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Ethnomedicine

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https://www.readbyqxmd.com/read/28427292/chemical-analyses-and-in-vitro-and-in-vivo-toxicity-of-fruit-methanol-extract-of-sechium-edule-var-nigrum-spinosum
#1
Itzen Aguiñiga-Sánchez, Jorge Cadena-Íñiguez, Edelmiro Santiago-Osorio, Guadalupe Gómez-García, Víctor Manuel Mendoza-Núñez, Juana Rosado-Pérez, Mirna Ruíz-Ramos, Víctor Manuel Cisneros-Solano, Edgar Ledesma-Martínez, Angel de Jesus Delgado-Bordonave, Ramón Marcos Soto-Hernández
CONTEXT: Sechium edule (Jacq.) Sw. (Cucurbitaceae) is used in ethnomedicine, but the diversity of the varietal groups of this species has not often been considered. This is important because we previously reported that different variety of species exhibit different activities across different tumor cell lines. OBJECTIVE: This study investigates the chemical composition and biological activities of extracts obtained from S. edule var. nigrum spinosum. MATERIALS AND METHODS: The leukemia P388 cell line and mononuclear bone marrow cells (MNCBMs) were treated with the extract at a concentration ranging from 40 to 2370 μg/mL for cytotoxicity and viability assays...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28425043/innovative-development-path-of-ethnomedicines-a-case-study
#2
Zhaoyun Zhu, Yali Gui, Li Wang, Ting Wang, Yang Yang, Yunzhuang Niu, Dehuan Fu, Jingkun Wang, Tao Cui
Innovative development extends the vitality of ethnomedicines. Developing ethnomedicines is not only beneficial to the public but also to the related industry and transforms economic growth, driving local social and economic development further. Its economic benefit can be used to optimize and promote the hardware and software of the platform, as well as support the sustainable development of ethnomedicines. Apart from research and discussion on the innovative development of ethnomedicines on the basis of theory and regulations, this series of articles also summarizes cases that are conducive to the overall understanding of the necessity and feasibility of the innovative development...
April 19, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/28376640/antimicrobial-activity-of-buchenavia-tetraphylla-against-candida-albicans-strains-isolated-from-vaginal-secretions
#3
José Robson Neves Cavalcanti Filho, Tiago Fonseca Silva, Woah Queiroz Nobre, Larissa Isabela Oliveira de Souza, Cristiane Santos Silva E Silva Figueiredo, Regina Celia Bressan Queiroz de Figueiredo, Norma Buarque de Gusmão, Márcia Vanusa Silva, Luís Cláudio Nascimento da Silva, Maria Tereza Dos Santos Correia
CONTEXT: Buchenavia tetraphylla (Aubl.) RA Howard (Combretaceae: Combretoideae) is an ethnomedicinal plant with reported antifungal action. OBJECTIVE: This study evaluates the antimicrobial activity of B. tetraphylla leaf extracts against clinical isolates of Candida albicans. The morphological alterations, combinatory effects with fluconazole and the cytotoxicity of the active extract were analyzed. MATERIALS AND METHODS: Extracts were obtained using different solvents (hexane: BTHE; chloroform: BTCE; ethyl acetate: BTEE; and methanol: BTME)...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28363524/a-systematic-overview-of-leucosidea-sericea-a-multi-purpose-tree-with-great-potential-as-phytomedicine
#4
REVIEW
Tshepiso C Mafole, Adeyemi O Aremu, Thandekile Mthethwa, Mack Moyo
ETHNOPHARMACOLOGICAL RELEVANCE: Leucosidea sericea is a tree species found in southern Africa and possess several therapeutical effects against infectious diseases in humans and livestock. Increasing evidence on the efficacy of the species have demonstrated noteworthy biological potential. AIMS OF THE REVIEW: To comprehensively document and summarize the botany, biological and phytochemical properties of Leucosidea sericea, a monotypic species in the genus Leucosidea...
March 28, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28359849/a-review-on-traditional-uses-phytochemistry-pharmacology-pharmacokinetics-and-toxicology-of-the-genus-peganum
#5
REVIEW
Shuping Li, Xuemei Cheng, Changhong Wang
ETHNOPHARMACOLOGICAL RELEVANCE: The plants of the genus Peganum have a long history as a Chinese traditional medicine for the treatment of cough, hypertension, diabetes, asthma, jaundice, colic, lumbago, and many other human ailments. Additionally, the plants can be used as an amulet against evil-eye, dye and so on, which have become increasingly popular in Asia, Iran, Northwest India, and North Africa. AIM OF THE REVIEW: The present paper reviewed the ethnopharmacology, phytochemistry, analytical methods, biological activities, metabolism, pharmacokinetics, toxicology, and drug interaction of the genus Peganum in order to assess the ethnopharmacological use and to explore therapeutic potentials and future opportunities for research...
