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Ethnopharmacology

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https://www.readbyqxmd.com/read/27916942/evidence-of-bioactive-compounds-from-vernonia-polyanthes-leaves-with-topical-anti-inflammatory-potential
#1
Kamilla C M Rodrigues, Lucas A Chibli, Bruna C S Santos, Vanessa S Temponi, Nícolas C C Pinto, Elita Scio, Glauciemar Del-Vechio-Vieira, Maria S Alves, Orlando V Sousa
Vernonia polyanthes Less. (Asteraceae), popularly known as "assa-peixe", is a plant species used in Brazilian traditional medicine for the treatment of cutaneous damage, cicatrization, inflammation, and rheumatism. Based on these ethnopharmacological findings, the current study evaluated the topical anti-inflammatory effects of the hexane (HEVP) and ethyl acetate (EAEVP) extracts from V. polyanthes leaves in experimental models of skin inflammation. Chemical characterization was carried out by HPLC-UV/DAD analysis...
December 1, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27916800/lead-discovery-strategies-for-identification-of-chlamydia-pneumoniae-inhibitors
#2
REVIEW
Leena Hanski, Pia Vuorela
Throughout its known history, the gram-negative bacterium Chlamydia pneumoniae has remained a challenging target for antibacterial chemotherapy and drug discovery. Owing to its well-known propensity for persistence and recent reports on antimicrobial resistence within closely related species, new approaches for targeting this ubiquitous human pathogen are urgently needed. In this review, we describe the strategies that have been successfully applied for the identification of nonconventional antichlamydial agents, including target-based and ligand-based virtual screening, ethnopharmacological approach and pharmacophore-based design of antimicrobial peptide-mimicking compounds...
November 28, 2016: Microorganisms
https://www.readbyqxmd.com/read/27905101/a-review-on-antiviral-activity-of-the-himalayan-medicinal-plants-traditionally-used-to-treat-bronchitis-and-related-symptoms
#3
REVIEW
Rahila Amber, Muhammad Adnan, Akash Tariq, Sakina Mussarat
OBJECTIVES: Bronchitis is a common respiratory tract infection of humans mainly caused by influenza virus, rhinovirus, adenovirus, coronavirus and respiratory syncytial virus. The aim of this review was to gather fragmented literature on ethnomedicinal plants used against bronchitis in the Himalayan region and their in-vitro validation against bronchitis causing viral pathogens. KEY FINDINGS: Present review contains ethnomedicines of total 55 plants from different countries of the Himalayas...
December 1, 2016: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/27891094/anti-acne-activity-of-italian-medicinal-plants-used-for-skin-infection
#4
Kate Nelson, James T Lyles, Tracy Li, Alessandro Saitta, Eugenia Addie-Noye, Paula Tyler, Cassandra L Quave
Propionibacterium acnes is implicated in the pathogenesis of acne vulgaris, which impacts >85% of teenagers. Novel therapies are in high demand and an ethnopharmacological approach to discovering new plant sources of anti-acne therapeutics could contribute to filling this void in effective therapies. The aims of our study were two-fold: (1) To determine if species identified in ethnopharmacological field studies as having traditional uses for skin and soft tissue infection (SSTI) exhibit significantly more activity against P...
2016: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/27846856/ethno-medicinal-survey-of-important-plants-practiced-by-indigenous-community-at-ladha-subdivision-south-waziristan-agency-pakistan
#5
Muhammad Abdul Aziz, Muhammad Adnan, Amir Hasan Khan, Atiq Ur Rehman, Rahmatullah Jan, Jafar Khan
BACKGROUND: Medicinal flora plays a vital role in treating various types of ailments in living beings. The present study was planned to investigate and document systematically the indigenous knowledge in a scientifically little explored area of Ladha sub-division, South Waziristan agency, Pakistan. Hence, this study would contribute positively to the field of ethnopharmacology. METHODS: Prior to ethnomedicinal data collection, regular field visits were conducted during the month of May and June 2015 to locate the sites and respondents from where the traditional knowledge was to be recorded...
November 15, 2016: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/27829842/the-role-of-anethum-graveolens-l-dill-in-the-management-of-diabetes
#6
REVIEW
Mohammad Taghi Goodarzi, Iraj Khodadadi, Heidar Tavilani, Ebrahim Abbasi Oshaghi
Aim. There is evidence that Anethum graveolens (AG) has been used for centuries in Asian traditional medicine, and its constituents have useful effects on the control and management of diabetes and cardiovascular disorders. AG has many useful effects, including hypolipidemic and hypoglycemic effects, and it has been reported to reduce the incidence of diabetic complications. It acts mainly by affecting antioxidant capacity and change in some genes in glucose and lipid pathways. The aim of the present paper was to summarize pharmacological effects of AG in the management of diabetes...
