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Transanal endoscopic microsurgery

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https://www.readbyqxmd.com/read/29850648/increased-rate-of-incidental-colorectal-malignant-polyps-a-single-center-experience
#1
T Buchbjerg, R Kroijer, I Al-Najami, K Urth Hansen, G Baatrup
Background and Aims: To investigate the incidence and treatment of colorectal malignant polyps before and after colorectal cancer screening initiation in March 2014 in a single Danish center. Materials and Methods: 71 patients with colorectal malignant polyps in a single center from 2012 to 2015 were reported retrospectively. Results: There was a significant increase ( P < 0.01) in the incidence of colorectal malignant polyps from 2012 to 2013 and 2014 to 2015 (8 versus 63) relative to the increase in colonoscopies with polypectomy (1029 versus 2706)...
2018: Surgery Research and Practice
https://www.readbyqxmd.com/read/29791891/transanal-endoscopic-microsurgery-with-or-without-completion-total-mesorectal-excision-for-t2-and-t3-rectal-carcinoma
#2
Jeroen W A Leijtens, Thomas W A Koedam, Wernard A A Borstlap, Monique Maas, Pascal G Doornebosch, Tom M Karsten, Eric J Derksen, Laurents P S Stassen, Camiel Rosman, Eelco J R de Graaf, André J A Bremers, Jeroen Heemskerk, Geerard L Beets, Jurriaan B Tuynman, Kevin L J Rademakers
AIM: Transanal endoscopic microsurgery (TEM) is used for the resection of large rectal adenomas and well or moderately differentiated T1 carcinomas. Due to difficulty in preoperative staging, final pathology may reveal a carcinoma not suitable for TEM. Although completion total mesorectal excision is considered standard of care in T2 or more invasive carcinomas, this completion surgery is not always performed. The purpose of this article is to evaluate the outcome of patients after TEM-only, when completion surgery would be indicated...
May 23, 2018: Digestive Surgery
https://www.readbyqxmd.com/read/29725785/salvage-tme-following-tem-a-possible-indication-for-tatme
#3
F Letarte, M Raval, A Karimuddin, P T Phang, C J Brown
BACKGROUND: Salvage surgery after transanal endoscopic microsurgery (TEM) has shown mixed results. Transanal total mesorectal excision (TaTME) might be advantageous in this population. The aim of this study was to assess the short-term oncologic and operative outcomes of salvage surgery after TEM, comparing TaTME to conventional salavge TME (sTME). METHODS: Consecutive patients treated with salvage surgery after TEM were identified. Patients who underwent TaTME were compared to those who had conventional sTME...
May 2018: Techniques in Coloproctology
https://www.readbyqxmd.com/read/29725436/a-small-well-differentiated-rectal-neuroendocrine-tumor-with-multiple-lymph-node-metastases-a-case-report
#4
Seung-Joo Nam, Gi Bong Chae, Seungkoo Lee, Sung Chul Park, Chang Don Kang, Sung Joon Lee
The incidence of rectal neuroendocrine tumor (NET), which is often diagnosed during routine surveillance endoscopy, is increasing. The majority of these tumors are small and asymptomatic, possessing benign features with favorable prognoses. At present, small rectal NETs without high-risk factors are typically treated by local resection, including endoscopic mucosal resection, endoscopic submucosal dissection, or transanal endoscopic microsurgery, with or without additional imaging follow-up by abdominal computed tomography or magnetic resonance imaging...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29709273/how-to-deal-with-rectal-lesions-more-than-15-cm-from-the-anal-verge-through-transanal-endoscopic-microsurgery
#5
Xavier Serra-Aracil, Raquel Gràcia, Laura Mora-López, Sheila Serra-Pla, Anna Pallisera-Lloveras, Maritxell Labró, Salvador Navarro-Soto
BACKGROUND: The aim of this study is to assess postoperative morbidity and mortality in tumors with a proximal margin 15 cm or more from the anal verge operated with transanal endoscopic microsurgery (TEM). METHODS: This observational study of consecutive rectal tumor patients undergoing TEM was carried out from July 2004 to June 2017. We compared the results of rectal tumors at distances of ≥15 cm (group A) and <15 cm (group B) from the anal verge. RESULTS: During the study period 667 patients were included: 118 in group A and 549 in group B...
