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https://www.readbyqxmd.com/read/29651928/rural-postpartum-women-with-substance-use-disorders
#1
Debra Kramlich, Rebecca Kronk, Lenora Marcellus, Alison Colbert, Karen Jakub
The incidence of perinatal opioid use and neonatal withdrawal continues to rise rapidly in the face of the growing opioid addiction epidemic in the United States, with rural areas more severely affected. Despite decades of research and development of practice guidelines, maternal and neonatal outcomes have not improved substantially. This focused ethnography sought to understand the experience of accessing care necessary for substance use disorder recovery, pregnancy, and parenting. Personal accounts of 13 rural women, supplemented by participant observation and media artifacts, uncovered three domains with underlying themes: challenges of getting treatment and care (service availability, distance/geographic location, transportation, provider collaboration/coordination, physical and emotional safety), opportunities to bond (proximity, information), and importance of relationships (respect, empathy, familiarity, inclusion, interactions with care providers)...
April 1, 2018: Qualitative Health Research
https://www.readbyqxmd.com/read/29651507/efficacy-and-side-effects-of-baclofen-and-the-novel-gaba-b-receptor-positive-allosteric-modulator-cmppe-in-animal-models-for-alcohol-and-cocaine-addiction
#2
Valentina Vengeliene, Tatiane T Takahashi, Olga A Dravolina, Irina Belozertseva, Edwin Zvartau, Anton Y Bespalov, Rainer Spanagel
RATIONALE: Preclinical studies suggest that the GABAB receptor is a potential target for treatment of substance use disorders. However, recent clinical trials report adverse effects in patients treated with the GABAB receptor agonist baclofen and even question efficacy. How can the discrepancy between preclinical and clinical findings be explained? OBJECTIVE: To test efficacy and adverse effects of baclofen and the novel GABAB positive allosteric modulator (PAM) CMPPE in rat addiction models, which were developed in accordance with DSM...
April 12, 2018: Psychopharmacology
https://www.readbyqxmd.com/read/29651257/mindfulness-based-interventions-for-the-treatment-of-substance-and-behavioral-addictions-a-systematic-review
#3
Marta Sancho, Marta De Gracia, Rita C Rodríguez, Núria Mallorquí-Bagué, Jéssica Sánchez-González, Joan Trujols, Isabel Sánchez, Susana Jiménez-Murcia, Jose M Menchón
Background: Emotion (dys)regulation as well as the interventions for improving these difficulties are receiving a growing attention in the literature. The aim of the present paper was to conduct a systematic review about the efficacy of mindfulness-based interventions (MBIs) in both substance and behavioral addictions (BAs). Method: A literature search was conducted using Cochrane, PubMed, and Web of Science. Fifty-four randomized controlled trials published in English since 2009 to April 2017 were included into a narrative synthesis...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29649120/what-is-the-evidence-for-food-addiction-a-systematic-review
#4
REVIEW
Eliza L Gordon, Aviva H Ariel-Donges, Viviana Bauman, Lisa J Merlo
The diagnostic construct of "food addiction" is a highly controversial subject. The current systematic review is the first to evaluate empirical studies examining the construct of "food addiction" in humans and animals. Studies were included if they were quantitative, peer-reviewed, and in the English language. The 52 identified studies (35 articles) were qualitatively assessed to determine the extent to which their findings indicated the following addiction characteristics in relation to food: brain reward dysfunction, preoccupation, risky use, impaired control, tolerance/withdrawal, social impairment, chronicity, and relapse...
April 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29648844/acceptability-of-nonabstinent-treatment-outcome-goals-among-addiction-treatment-providers-in-ukraine
#5
Alan K Davis, Tetiana Nickelsen, Robert A Zucker, Erin E Bonar, Maureen A Walton
We examined whether acceptability of nonabstinence treatment outcome goals varied as a function of a patient's severity of diagnosis (ICD-10 harmful use vs. dependence syndrome; World Health Organization, 1992), finality of outcome goal (intermediate vs. final), and type of substance (e.g., tobacco, alcohol, cannabis), among addiction treatment providers in Ukraine. We surveyed 44% of Ukrainian treatment providers (n = 446/1023; Mage = 40.4, SD = 8.6; Male = 67%; MYears Of Experience = 10.2, SD = 7.2). For tobacco use, most respondents (78%-93%) rated nonabstinence as acceptable, regardless of diagnostic severity or finality of outcome goal (i...
