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Pulmonary hypertension mitral replacement

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https://www.readbyqxmd.com/read/28105998/simultaneous-transfemoral-aortic-and-transseptal-mitral-valve-replacement-utilising-sapien-3-valves-in-native-aortic-and-mitral-valves
#1
Mohammad Bashir, Gardar Sigurdsson, Phillip A Horwitz, Firas Zahr
AIMS: Concomitant severe calcific aortic and mitral stenosis is a relatively uncommon but very challenging valvular heart disease to manage. We sought to evaluate the feasibility of a fully percutaneous approach to replace both stenotic native mitral and aortic valves using SAPIEN 3 valves. METHODS AND RESULTS: An 87-year-old woman with chronic kidney disease stage 3, pul-monary hypertension, chronic obstructive pulmonary disease, a permanent pacemaker, and atrial fibrillation was referred with Class III heart failure symptoms...
January 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28100277/stress-echo-2020-the-international-stress-echo-study-in-ischemic-and-non-ischemic-heart-disease
#2
Eugenio Picano, Quirino Ciampi, Rodolfo Citro, Antonello D'Andrea, Maria Chiara Scali, Lauro Cortigiani, Iacopo Olivotto, Fabio Mori, Maurizio Galderisi, Marco Fabio Costantino, Lorenza Pratali, Giovanni Di Salvo, Eduardo Bossone, Francesco Ferrara, Luna Gargani, Fausto Rigo, Nicola Gaibazzi, Giuseppe Limongelli, Giuseppe Pacileo, Maria Grazia Andreassi, Bruno Pinamonti, Laura Massa, Marco A R Torres, Marcelo H Miglioranza, Clarissa Borguezan Daros, José Luis de Castro E Silva Pretto, Branko Beleslin, Ana Djordjevic-Dikic, Albert Varga, Attila Palinkas, Gergely Agoston, Dario Gregori, Paolo Trambaiolo, Sergio Severino, Ayana Arystan, Marco Paterni, Clara Carpeggiani, Paolo Colonna
BACKGROUND: Stress echocardiography (SE) has an established role in evidence-based guidelines, but recently its breadth and variety of applications have extended well beyond coronary artery disease (CAD). We lack a prospective research study of SE applications, in and beyond CAD, also considering a variety of signs in addition to regional wall motion abnormalities. METHODS: In a prospective, multicenter, international, observational study design, > 100 certified high-volume SE labs (initially from Italy, Brazil, Hungary, and Serbia) will be networked with an organized system of clinical, laboratory and imaging data collection at the time of physical or pharmacological SE, with structured follow-up information...
January 18, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28079786/fatal-postoperative-systemic-pulmonary-hypertension-in-benfluorex-induced-valvular-heart-disease-surgery-a-case-report
#3
Christophe Baufreton, Patrick Bruneval, Marie-Christine Rousselet, Pierre-Vladimir Ennezat, Olivier Fouquet, Raphael Giraud, Carlo Banfi
RATIONALE: Drug-induced valvular heart disease (DI-VHD) remains an under-recognized entity. PATIENT CONCERNS: This report describes a heart valve replacement which was complicated by intractable systemic pulmonary arterial hypertension in a 61-year-old female with severe restrictive mitral and aortic disease. The diagnosis of valvular disease was preceded by a history of unexplained respiratory distress. The patient had been exposed to benfluorex for 6.5 years. DIAGNOSES: The diagnostic procedure documented specific drug-induced valvular fibrosis...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28050459/cardiovascular-abnormalities-in-egyptian-children-with-mucopolysaccharidoses
#4
Laila Selim, Nehal Abdelhamid, Emad Salama, Amera Elbadawy, Iman Gamaleldin, Mohamed Abdelmoneim, Abeer Selim
INTRODUCTION: The Mucopolysaccharidoses (MPS) are rare inherited metabolic disorders. They are characterized by the progressive systemic deposition of Glycosaminoglycans (GAGs). GAGs accumulate in the myocardium and the cardiac valves. Enzyme Replacement Therapy (ERT) is available for MPS I, II, and VI. However, ERT does not appear to improve cardiac valve disease in patients with valve disease present at the start of ERT. AIM: To evaluate the cardiac involvement in Egyptian children with MPS...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27989082/impact-of-prosthesis-patient-mismatch-after-mitral-valve-replacement
#5
Calogera Pisano, Carmela Rita Balistreri, Oreste Fabio Triolo, Rosalba Franchino, Alberto Allegra, Veronica Capuccio, Vincenzo Argano, Giovanni Ruvolo
BACKGROUND: The study aim was to determine the impact of prosthesis-patient mismatch (PPM) on early and late clinical outcomes, left atrial and ventricular remodeling, late tricuspid valve regurgitation and pulmonary hypertension (PH) in patients after mitral valve replacement (MVR). METHODS: A total of 46 patients (mean age 66 ± 9.3 years) with mitral valve diseases and undergoing isolated MVR was enrolled in the study. The mitral valve effective orifice area (EOA) was determined using the continuity equation and indexed for the patient's body surface area (EOAi)...