April 22, 2018: American Journal of Surgery
https://www.readbyqxmd.com/read/29668359/laparoscopic-total-mesorectal-excision-following-transanal-endoscopic-microsurgery-for-rectal-cancer
#6
Nidal Issa, Yaniv Fenig, Rachel Gingold-Belfer, Muhammad Khatib, Wisam Khoury, Lea Wolfson, Hemda Schmilovitz-Weiss
BACKGROUND: Patients' selection for transanal endoscopic microsurgery (TEM) depends on diagnostic modalities; however, there are still some limitations in the preoperative diagnosis of rectal lesions, and in some reports, up to third of the adenomas resected by TEM were found to be adenocarcinoma; therefore, salvage radical resection (RR) remains necessary for achieving oncological resection. Salvage RR may encounter some technical problems as the violation of the mesorectum and the scar formation...
April 18, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29658675/local-excision-for-rectal-cancer-a-minimally-invasive-option
#7
Marco E Allaix, Alberto Arezzo, Milica Nestorović, Bianca Galosi, Mario Morino
Transanal excision (TAE) with conventional retractors and transanal endoscopic microsurgery (TEM) are two well established minimally invasive surgical options for the treatment of selected rectal cancers. TEM is nowadays considered the standard of care for the transanal excision of rectal tumors, since it is associated with significantly better quality of excision and lower rates of recurrence than TAE. When compared with rectal resection and total mesorectal excision, TEM has lower postoperative morbidity and better functional outcomes, with similar long-term survival rates in selected early rectal cancers...
April 13, 2018: Minerva Chirurgica
https://www.readbyqxmd.com/read/29599303/radiotherapy-may-offer-a-recurrence-and-survival-benefit-in-rectal-cancers-treated-surgically-with-transanal-endoscopic-microsurgery-a-systematic-review-and-meta-analysis
#8
REVIEW
Michail Sideris, Ana Nora Donaldson, John Hanrahan, Matthew Grunwald, Savvas Papagrigoriadis
BACKGROUND/AIM: Several studies report outcomes of Transanal Endoscopic Microsurgery (TEMS) surgery in combination with radiotherapy, however the combination of those treatments is provided mostly on an adhoc individual basis and the role of radiotherapy remains unclear. The aim of this study was to identify the effect of neo-adjuvant or adjuvant radiotherapy in the oncological outcomes of rectal cancer treated surgically with TEMS. MATERIALS AND METHODS: We performed a systematic review of the literature on MEDLINE and Pubmed databases...
April 2018: Anticancer Research
https://www.readbyqxmd.com/read/29516708/effectiveness-of-spinal-anaesthesia-in-transanal-endoscopic-microsurgery-a-3-years-experience
#9
Gerardo Cortese, Gabriele Sales, Giorgia Maiolo, Mario Morino, Martina Scanu, Luca Brazzi
BACKGROUND: The feasibility and safety of transanal endoscopic microsurgery (TEM) performed under spinal anaesthesia (SA) has been recently demonstrated. This retrospective study compared the differences in opioid consumption and postoperative recovery in patients undergoing TEM under GA and SA. METHODS: All consecutive patients who underwent TEM at 'Città della Salute e della Scienza' hospital of Turin (Italy) between January 2012 and December 2015 were enrolled...
March 7, 2018: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29508218/comparative-quality-of-life-in-patients-following-transanal-minimally-invasive-surgery-and-healthy-control-subjects
#10
Stefan H E M Clermonts, Yu-Ting van Loon, Dareczka K Wasowicz, Barbara S Langenhoff, David D E Zimmerman
BACKGROUND: Transanal minimally invasive surgery (TAMIS) is considered the successor of transanal endoscopic microsurgery (TEMS). It makes use of more readily available laparoscopic instruments and single-port access platforms with similar perioperative, clinical and oncological outcomes. Little is known about quality of life (QoL) outcomes after the use of TAMIS. The aim of this study was to assess QoL after TAMIS in our patients and compare this with QoL in the healthy Dutch population...
