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Ethnomedicine

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https://www.readbyqxmd.com/read/28330204/endophytic-fungal-isolate-mediated-biosynthesis-of-silver-nanoparticles-and-their-free-radical-scavenging-activity-and-anti-microbial-studies
#1
Vasudeva Reddy Netala, Venkata Subbaiah Kotakadi, Pushpalatha Bobbu, Susmila Aparna Gaddam, Vijaya Tartte
The present study reports that the biosynthesis of AgNPs using an endophytic fungus isolated from the ethnomedicinal plant Centella asiatica. The endophytic fungus was identified as Aspergillus versicolor ENT7 based on 18S rRNA gene sequencing (NCBI Accession number KF493864). The AgNPs synthesized were characterized by UV-visible spectroscopy, Fourier transform infra-red spectroscopy (FTIR), transmission electron microscopy (TEM), X-ray diffraction (XRD), particle size analyzer, and zeta potential measurements...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28327127/effects-of-vitellaria-paradoxa-c-f-gaertn-aqueous-leaf-extract-administration-on-salmonella-typhimurium-infected-rats
#2
Siméon Pierre Chegaing Fodouop, Sedric Donald Tala, Lunga Paul Keilah, Norbert Kodjio, Mefokou Didiane Yemele, Armel Herve Kamdje Nwabo, Bridget Nji-Kah, Joseph Tchoumboue, Donatien Gatsing
BACKGROUND: The present study investigates the effects of Vitellaria paradoxa crude extract administration on Salmonella typhimurium infected Wistar rats. METHODS: Rats were infected by single dose oral administration of Salmonella typhimurium (1.5×10(8) CFU). Negative control groups were infected and treated orally with distilled water (vehicle), neutral control group were not infected, while the four test groups were treated up to 18 days with 55 mg/kg, 110 mg/kg, 220 mg/kg and 440 mg/kg body weight of aqueous extract of V...
March 21, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28320254/antimalarial-and-antiplasmodial-activity-of-husk-extract-and-fractions-of-zea-mays
#3
Jude E Okokon, Bassey S Antia, Dinesh Mohanakrishnan, Dinkar Sahal
CONTEXT: Zea mays L. (Poacae) husk decoctions are traditionally used in the treatment of malaria by various tribes in Nigeria. OBJECTIVE: To assess the antimalarial and antiplasmodial potentials of the husk extract and fractions on malaria parasites using in vivo and in vitro models. MATERIALS AND METHODS: The ethanol husk extract and fractions (187-748 mg/kg, p.o.) of Zea mays were investigated for antimalarial activity against Plasmodium berghei using rodent (mice) malaria models and in vitro activity against chloroquine sensitive (Pf 3D7) and resistant (Pf INDO) strains of Plasmodium falciparum using the SRBR green assay method...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28303220/anemone-medicinal-plants-ethnopharmacology-phytochemistry-and-biology
#4
REVIEW
Da-Cheng Hao, Xiaojie Gu, Peigen Xiao
The Ranunculaceae genus Anemone (order Ranunculales), comprising more than 150 species, mostly herbs, has long been used in folk medicine and worldwide ethnomedicine. Various medicinal compounds have been found in Anemone plants, especially triterpenoid saponins, some of which have shown anti-cancer activities. Some Anemone compounds and extracts display immunomodulatory, anti-inflammatory, antioxidant, and antimicrobial activities. More than 50 species have ethnopharmacological uses, which provide clues for modern drug discovery...
