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Veterinary pathology

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https://www.readbyqxmd.com/read/29208216/clinical-veterinary-proteomics-techniques-and-approaches-to-decipher-the-animal-plasma-proteome
#1
REVIEW
P Ghodasara, P Sadowski, N Satake, S Kopp, P C Mills
Over the last two decades, technological advancements in the field of proteomics have advanced our understanding of the complex biological systems of living organisms. Techniques based on mass spectrometry (MS) have emerged as powerful tools to contextualise existing genomic information and to create quantitative protein profiles from plasma, tissues or cell lines of various species. Proteomic approaches have been used increasingly in veterinary science to investigate biological processes responsible for growth, reproduction and pathological events...
December 2017: Veterinary Journal
https://www.readbyqxmd.com/read/29205375/comparison-of-direct-in-house-cerebrospinal-fluid-cytology-with-commercial-pathology-results-in-dogs
#2
P L Newton, D R Fry, M P Best
OBJECTIVES: To investigate the correspondence between in-house direct cytological assessment of cerebrospinal fluid and results from a commercial veterinary pathology laboratory. METHODS: Prospective inclusion of samples from dogs that were presented for investigation of suspected neurological disease and had cerebrospinal fluid samples submitted to a commercial pathology laboratory for analysis. A board-certified veterinary pathologist assessed all cerebrospinal fluid samples, and a line smear was assessed in-house by two observers...
December 2017: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/29188759/identifying-free-text-features-to-improve-automated-classification-of-structured-histopathology-reports-for-feline-small-intestinal-disease
#3
Abdullah Awaysheh, Jeffrey Wilcke, François Elvinger, Loren Rees, Weiguo Fan, Kurt Zimmerman
The histologic evaluation of gastrointestinal (GI) biopsies is the standard for diagnosis of a variety of GI diseases (e.g., inflammatory bowel disease [IBD] and alimentary lymphoma [ALA]). The World Small Animal Veterinary Association (WSAVA) Gastrointestinal International Standardization Group proposed a reporting standard for GI biopsies consisting of a defined set of microscopic features. We compared the machine classification accuracy of free-text microscopic findings with those represented in the WSAVA format with a diagnosis of IBD and ALA...
November 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29177055/population-characteristics-of-golden-retriever-lifetime-study-enrollees
#4
Melissa Simpson, Erin Searfoss, Sharon Albright, Diane E Brown, Barbara Wolfe, Nancy K Clark, Susan E McCann, David Haworth, Mike Guy, Rod Page
Background: Studying cancer and other diseases poses a problem due to their protracted and multifactorial nature. Prospective studies are useful to investigate chronic disease processes since collection of lifestyle information, exposure data and co-incident health issues are collected before the condition manifests. The Golden Retriever Lifetime Study is one of the first prospective studies following privately-owned dogs throughout life to investigate the incidence and risk factors for disease outcomes, especially cancer...
2017: Canine Genetics and Epidemiology
https://www.readbyqxmd.com/read/29159852/orbital-invasive-squamous-cell-carcinoma-with-adnexal-involvement-clinically-mimicking-feline-restrictive-orbital-myofibroblastic-sarcoma-19-cases-1990-2016
#5
Kathryn A Diehl, Silvia G Pryor, Leandro Bc Teixeira
OBJECTIVE: To describe the clinical presentations of patients diagnosed with ocular adnexal or orbital squamous cell carcinoma (SCC), which possess features similar to feline restrictive orbital myofibroblastic sarcoma (FROMS). PROCEDURES: A retrospective review of adnexal and/or orbital SCC was performed. Cases were collected from the University of Georgia College of Veterinary Medicine and the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) (1990-2016)...
November 21, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29143657/clinical-benefits-of-incorporating-doxycycline-into-a-canine-heartworm-treatment-protocol
#6
C Thomas Nelson, Elizabeth S Myrick, Thomas A Nelson
BACKGROUND: The objective of heartworm treatment is to improve the clinical condition of the patient and to eliminate pre-cardiac, juvenile, and adult worm stages with minimal complications. Pulmonary thromboembolisms are an inevitable consequence of worm death and can result in severe pulmonary reactions and even death of the patient. To minimize these reactions, various treatment protocols involving melarsomine, the only adulticidal drug approved by the US Food and Drug Administrations (FDA), in conjunction with macrocyclic lactone heartworm preventives and glucocorticosteroids have been advocated...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29138745/spontaneous-nervous-system-concussion-in-dogs-a-description-of-two-cases-and-a-review-of-terminology-in-veterinary-medicine
#7
Angelo Pasquale Giannuzzi, Antonio De Simone, Mario Ricciardi
In human medicine, central nervous system (CNS) concussion is defined as a transient neurological dysfunction following a traumatic event, without evidence of structural abnormalities of the affected region on advanced diagnostic imaging. Depending on the anatomical region involved, three forms of concussive syndromes are described: brain concussion, spinal concussion and cerebellar concussion. Although major textbooks of veterinary neurology admit the existence of canine brain concussion, spontaneous cases of this pathological condition have not been reported in small animals so far...
