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Left main coronary artery

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https://www.readbyqxmd.com/read/29447735/new-onset-atrial-fibrillation-after-pci-or-cabg-for-left-main-disease-the-excel-trial
#1
Ioanna Kosmidou, Shmuel Chen, A Pieter Kappetein, Patrick W Serruys, Bernard J Gersh, John D Puskas, David E Kandzari, David P Taggart, Marie-Claude Morice, Paweł E Buszman, Andrzej Bochenek, Erick Schampaert, Pierre Pagé, Joseph F Sabik, Thomas McAndrew, Björn Redfors, Ori Ben-Yehuda, Gregg W Stone
BACKGROUND: There is limited information on the incidence and prognostic impact of new-onset atrial fibrillation (NOAF) following percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for left main coronary artery disease (LMCAD). OBJECTIVES: This study sought to determine the incidence of NOAF following PCI and CABG for LMCAD and its effect on 3-year cardiovascular outcomes. METHODS: In the EXCEL (Evaluation of XIENCE Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization) trial, 1,905 patients with LMCAD and low or intermediate SYNTAX scores were randomized to PCI with everolimus-eluting stents versus CABG...
February 20, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29443766/meta-analysis-study-comparing-percutaneous-coronary-intervention-drug-eluting-stent-versus-coronary-artery-bypass-surgery-of-unprotected-left-main-coronary-artery-disease-clinical-outcomes-during-short-term-versus-long-term-1-year-follow-up
#2
Waleed E Ali, Satyanarayana R Vaidya, Sylvester U Ejeh, Kingsley U Okoroafor
BACKGROUND: Results on the safety and long-term efficacy of drug-eluting stent placement in unprotected left main coronary artery disease (ULMCAD) compared with those of coronary artery bypass surgery (CABG) remain inconsistent across randomized clinical trials and recent meta-analysis studies. We aimed to compare the clinical outcomes and safety over short- and long-term follow-ups by conducting a meta-analysis of large pooled data from randomized controlled trials and up-to-date observational studies...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29443740/clinical-outcomes-of-left-main-coronary-artery-disease-patients-undergoing-three-different-revascularization-approaches
#3
Chieh-Shou Su, Yu-Wei Chen, Ching-Hui Shen, Tsun-Jui Liu, Yen Chang, Wen-Lieng Lee
Significant unprotected left main (LM) coronary artery disease is frequently associated with severe multivessel disease and increased mortality and morbidity compared with non-LM coronary artery disease. This study compared the clinical outcomes of patients with LM disease who received percutaneous coronary intervention (PCI) with stenting, conventional coronary-artery bypass grafting (C-CABG), and robot-assisted CABG (R-CABG).This retrospective study analyzed 472 consecutive LM disease patients who underwent three different revascularization approaches at a tertiary medical center between January 2005 and November 2013...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29440624/aminophylline-for-preventing-bradyarrhythmias-during-orbital-or-rotational-atherectomy-of-the-right-coronary-artery
#4
Michael Megaly, Yader Sandoval, Matthew P Lillyblad, Emmanouil S Brilakis
BACKGROUND: Coronary atherectomy, orbital or rotational, is frequently used for plaque modification in patients with heavily calcified lesions. Atherectomy can be associated with clinically significant bradyarrhythmias or transient atrioventricular block requiring temporary pacemaker insertion, mainly in lesions involving the right coronary artery or a dominant left circumflex artery. Bradyarrhythmias may be mediated by endogenous release of adenosine from red blood cell breakdown. Aminophylline, an adenosine antagonist, can prevent adenosine-mediated bradyarrhythmias...
February 15, 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29439144/coronary-computed-tomography-angiography-detection-of-short-and-long-term-outcomes-after-heart-valve-surgery-with-high-risk-cardiovascular-patients
#5
Zhi Zhu, Shuofeng Li
Coronary computed tomography angiography (CCTA) is a promising alternative technique to detect significant coronary artery lesions in high-risk cardiovascular patients with left ventricular dysfunction (left ventricular ejection fractions < 40%) referred for elective valve surgery, while little research about the use of CCTA to detect the outcomes of heart valve surgery was performed. Forty-six consecutive high-risk cardiovascular patients with the New York Heart Association (NYHA) classification were retrospectively studied...
February 8, 2018: Bioscience Reports
https://www.readbyqxmd.com/read/29434132/usefulness-of-cutting-balloon-angioplasty-prior-to-stenting-with-intravascular-ultrasound-imaging-guidance-for-spontaneous-multi-vessel-coronary-dissection-including-the-left-main-coronary-artery
#6
Masahiko Noguchi, Kotaro Obunai, Yu Fukui, Hiroshi Okumura, Hiroyuki Watanabe
We report a case of percutaneous coronary intervention for spontaneous multi-vessel coronary dissection including the left main coronary artery. This case suggests that intracoronary imaging is useful for understanding the complex anatomy and for choosing the appropriate management for effective revascularization. Furthermore, cutting balloon angioplasty prior to stenting is useful for preventing the longitudinal extension of the intramural hematoma and avoiding unnecessary stent implantation.