March 2017: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/28289385/plant-derived-phytocompound-embelin-in-cns-disorders-a-systematic-review
#5
REVIEW
Uday P Kundap, Saatheeyavaane Bhuvanendran, Yatinesh Kumari, Iekhsan Othman, Mohd Farooq Shaikh
A Central nervous system (CNS) disease is the one which affects either the spinal cord or brain and causing neurological or psychiatric complications. During the nineteenth century, modern medicines have occupied the therapy for many ailments and are widely used these days. Herbal medicines have often maintained popularity for historical and cultural reasons and also considered safer as they originate from natural sources. Embelin is a plant-based benzoquinone which is the major active constituent of the fruits of Embelia ribes Burm...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28282293/preliminary-phytochemical-analysis-and-evaluation-of-antioxidant-cytotoxic-and-inhibition-of-lipopolysaccaride-induced-nos-inos-expression-in-balb-c-mice-liver-by-ziziphus-oenoplia-mill-fruit
#6
Ramaraj Thirugnanasampandan, Gunasekar Ramya, Gunasekaran Bhuvaneswari, Srinivasan Aravindh, Suresh Vaishnavi, Madhusudhanan Gogulramnath
BACKGROUND: Ziziphus oenoplia Mill. is an ethnomedicinal plant and its fruit has been traditionally used by Puliar tribes of Anamalai Hills, Tamil Nadu, India to treat various ailments. Phytochemical analysis, antioxidant, cytotoxic and inducible nitric oxide synthase (iNOS) gene downregulation activities of Z. oenoplia fruit (ZOF) were studied. METHODS: To explore bioactive compounds present in the ripened fruits, high-performance thin-layer chromatography (HPTLC) and gas chromatography/mass spectrometry (GC-MS) analysis were done...
March 10, 2017: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/28266011/traditional-uses-phytochemistry-and-pharmacology-of-the-medicinal-species-of-the-genus-cordia-boraginaceae
#7
REVIEW
Manisha J Oza, Yogesh A Kulkarni
OBJECTIVES: Cordia (family Boraginaceae) is a genus of deciduous flowering trees or shrubs comprising more than 300 species distributed widely in the tropical regions. The aim of this review was to provide exhaustive scientific information on traditional uses, phytochemistry and pharmacological activities of the 36 important species with medicinal value from the genus Cordia, to divulge prospects for further research on its therapeutic potential. KEY FINDINGS: Leaves, fruit, bark and seed of a majority of the species were found to possess abundant ethnomedicinal value, but leaves were found to be used most frequently to treat many ailments such as respiratory disorders, stomach pain, wound, inflammation, myalgia, cough, dysentery and diarrhoea...
March 7, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28265550/in-vitro-and-in-vivo-antioxidant-potentials-of-alchornea-floribunda-leaf-extract-fractions-and-isolated-bioactive-compounds
#8
Daniel Lotanna Ajaghaku, Okechukwu Obasi, Blessing Ogechukwu Umeokoli, Peter Ogbuatu, Chukwuemeka Sylvester Nworu, Emmanuel Emeka Ilodigwe, Festus Basden Chiedu Okoye
OBJECTIVE: Alchornea floribunda leaves are widely used in ethnomedicine for the management of immuno-inflammatory disorders. We investigated the in vivo and in vitro antioxidant activity of the leaf extract, fractions and isolated compounds of A. floribunda. MATERIALS AND METHODS: The ethyl acetate fraction of the methanol leaf extract was subjected to several chromatographic separations to isolate compounds 1-4. The structures of the isolated compounds were elucidated by a combination of 1D and 2D NMR and mass spectrometry...
January 2017: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28265493/transcriptome-analysis-of-polygonum-minus-reveals-candidate-genes-involved-in-important-secondary-metabolic-pathways-of-phenylpropanoids-and-flavonoids
#9
Kok-Keong Loke, Reyhaneh Rahnamaie-Tajadod, Chean-Chean Yeoh, Hoe-Han Goh, Zeti-Azura Mohamed-Hussein, Zamri Zainal, Ismanizan Ismail, Normah Mohd Noor
BACKGROUND: Polygonum minus is an herbal plant in the Polygonaceae family which is rich in ethnomedicinal plants. The chemical composition and characteristic pungent fragrance of Polygonum minus have been extensively studied due to its culinary and medicinal properties. There are only a few transcriptome sequences available for species from this important family of medicinal plants. The limited genetic information from the public expressed sequences tag (EST) library hinders further study on molecular mechanisms underlying secondary metabolite production...
2017: PeerJ
https://www.readbyqxmd.com/read/28237473/phytochemical-and-ethnopharmacological-review-of-elephantorrhiza-goetzei-harms-harms
#10
REVIEW
Alfred Maroyi
Elephantorrhiza goetzei (E. goetzei) commonly known as Goetze's elephantorrhiza, is traditionally used as a decoction in the treatment of a variety of conditions such as pain, sores, sexually transmitted infections (STIs), gastro-intestinal disorders, microbial infections and genito-urinary system disorders. On the basis of its wide distribution in south central Africa, E. goetzei has a long history of applications among the different ethnic groups. A total of 23 ethnomedicinal uses of E. goetzei are documented in this study from 62...