April 12, 2018: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
https://www.readbyqxmd.com/read/29642723/impulsivity-traits-and-addiction-related-behaviors-in-youth
#6
Kristine Rømer Thomsen, Mette Buhl Callesen, Morten Hesse, Timo Lehmann Kvamme, Michael Mulbjerg Pedersen, Mads Uffe Pedersen, Valerie Voon
Background and aims Impulsivity is a risk factor for addictive behaviors. The UPPS-P impulsivity model has been associated with substance addiction and gambling disorder, but its role in other non-substance addiction-related behaviors is less understood. We sought to examine associations between UPPS-P impulsivity traits and indicators of multiple substance and non-substance addiction-related behaviors in youth with varying involvement in these behaviors. Methods Participants (N = 109, aged 16-26 years, 69% males) were selected from a national survey based on their level of externalizing problems to achieve a broad distribution of involvement in addiction-related behaviors...
April 12, 2018: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/29642450/mechanistic-insights-into-the-stimulant-properties-of-novel-psychoactive-substances-nps-and-their-discrimination-by-the-dopamine-transporter-in-silico-and-in-vitro-exploration-of-dissociative-diarylethylamines
#7
Michelle A Sahai, Colin Davidson, Neelakshi Dutta, Jolanta Opacka-Juffry
Novel psychoactive substances (NPS) may have unsuspected addiction potential through possessing stimulant properties. Stimulants normally act at the dopamine transporter (DAT) and thus increase dopamine (DA) availability in the brain, including nucleus accumbens, within the reward and addiction pathway. This paper aims to assess DAT responses to dissociative diarylethylamine NPS by means of in vitro and in silico approaches. We compared diphenidine (DPH) and 2-methoxydiphenidine (methoxphenidine, 2-MXP/MXP) for their binding to rat DAT, using autoradiography assessment of [125 I]RTI-121 displacement in rat striatal sections...
April 7, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29628018/barriers-and-facilitators-affecting-the-implementation-of-substance-use-screening-in-primary-care-clinics-a-qualitative-study-of-patients-providers-and-staff
#8
Jennifer McNeely, Pritika C Kumar, Traci Rieckmann, Erica Sedlander, Sarah Farkas, Christine Chollak, Joseph L Kannry, Aida Vega, Eva A Waite, Lauren A Peccoralo, Richard N Rosenthal, Dennis McCarty, John Rotrosen
BACKGROUND: Alcohol and drug use are leading causes of morbidity and mortality that frequently go unidentified in medical settings. As part of a multi-phase study to implement electronic health record-integrated substance use screening in primary care clinics, we interviewed key clinical stakeholders to identify current substance use screening practices, barriers to screening, and recommendations for its implementation. METHODS: Focus groups and individual interviews were conducted with 67 stakeholders, including patients, primary care providers (faculty and resident physicians), nurses, and medical assistants, in two urban academic health systems...
April 9, 2018: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/29627964/evaluating-concurrent-validity-of-criminal-justice-and-clinical-assessments-among-women-on-probation
#9
Camila D Odio, Megan Carroll, Susan Glass, Ashley Bauman, Faye S Taxman, Jaimie P Meyer
BACKGROUND: Women in the criminal justice (CJ) system experience complex and comorbid medical, psychiatric, and substance use disorders, which often contribute to CJ involvement. To identify intersections between CJ and health needs, we calculated Spearman r correlations between concurrent CJ and clinical assessments from women on probation in Connecticut who were enrolled in a clinical trial. We examined longitudinal trends in CJ risk scores over 9 years of observation (2005-2014), modeling time to probation recidivism with shared gamma frailty models and comparing contiguous time points by Wilcoxon matched-pairs signed rank tests...
