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https://www.readbyqxmd.com/read/28100199/antioxidant-and-hepatoprotective-potential-of-lawsonia-inermis-l-leaves-against-2-acetylaminofluorene-induced-hepatic-damage-in-male-wistar-rats
#1
Manish Kumar, Paramjeet Kaur, Madhu Chandel, Amrit Pal Singh, Arpana Jain, Satwinderjeet Kaur
BACKGROUND: Lawsonia inermis (Lythraceae) is an ethnomedicinal plant, traditionally known for curing several ailments such as skin diseases, bacterial infections, jaundice, renal lithiases and inflammation etc. The present work deals with assessment of in vitro antioxidant and in vivo hepatoprotective potential of butanolic fraction (But-LI) of Lawsonia inermis L. leaves. METHODS: Antioxidant activity was evaluated using deoxyribose degradation, lipid peroxidation inhibition and ferric reducing antioxidant power (FRAP) assay...
January 18, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28093828/a-systematic-review-on-ethnomedicines-of-anti-cancer-plants
#2
REVIEW
Akash Tariq, Sehrish Sadia, Kaiwen Pan, Ihteram Ullah, Sakina Mussarat, Feng Sun, Olatunji Olusanya Abiodun, Altanzagas Batbaatar, Zilong Li, Dagang Song, Qinli Xiong, Riaz Ullah, Suliman Khan, Buddha Bahadur Basnet, Brawin Kumar, Rabiul Islam, Muhammad Adnan
Cancer is a serious health problem and the second leading cause of death around the globe. Present review is an attempt to provide utmost information based on ethno-pharmacological and toxicological aspects of anti-cancer plants of the world. A total of 276 articles published in English journals and containing maximum ethnomedicinal information were reviewed using several data sources such as; Google scholar, Web of Science, Scopus, PubMed and floras of different countries. A total of 199 anti-cancer plants were recorded in present review and results indicated that traditional medicines are mostly being use in developing countries for cancer treatment...
January 17, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28086924/treating-infants-with-frigg-linking-disease-aetiologies-medicinal-plant-use-and-care-seeking-behaviour-in-southern-morocco
#3
Irene Teixidor-Toneu, Gary J Martin, Rajindra K Puri, Ahmed Ouhammou, Julie A Hawkins
BACKGROUND: Although most Moroccans rely to some extent on traditional medicine, the practice of frigg to treat paediatric ailments by elderly women traditional healers known as ferraggat, has not yet been documented. We describe the role of these specialist healers, document the medicinal plants they use, and evaluate how and why their practice is changing. METHODS: Ethnomedicinal and ethnobotanical data were collected using semi-structured interviews and observations of medical encounters...
January 13, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28064107/ethnomedicine-based-evaluation-of-osteoprotective-properties-of-tinospora-cordifolia-on-in-vitro-and-in-vivo-model-systems
#4
G Abiramasundari, C M Mohan Gowda, G Pampapathi, Sheela Praveen, S Shivamurugan, M Vijaykumar, A Devi, M Sreepriya
Indian ethnomedicine acclaims the use of Tinospora cordifolia (TC) in the treatment of bone fractures and vat rakta (gout). The objective of the study is to investigate the effects of alcoholic extract of Tinospora cordifolia on bone remodeling (involving osteoblastic and osteoclastic actions) in vitro and protect against ovariectomy-induced bone loss in vivo. Human osteoblast-like cells MG-63 and primary osteoblast cells isolated from rat femur were used as osteoblast models and RAW macrophage cell line 264...
