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Axillary lymph node dissection

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https://www.readbyqxmd.com/read/28919032/the-role-of-preoperative-axillary-ultrasound-and-fine-needle-aspiration-cytology-in-identifying-patients-with-extensive-axillary-lymph-node-involvement
#1
Robert Maráz, Tamás Zombori, Éva Ambrózay, Gábor Cserni
INTRODUCTION: In the recent past, both clinically node-positive and node-negative but sentinel node-positive patients underwent axillary lymph node dissection (ALND), although the two groups seem to have substantially different degree of nodal involvement. METHODS: Data on consecutive primary breast cancer patients with documented axillary ultrasound (AXUS) results who underwent ALND between January 2003 and December 2015 either because of AXUS-guided fine needle aspiration (A-FNAC) results or because of a positive sentinel lymph node were retrospectively analysed...
August 30, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28918186/health-related-quality-of-life-in-melanoma-patients-impact-of-melanoma-related-limb-lymphoedema
#2
Caroline A Gjorup, Mogens Groenvold, Helle W Hendel, Karin Dahlstroem, Krzysztof T Drzewiecki, Tobias W Klausen, Lisbet R Hölmich
AIM: To explore health-related quality of life (HRQoL) in recurrence-free melanoma patients, with a focus on the association between melanoma-related limb lymphoedema and HRQoL. METHODS: HRQoL was evaluated using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), the breast cancer module (EORTC QLQ-BR23) subscales body image and future perspective, the Functional Assessment for Cancer Therapy-General subscale social/family well-being and the Hospital Anxiety and Depression Scale...
September 14, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28917551/-impact-of-the-preservation-of-the-branches-of-intercostobrachial-nerve-on-the-quality-of-life-of-patients-operated-for-a-breast-cancer
#3
Zenaba Saleh, Julia Salleron, Sandrine Baffert, Alain Paveau, Jean-Marc Classe, Frédéric Marchal
AIM: The aim of this study was to assess the impact of the preservation of the intercostobrachial nerve on the quality of life of patients operated for breast cancer. METHODS: This study was ancillary to cost comparison study of axillary sentinel lymph node detection and axillary lymphadenectomy in early breast cancer. It was a prospective multicenter, observational, non-randomized study. The quality of life was assessed using two questionnaires: QLQ-C30 and specific module QLQ-BR23 Surveys have been performed before initiation of surgery, one week, and 1 month, 8 months and 12 months after discharge from hospitalization for the first surgical procedure...
September 13, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28914693/care-patterns-and-changes-in-treatment-for-nonmetastatic-breast-cancer-in-2013-2014-versus-2005-a-population-based-high-resolution-study
#4
Marcela Guevara, Rosana Burgui, Jorge Díaz-González, Esteban Salgado, Francisco Vicente, Conchi Moreno-Iribas, María J Urbina, Alicia Córdoba, Concepción de Miguel, Eva Ardanaz
Studies on recent trends in patterns of care for breast cancer patients are scarce. This study aims to examine the patterns and trends in the treatment of women with nonmetastatic breast cancer according to major recommended treatment options. A population-based study was carried out in Navarra, Spain, including all women with a primary invasive nonmetastasized breast cancer, diagnosed in 2005 and in 2013-2014. We compared patients' characteristics and treatment patterns between periods. Factors associated with receipt of recommended treatment were examined by multivariate logistic regression...
September 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28898379/effect-of-axillary-dissection-vs-no-axillary-dissection-on-10-year-overall-survival-among-women-with-invasive-breast-cancer-and-sentinel-node-metastasis-the-acosog-z0011-alliance-randomized-clinical-trial
#5
Armando E Giuliano, Karla V Ballman, Linda McCall, Peter D Beitsch, Meghan B Brennan, Pond R Kelemen, David W Ollila, Nora M Hansen, Pat W Whitworth, Peter W Blumencranz, A Marilyn Leitch, Sukamal Saha, Kelly K Hunt, Monica Morrow
Importance: The results of the American College of Surgeons Oncology Group Z0011 (ACOSOG Z0011) trial were first reported in 2005 with a median follow-up of 6.3 years. Longer follow-up was necessary because the majority of the patients had estrogen receptor-positive tumors that may recur later in the disease course (the ACOSOG is now part of the Alliance for Clinical Trials in Oncology). Objective: To determine whether the 10-year overall survival of patients with sentinel lymph node metastases treated with breast-conserving therapy and sentinel lymph node dissection (SLND) alone without axillary lymph node dissection (ALND) is noninferior to that of women treated with axillary dissection...
