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https://www.readbyqxmd.com/read/28318638/optical-coherence-tomography-guided-decisions-in-retinoblastoma-management
#1
Sameh E Soliman, Cynthia VandenHoven, Leslie D MacKeen, Elise Héon, Brenda L Gallie
PURPOSE: Assess the role of handheld optical coherence tomography (OCT) in guiding management decisions during diagnosis, treatment, and follow-up of eyes affected by retinoblastoma. DESIGN: Retrospective, noncomparative, single-institution case series. PARTICIPANTS: All children newly diagnosed with retinoblastoma from January 2011 to December 2015 who had an OCT session during their active treatment at The Hospital for Sick Children (SickKids) in Toronto, Canada...
March 15, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28315347/foveal-motion-standstill
#2
Derek H Arnold, Kirstie Petrie, Alan Johnston
Visual analyses of movement are disproportionately reliant on luminance contrast, as opposed to colour differences. One consequence is that if a moving pattern is defined solely by changes in colour (is equiluminant), people can report having no sensation of movement, despite still being able to 'see' the pattern. This is called motion standstill. To date there have been no formal reports of foveal motion standstill. Here we investigate whether this is because the conditions necessary for inducing motion standstill are particular to peripheral vision and therefore absent at the fovea...
March 14, 2017: Vision Research
https://www.readbyqxmd.com/read/28301857/structural-and-functional-characterization-of-benign-fleck-retina-using-multimodal-imaging
#3
Srividya Neriyanuri, Chetan Rao, Rajiv Raman
PURPOSE: To report structural and functional features in a case series of benign fleck retina using multimodal imaging. METHODS: Four cases with benign fleck retina underwent complete ophthalmic examination that included detailed history, visual acuity, and refractive error testing, FM-100 hue test, dilated fundus evaluation, full field electroretinogram, fundus photography with autofluorescence, fundus fluorescein angiography, and swept-source optical coherence tomography...
April 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28300548/new-insights-into-the-pathoanatomy-of-macular-holes-based-on-features-of-optical-coherence-tomography
#4
REVIEW
Hyewon Chung, Suk Ho Byeon
Various important findings related to the development and progression of idiopathic macular holes (MHs) have been described using optical coherence tomography (OCT) since Gass first described the stages of MH development using biomicroscopy in 1988 and 1995. We believe that a system for classifying and staging MHs should reflect the degree of disease status and its progression and have value not only from a practical point of view (by predicting the chance of closure or visual recovery) but also provides researchers and clinicians with insights into the pathogenesis and disease progression of MH...
March 11, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28293535/inflammatory-choroidal-neovascular-membrane-after-healed-tuberculous-choroidal-granuloma
#5
Sikander A K Lodhi, Khadija Saifuddin, Santhosh Devulapally
Objective: To present a case of choroidal granuloma masquerading as intraocular tumor that healed on anti-tuberculous treatment but led to the development of inflammatory choroidal neovascular membrane (CNVM). Method: A 42-year-old female patient with past history of hysterectomy presented with diminution of vision in the right eye. Fundus examination in the right eye showed a yellowish white choroidal mass with associated bullous retinal detachment superotemporal to fovea. Left eye fundus was normal. Fundus flourescein angiography showed early and late hyperflourescence with late pooling in serous detachments...
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28293534/near-infrared-fundus-autoflorescence-imaging-in-solar-retinopathy
#6
Maciej Czepita, Anna Machalińska, Damian Czepita
Solar retinopathy is a rare clinical entity caused by photochemical damage to the retinal pigment epithelium layer and photoreceptors of the fovea. Here we describe a case of a 33-year-old female patient diagnosed by near-infrared fundus autofluorescence imaging for signs of damage to the melanosomes of the retinal pigment epithelium of the fovea. The patient was advised to discontinue looking at the sun with the naked eye.
2017: GMS Ophthalmology Cases
https://www.readbyqxmd.com/read/28291203/-peripheral-refraction-cause-or-effect-of-refraction-development
#7
E P Tarutta, E N Iomdina, N G Kvaratskheliya, S V Milash, G V Kruzhkova
AIM: to study peripheral refraction and the shape of the eyeball in children with different clinical refraction. MATERIAL AND METHODS: Using an original method, peripheral refraction was measured at 10-12 degrees temporally and nasally from the fovea in 56 right eyes with different clinical, or axial, refraction of 20 boys and 36 girls aged 7 to 16 years (11.9±1.17 years on average). The shape of the eyeball was judged of by the ratio of its anterior-posterior axial length (AL) to horizontal diameter (HD)...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28288486/differential-disease-progression-in-atrophic-age-related-macular-degeneration-and-late-onset-stargardt-disease
#8
Moritz Lindner, Stanley Lambertus, Matthias M Mauschitz, Nathalie M Bax, Eveline Kersten, Anna Lüning, Jennifer Nadal, Steffen Schmitz-Valckenberg, Matthias Schmid, Frank G Holz, Carel B Hoyng, Monika Fleckenstein
Purpose: To compare the disease course of retinal pigment epithelium (RPE) atrophy secondary to age-related macula degeneratio (AMD) and late-onset Stargardt disease (STGD1). Methods: Patients were examined longitudinally by fundus autofluorescence, near-infrared reflectance imaging, and best-corrected visual acuity (BCVA). Areas of RPE atrophy were quantified using semi-automated software, and the status of the fovea was evaluated based on autofluorescence and near-infrared reflectance images...