February 9, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29430728/plasma-cxcl1-levels-and-traf3ip2-variants-in-patients-with-myocardial-infarction
#7
Safoora Pordel, Mahdi Sajedi Khanian, Mohammad Hossein Karimi, Hossein Nikoo, Mehrnoosh Doroudchi
BACKGROUND: IL-17A plays an important role in inflammatory responses in myocardial infarction (MI). IL-17A signals through its receptor, for which, Act1 (TRAF3IP2) functions as a key upstream adaptor in the pathway. AIM: To compare frequencies of functional polymorphisms of TRAF3IP2 (rs13210247, rs33980500) between patients with MI and healthy controls. METHODS: The selected SNPs were studied in 201 Iranian MI patients and 201 healthy blood donors from Fars Province by PCR-RFLP in association with clinicopathologic criteria of patients...
February 12, 2018: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29427620/arterioplasty-in-takayasu-s-arteritis-with-left-main-coronary-artery-involvement
#8
Haizhou Zhang, Xiaochun Ma, Qian Zhang, Qiqi Jiao, Chengwei Zou
Here we reported a case of a 24-year old female diagnosed as Takayasu's arteritis with left main coronary artery (LMCA) involvement in which we performed the arterioplasty of LMCA using glutaraldehyde-fixed autologous pericardial patch. Ten years of follow-up demonstrated the satisfactory patency of the ostium of LMCA.
February 7, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29411245/single-coronary-artery-anomaly-a-case-report-and-review-of-literature
#9
Ayman Elbadawi, Basarat Baig, Islam Y Elgendy, Erfan Alotaki, Ahmed H Mohamed, Kirolos Barssoum, David Fries, Muhammad Khan, Rami N Khouzam
INTRODUCTION: Single coronary artery is a rare anomaly, which is usually associated with other cardiac congenital abnormalities. CASE REPORT: A 56-year-old female presented with unstable angina. The patient reported complaints of typical chest pain on exertion few months prior to presentation, which progressed to become at rest. The pain was associated palpitations and dizziness. Past medical history was significant for hypertension and hyperlipidemia. Vital signs were stable...
February 6, 2018: Cardiology and Therapy
https://www.readbyqxmd.com/read/29408248/bilateral-opposing-loop-technique-b-o-l-t-for-securing-air-knots
#10
Laura M Seese, Faisal G Bakaeen, Ibrahim Sultan, Danny Chu
Incompletely seated knots (air knots) during surgical aortic valve replacement can be potentially difficult to repair in anatomically challenging areas around the aortic root. This is especially true with mechanical protheses as subvalvular areas are inaccessble once the valve is seated. In this report, we present a novel and simple technique of tightening air knots from within the aortic root without removing the prosthesis. The definitive surgical therapy for aortic valve disease has been in evolution since the advent of cardiopulmonary bypass and the development of aortic valve prostheses...
February 2, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29406046/effect-of-chronic-total-occlusion-percutaneous-coronary-intervention-on-clinical-outcomes-in-elderly-patients
#11
Hui-Ping Zhang, Hu Ai, Ying Zhao, Hui Li, Guo-Dong Tang, Nai-Xin Zheng, Fu-Cheng Sun, Jing-Hua Liu
BACKGROUND: There are little published data reporting the effect of coronary artery chronic total occlusion (CTO) percutaneous coronary intervention (PCI) on the prognosis of elderly patients with identified CTOs. We sought to evaluate the clinical effect of CTO PCI on the prognosis of elderly patients with CTOs. METHODS: A total of 445 consecutive patients diagnosed with a CTO by angiography from January 2011 to December 2013 were enrolled. We compared long-term clinical outcomes between the elderly group (≥75 years; n = 120, 27...
February 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29402709/spontaneous-dissection-of-the-left-main-coronary-artery-case-report-and-brief-review
#12
Manivannan Veerasamy, Mark E Jacoby, Ryan D Madder
No abstract text is available yet for this article.
December 23, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29402396/total-occlusion-of-the-left-main-coronary-artery-presenting-as-st-elevation-myocardial-infarction
#13
Yun-Tao Zhao, Hang Zhou, Ruiqi Shi, Bin Wang
An ECG pattern of widespread ST depression in six or more precordial and inferior leads, accompanied by ST-segment elevation in the aVR and/or V1 leads, is typical of the non-ST-segment elevation myocardial infarction (NSTEMI) pattern associated left main (LM) artery occlusion, but this ECG pattern is really associated with a subocclusion of the LM, or in the case that the LM was occluded with the presence of collateral circulation. There are few reports of ST-elevation myocardial infarction (STEMI) due to acute total LM occlusion...
