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https://www.readbyqxmd.com/read/29020888/clinical-haematology-and-biochemistry-profiles-of-cattle-naturally-infected-with-theileria-orientalis-ikeda-type-in-new-zealand
#1
K E Lawrence, S F Forsyth, B Vaatstra, A M J McFadden, D Pulford, K Govindaraju, W Pomroy
AIMS: To present the haematology and biochemistry profiles for cattle in New Zealand naturally infected with Theileria orientalis Ikeda type and investigate if the results differed between adult dairy cattle and calves aged <6 months. METHODS: Haematology and biochemistry results were obtained from blood samples from cattle which tested positive for T. orientalis Ikeda type by PCR, that were submitted to veterinary laboratories in New Zealand between October 2012 and November 2014...
October 11, 2017: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/28971522/half-a-century-of-equine-reproduction-research-and-application-a-veterinary-tour-de-force
#2
REVIEW
Twink W R Allen, S Wilsher
Over the past 50 years, pregnancy rates in Thoroughbred mares have risen from 70 to >90% and foaling rates from 55 to >80%. Some of the significant pharmacological treatments and diagnostic methods which have driven this marked improvement in breeding efficiency are reviewed. They include the application of artificial lighting to hasten the onset of ovulatory oestrous cyclicity in early Spring, rapid steroid hormone assays to aid in determining the stage and normality of the mare's cycle, prostaglandin analogues, synthetic progestagens and Gonadotrophin-releasing Hormone (GnRH) analogues to better control and manipulate her cycle to good effect, transrectal ultrasound scanning to monitor follicle growth, endometrial architecture and ovulation and to allow accurate, early pregnancy diagnosis thereby enabling successful ablation of one of twin conceptuses...
October 3, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28942301/the-journal-of-comparative-pathology-educational-trust-and-petplan-charitable-trust-joint-research-award-in-veterinary-pathology
#3
EDITORIAL
M J Day
No abstract text is available yet for this article.
August 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28920818/biochemistry-panel-reference-intervals-for-juvenile-goldfish-carassius-auratus
#4
Laura A Adamovicz, Macy R Trosclair, Gregory A Lewbart
Reference intervals for diagnostic tests are vitally important for clinical decision making. Despite the popularity of pet goldfish (Carassius auratus), reference intervals have not been generated for routine biochemistry panel analytes in this species. This study establishes de novo reference intervals for packed cell volume and total solids, using 47 apparently healthy immature goldfish, and for 11 common chemistry panel analytes (albumin, aspartate aminotransferase, calcium, creatine kinase, globulin, blood glucose, sodium, potassium, phosphorous, total protein, and uric acid) using 39 immature goldfish...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28875534/postmortem-dti-reveals-altered-hippocampal-connectivity-in-wild-sea-lions-diagnosed-with-chronic-toxicosis-from-algal-exposure
#5
Peter F Cook, Gregory S Berns, Kathleen Colegrove, Shawn Johnson, Frances Gulland
Hundreds of wild California sea lions (Zalophus californianus) exposed to the algal neurotoxin domoic acid are treated in veterinary rehabilitation centers each year. Common chronic effects of toxic exposure in these animals are seizures and hippocampal damage, and they have been proposed as a natural animal model for human epilepsy. Humans with medial temporal lobe epilepsy present with white matter pathology in a number of tracts including the fornix and increased structural connectivity between the hippocampus and thalamus...
September 5, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28868746/corrigendum
#6
(no author information available yet)
In Pathology International vol 62 iss 1, the authors would like to draw the reader's attention to the error: On page 28, College of Veterinary Medicine, Seoul National University, Seoul, Korea was not included as an affiliation for author, Jun Won Park. The corrected author affiliation list is: Hee Seok Lee,(1) * Jun Won Park,(1,4) * Oleg Chertov,(2) Simona Colantonio,(2) John T. Simpson,(2) Matthew J. Fivash,(3) Chong Woo Yoo,(1) Geon Kook Lee,(1) Jae Ill Zo,(1) Heung Tae Kim(1) and Hark Kyun Kim(1)(1) National Cancer Center, Goyang, Korea and (2) Protein Chemistry Laboratory Advanced Technology Program, SAIC-Frederick, Inc...