March 27, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28347832/the-genus-achyranthes-a-review-on-traditional-uses-phytochemistry-and-pharmacological-activities
#6
REVIEW
Xirui He, Xiaoxiao Wang, Jiacheng Fang, Yu Chang, Ning Ning, Hao Guo, Linhong Huang, Xiaoqiang Huang
ETHNOPHARMACOLOGICAL RELEVANCE: Achyranthes L. (Amaranthaceae), also known as Chaff Flower and Niuxi/, mainly includes two famous medicinal species namely A. bidentata and A. aspera. A. bidentata has been widely used as blood-activating and stasis-resolving medicine for the treatment of various diseases including amenorrhea, dysmenorrhea, lumbago, gonalgia, paraplegia, edema, stranguria, headache, dizziness, odontalgia, oral ulcer, hematemesis, and epistaxis. A. aspera has been widely used to treat various diseases, including gynecological disorder, asthma, ophthalmia, odontalgia, haemorrhoids, and abdominal tumor, and has been applied to difficult labour, wound healing, insect and snake bites...
March 24, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28344493/volatile-constituents-and-biological-activities-of-the-leaf-and-root-of-echinacea-species-from-south-africa
#7
M Nyalambisa, I A Oyemitan, R Matewu, O O Oyedeji, O S Oluwafemi, S P Songca, B N Nkeh-Chungag, A O Oyedeji
Echinacea is used ethnomedicinally for the treatment of various diseases such as cough, respiratory infections, and bronchitis among other uses in Eastern Cape region of South Africa. This study evaluated the volatile components of the essential oil of the plant, its toxicity, anti-inflammatory and analgesic activities in rodents. Dried leaf and root of the plant were separately processed by hydrodistillation for 4 h and their essential oils (EOs) were collected. Extracted oils were subjected to GC/GC-MS analysis...
March 2017: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
https://www.readbyqxmd.com/read/28333074/assessment-of-the-anti-hyperglycaemic-anti-inflammatory-and-antioxidant-activities-of-the-methanol-extract-of-moringa-oleifera-in-diabetes-induced-nephrotoxic-male-wistar-rats
#8
Elizabeth I Omodanisi, Yapo G Aboua, Oluwafemi O Oguntibeju
Diabetes mellitus is an endocrine disease of multiple aetiologies in insulin secretion. A deficiency in insulin results in hyperglycemia with metabolic disturbances of biomolecules. Moringa oleifera (MO) is endemic in the tropics with a variety of ethnomedicinal importance. The leaf of this plant has been reported to possess antioxidant and medicinal properties that may be helpful in the treatment and management of diabetes and its associated complications. Diabetes was induced intraperitoneally in rats by a single dose of streptozotocin (55 mg/kg) and treated with methanolic extract of Moringa oleifera (250 mg/kg b...
March 23, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28330725/a-botanical-phytochemical-and-ethnomedicinal-review-of-the-genus-mitragyna-korth-implications-for-products-sold-as-kratom
#9
REVIEW
Paula N Brown, Jensen A Lund, Susan J Murch
ETHNOPHARMACOLOGICAL RELEVANCE: The genus Mitragyna (Rubiacaeae) has been traditionally used in parts of Africa, Asia and Oceania. In recent years, there has been increased interest in species of Mitragyna with the introduction of products to western markets and regulatory uncertainty. AIM OF THE STUDY: This paper reviewed the traditional ethnomedicinal uses of leaves for species belonging to the genus Mitragyna with reference to the botany and known chemistry in order to highlight areas of interest for products currently being sold as kratom...