2016: Journal of Tropical Medicine
https://www.readbyqxmd.com/read/27816659/ethnopharmacological-appraisal-of-culturally-important-medicinal-plants-and-polyherbal-formulas-used-against-communicable-diseases-in-rodrigues-island
#7
Anne Kathie Samoisy, Fawzi Mahomoodally
ETHNOPHARMACOLOGICAL RELEVANCE: The tropical island of Rodrigues is one of three islands that constitute the Mascarene archipelago in the Indian Ocean. Currently considered as a biodiversity hotspot, the island has also a resilient history in the use of traditional medicine. However, there has been no ethnopharmacological study to document quantitatively such traditional practice against communicable diseases (CD), which currently accounts for 6.61% annual death and 30.7% attendances in public hospitals...
November 2, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27812652/screening-of-the-in-vitro-antileishmanial-activities-of-compounds-and-secondary-metabolites-isolated-from-maytenus-guianensis-klotzsch-ex-reissek-celastraceae-chichu%C3%A3-amazon
#8
Dionatas Ulises de Oliveira Meneguetti, Renato Abreu Lima, Fernanda Bay Hurtado, Guilherme Matos Passarini, Sharon Rose Aragão Macedo, Neuza Biguinati de Barros, Flávio Augusto de Souza Oliveira, Patrícia Soares de Maria de Medeiros, Júlio Sancho Linhares Teixeira Militão, Roberto Nicolete, Valdir Alves Facundo
INTRODUCTION: Maytenus guianensis is a member of the Celastraceae family that is used in traditional medicine, particularly for its anti-parasitic and anti-cancer effects. To explore the ethnopharmacological potential of this plant, the present study was designed to screen the in vitro antileishmanial activities of extracts and compounds isolated from M. guianensis. METHODS: Maytenus guianensis stems and leaves were extracted in acetone, followed by the preparation of eluates and isolation of secondary metabolites using chromatography on a glass column with silica gel as the fixed phase...
September 2016: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/27785446/scientometric-study-of-academic-publications-on-antioxidative-herbal-medicines-in-type-2-diabetes-mellitus
#9
Ozra Tabatabaei-Malazy, Amir Ramezani, Rasha Atlasi, Bagher Larijani, Mohammad Abdollahi
BACKGROUND: Scientometric analysis is increasingly used for research assessment. We aimed to perform a scientometric analysis of research productivity in field of antioxidative hypoglycemic herbal medicine and diabetes. METHODS: Some of search terms were "type 2 diabetes", "antioxidant", "herb", "phytotherapy", "ethnopharmacology", "Chinese medicine", "traditional medicine", in Scopus web databases until January 2015, and limited to human. The collected data were used to generate the specific features such as publication year, main journal in the field, citation, subject area, and co-authorship network of authors and institutes...
2016: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/27780135/structural-characterization-of-a-novel-derivative-of-myricetin-from-mimosa-pudica-as-an-anti-proliferative-agent-for-the-treatment-of-cancer
#10
Joby Jose, A T Dhanya, Karickal R Haridas, T M Sumesh Kumar, Sony Jayaraman, E Jayadevi Variyar, Sudheesh Sudhakaran
The study was initiated to determine the anticancer activity of a novel compound isolated from the plant Mimosa pudica. The structure of the compound was identified as a derivative of myricetin having alkyl, hydroxy alkyl and methyl substitutions on the basis of spectral evidences (UV-vis, FT-IR, (1)H NMR and Mass spectra). The isolated compound was interpreted as 2-(2',6'-dimethyl-3',4',5'-alkyl or hydroxy alkyl substituted phenyl)-3-oxy-(alkyl or hydoxy alkyl)- 5,7-dihydroxy-chromen-4-one. In vitro evaluation of anticancer activity against human lung adenocarcinoma cell line (A549) and human erythroleukemic cell line (K562) were conducted using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay...