September 2017: Pathology International
https://www.readbyqxmd.com/read/28861517/the-microtubule-stabilizing-protein-clasp1-associates-with-the-theileria-annulata-schizont-surface-via-its-kinetochore-binding-domain
#7
Sandra Huber, Romina Theiler, Daniel de Quervain, Olga Wiens, Tulin Karangenc, Volker Heussler, Dirk Dobbelaere, Kerry Woods
Theileria is an apicomplexan parasite whose presence within the cytoplasm of a leukocyte induces cellular transformation and causes uncontrolled proliferation and clonal expansion of the infected cell. The intracellular schizont utilizes the host cell's own mitotic machinery to ensure its distribution to both daughter cells by associating closely with microtubules (MTs) and incorporating itself within the central spindle. We show that CLASP1, an MT-stabilizing protein that plays important roles in regulating kinetochore-MT attachment and central spindle positioning, is sequestered at the Theileria annulata schizont surface...
July 2017: MSphere
https://www.readbyqxmd.com/read/28838294/feline-leprosy-due-to-candidatus-mycobacterium-lepraefelis-further-clinical-and-molecular-characterisation-of-eight-previously-reported-cases-and-an-additional-30-cases
#8
Carolyn R O'Brien, Richard Malik, Maria Globan, George Reppas, Christina McCowan, Janet A Fyfe
OBJECTIVES: This paper, the last in a series of three on 'feline leprosy', provides a detailed description of disease referable to the previously unnamed species, Candidatus 'Mycobacterium lepraefelis', a close relative of the human pathogens Mycobacterium leprae and Mycobacterium lepromatosis. METHODS: Cases were sourced retrospectively and prospectively for this observational study, describing clinical, geographical and molecular microbiological data for cats definitively diagnosed with Candidatus 'M lepraefelis' infection...
September 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28833365/magnetic-resonance-imaging-findings-of-the-proximal-metacarpus-in-quarter-horses-used-for-cutting-retrospective-analysis-of-32-horses-2009-2012
#9
M F Barrett, P T Manchon, J Hersman, C E Kawcak
BACKGROUND: Injury to the proximal suspensory ligament is a common cause of lameness in cutting horses. Radiographic and ultrasonographic imaging of lesions responsible for lameness can provide ambiguous results. MRI provides the most comprehensive diagnostic imaging evaluation of lesions specifically affecting cutting horses. OBJECTIVES: Describe the distribution and severity of bone and soft tissue lesions present in the proximal metacarpus of Quarter Horse cutting horses and assess the impact of these lesions on return to competition...
August 18, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28830430/tick-borne-encephalitis-in-a-naturally-infected-sheep
#10
Brigitte Böhm, Benjamin Schade, Benjamin Bauer, Bernd Hoffmann, Donata Hoffmann, Ute Ziegler, Martin Beer, Christine Klaus, Herbert Weissenböck, Jens Böttcher
BACKGROUND: Tick-borne encephalitis (TBE) is the most important viral tick borne zoonosis in Europe. In Germany, about 250 human cases are registered annually, with the highest incidence reported in the last years coming from the federal states Bavaria and Baden-Wuerttemberg. In veterinary medicine, only sporadic cases in wild and domestic animals have been reported; however, a high number of wild and domestic animals have tested positive for the tick-borne encephalitis virus (TBEV) antibody...
August 22, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28822691/fatal-meningitis-in-swine-after-intrathecal-administration-of-adeno-associated-virus-expressing-syngeneic-interleukin-10
#11
Mark D Unger, Josef Pleticha, James E Collins, Anibal G Armien, Jennifer L Brazzell, Laura K Newman, Lukas F Heilmann, Jodi A Scholz, Timothy P Maus, Andreas S Beutler
Interleukin-10 (IL-10) delivered by intrathecal (i.t.) gene vectors is a candidate investigational new drug (IND) for several chronic neurological disorders such as neuropathic pain. We performed a preclinical safety study of IL-10. A syngeneic large animal model was used delivering porcine IL-10 (pIL-10) to the i.t. space in swine by adeno-associated virus serotype 8 (AAV8), a gene vector that was previously found to be nontoxic in the i.t. space. Unexpectedly, animals became ill, developing ataxia, seizures, and an inability to feed and drink, and required euthanasia...