March 5, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29470728/fecal-incontinence-after-transanal-endoscopic-microsurgery
#11
Matas Jakubauskas, Valdemaras Jotautas, Eligijus Poskus, Saulius Mikalauskas, Gintare Valeikaite-Tauginiene, Kestutis Strupas, Tomas Poskus
PURPOSE: Transanal endoscopic microsurgery (TEM) procedure could potentially influence the development of fecal incontinence later in life. The aim of our study was to assess long-term functional outcomes after TEM and to determine possible variables related to incontinence. METHODS: Patients, enrolled in a prospectively collected TEM operation database, were interviewed using a postal questionnaire. The questionnaire consisted of EuroQol (EQ)-5D-5L quality of life questionnaire, Wexner fecal incontinence grading scale, and additional questions about other perianal operations and obstetric history for women...
April 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29448984/transanal-endoscopic-microsurgery-treatment-of-twice-recurred-tail-gut
#12
Pilar Hernandez Casanovas, Jesus Bollo Rodriguez, Carmen Martinez Sanchez, Juan Carlos Pernas Canadell, Eduard Maria Targarona Soler
No abstract text is available yet for this article.
February 12, 2018: Cirugía Española
https://www.readbyqxmd.com/read/29390320/local-resection-of-rectal-neuroendocrine-tumor-with-first-clinical-manifestation-of-giant-liver-metastasis-by-transanal-endoscopic-microsurgery-a-case-report
#13
Gang Xu, Peipei Wang, Yao Xiao, Xin Wu, Guole Lin
RATIONALE: Rectal neuroendocrine tumor (NET) is a relatively rare tumor. Well-differentiated NETs (G1 and G2) rarely display distant metastasis at initial diagnosis. Currently, treatment for the primary lesions of rectal NETs with liver metastasis remains controversial. The liver metastasis was resected in local hospital. Transanal endoscopic microsurgery (TEM) has emerged as an effective minimally invasive surgery for local resection of lower rectal lesions. Herein, we reported the initial application of TEM to remove the rectal primary lesion in patients with low rectal NETs (G2) with giant liver metastases...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29388060/how-is-rectal-cancer-managed-a-survey-exploring-current-practice-patterns-in-canada
#14
A Crawford, J Firtell, A Caycedo-Marulanda
INTRODUCTION: Locally advanced rectal cancers are most often treated with neoadjuvant chemoradiation followed by surgical resection. However, there are differing opinions surrounding management of rectal cancer, including a lack of consensus on the optimal time interval between chemoradiation and surgery, and the management of patients with complete clinical response following neoadjuvant therapy. This study seeks to summarize management trends for rectal cancer among a sample of Canadian surgeons...
February 1, 2018: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/29383191/comparison-of-transanal-endoscopic-microsurgery-with-or-without-neoadjuvant-therapy-and-standard-total-mesorectal-excision-in-the-treatment-of-clinical-t2-low-rectal-cancer-a-meta-analysis
#15
Zheng-Shui Xu, Hua Cheng, Yuhong Xiao, Jia-Qing Cao, Fei Cheng, Wen-Ji Xu, Jia-Qi Ying, Jun Luo, Wei Xu
Some clinical trials demonstrated local resection for clinical T1 rectal cancer was safe and effective. But for clinical T2 rectal cancer, the results were controversial. Neoadjuvant therapy (NT) is proven to reduce the opportunity of advanced rectal cancer recurrence in various researches. The objective of this Meta-Analysis was to evaluate the oncological outcomes of transanal endoscopic microsurgery (TEM) with or without NT comparing with conventional total mesorectal excision (TME) for the treatment of clinical T2 rectal cancer...
December 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/29363859/modern-management-of-t1-rectal-cancer-by-tem-a-ten-year-single-centre-experience
#16
H J S Jones, R Hompes, N Mortensen, C Cunningham
AIM: Minimally-invasive, organ-sparing surgery has been used increasingly for early rectal cancer in recent years. However local recurrence remains a concern. This study presents a ten-year single-centre experience of recurrence after local excision for T1 rectal cancer. METHOD: Data are collected prospectively on all patients undergoing local excision by transanal endoscopic microsurgery (TEM) in a single institution. Data covering a 10-year period were analysed...