January 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/27636399/which-type-of-valve-should-we-use-in-tricuspid-position-long-term-comparison-between-mechanical-and-biological-valves
#6
Ana Redondo Palacios, José López Menéndez, Javier Miguelena Hycka, Miren Martín García, Laura Varela Barca, Andrea Ferreiro Marzal, Rafael Muñoz Pérez, Enrique Oliva De Anquín, Ignacio García Andrade, Tomasa Centella Hernández, Daniel Celemín Canorea, Jorge Rodríguez-Roda Stuart
BACKGROUND: Nowadays, Tricuspid valve replacement (TVR) is much less common than aortic or mitral valve replacement, since repair is almost always preferable. Prosthetic tricuspid valves are associated with high mortality and morbidity, mostly due to thrombotic or hemorrhagic events. Nevertheless, there is lack of evidence of which is the optimal type of valve (biological versus mechanical) in tricuspid position. METHODS: We analysed all the patients who underwent TVR in our Institution, from 2005 to 2015...
September 16, 2016: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27625364/eclipsed-mitral-regurgitation-an-unusual-cause-of-acute-heart-failure
#7
O Milleron, C Bouleti, S Mazouz, E Brochet, F Rouzet, P Nataf, W Ghodbane, D Messika-Zeitoun, M P Dilly, S Cattan, A Vahanian, B Iung, G Jondeau
AIMS: So far, a total of five patients with eclipsed mitral regurgitation (MR) have been reported in the literature by three different teams. The aim of this article was to detail clinical and echocardiographic characteristics, and outcome of patients presenting eclipsed MR. METHODS AND RESULTS: We defined eclipsed MR as spontaneous appearance, at rest, from 1 min to the next of an acute restriction in the motion of mitral leaflets preventing coaptation and leading to massive MR in patients with normal left ventricular end-diastolic diameter, left ventricular ejection fraction >45%, and baseline MR ≤2...
September 13, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/27456367/late-outcomes-in-children-with-shone-s-complex-a-single-centre-20-year-experience
#8
George T Nicholson, Michael S Kelleman, Caridad M De la Uz, Ricardo H Pignatelli, Nancy A Ayres, Christopher J Petit
OBJECTIVE: Shone's syndrome is a complex consisting of mitral valve stenosis in addition to left ventricle outflow obstruction. There are a few studies evaluating the long-term outcomes in this population. We sought to determine the long-term outcomes in our paediatric population with Shone's syndrome and the factors associated with left heart growth. METHODS: All patients diagnosed with Shone's syndrome with biventricular circulation treated between 1978 and 2010 were reviewed...
July 26, 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/27378789/do-we-have-to-operate-on-moderate-functional-mitral-regurgitation-during-aortic-valve-replacement-for-aortic-stenosis
#9
Adam R Kowalówka, Magdalena Onyszczuk, Wojciech Wańha, Marek A Deja
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was 'Do we have to operate on moderate functional mitral regurgitation (FMR) during aortic valve replacement (AVR) for aortic stenosis (AS)?' Altogether 325 papers were found using the reported search, of which 9 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated...
November 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27372429/initial-results-and-long-term-follow-up-of-percutaneous-mitral-valvuloplasty-in-patients-with-pulmonary-hypertension
#10
Ricardo A Sarmiento, Rodrigo Blanco, Gerardo Gigena, Jorge Lax, Alejandro Garcia Escudero, Federico Blanco, Jorge Szarfer, Raul Solerno, Carlos D Tajer, Juan A Gagliardi
BACKGROUND: Percutaneous balloon mitral valvuloplasty (PMV) is an attractive therapeutic approach in patients with mitral stenosis. The aim of this study was to assess the immediate and long-term clinical, echocardiographic and haemodynamic outcomes of PMV in patients with severe pulmonary hypertension (PAH). METHODS: Percutaneous balloon mitral valvuloplasty was performed in 157 consecutive patients; 60 patients (38.2%) had significant PAH defined as baseline pulmonary artery mean pressure (PAMP) ≥ 30mm Hg (Group 1) and 97 patients (61...
