failures is recurrent annular dilatation. The fibrous portion of left ventricular outflow tract dilates. A novel device was designed to tackle this problem. METHODS: The device consists of an internal ring applied at the aortic annulus plus an external flexible band at the level of the aortic root. The internal ring has a semi-rigid portion (40%, placed at ventriculo-arterial junction) and a flexible portion to allow it to conform along the curves of the non-coronary/right coronary leaflet and right coronary/left coronary leaflet commissures...
June 15, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28633263/structural-valve-deterioration-of-a-subcoronary-implanted-stentless-bioprosthesis-how-to-treat
#5
Eva Karolina Harmel, Lenard Conradi, Ulrich Schäfer, Florian Deuschl, Niklas Schofer, Stefan Blankenberg, Hermann Reichenspurner, Evaldas Girdauskas
We present a case of transcatheter valve-in-valve replacement performed because of structural valve deterioration of a subcoronary implanted stentless aortic bioprosthesis. A 23-mm self-expandable transcatheter heart valve (THV) with supraannular seating was chosen. The procedure was performed with the patient under conscious sedation. After anchoring and partial valve deployment, the patient experienced an acute onset of angina. The angiogram showed left main coronary artery obstruction. Prompt resheathing and retrieval of the THV was performed, and the procedure was aborted...
July 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28632734/choroidal-thickness-in-patients-with-coronary-artery-disease
#6
Meleha Ahmad, Patrick A Kaszubski, Lucy Cobbs, Harmony Reynolds, Roland Theodore Smith
PURPOSE: To evaluate choroidal thickness (CTh) in patients with coronary artery disease (CAD) compared to healthy controls. DESIGN: Cross-sectional. METHODS: Setting: Ambulatory clinic of a large city hospital. Patient population: Thirty-four patients had documented CAD, defined as history of >50% obstruction in at least one coronary artery on cardiac catheterization, positive stress test, ST elevation myocardial infarction, or revascularization procedure...
2017: PloS One
https://www.readbyqxmd.com/read/28616538/aorto-ostial-atherosclerotic-coronary-artery-disease-risk-factor-profiles-demographic-angiographic-features
#7
S K Verma, B Kumar, V K Bahl
BACKGROUND: The risk factors along with demographic and angiographic features associated with aorto-ostial atherosclerotic coronary artery disease usually differ from that of non-aorto-ostial atherosclerotic coronary artery disease. OBJECTIVES: This study was designed to evaluate etiology of aorto-ostial atherosclerotic coronary artery disease involving left main coronary artery (LMCA), right coronary artery or both with consideration of clinical risk factors, demographic and angiographic features...
September 2016: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/28616307/pci-or-cabg-for-severe-unprotected-left-main-coronary-artery-disease-making-sense-of-the-noble-and-excel-trials
#8
EDITORIAL
Anthony A Holmes, Sripal Bangalore
No abstract text is available yet for this article.
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28616264/optimal-revascularization-for-left-main-coronary-artery-disease-coronary-artery-bypass-grafting-versus-percutaneous-coronary-intervention
#9
EDITORIAL
Ian C Bostock, Jock N McCullough, Alexander Iribarne
No abstract text is available yet for this article.