February 2, 2018: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29400656/outcome-after-revascularisation-of-acute-myocardial-infarction-with-cardiogenic-shock-on-extracorporeal-life-support
#14
Pavel Overtchouk, Julien Pascal, Guillaume Lebreton, Jean-Sebastien Hulot, Charles-Edouard Luyt, Alain Combes, Mathieu Kerneis, Johanne Silvain, Olvier Barthelemy, Pascal Leprince, Nicolas Brechot, Gilles Montalescot, Jean-Philippe Collet
AIMS: To identify independent correlates of survival in patients undergoing PCI for refractory cardiogenic shock due to myocardial infarction (RCS-MI) with need for extracorporeal life support (ECLS). METHOD AND RESULTS: This observational single-tertiary-centre study enrolled 106 consecutive patients (52.7±10.4 years) with ECLS placed before or after the PCI. Half of the patients had triple vessel disease and PCI was attempted whenever possible (74.5%). The 30-day mortality rate was 63...
February 6, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29396239/long-term-outcomes-of-new-generation-drug-eluting-stents-versus-coronary-artery-bypass-grafting-for-multivessel-and-or-left-main-coronary-artery-disease-a-bayesian-network-meta-analysis-of-randomized-controlled-trials
#15
George S Mina, Hussam Watti, Demiana Soliman, Anand Shewale, Jessica Atkins, Pratap Reddy, Paari Dominic
BACKGROUND: Most data guiding revascularization of multivessel disease (MVD) and/or left main disease (LMD) favor coronary artery bypass grafting (CABG) over percutaneous coronary intervention (PCI). However, those data are based on trials comparing CABG to bare metal stents (BMS) or old generation drug eluting stents (OG-DES). Hence, it is essential to outcomes of CABG to those of new generation drug eluting stents (NG-DES). METHODS: We searched PUBMED and Cochrane database for trials evaluating revascularization of MVD and/or LMD with CABG and/or PCI...
January 5, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29395781/editorial-commentary-novel-developments-in-revascularization-for-left-main-coronary-artery-disease
#16
EDITORIAL
Edward T Carreras, Deepak L Bhatt
No abstract text is available yet for this article.
January 26, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29394450/the-expression-of-lipoprotein-receptors-is-increased-in-the-infarcted-area-after-myocardial-infarction-induced-in-rats-with-cardiac-dysfunction
#17
Aline D de Lima, Maria C Guido, Elaine R Tavares, Priscila O Carvalho, Alyne F Marques, Marcelo D T de Melo, Vera M C Salemi, Roberto Kalil-Filho, Raul C Maranhão
Left ventricular (LV) remodeling after myocardial infarction constitutes the structural basis for ventricular dysfunction and heart failure. The characterization underlying the expression of lipoprotein receptors in cardiac dysfunction is scarcely explored. The aim of this study was to analyze the status of lipoprotein receptors on the infarcted and noninfarcted areas of LV and to verify whether nanoparticles that mimic the lipid structure of low-density lipoprotein (LDL) and have the ability to bind to LDL receptors (LDE) are taken up more avidly by the noninfarcted LV...
February 2, 2018: Lipids
https://www.readbyqxmd.com/read/29393604/how-the-functional-assessment-of-culprit-and-non-culprit-lesions-may-improve-stratification-and-treatment-of-stemi-patients
#18
Gianluca Campo, Francesco Gallo, Giulia Bugani, Rita Pavasini, Massimo Fineschi
Reperfusion therapy of the infarct-related artery (IRA) with primary percutaneous coronary intervention (pPCI) is the cornerstone for the treatment of patients with ST-elevation myocardial infarction (STEMI). However, up to 30% of STEMI patients present a multi-vessel coronary artery disease. Several methods are now available for the assessment of functional severity of a coronary stenosis both for IRA and non culprit coronary lesions. The functional assessment of the IRA has mainly a prognostic implication in terms of major adverse cardiovascular events (MACEs), recovery of left ventricular function and evaluation myocardial viability...
February 1, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29390384/migration-of-a-stent-from-left-main-and-its-retrieval-from-femoral-artery-a-case-report
#19
Masakazu Yasuda, Carmen Spaccarotella, Annalisa Mongiardo, Salvatore De Rosa, Daniele Torella, Ciro Indolfi
RATIONALE: Embolization of a deployed stent is a rare complication and its mechanism remains unclear in most cases. PATIENT CONCERNS: A 52-year-old man underwent coronary angiography for effort angina, revealing an 80% stenosis of the proximal left anterior descending (LAD) involving the distal left main (LM). After luminal sizing with intravascular ultrasound two drug-eluting stents were deployed (5.0 × 12 mm and 3.5 × 15 mm) to cover the LM-LAD lesion...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29390352/coronary-artery-aneurysm-combined-with-other-multiple-aneurysms-at-multiple-locations-a-case-report-and-systematic-review
#20
Li-Cheng Jiang, Jia-Yu Cao, Mao Chen
BACKGROUND: Coronary artery aneurysm (CAA) with concomitant aneurysms at multiple sites is quite unusual and rare. The characteristics and the etiology of this phenomenon are unknown. METHODS: Herein, we present a case with right coronary aneurysm with concomitant abdominal aorta as well as right renal artery aneurysm. A systematic review of the literatures regarding CAA with other coexisting aneurysms at multiple locations was also conducted on Medline and Embase databases...
December 2017: Medicine (Baltimore)
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