February 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28220457/innovative-development-path-of-ethnomedicines-the-interpretation-of-the-path
#11
REVIEW
Zhaoyun Zhu, Dehuan Fu, Yali Gui, Tao Cui, Jingkun Wang, Ting Wang, Zhizhong Yang, Yanfei Niu, Zhennan She, Li Wang
One of the primary purposes of the innovative development of ethnomedicines is to use their excellent safety and significant efficacy to serve a broader population. To achieve this purpose, modern scientific and technological means should be referenced, and relevant national laws and regulations as well as technical guides should be strictly followed to develop standards and to perform systemic research in producing ethnomedicines. Finally, ethnomedicines, which are applied to a limited extent in ethnic areas, can be transformed into safe, effective, and quality-controllable medical products to relieve the pain of more patients...
February 21, 2017: Frontiers of Medicine
https://www.readbyqxmd.com/read/28216948/averrhoa-bilimbi-linn-a-review-of-its-ethnomedicinal-uses-phytochemistry-and-pharmacology
#12
REVIEW
Alhassan Muhammad Alhassan, Qamar Uddin Ahmed
Averrhoa bilimbi Linn. is principally cultivated for medicinal purposes in many tropical and subtropical countries of the world. Literature survey about this plant shows that A. bilimbi is mainly used as a folk medicine in the treatment of diabetes mellitus, hypertension, and as an antimicrobial agent. The prime objective of this review is to accumulate and organize literature based on traditional claims and correlate those with current findings on the use of A. bilimbi in the management of different ailments...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28215152/biological-activities-of-sesquiterpene-lactones-isolated-from-the-genus-centaurea-l-asteraceae
#13
Marina Sokovic, Ana Ciric, Jasmina Glamoclija, Helen Skaltsa
BACKGROUND: In recent years, a growing interest has developed in the field of biological activity of plant metabolites. Research in this area considering antimicrobial, antioxidant, cytotoxic, anti-inflammatory, and other properties, is currently expanding, reporting various species to possess such biological effects. Among them, Centaurea species are well known to be used in ethnomedicine. The Centaurea genus (Asteraceae) is represented by more than 500 species, mostly located in the Mediterranean region and Western Asia...
February 15, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28198202/clinacanthus-nutans-a-review-on-ethnomedicinal-uses-chemical-constituents-and-pharmacological-properties
#14
REVIEW
Ihsan N Zulkipli, Rajan Rajabalaya, Adi Idris, Nurul Atiqah Sulaiman, Sheba R David
CONTEXT: Medicinal plants have attracted global attention for their hidden therapeutic potential. Clinacanthus nutans (Burm.f) Lindau (Acanthaceae) (CN) is endemic in Southeast Asia. CN contains phytochemicals common to medicinal plants, such as flavonoids. Traditionally, CN has been used for a broad range of human ailments including snake bites and cancer. OBJECTIVES: This article compiles the ethnomedicinal uses of CN and its phytochemistry, and thus provides a phytochemical library of CN...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28192466/descriptive-study-of-plant-resources-in-the-context-of-the-ethnomedicinal-relevance-of-indigenous-flora-a-case-study-from-toli-peer-national-park-azad-jammu-and-kashmir-pakistan
#15
Muhammad Shoaib Amjad, Mirza Faisal Qaeem, Israr Ahmad, Sami Ullah Khan, Sunbal Khalil Chaudhari, Nafeesa Zahid Malik, Humaira Shaheen, Arshad Mehmood Khan
BACKGROUND: This paper presents the first quantitative ethnobotanical study of the flora in Toli Peer National Park of Azad Jammu and Kashmir, Pakistan. Being a remote area, there is a strong dependence by local people on ethnobotanical practices. Thus, we attempted to record the folk uses of the native plants of the area with a view to acknowledging and documenting the ethnobotanical knowledge. The aims of the study were to compile an inventory of the medicinal plants in the study area and to record the methods by which herbal drugs were prepared and administered...