January 5, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28063920/reverse-ethnopharmacology-and-drug-discovery
#5
Marco Leonti, Gary I Stafford, Maja Dal Cero, Stefano Cabras, Maria Eugenia Castellanos, Laura Casu, Caroline S Weckerle
ETHNOPHARMACOLOGICAL RELEVANCE: Ethnopharmacological investigations of traditional medicines have made significant contributions to plant-derived drugs, as well as the advancement of pharmacology. Drug discovery from medicinal flora is more complex than generally acknowledged because plants are applied for different therapeutic indications within and across cultures. Therefore we propose the concept of "reverse ethnopharmacology" and compare biomedical uses of plant taxa with their ethnomedicinal and popular uses and test the effect of these on the probability of finding anticancer drugs...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28063919/proteomic-analysis-of-the-protective-effects-of-aqueous-bark-extract-of-terminalia-arjuna-roxb-on-isoproterenol-induced-cardiac-hypertrophy-in-rats
#6
Santosh Kumar, Md Jahangir Alam, Pankaj Prabhakar, Sayeed Ahmad, Subir K Maulik, Manish Sharma, Shyamal K Goswami
ETHNOPHARMACOLOGICAL RELEVANCE: Aqueous bark extract of Terminalia arjuna (TA) has been in use as an ethnomedicine for cardiovascular ailments in the Indian subcontinent for centuries. Studies using hemodynamic, ROS scavenging and anti-inflammatory parameters in animal models have shown its anti-atherogenic, hypotensive, inotropic, anti-inflammatory effects. However, details analysis on its effects on established molecular and cell biological markers are a prerequisite for its wider acceptance to the medical community...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28043127/potential-of-three-ethnomedicinal-plants-as-antisickling-agents
#7
Ismaila O Nurain, Clement O Bewaji, Jarrett S Johnson, Robertson D Davenport, Yang Zhang
Sickle cell disease (SCD) is a genetic blood disorder that affects the shape and transportation of red blood cells (RBCs) in blood vessels, leading to various clinical complications. Many drugs that are available for treating the disease are insufficiently effective, toxic, or too expensive. Therefore, there is a pressing need for safe, effective, and inexpensive therapeutic agents from indigenous plants used in ethnomedicines. The potential of aqueous extracts of Cajanus cajan leaf and seed, Zanthoxylum zanthoxyloides leaf, and Carica papaya leaf in sickle cell disease management was investigated in vitro using freshly prepared 2% sodium metabisulfite for sickling induction...
January 3, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28017696/ethnobiological-treatments-of-neurological-conditions-in-the-chota-nagpur-plateau-india
#8
Abhijit Dey, Partha Gorai, Anuradha Mukherjee, Raghunath Dhan, Biplob Kumar Modak
ETHNOPHARMACOLOGICAL RELEVANCE: World Health Organization (WHO) has recognized the contribution of traditional medicine in the primary health care system. WHO also considers neurological disorders as one of the prime concern to the public health. Inadequate and inaccessible health facilities in the rural and underprivileged areas have forced the various tribal and non-tribal communities to use ethno-phyto and ethno-zoo therapeutics against different ailments. Chota Nagpur Plateau, India is one of the richest in India in terms of plant and animal diversity, and houses a number of indigenous communities often practising their own ethnobiological medicines...
December 22, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28012394/phytochemical-ethnomedicinal-uses-and-pharmacological-profile-of-genus-pistacia
#9
REVIEW
Abdur Rauf, Seema Patel, Ghias Uddin, Bina S Siddiqui, Bashir Ahmad, Naveed Muhammad, Yahia N Mabkhot, Taibi Ben Hadda
Pistacia genus belong to family Anacardiaceae and it is versatile in that its member species have food (P. vera), medicinal (P. lentiscus) and ornamental (P. chinensis) values. Various species of this genus have folkloric uses with credible mention in diverse pharmacopeia. As a trove of phenolic compounds, terpenoids, monoterpenes, flavonoids, alkaloids, saponins, fatty acids, and sterols, this genus has garnered pharmaceutical attention in recent times. With adequate clinical studies, this genus might be exploited for therapy of a multitude of inflammatory diseases, as promised by preliminary studies...
December 21, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27994630/corrigendum-to-use-of-ethnomedicinal-plants-by-the-people-living-around-indus-river
#10
Sakina Mussarat, Naser M AbdEl-Salam, Akash Tariq, Sultan Mehmood Wazir, Riaz Ullah, Muhammad Adnan
[This corrects the article DOI: 10.1155/2014/212634.].
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27989875/ethnobotany-phytochemistry-toxicology-and-pharmacological-properties-of-terminalia-sericea-burch-ex-dc-combretaceae-a-review
#11
REVIEW
N I Mongalo, L J McGaw, T V Segapelo, J F Finnie, J Van Staden
ETHNOPHARMACOLOGICAL REFERENCE: The use of medicinal plants in the treatment of infections is ancient. A wide variety of ethnotherapeutic properties and pharmacological actions has been attributed to Terminalia sericea. Studies by various groups of investigators reveal that it is a multipurpose medicinal plant used mostly in the treatment of diarrhoea, sexually transmitted infections, skin rashes, tuberculosis and other infections. The current paper is aimed at providing an overview of the ethnomedicinal uses, toxicology, pharmacology and the phytochemistry of Terminalia sericea...