September 12, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28894513/diagnostic-methods-risk-factors-prevention-and-management-of-breast-cancer-related-lymphedema-past-present-and-future-directions
#6
Hoda E Sayegh, Maria S Asdourian, Meyha N Swaroop, Cheryl L Brunelle, Melissa N Skolny, Laura Salama, Alphonse G Taghian
PURPOSE OF REVIEW: Breast cancer-related lymphedema (BCRL) is a chronic, adverse, and much feared complication of breast cancer treatment, which affects approximately 20% of patients following breast cancer treatment. BCRL has a tremendous impact on breast cancer survivors, including physical impairments and significant psychological consequences. The intent of this review is to discuss recent studies and analyses regarding the risk factors, diagnosis, prevention through early screening and intervention, and management of BCRL...
June 2017: Current Breast Cancer Reports
https://www.readbyqxmd.com/read/28890124/-sentinel-lymph-node-biopsy-and-neoadjuvant-treatment-in-breast-cancer
#7
REVIEW
Martha Duraes, Eugénie Guillot, Julien Seror, Nicolas Pouget, Roman Rouzier
Sentinel lymph node biopsy has replaced axillary lymph node dissection in those patients with clinically node-negative axilla without compromising their oncologic outcomes. Indication of neoadjuvant chemotherapy has been extended to patients to evaluate the pathologic response and to offer more conservative breast surgery. Sentinel lymph node dissection after neoadjuvant chemotherapy is feasible and accurate in patients with clinically node-negative patients. The timing of the sentinel lymph node biopsy, before or after medical treatment has been studied with benefits for each procedure...
September 7, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28888915/a-case-report-of-locally-advanced-triple-negative-breast-cancer-showing-pathological-complete-response-to-weekly-paclitaxel-with-bevacizumab-treatment-following-disease-progression-during-anthracycline-based-neoadjuvant-chemotherapy
#8
Hideo Shigematsu, Shinji Ozaki, Daisuke Yasui, Taizo Hirata
INTRODUCTION: Neoadjuvant chemotherapy (NAC) is the standard of care for locally advanced triple negative breast cancer, however, approximately 5% of cases show disease progression during NAC. Although downstaging is essential to create an opportunity for curative surgery and to improve the local control outcome in such a case, no additional line of chemotherapy has been established. CASE PRESENTATION: A 60-year-old woman was referred to our hospital for an axillary mass presenting three weeks ago and was diagnosed as having right locally advanced (T2N2M0, stage IIIA) triple negative breast cancer...
September 1, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28888579/reliability-of-self-reported-treatment-data-by-patients-with-breast-cancer-compared-with-medical-record-data
#9
Melissa Kool, Esther Bastiaannet, Cornelis J H Van de Velde, Perla J Marang-van de Mheen
OBJECTIVES: Medical records are considered the gold standard for accurate treatment information. However, treatment data are increasingly obtained from questionnaires. It can be questioned whether self-reported treatment data are reliable, particularly because patients have to process a lot of information during their diagnosis and treatment process. The present study assesses the reliability of self-reported treatment data compared with medical records. METHODS: All patients with stage I, II, and III breast cancer (n = 606) in 5 hospitals in the west of the Netherlands were invited to complete a questionnaire 9 to 18 months after surgery...
August 18, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28885862/volume-and-tissue-composition-changes-measured-with-dual-energy-x-ray-absorptiometry-in-melanoma-related-limb-lymphedema
#10
Caroline A Gjorup, Helle W Hendel, Bo Zerahn, Karin Dahlstroem, Krzysztof T Drzewiecki, Tobias W Klausen, Lisbet Rosenkrantz Hölmich
Abstracts Background: The aim of this cross-sectional study was to investigate the volume, fat mass, and lean mass in both upper and lower limbs measured with dual-energy X-ray absorptiometry (DXA) in melanoma patients with melanoma-related limb lymphedema. METHODS AND RESULTS: Four hundred thirty-one patients who had undergone surgical treatment with wide local excision and unilateral axillary or inguinal sentinel lymph node biopsy and/or complete lymph node dissection participated in a survey, and they underwent clinical examination and measurements of their upper or lower limbs with DXA...