April 7, 2018: Health & Justice
https://www.readbyqxmd.com/read/29626778/a-longitudinal-study-of-risk-perceptions-and-e-cigarette-initiation-among-college-students-interactions-with-smoking-status
#10
Maria Cooper, Alexandra Loukas, Kathleen R Case, C Nathan Marti, Cheryl L Perry
BACKGROUND: Recent data suggest that lower perceived risks of e-cigarettes are associated with e-cigarette use in young adults; however, the temporality of this relationship is not well-understood. We explore how perceptions of harmfulness and addictiveness of e-cigarettes influence e-cigarette initiation, and specifically whether this association varies by cigarette smoking status, in a longitudinal study of tobacco use on college campuses. METHODS: Data are from a 5-wave 24-college study in Texas...
January 31, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29617709/what-happens-after-treatment-long-term-effects-of-continued-substance-use-psychiatric-problems-and-help-seeking-on-social-status-of-alcohol-dependent-individuals
#11
Katherine J Karriker-Jaffe, Jane Witbrodt, Meenakshi S Subbaraman, Lee Ann Kaskutas
Purpose: We examined whether alcohol-dependent individuals with sustained substance use or psychiatric problems after completing treatment were more likely to experience low social status and whether continued help-seeking would improve outcomes. Short summary: Ongoing alcohol, drug and psychiatric problems after completing treatment were associated with increased odds of low social status (unemployment, unstable housing and/or living in high-poverty neighborhood) over 7 years...
March 30, 2018: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/29617325/recent-advances-in-attention-bias-modification-for-substance-addictions
#12
Melvyn Weibin Zhang, Jiang Bo Ying, Guo Song, Daniel S S Fung, Helen E Smith
Research on attentional bias modification has increased since 2014. A recent meta-analysis demonstrates evidence for bias modification for substance disorders, including alcohol and tobacco use disorders. Several pharmacological trials have shown that pharmacological agents can attenuate and modify such attentional bias. The pharmacological trials that have appeared to date have produced mixed results, which has clinical implications. Developments in Internet and mobile technologies have transformed how attention bias modification is currently being achieved...
April 4, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29613999/exercise-reduces-dopamine-d1r-and-increases-d2r-in-rats-implications-for-addiction
#13
Lisa S Robison, Sabrina Swenson, John Hamilton, Panayotis K Thanos
INTRODUCTION: Exercise has been shown to be effective for preventing and treating substance abuse in both clinical and preclinical studies. Less is known, however, regarding the underlying neurobiological mechanisms driving these changes in drug-seeking behavior. One possibility is that exercise may alter the mesolimbic dopamine pathway in such a way that makes drugs of abuse less salient and/or rewarding. METHODS: To examine possible exercise-induced changes in dopamine signaling, male and female Lewis rats were split into exercise and sedentary groups at 8 weeks of age...
April 2, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29609132/the-self-report-habit-index-assessing-habitual-marijuana-alcohol-e-cigarette-and-cigarette-use
#14
Meghan E Morean, Kelly S DeMartini, Dawn Foster, Julie Patock-Peckham, Kathleen A Garrison, Philip R Corlett, John H Krystal, Suchitra Krishan-Sarin, Stephanie S O'Malley
BACKGROUND: Substance use is partially driven by habitual processes that occur automatically in response to environmental cues and may be central to users' identities. This study was designed to validate the Self-Report Habit Index (SRHI) for assessing habitual marijuana, alcohol, cigarette, and e-cigarette use. METHODS: We examined the SRHI's psychometrics in separate samples of adult marijuana (Ns = 189;170), alcohol (Ns = 100;133), cigarette (Ns = 58;371), and e-cigarette (N = 239) users...
March 13, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29608428/is-ayahuasca-an-option-for-the-treatment-of-crack-cocaine-dependence
#15
Joselaine Ida Cruz, Solange Aparecida Nappo
The low efficacy of crack cocaine addiction treatment available in Brazil has led Brazilian users to find alternatives to reduce drug consumption or even to reach abstinence. One of them is the use of entheogenic substances, like ayahuasca, an infusion obtained from two native plant species from the Amazon. The present report aimed to understand how crack cocaine users recover from drug addiction by consuming ayahuasca tea in a religious context. This is a qualitative study with a purposeful sample of 40 crack cocaine users, based on in-depth, semi-structured interviews...
