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Veterinary pathology

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https://www.readbyqxmd.com/read/29455473/comparison-between-magnetic-resonance-imaging-computed-tomography-and-arthrography-to-identify-artificially-induced-cartilage-defects-of-the-equine-carpal-joints
#1
José Suarez Sanchez-Andrade, Henning Richter, Karolin Kuhn, Andrea S Bischofberger, Patrick R Kircher, Séamus Hoey
While articular cartilage changes are considered to be one of the initial events in the pathological cascade leading to osteoarthritis, these changes remain difficult to detect using conventional diagnostic imaging modalities such as plain radiography. The aim of this prospective, experimental, methods comparison study was to compare the sensitivity of magnetic resonance imaging (MRI), magnetic resonance arthrography, computed tomography (CT), and CT arthrography in the detection of artificially induced articular cartilage defects in the equine carpal joints...
February 18, 2018: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/29447808/hold-your-horses-a-comparison-of-human-laryngomalacia-with-analogous-equine-airway-pathology
#2
REVIEW
Rachael J Lawrence, Matthew J Butterell, James D Constable, Matija Daniel
OBJECTIVES: Laryngomalacia is the most common cause of stridor in infants. Dynamic airway collapse is also a well-recognised entity in horses and an important cause of surgical veterinary intervention. We compare the aetiology, clinical features and management of human laryngomalacia with equine dynamic airway collapse. METHODS: A structured review of the PubMed, the Ovid Medline and the Cochrane Collaboration databases (Cochrane Central Register of Controlled Trials, Cochrane Database of Systemic Reviews)...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29446181/51st-annual-conference-of-physiology-and-pathology-of-reproduction-and-43rd-mutual-conference-of-veterinary-and-human-reproductive-medicine-hannover-21st-23rd-of-february-2018-51-jahrestagung-physiologie-und-pathologie-der-fortpflanzung-und-43-veterin%C3%A3-r-humanmedizinische
#3
https://www.readbyqxmd.com/read/29426475/eulimdana-clava-nematoda-filarioidea-infection-in-domestic-pigeons-columba-livia-domestica-molecular-characterization-and-pathological-changes
#4
Jovana Šupić, Alma Šeho Alić, Melida Hasanić, Šejla Goletić, Georg G Duscher, Adnan Hodžić, Amer Alić
Filarial nematodes of the Eulimdana genus inhabit subcutaneous tissue of various avian species, mostly Charadriiforme birds. In domestic pigeons, E. clava is the only species recorded in the subcutaneous tissue in a number of isolated cases. In the present study, we discuss the morphology and histopathology of filarial nematodes recovered from subcutaneous tissue of domestic pigeons in Bosnia and Herzegovina. In total 110 pigeons were submitted to necropsy at the Department of Pathology of the Faculty of Veterinary Medicine in Sarajevo...
February 15, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29424062/abrogation-of-fluid-suppression-in-intracranial-postcontrast-fluid-attenuated-inversion-recovery-magnetic-resonance-imaging-a-clinical-and-phantom-study
#5
Peter J Dickinson, Sarah Jones-Woods, Derek D Cissell
Postcontrast, fluid-attenuated inversion recovery (FLAIR) sequences are reported to be of variable value in veterinary and human neuroimaging. The source of hyperintensity in postcontrast-T2 FLAIR images is inconsistently reported and has implications for the significance of imaging findings. We hypothesized that the main source of increased signal intensity in postcontrast-T2 FLAIR images would be due to gadolinium leakage into adjacent fluid, and that the resulting gadolinium-induced T1 shortening causes reappearance of fluid hyperintensity, previously nulled on precontrast FLAIR images...