2017: PloS One
https://www.readbyqxmd.com/read/28192202/ethnomedicinal-uses-of-plants-for-the-treatment-of-malaria-in-soon-valley-khushab-pakistan
#16
Amin Shah, Sarvat Rahim
ETHNOPHARMACOLOGICAL RELEVANCE: To best of our knowledge this is the first quantitative ethno-medicinal study with the aim of documenting the indigenous knowledge and practices of using plants for malarial therapy in Soon Valley, Khushab, Pakistan. In this Valley, malaria is among the major public health problems but, until now, the population still mostly relies on herbal medicine for treatment. MATERIALS AND METHODS: Ethno-medicinal data were documented from 63 informants by using semi-structured questionnaires and interviewing the informants about their knowledge of plants regarding malaria and related symptoms...
March 22, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28183236/antimalarial-antiplasmodial-and-analgesic-activities-of-root-extract-of-alchornea-laxiflora
#17
Jude E Okokon, Nkemnele Bensella Augustine, Dinesh Mohanakrishnan
CONTEXT: Alchornea laxiflora (Benth.) Pax. & Hoffman (Euphorbiaceae) root decoctions are traditionally used in the treatment of malaria and pain in Nigeria. OBJECTIVE: To assess the antimalarial, antiplasmodial and analgesic potentials of root extract and fractions against malarial infections and chemically-induced pains. MATERIAL AND METHODS: The root extract and fractions of Alchornea laxiflora were investigated for antimalarial activity against Plasmodium berghei infection in mice, antiplasmodial activity against chloroquine sensitive (Pf 3D7) and resistant (Pf INDO) strains of Plasmodium falciparum using SYBR green assay method and analgesic activity against experimentally-induced pain models...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28138372/ethnomedicinal-cichorium-intybus-seed-extracts-an-impending-preparation-against-multidrug-resistant-bacterial-pathogens
#18
Hazir Rahman, Usman Ali Khan, Muhammad Qasim, Noor Muhammad, Muhammad Daud Khan, Muhammad Asif, Azizullah Azizullah, Muhammad Adnan, Waheed Murad
BACKGROUND: The present study was undertaken to analyze the phytochemical content and biological activity of Cichorium intybus seeds traditionally used in Charsadda, Pakistan against multidrug resistant (MDR) bacterial pathogens. OBJECTIVES: This study explored the qualitative and quantitative antibacterial potential of C. intybus. Further qualitative analysis of phytochemical content was performed. METHODS: Cichorium intybus seed extracts were prepared in aqueous, chloroform, ethanol, and hexane separately...
November 2016: Jundishapur Journal of Microbiology
https://www.readbyqxmd.com/read/28134470/comprehensive-characterisation-of-n-alkylresorcinols-and-other-lipid-constituents-of-mercurialis-tomentosa-l-from-alicante-spain
#19
Peter Lorenz, Miriam Heinrich, Jürgen Conrad, Annerose Heller, Florian C Stintzing, Dietmar R Kammerer
Mercurialis tomentosa L. has been used in Spanish ethnomedicine. In the present study the first phytochemical characterisation of a lipid fraction from M. tomentosa was performed. The CHCl3 extraction of aerial parts from M. tomentosa and GC/MS investigations revealed the occurrence of cuticular lipid and wax constituents, like long chain n-alcohols and n-aldehydes (C22  - C30 ), besides several aromatic constituents, i.e., phenylpropanoids and n-alkylresorcinols. The latter were further purified by CC and analysed by LC/MS(n) ...
February 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28131912/healing-leishmaniasis-in-amazonia-review-of-ethnomedicinal-concepts-and-pharmaco-chemical-analysis-of-traditional-treatments-to-inspire-modern-phytotherapies
#20
REVIEW
Guillaume Odonne, Emeline Houël, Geneviève Bourdy, Didier Stien
ETHNOPHARMACOLOGICAL RELEVANCE: Cutaneous/mucocutaneous leishmaniasis are neglected tropical diseases occurring in all intertropical regions of the world. Amazonian populations developed an abundant knowledge related to the disease and its remedies. Therefore, we undertook to review traditional antileishmanial plants in Amazonia, and developed new tools to analyze this somewhat dispersed information. MATERIAL AND METHODS: A review of the literature concerning traditional remedies against cutaneous/mucocutaneous leishmaniasis in the Amazon was conducted, and the obtained data used for the calculation of distribution indexes designed to highlight the most relevant uses in Amazonia...
January 25, 2017: Journal of Ethnopharmacology
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