September 8, 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28879416/patient-age-and-tumor-subtype-predict-the-extent-of-axillary-surgery-among-breast-cancer-patients-eligible-for-the-american-college-of-surgeons-oncology-group-trial-z0011
#11
Cecilia T Ong, Samantha M Thomas, Rachel C Blitzblau, Oluwadamilola M Fayanju, Tristen S Park, Jennifer K Plichta, Laura H Rosenberger, Terry Hyslop, E Shelley Hwang, Rachel A Greenup
BACKGROUND: The American College of Surgeons Oncology Group (ACOSOG) Z0011 trial established the safety of omitting axillary lymph node dissection (ALND) for early-stage breast cancer patients with limited nodal disease undergoing lumpectomy. We examined the extent of axillary surgery among women eligible for Z0011 based on patient age and tumor subtype. METHODS: Patients with cT1-2, cN0 breast cancers and one or two positive nodes diagnosed from 2009 to 2014 and treated with lumpectomy were identified in the National Cancer Data Base...
September 6, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28877063/sentinel-lymph-nodes-in-classic-invasive-lobular-carcinoma-of-the-breast-cytokeratin-immunostain-ensures-detection-and-precise-determination-of-extent-of-involvement
#12
Ami Patel, Timothy D'Alfonso, Esther Cheng, Syed A Hoda
The assessment of sentinel lymph nodes (SLN) on hematoxylin and eosin (H&E)-stained sections in cases of classic type of invasive lobular carcinoma (cILC) is considered unreliable, particularly in cases with minimal involvement, that is by either isolated tumor cells (pN0i+) or micrometastases (pN1mi). Although the impact of minimal SLN involvement has been shown to be insignificant in most clinical trials (even though cILC was either under-represented or not separated in the respective cohorts), the results of MIRROR trial did emphasize the need for additional therapy in cases with minimally involved SLN to ensure improved disease-free survival...
September 4, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28876628/axillary-lymph-node-dissection-in-invasive-breast-cancer-patients-at-charlotte-maxeke-johannesburg-academic-hospital-and-chris-hani-baragwanath-academic-hospital
#13
C Groenewald, S Neitz, H Cubasch, A Mannell
BACKGROUND: Axillary lymph node dissection (ALND) carries a high morbidity and sentinel node biopsy has become the standard of care in node-negative disease. Patients in our setting are assessed as node-positive on the basis of physical examination and axillary ultrasound and will undergo ALND without prior biopsy. The administration of neoadjuvant chemotherapy (NACT) may downstage the axilla and offer opportunities for axilla-sparing surgery. METHOD: This retrospective cohort study included all female patients older than 18 years of age who underwent axillary surgery in the breast units at Charlotte Maxeke Johannesburg Academic Hospital and Chris Hani Baragwanath Academic Hospital from March 2013 to March 2015...
June 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
https://www.readbyqxmd.com/read/28874902/lymph-node-retrieval-rates-in-melanoma-a-quality-assessment-parameter
#14
D Berger-Richardson, E Cordeiro, M Ernjakovic, A M Easson
INTRODUCTION: Regional lymph node dissection (rlnd) for melanoma with nodal metastasis is a specialized procedure that is associated with improved disease-specific survival in selected patients. Furthermore, there is evidence that a higher lymph node retrieval rate (lnrr) is associated with improved local control. Currently, no consensus has been reached on the definition of an adequate lnrr. A minimum lnrr has been proposed as a quality assessment parameter that has to be validated. METHODS: We conducted a retrospective cohort analysis at the Princess Margaret Cancer Centre (University Health Network, Toronto, ON)...
August 2017: Current Oncology
https://www.readbyqxmd.com/read/28868019/cystoid-macular-edema-during-treatment-with-paclitaxel-and-bevacizumab-in-a-patient-with-metastatic-breast-cancer-a-case-report-and-literature-review
#15
Takamichi Yokoe, Ippei Fukada, Kokoro Kobayashi, Tomoko Shibayama, Yumi Miyagi, Atsushi Yoshida, Takuji Iwase, Shinji Ohno, Yoshinori Ito
We present a case of a metastatic breast cancer patient with cystoid macular edema (CME) occurring during treatment with paclitaxel and bevacizumab. She had a history of neoadjuvant chemotherapy and partial mastectomy plus axillary lymph node dissection for stage IIB left-breast cancer. Twenty-four months later, she was diagnosed with multiple bone metastases and underwent chemotherapy with paclitaxel and bevacizumab. Thirty-three months after the initiation of the chemotherapy, she noticed bilateral blurred vision...