April 2, 2018: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/29608409/changes-in-withdrawal-and-craving-scores-in-participants-undergoing-opioid-detoxification-utilizing-ibogaine
#16
Benjamin J Malcolm, Martin Polanco, Joseph P Barsuglia
Opioid use disorder (OUD) is currently an epidemic in the United States (US) and ibogaine is reported to have the ability to interrupt opioid addiction by simultaneously mitigating withdrawal and craving symptoms. This study examined opioid withdrawal and drug craving scores in 50 participants with OUD undergoing a week-long detoxification treatment protocol with ibogaine. The Addiction Severity Index (ASI) was used for baseline characterization of participants' OUD. Clinical Opioid Withdrawal Scale (COWS), Subjective Opioid Withdrawal Scale (SOWS), and Brief Substance Craving Scale (BSCS) scores were collected at 48 and 24 hours prior to ibogaine administration, as well as 24 and 48 hours after ibogaine administration...
April 2, 2018: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/29606226/a-pilot-study-of-a-smartphone-application-supporting-recovery-from-drug-addiction
#17
Di Liang, Hui Han, Jiang Du, Min Zhao, Yih-Ing Hser
BACKGROUND: Mobile health (mHealth) technologies have the potential to facilitate self-monitoring and self-management for individuals with substance use disorders (SUD). S-Health is a bilingual smartphone application based on cognitive behavioral principles and is designed to support recovery from drug addiction by trigger recognition so as to allow practice in-the-moment coping to prevent relapse. METHOD: For this pilot randomized controlled study, 75 participants were recruited from methadone maintenance treatment clinics and the social worker consortium in Shanghai, China...
May 2018: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29606223/a-longitudinal-study-of-the-comparative-efficacy-of-women-for-sobriety-lifering-smart-recovery-and-12-step-groups-for-those-with-aud
#18
Sarah E Zemore, Camillia Lui, Amy Mericle, Jordana Hemberg, Lee Ann Kaskutas
BACKGROUND: Despite the effectiveness of 12-step groups, most people reporting a prior alcohol use disorder (AUD) do not sustain involvement in such groups at beneficial levels. This highlights the need for research on other mutual help groups that address alcohol problems and may attract those who avoid 12-step groups. The current study addresses this need, offering outcome data from the first longitudinal, comparative study of 12-step groups and their alternatives: The Peer ALlternatives for Addiction (PAL) Study...
May 2018: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29606034/internet-gaming-disorder-an-emergent-health-issue-for-men
#19
Kevin H Chen, John L Oliffe, Mary T Kelly
Internet gaming is a legitimate leisure activity worldwide; however, there are emerging concerns that vast numbers of gamers are becoming addicted. In 2013, the American Psychiatric Association (APA) classified Internet Gaming Disorder (IGD) as a condition warranting more clinical research ahead of formalizing it as a mental disorder. Proposed as a behavioral addiction, IGD shares many similarities in both physical and psychosocial manifestations with substance use disorder, including cerebral changes on functional magnetic resonance imaging (fMRI)...
March 1, 2018: American Journal of Men's Health
https://www.readbyqxmd.com/read/29601307/applying-american-society-of-addiction-medicine-performance-measures-in-commercial-health-insurance-and-services-data
#20
Cindy Parks Thomas, Grant A Ritter, Alex H S Harris, Deborah W Garnick, Kenneth I Freedman, Barbara Herbert
OBJECTIVES: ASAM's Standards of Care for the Addiction Specialist established appropriate care for the treatment of substance use disorders. ASAM identified three high priority performance measures for specification and testing for feasibility in various systems using administrative claims: use of pharmacotherapy for alcohol use disorder (AUD); use of pharmacotherapy for opioid use disorder (OUD); and continuity of care after withdrawal management services. This study adds to the initial testing of these measures in the Veteran's Health Administration (VHA) by testing the feasibility of specifications in commercial insurance data (Cigna)...
March 29, 2018: Journal of Addiction Medicine
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