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https://www.readbyqxmd.com/read/28640147/human-photoreceptor-cone-density-measured-with-adaptive-optics-technology-rtx1-device-in-healthy-eyes-standardization-of-measurements
#1
Anna Zaleska-Żmijewska, Zbigniew M Wawrzyniak, Magdalena Ulińska, Jerzy Szaflik, Anna Dąbrowska, Jacek P Szaflik
The anatomic structures of the anterior segment of the eye enable correct reception of stimuli by the retina, which contains receptors that receive light impulses and transmit them to the visual cortex. The aim of this study was to assess the effect of the size of the sampling window in an adaptive optics (AO) flood-illumination retinal camera (rtx1) on cone density measurements in the eyes of healthy individuals and to investigate the differences in cone density and spacing in different quadrants of the retina...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28632734/choroidal-thickness-in-patients-with-coronary-artery-disease
#2
Meleha Ahmad, Patrick A Kaszubski, Lucy Cobbs, Harmony Reynolds, Roland Theodore Smith
PURPOSE: To evaluate choroidal thickness (CTh) in patients with coronary artery disease (CAD) compared to healthy controls. DESIGN: Cross-sectional. METHODS: Setting: Ambulatory clinic of a large city hospital. Patient population: Thirty-four patients had documented CAD, defined as history of >50% obstruction in at least one coronary artery on cardiac catheterization, positive stress test, ST elevation myocardial infarction, or revascularization procedure...
2017: PloS One
https://www.readbyqxmd.com/read/28632403/effect-of-amblyopia-treatment-on-choroidal-thickness-in-children-with-hyperopic-anisometropic-amblyopia
#3
Seray Aslan Bayhan, Hasan Ali Bayhan
PURPOSE: To evaluate choroidal thickness (CT) in the eyes of children with hyperopic anisometropic amblyopia and to assess changes in CT during amblyopia treatment using spectral-domain optical coherence tomography (SD-OCT). METHODS: This longitudinal study, initially enrolled 40 patients, aged 3-9 years with hyperopic anisometropic amblyopia. Patients underwent treatment with refractive correction alone for 16 weeks and if needed, with refractive correction and patching treatment thereafter (6 months)...
June 20, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28628004/visual-field-map-clusters-in-human-frontoparietal-cortex
#4
Wayne E Mackey, Jonathan Winawer, Clayton E Curtis
The visual neurosciences have made enormous progress in recent decades, in part because of the ability to drive visual areas by their sensory inputs, allowing researchers to reliably define visual areas across individuals and across species. Similar strategies for parcellating higher-order cortex have proven elusive. Here, using a novel experimental task and nonlinear population receptive field modeling we map and characterize the topographic organization of several regions in human frontoparietal cortex. We discover representations of both polar angle and eccentricity that are organized into clusters, similar to visual cortex, where multiple gradients of polar angle of the contralateral visual field share a confluent fovea...
June 19, 2017: ELife
https://www.readbyqxmd.com/read/28617854/choroidal-thickness-in-school-children-the-gobi-desert-children-eye-study
#5
Dan Zhu, Yan Wang, Yan Fei Zheng, Da Yong Yang, Kai Guo, Xian Rong Yang, Xin Xia Jing, Ian Y Wong, Qi Sheng You, Yong Tao, Jost B Jonas
PURPOSE: To investigate choroidal thickness (CT) and its associations in children in a school-based study. METHODS: The cross-sectional school-based Gobi Desert Children Eye Study included 1565 out of 1911 (81.9%) eligible children from all schools in the oasis region of Ejina in the Gobi Desert. A detailed ophthalmic examination was performed, including spectral-domain optical coherence tomography with enhanced depth imaging for CT measurement. RESULTS: CT measurements were available for 1463 (93...