February 8, 2018: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/29421480/advanced-nutritional-and-stem-cells-approaches-to-prevent-equine-metabolic-syndrome
#6
REVIEW
Krzysztof Marycz, Izabela Michalak, Katarzyna Kornicka
Horses metabolic disorders have become an important problem of modern veterinary medicine. Pathological obesity, insulin resistance and predisposition toward laminitis are associated with Equine Metabolic Syndrome (EMS). Based on pathogenesis of EMS, dietary and cell therapy management may significantly reduce development of that disorder. Special attention has been paid to the diet supplementation with high bioavailability minerals and mesenchymal stem cells (MSC) which increase insulin sensitivity. In nutrition, there is a great interests in natural algae enriched in biosorption process with micro and macroelements...
January 31, 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29402206/validation-of-digital-microscopy-compared-with-light-microscopy-for-the-diagnosis-of-canine-cutaneous-tumors
#7
Christof A Bertram, Corinne Gurtner, Martina Dettwiler, Olivia Kershaw, Kristina Dietert, Laura Pieper, Hannah Pischon, Achim D Gruber, Robert Klopfleisch
Integration of new technologies, such as digital microscopy, into a highly standardized laboratory routine requires the validation of its performance in terms of reliability, specificity, and sensitivity. However, a validation study of digital microscopy is currently lacking in veterinary pathology. The aim of the current study was to validate the usability of digital microscopy in terms of diagnostic accuracy, speed, and confidence for diagnosing and differentiating common canine cutaneous tumor types and to compare it to classical light microscopy...
January 1, 2018: Veterinary Pathology
https://www.readbyqxmd.com/read/29379689/molecular-and-serological-dynamics-of-chlamydia-pecorum-infection-in-a-longitudinal-study-of-prime-lamb-production
#8
Sankhya Bommana, Evelyn Walker, Marion Desclozeaux, Martina Jelocnik, Peter Timms, Adam Polkinghorne, Scott Carver
Background: Chlamydia pecorum is a globally significant livestock pathogen causing pathology and production losses. The on-farm infection and serological dynamics and the relevance of existing diagnostic tools for diagnosing C. pecorum in livestock remains poorly characterized. In this study, we characterized the antigen and antibody dynamics of this pathogen in a longitudinal study of prime lamb production, utilizing the infection focused C. pecorum-specific 16S rRNA qPCR assay and serology based chlamydial Complement fixation Test (CFT)...
2018: PeerJ
https://www.readbyqxmd.com/read/29378221/canine-sarcomas-as-a-surrogate-for-the-human-disease
#9
REVIEW
Daniel L Gustafson, Dawn L Duval, Daniel P Regan, Douglas H Thamm
Pet dogs are becoming increasingly recognized as a population with the potential to inform medical research through their treatment for a variety of maladies by veterinary health professionals. This is the basis of the One Health initiative, supporting the idea of collaboration between human and animal health researchers and clinicians to study spontaneous disease processes and treatment in animals to inform human health. Cancer is a major health burden in pet dogs, accounting for approximately 30% of deaths across breeds...
January 26, 2018: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29345551/quantifying-novice-and-expert-differences-in-visual-diagnostic-reasoning-in-veterinary-pathology-using-eye-tracking-technology
#10
Amy L Warren, Tyrone L Donnon, Catherine R Wagg, Heather Priest, Nicole J Fernandez
Visual diagnostic reasoning is the cognitive process by which pathologists reach a diagnosis based on visual stimuli (cytologic, histopathologic, or gross imagery). Currently, there is little to no literature examining visual reasoning in veterinary pathology. The objective of the study was to use eye tracking to establish baseline quantitative and qualitative differences between the visual reasoning processes of novice and expert veterinary pathologists viewing cytology specimens. Novice and expert participants were each shown 10 cytology images and asked to formulate a diagnosis while wearing eye-tracking equipment (10 slides) and while concurrently verbalizing their thought processes using the think-aloud protocol (5 slides)...