October 22, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27774245/patenting-nature-or-protecting-culture-ethnopharmacology-and-indigenous-intellectual-property-rights
#11
Ian Vincent McGonigle
Ethnopharmacologists are scientists and anthropologists that study indigenous medicines and healing practices, and who often develop new therapies and medicines for wider use. Ethnopharmacologists do fieldwork with indigenous peoples in traditional societies, where they encounter a wide range of cultural values and varying ideas about the nature of property relations. This poses difficulties for protecting indigenous intellectual property and for making just trade agreements. This Note reviews the legal issues relevant to the protection of indigenous resources in ethnopharmacology trade agreements, and suggests that recent developments in anthropology and the social study of science could be instructive in furthering the legal discourse and in providing policy directions...
April 2016: Journal of Law and the Biosciences
https://www.readbyqxmd.com/read/27773803/the-genus-boschniakia-in-china-an-ethnopharmacological-and-phytochemical-review
#12
Le Zhang, Yunshan Zhao, Zhipeng A Wang, Kunhua Wei, Bin Qiu, Chunhong Zhang, QiYan Wang-Müller, Minhui Li
ETHNOPHARMACOLOGICAL RELEVANCE: As a group of important medicine plants, Boschniakia rossica (Cham. et Schltdl) Fedtsch. and B. himalaica Hook.f.et Thoms, which are the only two species in the genus Boschniakia (Orobanchaceae), have long been used in traditional Chinese medicine for their multiple therapeutic uses related to enhanced renal function, erectile dysfunction, defaecate and hepatoprotective. Additionally, the two species are also used as dietary supplements in wine, cosmetics, and other healthy food...
October 20, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27765608/influence-of-geography-seasons-and-pedology-on-chemical-composition-and-anti-inflammatory-activities-of-essential-oils-from-lippia-multiflora-mold-leaves
#13
Lêniféré Chantal Soro, Sylvie Munier, Yves Pelissier, Lidwine Grosmaire, Rickey Yada, David Kitts, Anin Louise Ocho-Anin Atchibri, Caroline Guzman, Frédéric Boudard, Chantal Menut, Jean Charles Robinson, Patrick Poucheret
ETHNOPHARMACOLOGICAL RELEVANCE: Lippia multiflora is a plant with nutritional and pharmaco-therapeutic properties that is native to central and occidental Africa. The potential effects of plants on health are associated with their chemical composition. Therefore, the present study aimed to identify chemical variations in essential oils of Lippia multiflora as a function of geographic origin and time of annual harvest to determine optimal chemical profiles for ethno-pharmacotherapeutic applications...
October 17, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27747213/dereplication-of-natural-products-using-gc-tof-mass-spectrometry-improved-metabolite-identification-by-spectral-deconvolution-ratio-analysis
#14
Fausto Carnevale Neto, Alan C Pilon, Denise M Selegato, Rafael T Freire, Haiwei Gu, Daniel Raftery, Norberto P Lopes, Ian Castro-Gamboa
Dereplication based on hyphenated techniques has been extensively applied in plant metabolomics, thereby avoiding re-isolation of known natural products. However, due to the complex nature of biological samples and their large concentration range, dereplication requires the use of chemometric tools to comprehensively extract information from the acquired data. In this work we developed a reliable GC-MS-based method for the identification of non-targeted plant metabolites by combining the Ratio Analysis of Mass Spectrometry deconvolution tool (RAMSY) with Automated Mass Spectral Deconvolution and Identification System software (AMDIS)...
2016: Frontiers in Molecular Biosciences
https://www.readbyqxmd.com/read/27737817/isolation-characterization-and-quantification-of-an-anxiolytic-constituent-mahanimbine-from-murraya-koenigii-linn-spreng-leaves
#15
Jyoti Dahiya, Jitender Singh, Ashwani Kumar, Anupam Sharma
ETHNOPHARMACOLOGICAL RELEVANCE: Leaves of M. koenigii Linn. Spreng (Rutaceae) have been used as traditional medicine for anxiety disorders. Aim of the study was to isolate antianxiety principle(s) from the leaves of M. koenigii using bioactivity guided approach. MATERIAL AND METHODS: Hydroalcoholic extract of M. koenigii leaves was prepared using soxhlet apparatus, and the same was evaluated for antianxiety activity at 250, 500 and 750mg/kg, po, using Elevated plus-maze (EPM)...