February 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28286000/a-novel-interception-strategy-in-a-miniature-robber-fly-with-extreme-visual-acuity
#9
Trevor J Wardill, Samuel T Fabian, Ann C Pettigrew, Doekele G Stavenga, Karin Nordström, Paloma T Gonzalez-Bellido
Our visual system allows us to rapidly identify and intercept a moving object. When this object is far away, we base the trajectory on the target's location relative to an external frame of reference [1]. This process forms the basis for the constant bearing angle (CBA) model, a reactive strategy that ensures interception since the bearing angle, formed between the line joining pursuer and target (called the range vector) and an external reference line, is held constant [2-4]. The CBA model may be a fundamental and widespread strategy, as it is also known to explain the interception trajectories of bats and fish [5, 6]...
March 20, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28283280/foveal-hypoplasia-in-patients-with-stickler-syndrome
#10
Itsuka Matsushita, Tatsuo Nagata, Takaaki Hayashi, Kenichi Kimoto, Toshiaki Kubota, Masahito Ohji, Shunji Kusaka, Hiroyuki Kondo
PURPOSE: To determine the microstructure of the fovea in patients with Stickler syndrome using imaging by spectral-domain optical coherence tomography (SD OCT) and swept-source OCT. DESIGN: Retrospective case series study. PARTICIPANTS: A total of 39 eyes of 25 patients with genetically confirmed Stickler syndrome were studied. METHODS: All of the patients had mutations in the COL2A1 gene and were diagnosed with Stickler syndrome...
March 7, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28282697/-initial-clinical-experiences-using-ocriplasmin-for-the-treatment-of-vitreomacular-traction-with-or-without-a-macular-hole
#11
J Lenk, E Matthé, S Ventzke, L E Pillunat, D Sandner
Purpose In vitreomacular traction (VMT), there is abnormal adhesion between the vitreous cortex and the retina, especially in the fovea. Symptoms of VMT include metamorphopsia and a decrease in visual acuity. Since 2013, ocriplasmin (Jetrea®) has been approved for treatment of symptomatic vitreomacular traction with or without macular holes (≤ 400 µm). Methods We retrospectively examined twenty-three eyes of twenty-one patients who underwent intravitreal ocriplasmin treatment for symptomatic vitreomacular traction with or without macular holes...
March 10, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28282060/visual-dysfunction-and-its-correlation-with-retinal-changes-in-patients-with-alzheimer-s-disease
#12
V Polo, M J Rodrigo, E Garcia-Martin, S Otin, J M Larrosa, M I Fuertes, M P Bambo, L E Pablo, M Satue
AimTo evaluate visual dysfunction and its correlation with structural changes in the retina in patients with Alzheimer's disease (AD).MethodsPatients with AD (n=24) and controls (n=24) underwent evaluation of visual acuity (VA), color vision (using the Farnsworth and L'Anthony desaturated (D) 15 color tests), and contrast sensitivity vision (CSV; using the Pelli-Robson chart and CSV-1000E test) to measure visual dysfunction. Structural measurements of the retinal nerve fiber layer (RNFL) and macular thickness were obtained using spectral domain-optical coherence tomography (SD-OCT)...
March 10, 2017: Eye
https://www.readbyqxmd.com/read/28280989/the-role-of-pigment-epithelial-detachment-in-amd-with-submacular-hemorrhage-treated-with-vitrectomy-and-subretinal-co-application-of-rtpa-and-anti-vegf
#13
F Treumer, S Wienand, K Purtskhvanidze, J Roider, J Hillenkamp
PURPOSE: To assess the incidence of pigment epithelial detachment (PED) in age-related macular degeneration (AMD) with submacular hemorrhage (SMH) and its response to treatment with pars plana vitrectomy (ppV), subretinal co-application of recombinant tissue plasminogen activator (rtPA) and anti-VEGF, and an intravitreal gas tamponade. METHODS: Consecutive interventional case series of 132 eyes of 129 patients with neovascular AMD with SMH. All eyes underwent ppV with subretinal co-application of rtPA and bevacizumab followed by a gas tamponade...
March 9, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28277878/effect-of-smoking-on-the-thickness-of-retinal-layers-in-healthy-smokers
#14
Rahmi Duman, Reşat Duman, Mehmet Cem Sabaner, Ersan Çetinkaya
PURPOSE: To compare the thicknesses of the retinal layers in smokers with those of non smoking healthy subjects using spectral-domain optical coherence tomography (SD-OCT). METHODS: One hundred and eight subjects were included in the study. Two groups were separated as smokers and non-smokers. Both groups were chosen to be similar in terms of age and gender. SD-OCT images were generated with Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany). An automated algorithm was developed to segment the macular retina into eight layers and quantitate the thickness of each layer for the fovea, parafovea and perifovea...