2017: PloS One
https://www.readbyqxmd.com/read/28616716/retinal-microstructures-are-altered-in-patients-with-idiopathic-infantile-nystagmus
#6
Jinu Han, Taekjune Lee, Jong Bok Lee, Sueng-Han Han
PURPOSE: To compare segmented retinal layer thicknesses between patients with idiopathic infantile nystagmus (IIN) and controls. METHODS: This retrospective case-control study included 66 patients with IIN and 66 age-matched controls. The retinal layers were examined using spectral domain optical coherence tomography with autosegmentation. Central foveal thickness (CFT), outer nuclear layer (ONL), and outer segment length (OSL) thickness were measured at the fovea center...
June 14, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28614138/acute-exudative-paraneoplastic-polymorphous-vitelliform-maculopathy-during-vemurafenib-and-pembrolizumab-treatment-for-metastatic-melanoma
#7
Harpal S Sandhu, Anton M Kolomeyer, Marisa K Lau, Carol L Shields, Lynn M Schuchter, Charles W Nichols, Tomas S Aleman
PURPOSE: To describe a patient with BRAF mutation-positive cutaneous melanoma who developed acute exudative polymorphous vitelliform maculopathy during vemurafenib and pembrolizumab treatment for metastatic melanoma. METHODS: Retrospective case report documented with wide-field fundus imaging, spectral domain optical coherence tomography, and fundus autofluorescence imaging. RESULTS: A 55-year-old woman with bilateral ductal breast carcinoma and BRAF mutation-positive metastatic cutaneous melanoma complained of bilateral blurred vision within 5 days of starting vemurafenib (BRAF inhibitor)...
June 13, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28613354/the-quantitative-measurements-of-vascular-density-and-flow-areas-of-macula-using-optical-coherence-tomography-angiography-in-normal-volunteers
#8
Fariba Ghassemi, Kaveh Fadakar, Fatemeh Bazvand, Reza Mirshahi, Masoumeh Mohebbi, Siamak Sabour
BACKGROUND AND OBJECTIVE: The quantification of the density of macular vascular networks and blood flow areas in the foveal and parafoveal area in healthy subjects using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: Cross-sectional, prospective study in an institutional setting at the Retina Services of Farabi Eye Hospital. One hundred twelve normal volunteers with no known ocular or systemic disease were included, including patient numbers (one or both eyes), selection procedures, inclusion/exclusion criteria, randomization procedure, and masking...
June 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28613219/repeatability-of-automated-vessel-density-and-superficial-and-deep-foveal-avascular-zone-area-measurements-using-optical-coherence-tomography-angiography-diurnal-findings
#9
Özge Yanik Odabaş, Sibel Demirel, Emin Özmert, Figen Batıoğlu
PURPOSE: To evaluate the repeatability of vessel density and superficial and deep foveal avascular zone measurements using optical coherence tomography angiography, and to specify a diurnal change range. METHODS: Forty-six eyes of 25 healthy individuals were included. Optical coherence tomography angiography measurements were planned for three consecutive sessions, with 3 hours in between them. AngioVue software of the RTVue XR Avanti was used. Superficial and deep retinal layer vessel density values, including the whole retina, fovea, and each parafoveal zone, were obtained from the software...
May 2, 2017: Retina
https://www.readbyqxmd.com/read/28611649/a-case-of-diabetic-macular-edema-with-prominent-chorioretinal-folds
#10
Takaki Sato, Ryohsuke Kohmoto, Masanori Fukumoto, Seita Morishita, Daisaku Kimura, Kensuke Tajiri, Takatoshi Kobayashi, Teruyo Kida, Shota Kojima, Tsunehiko Ikeda
PURPOSE: To report a case of diabetic macular edema with prominent chorioretinal folds. CASE REPORT: This study involved a 55-year-old male with untreated bilateral diabetic retinopathy who had undergone cataract surgery at another clinic. Following that surgery, diabetic macular edema rapidly exacerbated, accentuating marked cystoid macular edema and radial chorioretinal folds in the macula. Investigation of his medical history revealed that in addition to diabetes, he had uncontrolled hypertension and severe diabetic nephropathy...