March 18, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28330204/endophytic-fungal-isolate-mediated-biosynthesis-of-silver-nanoparticles-and-their-free-radical-scavenging-activity-and-anti-microbial-studies
#10
Vasudeva Reddy Netala, Venkata Subbaiah Kotakadi, Pushpalatha Bobbu, Susmila Aparna Gaddam, Vijaya Tartte
The present study reports that the biosynthesis of AgNPs using an endophytic fungus isolated from the ethnomedicinal plant Centella asiatica. The endophytic fungus was identified as Aspergillus versicolor ENT7 based on 18S rRNA gene sequencing (NCBI Accession number KF493864). The AgNPs synthesized were characterized by UV-visible spectroscopy, Fourier transform infra-red spectroscopy (FTIR), transmission electron microscopy (TEM), X-ray diffraction (XRD), particle size analyzer, and zeta potential measurements...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28327127/effects-of-vitellaria-paradoxa-c-f-gaertn-aqueous-leaf-extract-administration-on-salmonella-typhimurium-infected-rats
#11
Siméon Pierre Chegaing Fodouop, Sedric Donald Tala, Lunga Paul Keilah, Norbert Kodjio, Mefokou Didiane Yemele, Armel Herve Kamdje Nwabo, Bridget Nji-Kah, Joseph Tchoumboue, Donatien Gatsing
BACKGROUND: The present study investigates the effects of Vitellaria paradoxa crude extract administration on Salmonella typhimurium infected Wistar rats. METHODS: Rats were infected by single dose oral administration of Salmonella typhimurium (1.5×10(8) CFU). Negative control groups were infected and treated orally with distilled water (vehicle), neutral control group were not infected, while the four test groups were treated up to 18 days with 55 mg/kg, 110 mg/kg, 220 mg/kg and 440 mg/kg body weight of aqueous extract of V...
March 21, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28320254/antimalarial-and-antiplasmodial-activity-of-husk-extract-and-fractions-of-zea-mays
#12
Jude E Okokon, Bassey S Antia, Dinesh Mohanakrishnan, Dinkar Sahal
CONTEXT: Zea mays L. (Poacae) husk decoctions are traditionally used in the treatment of malaria by various tribes in Nigeria. OBJECTIVE: To assess the antimalarial and antiplasmodial potentials of the husk extract and fractions on malaria parasites using in vivo and in vitro models. MATERIALS AND METHODS: The ethanol husk extract and fractions (187-748 mg/kg, p.o.) of Zea mays were investigated for antimalarial activity against Plasmodium berghei using rodent (mice) malaria models and in vitro activity against chloroquine sensitive (Pf 3D7) and resistant (Pf INDO) strains of Plasmodium falciparum using the SRBR green assay method...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28303220/anemone-medicinal-plants-ethnopharmacology-phytochemistry-and-biology
#13
REVIEW
Da-Cheng Hao, Xiaojie Gu, Peigen Xiao
The Ranunculaceae genus Anemone (order Ranunculales), comprising more than 150 species, mostly herbs, has long been used in folk medicine and worldwide ethnomedicine. Various medicinal compounds have been found in Anemone plants, especially triterpenoid saponins, some of which have shown anti-cancer activities. Some Anemone compounds and extracts display immunomodulatory, anti-inflammatory, antioxidant, and antimicrobial activities. More than 50 species have ethnopharmacological uses, which provide clues for modern drug discovery...
March 2017: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/28289385/plant-derived-phytocompound-embelin-in-cns-disorders-a-systematic-review
#14
REVIEW
Uday P Kundap, Saatheeyavaane Bhuvanendran, Yatinesh Kumari, Iekhsan Othman, Mohd Farooq Shaikh
A Central nervous system (CNS) disease is the one which affects either the spinal cord or brain and causing neurological or psychiatric complications. During the nineteenth century, modern medicines have occupied the therapy for many ailments and are widely used these days. Herbal medicines have often maintained popularity for historical and cultural reasons and also considered safer as they originate from natural sources. Embelin is a plant-based benzoquinone which is the major active constituent of the fruits of Embelia ribes Burm...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28282293/preliminary-phytochemical-analysis-and-evaluation-of-antioxidant-cytotoxic-and-inhibition-of-lipopolysaccaride-induced-nos-inos-expression-in-balb-c-mice-liver-by-ziziphus-oenoplia-mill-fruit
#15
Ramaraj Thirugnanasampandan, Gunasekar Ramya, Gunasekaran Bhuvaneswari, Srinivasan Aravindh, Suresh Vaishnavi, Madhusudhanan Gogulramnath
BACKGROUND: Ziziphus oenoplia Mill. is an ethnomedicinal plant and its fruit has been traditionally used by Puliar tribes of Anamalai Hills, Tamil Nadu, India to treat various ailments. Phytochemical analysis, antioxidant, cytotoxic and inducible nitric oxide synthase (iNOS) gene downregulation activities of Z. oenoplia fruit (ZOF) were studied. METHODS: To explore bioactive compounds present in the ripened fruits, high-performance thin-layer chromatography (HPTLC) and gas chromatography/mass spectrometry (GC-MS) analysis were done...