2017: Open Veterinary Journal
https://www.readbyqxmd.com/read/29126143/understanding-how-dogs-age-longitudinal-analysis-of-markers-of-inflammation-immune-function-and-oxidative-stress
#8
Janet E Alexander, Alison Colyer, Richard M Haydock, Michael G Hayek, JeanSoon Park, Rafael de Cabo
As in human populations, advances in nutrition and veterinary care have led to an increase in the lifespan of companion animals. Detrimental physiological changes occurring later in life must be understood before interventions can be made to slow or reduce them. One important aspect of human aging is upregulation of the inflammatory response and increase in oxidative damage resulting in pathologies linked to chronic inflammation. To determine whether similar processes occur in the aging dog, changes in markers of inflammation and oxidative stress were investigated in 80 Labrador retrievers from adulthood to the end of life...
November 6, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29115950/the-prevalence-of-ocular-diseases-in-polish-arabian-horses
#9
Katarzyna Paschalis-Trela, Anna Cywińska, Jan Trela, Michał Czopowicz, Jerzy Kita, Lucjan Witkowski
BACKGROUND: Equine ocular diseases pose a medical challenge due to long-lasting and cost-consuming therapies as well as economic issues associated with potential decrease in value of affected horses. The scale of the problem is significant but difficult to precisely define because epidemiological data is limited and lacks consistency in presentation. To date, no retrospective studies specifically investigating Arabian horses have been published. RESULTS: The aim of this cross-sectional study was to investigate the prevalence of ocular lesions and define the ocular diseases present in Arabian horses from breeding farms in Poland...
November 7, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29104410/human-aided-movement-of-viral-disease-and-the-archaeology-of-avian-osteopetrosis
#10
B Tyr Fothergill
The term avian osteopetrosis is used to describe alterations to the skeletal elements of several species of domestic bird, most typically the chicken, Gallus gallus domesticus (L. 1758). Such lesions are routinely identified in animal bones from archaeological sites due to their distinctive appearance, which is characterised by proliferative diaphyseal thickening. These lesions are relatively uncomplicated for specialists to differentially diagnose and are caused by a range of avian leucosis viruses in a series of subgroups...
September 2017: International Journal of Osteoarchaeology
https://www.readbyqxmd.com/read/29020888/clinical-haematology-and-biochemistry-profiles-of-cattle-naturally-infected-with-theileria-orientalis-ikeda-type-in-new-zealand
#11
K E Lawrence, S F Forsyth, B L Vaatstra, Amj McFadden, D J Pulford, K Govindaraju, W E Pomroy
AIMS: To present the haematology and biochemistry profiles for cattle in New Zealand naturally infected with Theileria orientalis Ikeda type and investigate if the results differed between adult dairy cattle and calves aged <6 months. METHODS: Haematology and biochemistry results were obtained from blood samples from cattle which tested positive for T. orientalis Ikeda type by PCR, that were submitted to veterinary laboratories in New Zealand between October 2012 and November 2014...
January 2018: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/28971522/half-a-century-of-equine-reproduction-research-and-application-a-veterinary-tour-de-force
#12
REVIEW
Twink W R Allen, S Wilsher
Over the past 50 years, pregnancy rates in Thoroughbred mares have risen from 70 to >90% and foaling rates from 55 to >80%. Some of the significant pharmacological treatments and diagnostic methods which have driven this marked improvement in breeding efficiency are reviewed. They include the application of artificial lighting to hasten the onset of ovulatory oestrous cyclicity in early Spring, rapid steroid hormone assays to aid in determining the stage and normality of the mare's cycle, prostaglandin analogues, synthetic progestagens and Gonadotrophin-releasing Hormone (GnRH) analogues to better control and manipulate her cycle to good effect, transrectal ultrasound scanning to monitor follicle growth, endometrial architecture and ovulation and to allow accurate, early pregnancy diagnosis thereby enabling successful ablation of one of twin conceptuses...
October 3, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28942301/the-journal-of-comparative-pathology-educational-trust-and-petplan-charitable-trust-joint-research-award-in-veterinary-pathology
#13
EDITORIAL
M J Day
No abstract text is available yet for this article.