October 27, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27955739/phytochemical-overview-and-medicinal-importance-of-coffea-species-from-the-past-until-now
#12
REVIEW
Éva Brigitta Patay, Tímea Bencsik, Nóra Papp
Coffea (coffee) species are grown in almost all countries along the Equator. Many members of the genus have a large production history and an important role both in the global market and researches. Seeds (Coffeae semen) are successfully used in food, cosmetic, and pharmaceutical industries due to its caffeine and high polyphenol content. Nowadays, the three best-known coffee species are Arabic (Coffea arabica L.), Robusta (Coffea robusta L. Linden), and Liberian coffees (Coffea liberica Hiern.). Even though, many records are available on coffee in scientific literature, wild coffee species like Bengal coffee (Coffea benghalensis Roxb...
December 2016: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/27905101/a-review-on-antiviral-activity-of-the-himalayan-medicinal-plants-traditionally-used-to-treat-bronchitis-and-related-symptoms
#13
REVIEW
Rahila Amber, Muhammad Adnan, Akash Tariq, Sakina Mussarat
OBJECTIVES: Bronchitis is a common respiratory tract infection of humans mainly caused by influenza virus, rhinovirus, adenovirus, coronavirus and respiratory syncytial virus. The aim of this review was to gather fragmented literature on ethnomedicinal plants used against bronchitis in the Himalayan region and their in-vitro validation against bronchitis causing viral pathogens. KEY FINDINGS: Present review contains ethnomedicines of total 55 plants from different countries of the Himalayas...
February 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/27900356/graphical-dataset-on-important-medicinal-plants-used-for-curing-dental-issues-in-manoor-valley-mansehra-pakistan
#14
Inayat Ur Rahman, Farhana Ijaz, Aftab Afzal, Zafar Iqbal, Niaz Ali, Muhammad Azhar Khan, Muhammad Afzal, Said Muhammad, Ghulam Qadir, Muhammad Asif
The graphical dataset in this paper is related to the research article entitled "A novel survey of the ethno medicinal knowledge of dental problems in Manoor Valley (Northern Himalaya), Pakistan" (I.U. Rahman, F. Ijaz, Z. Iqbal, A. Afzal, N. Ali, M. Afzal, M.A. Khan, S. Muhammad, G. Qadir, M. Asif, 2016) [1]. This article describes how the local community of Manoor Valley practices cultural / traditional knowledge for dental problems. For the recorded data of 25 medicinal plants, six quantitative ethnomedicinal statistical approaches / equations were used...
December 2016: Data in Brief
https://www.readbyqxmd.com/read/27876502/oldenlandia-diffusa-suppresses-metastatic-potential-through-inhibiting-matrix-metalloproteinase-9-and-intercellular-adhesion-molecule-1-expression-via-p38-and-erk1-2-mapk-pathways-and-induces-apoptosis-in-human-breast-cancer-mcf-7-cells
#15
Tae-Wook Chung, Hyunju Choi, Ji-Min Lee, Sun-Hyung Ha, Choong-Hwan Kwak, Fukushi Abekura, Jun-Young Park, Young-Chae Chang, Ki-Tae Ha, Seung-Hak Cho, Hyeun Wook Chang, Young-Choon Lee, Cheorl-Ho Kim
ETHNOPHARMACOLOGY RELEVANCE: Oldenlandia diffusa (OD) has long been known as an apoptotic inducer in breast tumors in ethnomedicine. AIM OF THE STUDY: To scientifically confirm the anti-breast cancer effects of water, methanol (MeOH) and butanol (BuOH) extracts of O. diffusa on cell apoptosis, matrix metalloproteinases (MMPs), intercellular adhesion molecule (ICAM)-1 and intracellular signaling in MCF-7 breast cancer cells. MATERIALS AND METHODS: MeOH extracts (MOD) and BuOH extracts (BOD) were prepared and examined for their ability to inhibit phorbol myristate acetate (PMA)-induced matrix metalloproteinase (MMP)-9 and intercellular adhesion molecule (ICAM)-1 expressions in MCF-7 human breast cancer cells...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27872572/evaluation-of-the-diuretic-and-urinary-electrolyte-effects-of-methanolic-extract-of-peganum-harmala-l-in-wistar-albino-rats
#16
Fahad I Al-Saikhan, Mohd N Ansari
The use of traditional medicines as a diuretic agent has been increasing in recent years. The diuretic activity of a number of plant extracts used as diuretic agents in ethnomedicine has been confirmed in experimental animals. However, despite the widespread use of Peganum harmala in traditional medicine, there is a paucity of data supporting its use as a diuretic agent. Therefore, the present study aimed to envisage the true effect and magnitude of diuresis of methanolic extract of P. harmala (MEPH) in comparison with a well-known diuretic drug furosemide using Wistar albino rats...