January 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27342208/transcatheter-simultaneous-double-transapical-access-for-paravalvular-mitral-leak-closure-using-the-occlutech-pld
#11
Vincenzo Pestrichella, Antonio Pignatelli, Rossella Alemanni, Rosamaria Montesanti, Maurizio Braccio, Francesco Greco, Pierpaolo D'Ambruoso, Cataldo Davide Memmola, Mauro Cassese, Gaetano Contegiacomo, Rodrigo Bagur
A 67-year-old patient with rheumatic heart valve disease had undergone two cardiac surgeries at the age of 30 years, then re-do with mitral valve replacement at 50 years. She presented with congestive heart failure and hemolytic anemia. Doppler echocardiography showed moderate-severe mitral regurgitation due to paravalvular mitral valve leak (PVML) and severe pulmonary hypertension. Transesophageal echocardiography demonstrated severe PVML secondary to a large 20 mm-long PVML defect. Due to comorbidities, the heart team deemed a third reoperation at very high surgical risk; therefore, the patient was considered most suitable for a transcatheter approach to PVML closure...
July 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27306448/factor-v-and-viii-deficiency-treated-with-therapeutic-plasma-exchange-prior-to-redo-mitral-valve-replacement
#12
Laura Brown, Lowell Tilzer, Fred Plapp
A 33-year-old male was admitted to the hospital for a repeat mitral valve replacement. The original surgery, performed in India in 2008 due to rheumatic heart disease, required massive amounts of plasma replacement during and after the surgery. The patient was admitted to our hospital with extremely low Factor V and Factor VIII activities due to a rare combined Factor V and Factor VIII deficiency. His clinical condition on admission was grave due to severe pulmonary hypertension. It was decided to replace the patient's Factor V using therapeutic plasma exchange (TPE) with fresh frozen plasma (FFP) just prior to surgery, and his Factor VIII with Factor VIII concentrate...
June 16, 2016: Journal of Clinical Apheresis
https://www.readbyqxmd.com/read/27174553/male-female-differences-and-survival-in-patients-undergoing-isolated-mitral-valve-surgery-a-nationwide-cohort-study-in-the-netherlands
#13
Mostafa M Mokhles, Sabrina Siregar, Michel I M Versteegh, Luc Noyez, Bart van Putte, Alexander B A Vonk, Jolien W Roos-Hesselink, Ad J J C Bogers, Johanna J M Takkenberg
OBJECTIVES: The objective of this study was to compare male-female differences with respect to baseline characteristics and short-term outcome in a contemporary nationwide cohort of patients who underwent isolated mitral valve (MV) surgery. METHODS: All patients [N = 3411; 58% males (N = 1977)] who underwent isolated MV surgery (replacement: N = 1048, 31%; reconstruction: N = 2364, 69%) in the Netherlands between January 2007 and December 2011 were included in this study...
September 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/27136700/the-role-of-cardiac-magnetic-resonance-to-assess-the-cardiac-involvement-in-gaucher-type-1-patients-morphological-and-functional-evaluations
#14
Alberto Roghi, Erika Poggiali, Elena Cassinerio, Patrizia Pedrotti, Marianna Giuditta, Angela Milazzo, Giuseppina Quattrocchi, Maria Domenica Cappellini
BACKGROUND: Type 1 Gaucher disease (GD1) is the most common lysosomal disorder, characterized by the accumulation of beta-glucocerebroside into the macrophages of several organs. Cardiac involvement is rare and referred to as restrictive cardiomyopathy, pulmonary hypertension, and calcifications of the valves and the aortic arch. AIM: To assess the cardiovascular status by cardiac magnetic resonance, including evaluation of tissue characterization, in GD1 patients...
June 30, 2016: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/27073420/pathophysiology-of-valvular-heart-disease
#15
Y I Zeng, Rongrong Sun, Xianchi Li, Min Liu, Shuang Chen, Peiying Zhang
Valvular heart disease (VHD) is caused by either damage or defect in one of the four heart valves, aortic, mitral, tricuspid or pulmonary. Defects in these valves can be congenital or acquired. Age, gender, tobacco use, hypercholesterolemia, hypertension, and type II diabetes contribute to the risk of disease. VHD is an escalating health issue with a prevalence of 2.5% in the United States alone. Considering the likely increase of the aging population worldwide, the incidence of acquired VHD is expected to increase...