August 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28920818/biochemistry-panel-reference-intervals-for-juvenile-goldfish-carassius-auratus
#14
Laura A Adamovicz, Macy R Trosclair, Gregory A Lewbart
Reference intervals for diagnostic tests are vitally important for clinical decision making. Despite the popularity of pet goldfish (Carassius auratus), reference intervals have not been generated for routine biochemistry panel analytes in this species. This study establishes de novo reference intervals for packed cell volume and total solids, using 47 apparently healthy immature goldfish, and for 11 common chemistry panel analytes (albumin, aspartate aminotransferase, calcium, creatine kinase, globulin, blood glucose, sodium, potassium, phosphorous, total protein, and uric acid) using 39 immature goldfish...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28875534/postmortem-dti-reveals-altered-hippocampal-connectivity-in-wild-sea-lions-diagnosed-with-chronic-toxicosis-from-algal-exposure
#15
Peter F Cook, Gregory S Berns, Kathleen Colegrove, Shawn Johnson, Frances Gulland
Hundreds of wild California sea lions (Zalophus californianus) exposed to the algal neurotoxin domoic acid are treated in veterinary rehabilitation centers each year. Common chronic effects of toxic exposure in these animals are seizures and hippocampal damage, and they have been proposed as a natural animal model for human epilepsy. Humans with medial temporal lobe epilepsy present with white matter pathology in a number of tracts including the fornix and increased structural connectivity between the hippocampus and thalamus...
September 5, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28868746/corrigendum
#16
(no author information available yet)
In Pathology International vol 62 iss 1, the authors would like to draw the reader's attention to the error: On page 28, College of Veterinary Medicine, Seoul National University, Seoul, Korea was not included as an affiliation for author, Jun Won Park. The corrected author affiliation list is: Hee Seok Lee,(1) * Jun Won Park,(1,4) * Oleg Chertov,(2) Simona Colantonio,(2) John T. Simpson,(2) Matthew J. Fivash,(3) Chong Woo Yoo,(1) Geon Kook Lee,(1) Jae Ill Zo,(1) Heung Tae Kim(1) and Hark Kyun Kim(1)(1) National Cancer Center, Goyang, Korea and (2) Protein Chemistry Laboratory Advanced Technology Program, SAIC-Frederick, Inc...
September 2017: Pathology International
https://www.readbyqxmd.com/read/28861517/the-microtubule-stabilizing-protein-clasp1-associates-with-the-theileria-annulata-schizont-surface-via-its-kinetochore-binding-domain
#17
Sandra Huber, Romina Theiler, Daniel de Quervain, Olga Wiens, Tulin Karangenc, Volker Heussler, Dirk Dobbelaere, Kerry Woods
Theileria is an apicomplexan parasite whose presence within the cytoplasm of a leukocyte induces cellular transformation and causes uncontrolled proliferation and clonal expansion of the infected cell. The intracellular schizont utilizes the host cell's own mitotic machinery to ensure its distribution to both daughter cells by associating closely with microtubules (MTs) and incorporating itself within the central spindle. We show that CLASP1, an MT-stabilizing protein that plays important roles in regulating kinetochore-MT attachment and central spindle positioning, is sequestered at the Theileria annulata schizont surface...
July 2017: MSphere
https://www.readbyqxmd.com/read/28838294/feline-leprosy-due-to-candidatus-mycobacterium-lepraefelis-further-clinical-and-molecular-characterisation-of-eight-previously-reported-cases-and-an-additional-30-cases
#18
Carolyn R O'Brien, Richard Malik, Maria Globan, George Reppas, Christina McCowan, Janet A Fyfe
OBJECTIVES: This paper, the last in a series of three on 'feline leprosy', provides a detailed description of disease referable to the previously unnamed species, Candidatus 'Mycobacterium lepraefelis', a close relative of the human pathogens Mycobacterium leprae and Mycobacterium lepromatosis. METHODS: Cases were sourced retrospectively and prospectively for this observational study, describing clinical, geographical and molecular microbiological data for cats definitively diagnosed with Candidatus 'M lepraefelis' infection...
September 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28833365/magnetic-resonance-imaging-findings-of-the-proximal-metacarpus-in-quarter-horses-used-for-cutting-retrospective-analysis-of-32-horses-2009-2012
#19
M F Barrett, P T Manchon, J Hersman, C E Kawcak
BACKGROUND: Injury to the proximal suspensory ligament is a common cause of lameness in cutting horses. Radiographic and ultrasonographic imaging of lesions responsible for lameness can provide ambiguous results. MRI provides the most comprehensive diagnostic imaging evaluation of lesions specifically affecting cutting horses. OBJECTIVES: Describe the distribution and severity of bone and soft tissue lesions present in the proximal metacarpus of Quarter Horse cutting horses and assess the impact of these lesions on return to competition...
August 18, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28830430/tick-borne-encephalitis-in-a-naturally-infected-sheep
#20
Brigitte Böhm, Benjamin Schade, Benjamin Bauer, Bernd Hoffmann, Donata Hoffmann, Ute Ziegler, Martin Beer, Christine Klaus, Herbert Weissenböck, Jens Böttcher
BACKGROUND: Tick-borne encephalitis (TBE) is the most important viral tick borne zoonosis in Europe. In Germany, about 250 human cases are registered annually, with the highest incidence reported in the last years coming from the federal states Bavaria and Baden-Wuerttemberg. In veterinary medicine, only sporadic cases in wild and domestic animals have been reported; however, a high number of wild and domestic animals have tested positive for the tick-borne encephalitis virus (TBEV) antibody...
August 22, 2017: BMC Veterinary Research
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