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28614263/misdiagnosed-anomalous-left-coronary-artery-from-the-pulmonary-artery-as-endocardial-fibroelastosis-in-infancy-a-case-series
#10
Fan Ma, Kaiyu Zhou, Xiaoqing Shi, Xiaoqing Wang, Yi Zhang, Yifei Li, Yimin Hua, Chuan Wang
INTRODUCTION: Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare but severe congenital cardiac malformation. The prognosis mainly depends on the early and accurate diagnosis and treatment. However, without a typical and specific clinical manifestation in early stage, ALCAPA has a higher rate of false initial diagnosis. DIAGNOSTIC AND THERAPEUTIC PROCEDURE: Three infants with impaired left ventricle (LV) function, LV enlargement, mitral valve regurgitation (MR), and LV endocardium thickness were initially diagnosed as endocardial fibroelastosis (EFE)...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28613933/quantification-of-radiation-dose-reduction-by-reducing-z-axis-coverage-in-320-detector-coronary-ct-angiography
#11
D J Murphy, A Keraliya, N Himes, A Aghayev, R Blankstein, M L Steigner
OBJECTIVES: To quantify the radiation dose reduction achievable by minimizing z-axis coverage in 320-detector coronary computed tomography angiography (CCTA). METHODS: We retrospectively reviewed 130 CCTAs performed on 320-detector CT that offers up to 16cm z-axis coverage (adjustable in 2cm increments), allowing complete coverage of the heart in a single gantry rotation. For each CT we obtained the radiation dose (CTDIvol and DLP), measured the z-axis field of view and measured the craniocaudal cardiac size (distance from the left main coronary artery to the cardiac apex)...
June 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28607000/percutaneous-coronary-intervention-of-left-main-disease-pre-and-post-excel-evaluation-of-xience-everolimus-eluting-stent-versus-coronary-artery-bypass-surgery-for-effectiveness-of-left-main-revascularization-and-noble-nordic-baltic-british-left-main-revascularization
#12
Duk-Woo Park, Seung-Jung Park
For nearly half a century, coronary artery bypass grafting has been the standard treatment for patients with obstructive left main coronary artery (LMCA) disease. However, there has been considerable evolution in the field of percutaneous coronary intervention, and especially, percutaneous coronary intervention for LMCA disease has been rapidly expanded with adoption of drug-eluting stents. Some, but not all randomized trials, have shown that percutaneous coronary intervention with drug-eluting stents might be a suitable alternative for selected patients with LMCA disease instead of bypass surgery...
June 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28606883/physiological-assessment-of-left-main-coronary-artery-disease
#13
Bhavik N Modi, Tim P van de Hoef, Jan J Piek, Divaka Perera
The left main coronary artery (LMCA) is responsible for supplying the majority of the left ventricular myocardium. Visual estimation of stenosis severity on angiography has major limitations and methods to assess functional significance, such as Fractional Flow Reserve (FFR), have been shown to yield better outcomes but major trials examining the use of such physiological indices have excluded LMCA disease to date. Furthermore, LMCA disease commonly co-exists with downstream disease, which complicates interpretation of coronary physiological data...
June 13, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28606023/over-expansion-of-drug-eluting-stents-in-patients-with-left-main-coronary-artery-disease-an-in%C3%A2-vivo-study
#14
Yicong Ye, Hao Qian, Ming Yang, Xueqing Zhu, Tianpeng Gan, Shuyang Zhang, Yong Zeng
Objective We aimed to determine the capacity of drug-eluting stent (DES) over-expansion in left main coronary artery disease. Methods Left main interventions with the largest available DES platforms (4.0 mm) and post-dilation performed with large non-compliant balloons (≥ 4.5 mm) were included. Maximal stent diameter (mm) and area (mm(2)) were measured using post-intervention intravascular ultrasound (IVUS). Stent diameter and area were calculated with the balloon diameter and inflation pressure. The diameter and area expansion indices were defined as follows: maximal/calculated stent diameter and maximal/calculated stent area, respectively...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28605922/surgical-coronary-revascularization-on-pump-versus-off-pump-in-patients-with-stenosis-of-the-main-tree-of-the-left-coronary-artery-and-carotid-stenosis
#15
Edin Kabil, Bedrudin Banjanović, Emir Mujanović
OBJECTIVE: The aim of this study was to show perioperative complications of CABG procedure with and without cardiopulmonary bypass (CPB) in patients with combined coronary and carotid disease. PATIENTS AND METHODS: This retrospective survey included patients with left main stenosis greater than 50% and carotid stenosis over 50%, who had undergone CABG without carotid endarterectomy at the BH Heart Centre, from May 2009 to May 2014. The patients were divided into two groups according to the surgical method used...