April 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27045044/the-impact-of-concomitant-pulmonary-hypertension-on-early-and-late-outcomes-following-surgery-for-mitral-stenosis
#16
Bo Yang, Christina DeBenedictus, Tessa Watt, Sean Farley, Alona Salita, Whitney Hornsby, Xiaoting Wu, Morley Herbert, Donald Likosky, Steven F Bolling
OBJECTIVES: To provide initial evidence on the management of mitral stenosis and pulmonary hypertension (PH) based on short-term and long-term outcomes following mitral valve surgery. METHODS: Consecutive patients with mitral stenosis (n = 317) who had undergone mitral valve surgery between 1992 and 2014 with recorded pulmonary artery pressure (PAP) data were reviewed. PH severity, based on systolic PAP, was categorized as mild (35 to 44 mm Hg), moderate (45 to 59 mm Hg), or severe (>60 mm Hg)...
August 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/26988837/the-valvafric-study-a-registry-of-rheumatic-heart-disease-in-western-and-central-africa
#17
Samuel Kingué, Serigne Abdou Ba, Dhadi Balde, Mamadou Bocary Diarra, Jean-Baptiste Anzouan-Kacou, Benedict Anisubia, Jean-Marie Damorou, Pierre Ndobo, Alain Menanga, Abdoul Kane, Maurice Kakou-Guikahué, Monique Kenfack, Bernard Metogo, David Chelo, Euloge Yangnigni, Cabral Tantchou, Edmond Bertrand, Jean-Jacques Monsuez
BACKGROUND: There are few African data available on rheumatic heart disease (RHD). AIM: To provide data on the clinical characteristics and treatment of patients with RHD hospitalized in sub-Saharan Africa. METHODS: The VALVAFRIC study is a multicentre hospital-based retrospective registry of patients with RHD hospitalized in African cardiology departments from 2004 to 2008. RESULTS: Among 3441 patients with at least one mild RHD lesion seen on echocardiography in 5 years in 12 cardiology departments from seven countries, 1385 had severe lesions (502 men; 803 women; mean age 29...
May 2016: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/26877419/p-115-case-report-of-severe-heart-disease-in-a-hypertensive-and-diabetic-woman-17-years-after-chest-radiation-exposure-for-breast-cancer
#18
N Ali-Tatar Chentir, M Korabi, M T Chentir
OBJECTIFS: Irradiation of the heart in patients with breast cancer increases the risk of the so-called "radiation-induced heart disease" (RIHD). Among risk factors of RIHD, overweight, hypertension and diabetes mellitus take a major place. To describe a clinical case of an obese hypertensive diabetes mellitus woman with breast cancer since the begining of her radiotherapy until heart failure on the basis of the report from the European Association of Cardiovascular Imaging consensus for evaluation of cardiovascular complications of radiotherapy in adults...
December 2015: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/26876065/incidence-of-prosthesis-patient-mismatch-in-patients-receiving-mitral-biocor%C3%A2-porcine-prosthetic-valves
#19
Raul A Borracci, Miguel Rubio, Maria L Sestito, Carlos A Ingino, Carlos Barrero, Carlos A Rapallo
BACKGROUND: The aim was to assess the incidence of prosthesis-patient mismatch (PPM) after mitral valve replacement (MVR) in patients receiving Biocor® porcine or mechanical valves, and to evaluate the effect of PPM on long-term survival. METHODS: All patients undergoing MVR between 2009 and 2013 received either mechanical or bioprosthetic valves (Biocor® porcine). PPM was defined as severe when the indexed effective ori-fice area was < 0.9 cm2/m2, moderate between 0...
2016: Cardiology Journal
https://www.readbyqxmd.com/read/26876064/should-we-wait-until-severe-pulmonary-hypertension-develops-efficacy-of-percutaneous-mitral-balloon-valvuloplasty-in-patients-with-severe-pulmonary-hypertension-a-subgroup-analysis-of-our-experience
#20
Hakan Ozkan, Tahsin Bozat, Selma Kenar Tiryakioglu, Hasan Ari
BACKGROUND: The primary goal of this study is to evaluate the immediate and long-term ef-fects of percutaneous mitral balloon valvuloplasty (PBMV) on patients with rheumatic mitral stenosis (MS) complicated with severe pulmonary hypertension (PH). METHODS: The study population consisted of 85 patients with MS complicated with severe PH (systolic pulmonary pressure > 75 mm Hg). PBMV was performed with Inoue balloon technique. Clinical and echocardiographic follow-up was scheduled at 6 months and 1 year and yearly thereafter...
2016: Cardiology Journal
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