January 24, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29288615/synchronous-locally-advanced-rectal-cancer-with-clinical-complete-remission-and-important-downstaging-after-neoadjuvant-radiochemotherapy-personalised-therapeutic-approach
#17
Dragoş Eugen Georgescu, Mihai Teodor Georgescu, Florin Teodor Bobircă, Teodor Florin Georgescu, Horia Doran, Traian Pătraşcu
Introduction: The current practice for patients with good response, important downstaging or complete remission after preoperative chemoradiation, is to perform surgery on the basis of initial pretherapeutical staging. In literature, varying approaches, like transanal endoscopic microsurgery and even "wait and see", are described for patients with good response after chemoradiation. However, considering the present level of available evidence, the wide-spread adoption of a "watch and wait" policy in those achieving a complete clinical remission cannot be justified...
November 2017: Chirurgia
https://www.readbyqxmd.com/read/29288190/can-we-s-ave-the-rectum-by-watchful-waiting-or-t-rans-a-nal-microsurgery-following-chemo-r-adiotherapy-versus-t-otal-mesorectal-excision-for-early-re-ctal-c-ancer-star-trec-study-protocol-for-a-multicentre-randomised-feasibility-study
#18
Anouk J M Rombouts, Issam Al-Najami, Natalie L Abbott, Ane Appelt, Gunnar Baatrup, Simon Bach, Aneel Bhangu, Karen-Lise Garm Spindler, Richard Gray, Kelly Handley, Manjinder Kaur, Ellen Kerkhof, Camilla Jensenius Kronborg, Laura Magill, Corrie A M Marijnen, Iris D Nagtegaal, Lars Nyvang, Femke P Peters, Per Pfeiffer, Cornelis Punt, Philip Quirke, David Sebag-Montefiore, Mark Teo, Nick West, Johannes H W de Wilt
INTRODUCTION: Total mesorectal excision (TME) is the highly effective standard treatment for rectal cancer but is associated with significant morbidity and may be overtreatment for low-risk cancers. This study is designed to determine the feasibility of international recruitment in a study comparing organ-saving approaches versus standard TME surgery. METHODS AND ANALYSIS: STAR-TREC trial is a multicentre international randomised, three-arm parallel, phase II feasibility study in patients with biopsy-proven adenocarcinoma of the rectum...
December 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/29237142/transanal-endoscopic-microsurgery-for-patients-with-rare-rectal-tumors
#19
Xin Wu, Guole Lin, Huizhong Qiu, Jiaolin Zhou
BACKGROUND: Transanal endoscopic microsurgery (TEM) has been accepted worldwide for the treatment of local rectal lesions. Rare rectal tumors consist of several different types of malignant or benign tumors. Surgical management is considered to be the only curative option. The aim of this study is to investigate the role of TEM in the treatment of rare rectal tumors. MATERIALS AND METHODS: A total of 147 patients with rare rectal tumors underwent TEM in our center from April 2006 to May 2017...
May 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29234923/non-inferiority-multicenter-prospective-randomized-controlled-study-of-rectal-cancer-t-2-t-3s-superficial-n-0-m-0-undergoing-neoadjuvant-treatment-and-local-excision-tem-vs-total-mesorectal-excision-tme
#20
X Serra-Aracil, C Pericay, T Golda, L Mora, E Targarona, S Delgado, A Reina, F Vallribera, J M Enriquez-Navascues, S Serra-Pla, J C Garcia-Pacheco
PURPOSE: The standard treatment of rectal adenocarcinoma is total mesorectal excision (TME), in many cases requires a temporary or permanent stoma. TME is associated with high morbidity and genitourinary alterations. Transanal endoscopic microsurgery (TEM) allows access to tumors up to 20 cm from the anal verge, achieves minimal postoperative morbidity and mortality rates, and does not require an ostomy. The treatment of T2, N0, and M0 cancers remains controversial. Preoperative chemoradiotherapy (CRT) in association with TEM reduces local recurrence and increases survival...
February 2018: International Journal of Colorectal Disease
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