May 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28862120/does-the-surgical-management-of-the-intercostobrachial-nerve-influence-the-postoperatory-paresthesia-of-the-upper-limb-and-life-quality-in-breast-cancer-patients
#16
Hankó-Bauer Orsolya, Marius Florin Coros, Simona Stolnicu, Adrian Naznean, Rares Georgescu
The aim of our study was to evaluate the extent to which the preservation or the section of the intercostobrachial nerve (ICBN) influences the development of postoperatoryparesthesia and to assess whether the development of paresthesiamay change the patient's life quality after surgical treatment for breast carcinoma. MATERIAL AND METHODS: We performed a nonrandomized retrospective study including 100 patients who underwent axillary lymph node dissection for infiltrating breast carcinoma associated with axillary lymph node metastases...
July 2017: Chirurgia
https://www.readbyqxmd.com/read/28854395/sentinel-node-biopsy-in-early-breast-cancer-a-review-on-recent-and-ongoing-randomized-trials
#17
REVIEW
Emanuela Esposito, Rosa Di Micco, Oreste D Gentilini
INTRODUCTION: Sentinel Lymph Node Biopsy (SLNB) is regarded as the standard procedure for nodal staging in patients with early breast cancer. In the last decade several randomized trials have been evaluating its role and indications. MATERIALS AND METHODS: This article reviews recent and ongoing randomized trials on SLNB. RESULTS: Four randomized controlled trials have recently shown evidence that SLNB either alone or followed by radiation therapy is effective for the management in patients with low axillary tumor burden in early breast cancer...
August 27, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28843225/managing-the-axilla-in-early-breast-cancer-impact-of-acosog-z0011-trial-in-changing-practices-in-a-low-middle-income-country
#18
Awais Amjad Malik, Namra Urooj, Romaisa Shamim, Mariam Salim, Razia Bano, Zulqurnain Chaudhry, Huma Majeed Khan, Amina Iqbal Khan
Objective: To determine the impact of the trial on surgeon practice patterns at our institution. Methodology: A comparison of patients undergoing surgery for early breast cancer before and after the implementation of the new guidelines was done. We adopted the new guidelines in April 2015. Patients meeting Z0011 inclusion criteria were identified. For group A (Pre Z0011) patients operated between Jan to Dec 2013 were studied. And for Group B (Post Z0011) patients operated between July 2014 to Jun 2015 were included...
August 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28831632/utilization-of-bioimpedance-spectroscopy-in-the-prevention-of-chronic-breast-cancer-related-lymphedema
#19
David I Kaufman, Chirag Shah, Frank A Vicini, Marisa Rizzi
BACKGROUND: This analysis was performed to assess the impact of early intervention following prospective surveillance using bioimpedance spectroscopy (BIS) to detect and manage breast cancer-related lymphedema (BCRL). METHODS: From 8/2010 to 12/2016, 206 consecutive patients were evaluated with BIS. The protocol included pre-operative assessment with L-Dex as well as post-operative assessments at regular intervals. Patients with L-Dex scores >10 from baseline were considered to have subclinical BCRL and were treated with over-the-counter (OTC) compression sleeve for 4 weeks...
August 22, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28830644/ultrasound-guided-fine-needle-aspiration-of-non-palpable-and-suspicious-axillary-lymph-nodes-with-subsequent-removal-after-tattooing-false-negative-results-and-concordance-with-sentinel-lymph-nodes
#20
Won Hwa Kim, Hye Jung Kim, Jin Hyang Jung, Ho Yong Park, Jeeyeon Lee, Wan Wook Kim, Ji Young Park, Hyejin Cheon, So Mi Lee, Seung Hyun Cho, Kyung Min Shin, Gab Chul Kim
Ultrasonography-guided fine-needle aspiration (US-guided FNA) for axillary lymph nodes (ALNs) is currently used with various techniques for the initial staging of breast cancer and tagging of ALNs. With the implementation of the tattooing of biopsied ALNs, the rate of false-negative results of US-guided FNA for non-palpable and suspicious ALNs and concordance with sentinel lymph nodes were determined by node-to node analyses. A total of 61 patients with breast cancer had negative results for metastasis on US-guided FNA of their non-palpable and suspicious ALNs...
August 19, 2017: Ultrasound in Medicine & Biology
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