August 1, 2017: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/28805487/state-of-the-art-nanopathological-diagnostics
#12
Luca Roncati, Giuseppe Barbolini
The nanopathological diagnostics (ND) is an ultra-specialized branch of pathological anatomy aimed to identify the nanoparticles of metallic, semimetallic, or nonmetallic elements in the inorganic particulate matter present inside pathological tissues, even on the nanometer scale. ND exploits an environmental scanning electron microscope, connected to an X-ray microprobe mounted on an energy-dispersive spectrometer. The searching of nanoparticles can be performed on paraffin-embedded material, omitting emissions of black overlay and plating procedures...
September 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28804855/human-heart-failure-with-preserved-ejection-versus-feline-cardiomyopathy-what-can-we-learn-from-both-veterinary-and-human-medicine
#13
REVIEW
Valentine Prat, Bertrand Rozec, Chantal Gauthier, Benjamin Lauzier
Cardiovascular affections are a growing health burden in human populations. Recent advances in cardiology have improved treatments and outcomes for myocardial infarction and arrhythmias, but other conditions still remain poorly understood. To date, the classical approach to study cardiovascular diseases involves rodent models, despite their strong differences with human cardiac physiology. In this context, this review will focus on the common traits between human and feline cardiac diseases, namely heart failure with preserved ejection fraction and feline cardiomyopathies, respectively...
August 14, 2017: Heart Failure Reviews
https://www.readbyqxmd.com/read/28802138/inhibition-of-bioenergetic-metabolism-by-the-combination-of-metformin-and-2-deoxyglucose-highly-decreases-viability-of-feline-mammary-carcinoma-cells
#14
María Florencia Arbe, Chiara Fondello, Lucrecia Agnetti, Gabriel Martín Álvarez, Matías Nicolás Tellado, Gerardo Claudio Glikin, Liliana María Elena Finocchiaro, Marcela Solange Villaverde
Feline mammary carcinoma (FMC) is a highly aggressive pathology that has been proposed as an interesting model of breast cancer disease, especially for the hormone refractory subgroup. Recently, cancer cell metabolism has been described as a hallmark of cancer cells. Here, we investigate the effects and mechanism of metabolic modulation by metformin (MET, anti-diabetic drug), 2-deoxyglucose (2DG, hexokinase inhibitor) or a combination of both drugs, MET/2DG on two established FMC cells lines: AlRB (HER2 (3+) and Ki67<5%) and AlRATN (HER2 (-) and Ki67>15%)...
August 3, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28782436/charcot-leyden-crystals-do-they-exist-in-veterinary-species-a-case-report-and-literature-review
#15
Eunju Choi, Andrew D Miller, Elizabeth Devenish, Makoto Asakawa, Marina McConkey, Jeanine Peters-Kennedy
The Charcot-Leyden crystal (CLC) is a major human eosinophil protein that readily crystallizes; these crystals are common in eosinophilic diseases. Although anecdotal existence of these crystals is known in veterinary pathology, definitive reports do not exist, to our knowledge. We identified eosinophilic crystals in a laryngeal myxosarcoma from a 2-y-old, spayed female, Labrador Retriever dog that were tentatively interpreted as CLCs. However, Ziehl-Neelsen acid-fast stain was negative, arguing against CLCs...