January 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28609917/first-record-of-spiral-i-fovea-i-i-amphidialis-i-in-i-acantholaimus-i-chromadoridae-%C3%A2-nematoda-with-a-description-of-a-new-species-from-shallow-sediments-of-the-south-atlantic-and-an-emended-diagnosis-of-the-genus
#11
Alex Manoel, Maria Cristina DA Silva, André M Esteves
A new species of the genus Acantholaimus is described from the South Atlantic, in the Potiguar Basin off the continental shelf of northeast Brazil. Acantholaimus marliae sp. n. is characterized by the long body; numerous somatic setae arranged in four sublateral longitudinal rows; buccal cavity with five solid teeth (four subventral and one dorsal), with the largest tooth dorsally located and the most protuberant between the subventral teeth shaped similarly to a "bottle opener"; and spiral fovea amphidialis...
April 28, 2017: Zootaxa
https://www.readbyqxmd.com/read/28595892/localization-of-optic-disc-and-fovea-in-retinal-images-using-intensity-based-line-scanning-analysis
#12
Ravi Kamble, Manesh Kokare, Girish Deshmukh, Fawnizu Azmadi Hussin, Fabrice Mériaudeau
Accurate detection of diabetic retinopathy (DR) mainly depends on identification of retinal landmarks such as optic disc and fovea. Present methods suffer from challenges like less accuracy and high computational complexity. To address this issue, this paper presents a novel approach for fast and accurate localization of optic disc (OD) and fovea using one-dimensional scanned intensity profile analysis. The proposed method utilizes both time and frequency domain information effectively for localization of OD...
April 27, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28595625/blood-flow-velocity-and-thickness-of-the-choroid-in-a-patient-with-chorioretinopathy-associated-with-ocular-blunt-trauma
#13
Yuri Ishikawa, Yuki Hashimoto, Wataru Saito, Ryo Ando, Susumu Ishida
BACKGROUND: Choroidal circulation hemodynamics in eyes with ocular blunt trauma has not been quantitatively examined yet. We quantitatively examined changes in choroidal blood flow velocity and thickness at the lesion site using laser speckle flowgraphy (LSFG) and enhanced depth imaging optical coherence tomography (EDI-OCT) in a patient with chorioretinopathy associated with ocular blunt trauma. CASE PRESENTATION: A 13-year-old boy developed a chorioretinal lesion with pigmentation extending from the optic disc to the superotemporal side in the right eye after ocular blunt trauma...
June 8, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28594752/residual-vitreous-cortex-at-the-fovea-during-vitrectomy-for-primary-rhegmatogenous-retinal-detachment-repair
#14
Eun Hyung Cho, Hee Chan Ku, Won Il, Eun Koo Lee
PURPOSE: To investigate the frequency of residual cortex and the effectiveness of removal of residual cortex in the fovea during vitrectomy for primary rhegmatogenous retinal detachment repair. METHODS: We retrospectively reviewed the charts and the operative videos of the 80 patients (80 eyes) who underwent vitrectomy for repair and who were observed for more than 6 months. After triamcinolone acetonide injection, we observed residual cortex on the surface of the retina...
June 7, 2017: Retina
https://www.readbyqxmd.com/read/28591286/structure-functional-correlation-using-adaptive-optics-oct-and-microperimetry-in-a-case-of-occult-macular-dystrophy
#15
Karlos Ítalo Viana, André Messias, Rubens Camargo Siqueira, Murilo W Rodrigues, Rodrigo Jorge
We report retinal functional and structural changes of a 40-year-old man diagnosed with occult macular dystrophy. Comprehensive ophthalmological evaluation was performed, followed by spectral-domain optical coherence tomography (SD-OC - Heidelberg) and image acquisition using an adaptive optics (AO) camera (RTX1, Imagine Eyes) for photoreceptor density analysis. Functional tests included full-field ERG (ERG) and multifocal electroretinography (mfERG) (Diagnosys, LLC) and microperimetry with scanning laser ophthalmoscope (SLO) fixation controlled (MAIA, CenterVUE)...