March 3, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28272284/quantitative-analysis-of-structural-alterations-in-the-choroid-of-patients-with-active-beh%C3%A3-et-uveitis
#15
Sumru Onal, Gunay Uludag, Merih Oray, Emre Mengi, Carl P Herbort, Mehmet Akman, Mustafa M Metin, Aylin Koc Akbay, Ilknur Tugal-Tutkun
PURPOSE: To quantitatively analyze in vivo morphology of subfoveal choroid during an acute attack of Behçet uveitis. METHODS: In this prospective study, 28 patients with Behçet uveitis of ≤4-year duration, and 28 control subjects underwent enhanced depth imaging optical coherence tomography. A novel custom software was used to calculate choroidal stroma-to-choroidal vessel lumen ratio. Subfoveal choroidal thickness was measured at fovea and 750 μm nasal, temporal, superior, and inferior to fovea...
March 7, 2017: Retina
https://www.readbyqxmd.com/read/28272283/dexamethasone-intravitreal-implant-vs-ranibizumab-in-the-treatment-of-macular-edema-secondary-to-brachytherapy-for-choroidal-melanoma
#16
Andrea Russo, Michele Reibaldi, Teresio Avitabile, Maurizio G Uva, Livio Marco Franco, Caterina Gagliano, Vincenza Bonfiglio, Corrado Spatola, Giuseppe Privitera, Antonio Longo
PURPOSE: To evaluate the efficacy of an intravitreal dexamethasone (Dex) implant 0.7 mg compared with intravitreal ranibizumab (Ra) for the treatment of radiation maculopathy with macular edema secondary to plaque brachytherapy in choroidal melanoma. METHODS: Eight patients were treated with intravitreal Ra, and eight patients received the Dex intravitreal implant. Visual acuity and foveal thickness were evaluated using spectral domain optical coherence tomography...
March 7, 2017: Retina
https://www.readbyqxmd.com/read/28272255/choroidal-area-assessment-in-various-fundus-sectors-of-patients-at-different-stages-of-primary-open-angle-glaucoma-by-using-enhanced-depth-imaging-optical-coherence-tomography
#17
Mu Li, Xiao-Qin Yan, Yin-Wei Song, Jing-Min Guo, Hong Zhang
To compare the choroidal area in different eye fundus sectors of subjects with normal eyes, early-stage primary open-angle glaucoma (POAG) eyes, and 10° tubular visual field POAG eyes using enhanced depth imaging optical coherence tomography.Twenty-five normal, 25 early-stage POAG, and 25 ten-degree tubular visual field POAG eyes were recruited. Enhanced depth imaging optical coherence tomography was used to measure the choroidal area in different fundus sectors (fovea; 10° superior, inferior, temporal, and 24° superior, inferior, temporal, nasal to the fovea) and the peripapillary sector...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28265755/the-effect-of-center-point-shift-on-the-measurement-of-macular-thickness-a-spectral-domain-optical-coherence-tomography-study
#18
Kyoung Nam Kim, Il Hwan Shin, Jae Yun Sung, Baek Soo Kwak, Hyung Bin Lim, Young Joon Jo, Jung Yeul Kim
PURPOSE: To evaluate the effect of spectral domain-optical coherence tomography (SD-OCT) measurement center shift on the measurement of macular thickness. METHODS: This was a prospective observational case series. A total of 60 normal eyes of 60 subjects included in the study. SD-OCT macular scanning (macular cube 512 × 128 scan) was performed twice by an experienced examiner. The average retinal thicknesses of the nine macular sectors as defined by the Early Treatment Diabetic Retinopathy Study (ETDRS) were recorded...
March 6, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28260189/behavioral-pieces-of-neuroethological-puzzles
#19
Kenneth C Catania
In this review, I give a first-person account of surprising insights that have come from the behavioral dimension of neuroethological studies in my laboratory. These studies include the early attempts to understand the function of the nose in star-nosed moles and to explore its representation in the neocortex. This led to the discovery of a somatosensory fovea that parallels the visual fovea of primates in several ways. Subsequent experiments to investigate the assumed superiority of star-nosed moles to their relatives when locating food led to the unexpected discovery of stereo olfaction in common moles...
March 4, 2017: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
https://www.readbyqxmd.com/read/28257458/high-speed-adaptive-optics-line-scan-confocal-retinal-imaging-for-human-eye
#20
Jing Lu, Boyu Gu, Xiaolin Wang, Yuhua Zhang
PURPOSE: Continuous and rapid eye movement causes significant intraframe distortion in adaptive optics high resolution retinal imaging. To minimize this artifact, we developed a high speed adaptive optics line scan confocal retinal imaging system. METHODS: A high speed line camera was employed to acquire retinal image and custom adaptive optics was developed to compensate the wave aberration of the human eye's optics. The spatial resolution and signal to noise ratio were assessed in model eye and in living human eye...
2017: PloS One
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