November 2016: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/27865008/biosynthesis-of-the-psychotropic-plant-diterpene-salvinorin-a-discovery-and-characterization-of-the-salvia-divinorum-clerodienyl-diphosphate-synthase
#17
Kyle A Pelot, Rod Mitchell, Moonhyuk Kwon, David M Hagelthorn, Jacob F Wardman, Angela Chiang, Jörg Bohlmann, Dae-Kyun Ro, Philipp Zerbe
Salvia divinorum commonly known as diviner's sage, is an ethnomedicinal plant of the mint family (Lamiaceae). S. divinorum is rich in clerodane-type diterpenoids, which accumulate predominantly in leaf glandular trichomes. The main bioactive metabolite, salvinorin A, is the first non-nitrogenous natural compound known to function as an opioid-receptor agonist, and is undergoing clinical trials for potential use in treating neuropsychiatric diseases and drug addictions. We report here the discovery and functional characterization of two S...
November 19, 2016: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/27864113/chenopodium-album-linn-leaves-prevent-ethylene-glycol-induced-urolithiasis-in-rats
#18
Indu Sikarwar, Yadu Nandan Dey, Manish M Wanjari, Ajay Sharma, Sudesh N Gaidhani, Ankush D Jadhav
ETHNOPHARMACOLOGICAL RELEVANCE: The leaves of Chenopodium album Linn. are traditionally used for correction of kidney diseases and urinary stones. The present work investigated the effect of methanolic and aqueous extracts of leaves of Chenopodium album on experimentally-induced urolithiasis in rats to substantiate its traditional use as antilithiatic agent. MATERIALS AND METHODS: The leaf extract was standardized by HPLC. Urolithiasis was induced in rats by administration of 0...
January 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27849252/profiling-of-antioxidant-potential-and-phytoconstituents-of-plantago-coronopus
#19
C G Pereira, L Custódio, M J Rodrigues, N R Neng, J M F Nogueira, J Carlier, M C Costa, J Varela, L Barreira
The halophyte species Plantago coronopus has several described ethnomedicinal uses, but few reported biological activities. This work carried out for the first time a comparative analysis of P. coronopus organs in terms of phenolic composition and antioxidant activity of organic and water extracts from roots, leaves and flowers. The leaves contents in selected nutrients, namely amino acids and minerals, are also described. Roots (ethyl acetate and methanol extracts) had the highest radical scavenging activity (RSA) towards 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals, while leaves (hexane extract) had higher RSA on nitric oxide radical and iron chelating ability...
November 16, 2016: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/27846856/ethno-medicinal-survey-of-important-plants-practiced-by-indigenous-community-at-ladha-subdivision-south-waziristan-agency-pakistan
#20
Muhammad Abdul Aziz, Muhammad Adnan, Amir Hasan Khan, Atiq Ur Rehman, Rahmatullah Jan, Jafar Khan
BACKGROUND: Medicinal flora plays a vital role in treating various types of ailments in living beings. The present study was planned to investigate and document systematically the indigenous knowledge in a scientifically little explored area of Ladha sub-division, South Waziristan agency, Pakistan. Hence, this study would contribute positively to the field of ethnopharmacology. METHODS: Prior to ethnomedicinal data collection, regular field visits were conducted during the month of May and June 2015 to locate the sites and respondents from where the traditional knowledge was to be recorded...
November 15, 2016: Journal of Ethnobiology and Ethnomedicine
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