March 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28590963/acute-zonal-occult-outer-retinopathy-structural-and-functional-analysis-across-the-transition-zone-between-healthy-and-diseased-retina
#16
Tobias Duncker, Winston Lee, Fan Jiang, Rithambara Ramachandran, Donald C Hood, Stephen H Tsang, Janet R Sparrow, Vivienne C Greenstein
PURPOSE: To assess structure and function across the transition zone (TZ) between relatively healthy and diseased retina in acute zonal occult outer retinopathy. METHODS: Six patients (6 eyes; age 22-71 years) with acute zonal occult outer retinopathy were studied. Spectral-domain optical coherence tomography, fundus autofluorescence, near-infrared reflectance, color fundus photography, and fundus perimetry were performed and images were registered to each other...
January 23, 2017: Retina
https://www.readbyqxmd.com/read/28587935/human-antimicrobial-peptides-in-ocular-surface-defense
#17
REVIEW
Imran Mohammed, Dalia G Said, Harminder S Dua
Sight depends on the passage of light through the transparent cornea and being focused on the fovea. Its exposed position renders it vulnerable to microbial infection. The cornea has developed a wide array of defense mechanisms against infection, of which endogenous antimicrobial peptides (AMPs) are key. AMPs are essentially small molecular weight cationic peptides with a wide range of activity against virus, bacteria, fungi and parasites. Some proteins such as RNases and S100As are also included in this group...
June 3, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28579062/distribution-of-nonperfusion-area-on-ultra-widefield-fluorescein-angiography-in-eyes-with-diabetic-macular-edema-dave-study
#18
Wenying Fan, Kang Wang, Khalil Ghasemi Falavarjani, Min Sagong, Akihito Uji, Michael Ip, Charles C Wykoff, David M Brown, Jano van Hemert, SriniVas R Sadda
PURPOSE: To explore the distribution of nonperfusion area (NPA) in eyes with diabetic macular edema (DME) and its relationship with the severity of DME. DESIGN: Prospective, observational case series. METHODS: Forty eyes of 29 patients with treatment-naïve DME who participated in the DAVE study (NCT01552408) were included. Ultra-widefield fluorescein angiography images were sent to the Doheny Image Reading Center, where they were montaged and corrected using stereographic projection to adjust for peripheral distortion...
June 1, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28575309/nonhuman-primate-studies-to-advance-vision-science-and-prevent-blindness
#19
Michael J Mustari
Most primate behavior is dependent on high acuity vision. Optimal visual performance in primates depends heavily upon frontally placed eyes, retinal specializations, and binocular vision. To see an object clearly its image must be placed on or near the fovea of each eye. The oculomotor system is responsible for maintaining precise eye alignment during fixation and generating eye movements to track moving targets. The visual system of nonhuman primates has a similar anatomical organization and functional capability to that of humans...
May 31, 2017: ILAR Journal
https://www.readbyqxmd.com/read/28574945/a-series-of-five-patients-with-foveal-hypoplasia-demonstrating-good-visual-acuity
#20
Ian D Kirchner, Corey W Waldman, Janet S Sunness
BACKGROUND/PURPOSE: Foveal hypoplasia is associated with low vision in a variety of conditions. We report and show imaging studies for a series of five patients with foveal hypoplasia who had visual acuity ranging from 20/25 to 20/60. METHODS: Observational case series. PATIENTS: This series includes five patients aged 5 to 18 years who presented to the Greater Baltimore Medical Center, Hoover Low Vision Clinic. All patients showed a partial or complete absence of the fovea in both eyes on examination...
May 31, 2017: Retinal Cases & Brief Reports
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