January 18, 2018: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/29344980/analytical-validation-of-a-new-point-of-care-assay-for-serum-amyloid-a-in-horses
#11
D Schwartz, N Pusterla, S Jacobsen, M M Christopher
BACKGROUND: Serum amyloid A (SAA) is a major acute phase protein in horses. A new point-of-care (POC) test for SAA (Stablelab) is available, but studies evaluating its analytical accuracy are lacking. OBJECTIVES: Evaluate the analytical performance of the SAA POC test by: (1) determining linearity and imprecision, (2) comparing results in whole blood with those in serum or plasma, and (3) comparing POC results with those obtained using a previously validated turbidimetric immunoassay (TIA)...
January 17, 2018: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29344477/is-there-an-increased-prevalence-of-asteroid-hyalosis-in-eyes-with-uveal-melanoma-a-histopathologic-study
#12
EDITORIAL
Christopher K H Burris, Amir A Azari, Mozhgan R Kanavi, Richard R Dubielzig, Vivian Lee, Justin L Gottlieb, Heather D Potter, Kyungmann Kim, Meisha L Raven, Maria E Rodriguez, Devasis N Reddy, Daniel M Albert
During the planning meeting for the Collaborative Ocular Melanoma Study (COMS) prior to the start of patient recruitment in 1986, there was an interest expressed in determining whether a relationship existed between the presence of uveal melanoma (UM) and asteroid hyalosis (AH). To answer this question, the ophthalmic examination form (unlike the pathology form for enucleated eyes) for each COMS patient asked whether AH was present or not. Though an increased prevalence was not found, this result was never published...
November 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29307125/the-concordance-between-endoscopic-and-histological-diagnosis-in-114-dogs-affected-by-gastric-disease
#13
Maria Chiara Marchesi, Cecilia Carlotta Timpano, Sara Busechian, Camillo Pieramati, Fabrizio Rueca
Endoscopy is a common, minimally invasive diagnostic technique that can be used to observe internal organs, e.g. the stomach, and to obtain mucosal bioptic samples for histo pathological examination. The aim of this study was to analyse the concordance between endoscopic and histological evaluation of gastric diseases in dogs. One hundred twenty-nine medical records of dogs undergoing gastroscopy have been received and stored by the Veterinary Hospital of Perugia University (Perugia, Italy) between 2009-2012...
December 29, 2017: Veterinaria Italiana
https://www.readbyqxmd.com/read/29276322/rhesus-macaques-macaca-mulatta-displaying-self-injurious-behavior-show-more-sleep-disruption-than-controls
#14
Lauren L Stanwicks, Amanda F Hamel, Melinda A Novak
Self-injurious behavior (SIB) is a pathology observed in both humans and animals. In humans, SIB has been linked to various mental health conditions that are also associated with significant sleep disruption. In rhesus macaques, SIB consists of self-directed biting which can range from mild skin abrasions to wounds requiring veterinary care. However, only one study suggests possible sleep disruption in macaques with SIB. We evaluated sleep disruption using a noninvasive system (infra-red camera and a video surveillance program) which created videos for every movement over the nighttime hours...
December 2017: Applied Animal Behaviour Science
https://www.readbyqxmd.com/read/29261747/sex-specific-reference-intervals-of-hematologic-and-biochemical-analytes-in-sprague-dawley-rats-using-the-nonparametric-rank-percentile-method
#15
Qili He, Guoming Su, Keliang Liu, Fangcheng Zhang, Yong Jiang, Jun Gao, Lida Liu, Zhongren Jiang, Minwu Jin, Huiping Xie
BACKGROUND: Hematologic and biochemical analytes of Sprague-Dawley rats are commonly used to determine effects that were induced by treatment and to evaluate organ dysfunction in toxicological safety assessments, but reference intervals have not been well established for these analytes. Reference intervals as presently defined for these analytes in Sprague-Dawley rats have not used internationally recommended statistical method nor stratified by sex. Thus, we aimed to establish sex-specific reference intervals for hematologic and biochemical parameters in Sprague-Dawley rats according to Clinical and Laboratory Standards Institute C28-A3 and American Society for Veterinary Clinical Pathology guideline...