March 10, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28266011/traditional-uses-phytochemistry-and-pharmacology-of-the-medicinal-species-of-the-genus-cordia-boraginaceae
#16
REVIEW
Manisha J Oza, Yogesh A Kulkarni
OBJECTIVES: Cordia (family Boraginaceae) is a genus of deciduous flowering trees or shrubs comprising more than 300 species distributed widely in the tropical regions. The aim of this review was to provide exhaustive scientific information on traditional uses, phytochemistry and pharmacological activities of the 36 important species with medicinal value from the genus Cordia, to divulge prospects for further research on its therapeutic potential. KEY FINDINGS: Leaves, fruit, bark and seed of a majority of the species were found to possess abundant ethnomedicinal value, but leaves were found to be used most frequently to treat many ailments such as respiratory disorders, stomach pain, wound, inflammation, myalgia, cough, dysentery and diarrhoea...
March 7, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28265550/in-vitro-and-in-vivo-antioxidant-potentials-of-alchornea-floribunda-leaf-extract-fractions-and-isolated-bioactive-compounds
#17
Daniel Lotanna Ajaghaku, Okechukwu Obasi, Blessing Ogechukwu Umeokoli, Peter Ogbuatu, Chukwuemeka Sylvester Nworu, Emmanuel Emeka Ilodigwe, Festus Basden Chiedu Okoye
OBJECTIVE: Alchornea floribunda leaves are widely used in ethnomedicine for the management of immuno-inflammatory disorders. We investigated the in vivo and in vitro antioxidant activity of the leaf extract, fractions and isolated compounds of A. floribunda. MATERIALS AND METHODS: The ethyl acetate fraction of the methanol leaf extract was subjected to several chromatographic separations to isolate compounds 1-4. The structures of the isolated compounds were elucidated by a combination of 1D and 2D NMR and mass spectrometry...
January 2017: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28265493/transcriptome-analysis-of-polygonum-minus-reveals-candidate-genes-involved-in-important-secondary-metabolic-pathways-of-phenylpropanoids-and-flavonoids
#18
Kok-Keong Loke, Reyhaneh Rahnamaie-Tajadod, Chean-Chean Yeoh, Hoe-Han Goh, Zeti-Azura Mohamed-Hussein, Zamri Zainal, Ismanizan Ismail, Normah Mohd Noor
BACKGROUND: Polygonum minus is an herbal plant in the Polygonaceae family which is rich in ethnomedicinal plants. The chemical composition and characteristic pungent fragrance of Polygonum minus have been extensively studied due to its culinary and medicinal properties. There are only a few transcriptome sequences available for species from this important family of medicinal plants. The limited genetic information from the public expressed sequences tag (EST) library hinders further study on molecular mechanisms underlying secondary metabolite production...
2017: PeerJ
https://www.readbyqxmd.com/read/28237473/phytochemical-and-ethnopharmacological-review-of-elephantorrhiza-goetzei-harms-harms
#19
REVIEW
Alfred Maroyi
Elephantorrhiza goetzei (E. goetzei) commonly known as Goetze's elephantorrhiza, is traditionally used as a decoction in the treatment of a variety of conditions such as pain, sores, sexually transmitted infections (STIs), gastro-intestinal disorders, microbial infections and genito-urinary system disorders. On the basis of its wide distribution in south central Africa, E. goetzei has a long history of applications among the different ethnic groups. A total of 23 ethnomedicinal uses of E. goetzei are documented in this study from 62...
February 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28220457/innovative-development-path-of-ethnomedicines-the-interpretation-of-the-path
#20
REVIEW
Zhaoyun Zhu, Dehuan Fu, Yali Gui, Tao Cui, Jingkun Wang, Ting Wang, Zhizhong Yang, Yanfei Niu, Zhennan She, Li Wang
One of the primary purposes of the innovative development of ethnomedicines is to use their excellent safety and significant efficacy to serve a broader population. To achieve this purpose, modern scientific and technological means should be referenced, and relevant national laws and regulations as well as technical guides should be strictly followed to develop standards and to perform systemic research in producing ethnomedicines. Finally, ethnomedicines, which are applied to a limited extent in ethnic areas, can be transformed into safe, effective, and quality-controllable medical products to relieve the pain of more patients...
February 21, 2017: Frontiers of Medicine
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