May 2017: Acta Medica Academica
https://www.readbyqxmd.com/read/28604505/prognostic-value-of-clinical-echocardiographic-and-angiographic-indicators-in-patients-with-large-anterior-st-segment-elevation-myocardial-infarction-as-a-first-acute-coronary-event
#16
Cesare Baldi, Maria V Polito, Rodolfo Citro, Rosario Farina, Tiziana Attisano, Marco Mirra, Paolo Chiodini, Michele R Di Muro, Marco Di Maio, Francesco Vigorito, Renato De Vecchis, Eduardo Bossone, Federico Piscione, Pietro Giudice, Gennaro Galasso
BACKGROUND: The risk of death in patients affected by ST-elevation segment myocardial infarction (STEMI) is well known, but more data are required to define the in-hospital mortality in special subsets. We sought to assess the prognostic value of indicators in patients with large anterior STEMI as a first acute coronary event, undergoing percutaneous coronary intervention (PCI) and intra-aortic balloon pump (IABP). METHODS AND RESULTS: We evaluated 48 consecutive large anterior STEMI patients admitted as first acute coronary event, undergoing in acute phase both PCI and IABP...
June 9, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28603725/multi-vessel-giant-coronary-artery-aneurysm-in-an-elderly-female
#17
Rami N Khouzam, Jonathan D Gardner, Ritin Bomb, Anthony A Holden
Coronary artery aneurysm (CAA) is a rare anomaly. The right coronary artery is the most commonly affected, followed by the left circumflex (LCX), or the left anterior descending artery (LAD). Three-vessel disease or left main (LM) involvement is extremely rare. A giant coronary artery aneurysm (GCAA) has an extremely low incidence and refers to an aneurysm that is 20 mm or greater in size. Most CAAs occur as a consequence of atherosclerosis. Most patients with CAA are males, have three-vessel disease, and a history of myocardial infarction (MI)...
May 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28597214/-diagnosis-of-ischemia-and-revascularization-in-patients-with-ventricular-tachyarrhythmia
#18
REVIEW
Thomas Deneke, Carsten W Israel
Sustained ventricular tachyarrhythmia usually occurs on the basis of structural heart disease, particularly coronary heart disease (CAD). Although monomorphic ventricular tachycardia (VT) appears mainly in patients with CAD, it is typically not triggered by acute ischemia, in contrast to polymorphic VT or ventricular fibrillation (VF). To judge if VT is caused by acute ischemia is even more difficult in context with an elevated highly sensitive troponin T which is generally elevated in sustained VT because tachycardia in chronic stable coronary artery sclerosis causes a mismatch between increased oxygen demand and limited oxygen supply...
June 8, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/28595861/comparison-of-outcome-of-coronary-artery-bypass-grafting-versus-drug-eluting-stent-implantation-for-non-st-elevation-acute-coronary-syndrome
#19
Mineok Chang, Cheol Whan Lee, Jung-Min Ahn, Rafael Cavalcante, Yohei Sotomi, Yoshinobu Onuma, Minkyu Han, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Patrick W Serruys, Seung-Jung Park
There is limited data comparing effectiveness of coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI) with drug-eluting stents in patients with non-ST-elevation acute coronary syndromes (NSTE-ACS). We compared the long-term outcomes of the 2 revascularization strategies in 1,246 patients presented with NSTE-ACS for left main or multivessel coronary artery disease. Data were pooled from the Randomized Comparison of Coronary Artery Bypass Surgery and Everolimus-Eluting Stent Implantation in the Treatment of Patients with Multivessel Coronary Artery Disease (BEST) trial, the Premier of Randomized Comparison of Bypass Surgery versus Angioplasty Using Sirolimus-Eluting Stent in Patients with Left Main Coronary Artery Disease (PRECOMBAT) trial, and the Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) trial...
May 10, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28595697/left-main-coronary-artery-compression-in%C3%A2-patients-with-pulmonary-arterial-hypertension
#20
EDITORIAL
Fernando Alfonso, Fernando Rivero
No abstract text is available yet for this article.
June 13, 2017: Journal of the American College of Cardiology
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