2017: PloS One
https://www.readbyqxmd.com/read/29248218/diagnostic-performance-of-cytology-for-assessment-of-hepatic-lipid-content-in-dairy-cattle
#16
M M Fry, B Yao, C Ríos, C Wong, S Mann, J A A McArt, D V Nydam, F A Leal Yepes, L Viesselmann, A Geick, K Goldin, A Jordan, E Behling-Kelly
The objective of our study was to characterize the diagnostic performance of cytology for assessing hepatic lipid content (HLC) in dairy cows by comparing microscopic evaluation of lipid vacuolation in touch imprint slide preparations of liver biopsies with quantitative measurement of triglyceride concentration ([TG]; mg/mg of wet weight) in paired biopsy samples. Our study also sought to compare the diagnostic performance of liver cytology, plasma nonesterified fatty acid concentration ([NEFA]), and plasma β-hydroxybutyrate concentration ([BHB]) derived from a measurement performed on whole blood, for assessing HLC...
December 13, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29244598/associations-of-patient-characteristics-disease-stage-and-biopsy-technique-with-the-diagnostic-quality-of-core-needle-renal-biopsy-specimens-from-dogs-with-suspected-kidney-disease
#17
Leandro Z Crivellenti, Rachel Cianciolo, Thomas Wittum, George E Lees, Christopher A Adin
OBJECTIVE To identify factors affecting the diagnostic quality of core needle renal biopsy specimens from dogs with suspected kidney disease. DESIGN Cross-sectional study. ANIMALS 522 client-owned dogs with suspected kidney disease for which core needle renal biopsy specimens (n = 1,089) were submitted to the International Veterinary Renal Pathology Service for evaluation and inclusion in their database. PROCEDURES Data regarding dog signalment, clinical variables, biopsy method, needle brand and gauge, biopsy results, and other variables were extracted from the database...
January 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29227138/a-comparison-of-mycotoxin-contamination-of-premium-and-grocery-brands-of-pelleted-cat-food-in-south-africa
#18
Sanil D Singh, Sooraj Baijnath, Anil A Chuturgoon
Contamination with mycotoxins is of concern to pet owners and veterinary practitioners owing to their ability to cause disease and exacerbate the pathological changes associated with other diseases. Currently, there is a lack of information regarding the mycotoxin content of common premium brand (PB) and grocery brand (GB) cat feeds. Therefore, we undertook to determine the mycobiota content of feed samples, from both categories (n = 6 each), and measured the levels of aflatoxin (AF), fumonisin (FB), ochratoxin A (OTA) and zearalenone (ZEA) by high performance liquid chromatographic analysis...
November 22, 2017: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/29224512/analytical-validation-of-cardiac-troponin-i-assays-in-horses
#19
Tanya M Rossi, Peter A Kavsak, M Grant Maxie, David L Pearl, W Glen Pyle, Peter W Physick-Sheard
Human cardiac troponin I (cTnI) assays have been used in equine medicine, often without prior analytical validation for equine use. In the absence of appropriate validation, the clinical significance of assay results is uncertain and can lead to misdiagnosis. We followed the American Society for Veterinary Clinical Pathology guidelines and investigated linearity, precision, limit of quantification (LoQ), and comparative recovery for 6 commercial cTnI assays developed for use in human medicine. Clinically acceptable linearity was observed in assays A-D, whereas assay E did not detect equine cTnI in any sample...
December 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29208216/clinical-veterinary-proteomics-techniques-and-approaches-to-decipher-the-animal-plasma-proteome
#20
REVIEW
P Ghodasara, P Sadowski, N Satake, S Kopp, P C Mills
Over the last two decades, technological advancements in the field of proteomics have advanced our understanding of the complex biological systems of living organisms. Techniques based on mass spectrometry (MS) have emerged as powerful tools to contextualise existing genomic information and to create quantitative protein profiles from plasma, tissues or cell lines of various species. Proteomic approaches have been used increasingly in veterinary science to investigate biological processes responsible for growth, reproduction and pathological events...
December 2017: Veterinary Journal
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