August 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28781334/the-first-report-of-the-ante-mortem-diagnosis-of-ollulanus-tricuspis-infection-in-two-dogs
#16
Daiki Kato, Mariko Oishi, Koichi Ohno, Ko Nakashima, Atsuhito Wada, Shin-Ichiro Fukumoto, Tatsushi Morita, Soichi Imai, Masaya Tsuboi, James K Chambers, Kazuyuki Uchida, Hajime Tsujimoto
NOTE Internal Medicine The first report of the ante-mortem diagnosis of Ollulanus tricuspis infection in two dogs Daiki KATO(1)), Mariko OISHI(1)), Koichi OHNO(1)*), Ko NAKASHIMA(1)), Atsuhito WADA(1)), Tatsushi MORITA(2)), Soichi IMAI(2)), Masaya TSUBOI(3)), James K. CHAMBERS(3)), Kazuyuki UCHIDA(3)) and Hajime TSUJIMOTO(1))(1))Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan (2))Division of Veterinary Infectious Disease, Department of Veterinary Pathobiology, Nippon Veterinary and Life Science University, 1-7-1 Kyonanchyo Musashino, Tokyo 180-8602, Japan (3))Department of Veterinary Pathology, Graduate School of Agricultural Should have been NOTE Internal Medicine The first report of the ante-mortem diagnosis of Ollulanus tricuspis infection in two dogs Daiki KATO(1)), Mariko OISHI(1)), Koichi OHNO(1)*), Ko NAKASHIMA(1)), Atsuhito WADA(1)), Shin-ichiro FUKUMOTO(2)), Tatsushi MORITA(3)), Soichi IMAI(3)), Masaya TSUBOI(4)), James K...
2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/28763127/european-veterinary-renal-pathology-service-a-survey-over-a-7-year-period-2008-2015
#17
L Aresu, V Martini, S L Benali, C Brovida, R E Cianciolo, R Dalla Riva, D Trez, J J Van Der Lugt, A Van Dongen, E Zini
BACKGROUND: The European Veterinary Renal Pathology Service (EVRPS) is the first Web-based registry for canine renal biopsy specimens in Europe. HYPOTHESIS/OBJECTIVES: The aim was to verify whether differences exist between the clinical and laboratory presentation of dogs with nephropathy according to renal pathological findings, as defined by light and electron microscopy of renal biopsy specimens submitted to EVRPS. ANIMALS: Renal biopsy specimens of dogs were collected from the archive of the service (n = 254)...
September 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28749750/microbial-offense-vs-host-defense-who-controls-the-tb-granuloma
#18
Amanda J Martinot
The granuloma is the hallmark of tuberculosis and simultaneously signifies acquisition of an infection and induction of a host immune response. But who benefits more from the development of the granuloma, the host or the pathogen? Is microbe or man dictating disease course and progression? Mycobacterial diseases affect humans and animals alike, and the concepts presented in this review reflect host-pathogen interactions that influence not only mycobacterial granulomas in humans and animals but also other infectious granulomatous diseases that are encountered in veterinary medicine...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28749265/emergency-anesthesia-and-exploratory-laparotomy-in-a-compromised-pacific-white-sided-dolphin-lagenorhynchus-obliquidens
#19
Justin F Rosenberg, Martin Haulena, James E Bailey, Dean A Hendrickson, Marina Ivančić, Stephen A Raverty
Anesthesia and surgery in cetaceans have inherent risks and have rarely been utilized as viable treatment options. This report represents the first known multidisciplinary team approach to emergency laparotomy in a compromised, 22-yr-old, female Pacific white-sided dolphin ( Lagenorhynchus obliquidens ). The inciting clinical signs and ancillary diagnostics were consistent with a mechanical ileus. Although no torsion or obstruction was apparent during surgery, severe enteritis and peritonitis were noted. Postoperatively, the animal was maintained on aggressive medical management with continuous supportive care until succumbing 3 days later with clinical pathology indicative of terminal sepsis and profound inflammation...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28747984/annual-tendency-of-research-papers-used-icr-mice-as-experimental-animals-in-biomedical-research-fields
#20
Ji Eun Kim, Jung Hoon Nam, Joon Young Cho, Kil Soo Kim, Dae Youn Hwang
Institute of Cancer Research (ICR) mice have been widely used in various research fields including toxicology, oncology, pharmacology, and pharmaceutical product safety testing for decades. However, annual tendency of research papers involving ICR mice in various biomedical fields has not been previously analyzed. In this study, we examined the numbers of papers that used ICR mice as experimental animals in the social science, natural science, engineering, medicine-pharmacy, marine agriculture-fishery, and art-kinesiology fields by analyzing big data...
June 2017: Laboratory Animal Research
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