October 10, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27721053/piper-betle-and-its-bioactive-metabolite-phytol-mitigates-quorum-sensing-mediated-virulence-factors-and-biofilm-of-nosocomial-pathogen-serratia-marcescens-in-vitro
#16
Ramanathan Srinivasan, Kannan Rama Devi, Arunachalam Kannappan, Shunmugiah Karutha Pandian, Arumugam Veera Ravi
ETHNOPHARMACOLOGICAL RELEVANCE: Piper betle, a tropical creeper plant belongs to the family Piperaceae. The leaves of this plant have been well known for their therapeutic, religious and ceremonial value in South and Southeast Asia. It has also been reported to possess several biological activities including antimicrobial, antioxidant, antinociceptive, antidiabetic, insecticidal and gastroprotective activities and used as a common ingredient in indigenous medicines. In Indian system of ayurvedic medicine, P...
October 6, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27716305/health-seeking-behavior-and-use-of-medicinal-plants-among-the-hamer-ethnic-group-south-omo-zone-southwestern-ethiopia
#17
Biniam Paulos, Teferi Gedif Fenta, Daniel Bisrat, Kaleab Asres
BACKGROUND: Health seeking behavior of people around the globe is affected by different socio-cultural and economic factors. In Ethiopia, people living in rural areas in particular, are noted for their use of medicinal plants as a major component of their health care option. This study was conducted to document ethnopharmacological information of the Hamer semi-pastoralists ethnic group in southwestern Ethiopia. METHODS: A cross-sectional study was carried out whereby information on demographic characteristics, prevalence of perceived illnesses, factors associated with preference of health care seeking options, medicinal plants used and hoarded as well as some healers' socio-economic characteristics were collected using two sets of semi-structured questionnaires - one for household (HH) heads and the other for traditional healers supplemented by focus group discussions (FGDs)...
October 6, 2016: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/27703356/nine-traditional-chinese-herbal-formulas-for-the-treatment-of-depression-an-ethnopharmacology-phytochemistry-and-pharmacology-review
#18
Dan-Dan Feng, Tao Tang, Xiang-Ping Lin, Zhao-Yu Yang, Shu Yang, Zi-An Xia, Yun Wang, Piao Zheng, Yang Wang, Chun-Hu Zhang
Depression is a major mental disorder, and is currently recognized as the second-leading cause of disability worldwide. However, the therapeutic effect of antidepressants remains unsatisfactory. For centuries, Chinese herbal formulas (CHFs) have been widely used in the treatment of depression, achieving better therapeutic effects than placebo and having fewer side effects than conventional antidepressants. Here, we review the ethnopharmacology, phytochemistry, and pharmacology studies of nine common CHFs: "banxia houpo" decoction, "chaihu shugansan", "ganmaidazao" decoction, "kaixinsan", "shuganjieyu" capsules, "sinisan", "wuling" capsules, "xiaoyaosan", and "yueju"...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27692335/thymus-vulgaris-l-essential-oil-and-its-main-component-thymol-anthelmintic-effects-against-haemonchus-contortus-from-sheep
#19
Luis E Ferreira, Bruno I Benincasa, Ana L Fachin, Suzelei C França, Silvia S H T Contini, Ana C S Chagas, Rene O Beleboni
Haemonchus contortus is an important gastrointestinal parasite on sheep farms in tropical regions. The resistance of the parasite against most anthelmintic drugs represents a great economic problem to sheep farming and is a major challenge that needs to be overcome. The searches for new anthelmintic agents that act on different stages of the parasite's life cycle are necessary for the development of new therapeutic options. The aim of this study was to evaluate the in vitro and in vivo anthelmintic activity of Thymus vulgaris essential oil against H...
September 15, 2016: Veterinary Parasitology
https://www.readbyqxmd.com/read/27686269/phytochemical-and-ethnomedicinal-study-of-huperzia-species-used-in-the-traditional-medicine-of-saraguros-in-southern-ecuador-ache-and-mao-inhibitory-activity
#20
Chabaco Armijos, Gianluca Gilardoni, Luis Amay, Antonio Lozano, Francesco Bracco, Jorge Ramirez, Nicole Bec, Christian Larroque, Paola Vita Finzi, Giovanni Vidari
ETHNOBOTANICAL AND ETHNOMEDICINAL RELEVANCE: This study concerns seven Huperzia species (Lycopodiaceae), namely H. brevifolia, H. columnaris, H. compacta, H. crassa, H. espinosana, H. tetragona, H. weberbaueri, which are considered sacred plants by the Saraguro community, living in the Southern Andes of Ecuador; these plants are widely used in traditional medicine and ritual ceremonies. MATERIAL AND METHODS: The plants were selected on the basis of written interviews with 10 visionary healers (yachak) (2 women, 8 men), indicated as the most credible by the Saraguro Healers Council...
September 26, 2016: Journal of Ethnopharmacology
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