keyword
https://read.qxmd.com/read/38634855/tools-and-methods-for-high-throughput-single-cell-imaging-with-the-mother-machine
#21
JOURNAL ARTICLE
Ryan Thiermann, Michael Sandler, Gursharan Ahir, John T Sauls, Jeremy Schroeder, Steven Brown, Guillaume Le Treut, Fangwei Si, Dongyang Li, Jue D Wang, Suckjoon Jun
Despite much progress, image processing remains a significant bottleneck for high-throughput analysis of microscopy data. One popular platform for single-cell time-lapse imaging is the mother machine, which enables long-term tracking of microbial cells under precisely controlled growth conditions. While several mother machine image analysis pipelines have been developed in the past several years, adoption by a non-expert audience remains a challenge. To fill this gap, we implemented our own software, MM3, as a plugin for the multidimensional image viewer napari...
April 18, 2024: ELife
https://read.qxmd.com/read/38634232/a-palliative-care-goals-model-for-people-with-dementia-and-their-family-consensus-achieved-in-an-international-delphi-study
#22
JOURNAL ARTICLE
Mayumi Nishimura, Karen Harrison Dening, Elizabeth L Sampson, Edison Iglesias de Oliveira Vidal, Miharu Nakanishi, Nathan Davies, Wilson Abreu, Sharon Kaasalainen, Yvonne Eisenmann, Laura Dempsey, Kirsten J Moore, Sascha R Bolt, Judith Mm Meijers, Natashe Lemos Dekker, Mitsunori Miyashita, Takeo Nakayama, Jenny T van der Steen
BACKGROUND: Advance care planning in dementia includes supporting the person and their family to consider important goals of care. International research reports the importance of psycho-social-spiritual aspects towards end of life. AIM: To develop a multidimensional international palliative care goals model in dementia for use in practice. DESIGN: International Delphi study integrating consensus and evidence from a meta-qualitative study...
April 2024: Palliative Medicine
https://read.qxmd.com/read/38632913/integrating-health-nutrition-and-environmental-impacts-of-foods-a-life-cycle-impact-assessment-and-modelling-analysis-of-foods-in-canada
#23
JOURNAL ARTICLE
Sarah Jarvis, Michalis Hadjikakou, Jason Wu, Michael Classens, Laura Chiavaroli, John Sievenpiper, Mary L'Abbe, David Jenkins, Vasanti Malik
BACKGROUND: Given the urgency of transitioning towards sustainable nutrition, dietary shifts that provide co-benefits to human health and the environment are imperative. There is currently no database of the environmental impacts of foods that reflects Canada's unique geographical and agri-climatic context and regional inputs and emissions. To determine sustainable diets, harmonising nutritional considerations with environmental impacts is also essential for an equitable comparison of foods...
April 2024: Lancet. Planetary Health
https://read.qxmd.com/read/38632143/identification-of-early-warning-signals-of-infectious-diseases-in-hospitals-by-integrating-clinical-treatment-and-disease-prevention
#24
JOURNAL ARTICLE
Lei Zhang, Min-Ye Li, Chen Zhi, Min Zhu, Hui Ma
The global incidence of infectious diseases has increased in recent years, posing a significant threat to human health. Hospitals typically serve as frontline institutions for detecting infectious diseases. However, accurately identifying warning signals of infectious diseases in a timely manner, especially emerging infectious diseases, can be challenging. Consequently, there is a pressing need to integrate treatment and disease prevention data to conduct comprehensive analyses aimed at preventing and controlling infectious diseases within hospitals...
April 18, 2024: Current Medical Science
https://read.qxmd.com/read/38630018/vibronic-coupling-drives-the-ultrafast-internal-conversion-in-a-functionalized-free-base-porphyrin
#25
JOURNAL ARTICLE
Vasilis Petropoulos, Pavel S Rukin, Frank Quintela, Mattia Russo, Luca Moretti, Ana Moore, Thomas Moore, Devens Gust, Deborah Prezzi, Gregory D Scholes, Elisa Molinari, Giulio Cerullo, Filippo Troiani, Carlo A Rozzi, Margherita Maiuri
Internal conversion (IC) is a common radiationless transition in polyatomic molecules. Theory predicts that molecular vibrations assist IC between excited states, and ultrafast experiments can provide insight into their structure-function relationship. Here we elucidate the dynamics of the vibrational modes driving the IC process within the Q band of a functionalized porphyrin molecule. Through a combination of ultrafast multidimensional spectroscopies and theoretical modeling, we observe a 60 fs Q y -Q x IC and demonstrate that it is driven by the interplay among multiple high-frequency modes...
April 17, 2024: Journal of Physical Chemistry Letters
https://read.qxmd.com/read/38628822/social-support-health-behaviors-self-esteem-and-successful-aging-in-a-sub-saharan-african-sample-of-older-adults-test-of-a-sequential-mediation-model
#26
JOURNAL ARTICLE
Chima Charles Igbokwe, Blessing Nneka Ome, Runcie C W Chidebe, Beatrice Chinwe Igbokwe, Mary Basil Nwoke, Chidiebere Wisdom Obioha, Benard Chibuike Okechi, JohnBosco Chika Chukwuorji
BACKGROUND AND OBJECTIVES: Previous research demonstrates that social support facilitates successful aging across all cultures. However, the factors that potentially mediate the link between social support and successful aging remain unclear. This study examined whether a healthy lifestyle and self-esteem mediate the association between social support and successful aging. It was hypothesized that the relationship between social support (family, friends, and significant other) and successful aging would be serially mediated by both healthy lifestyle and self-esteem...
2024: Innovation in Aging
https://read.qxmd.com/read/38627325/co-occurring-dominance-and-ideal-point-processes-a-general-irtree-framework-for-multidimensional-item-responding
#27
JOURNAL ARTICLE
Viola Merhof, Thorsten Meiser
Responding to rating scale items is a multidimensional process, since not only the substantive trait being measured but also additional personal characteristics can affect the respondents' category choices. A flexible model class for analyzing such multidimensional responses are IRTree models, in which rating responses are decomposed into a sequence of sub-decisions. Different response processes can be involved in item responding both sequentially across those sub-decisions and as co-occurring processes within sub-decisions...
April 16, 2024: Behavior Research Methods
https://read.qxmd.com/read/38626600/a-parental-burnout-modelling-based-on-perfectionism-mediated-through-self-compassion-in-parents-of-students-suffering-from-specific-learning-behavioral-disorder
#28
JOURNAL ARTICLE
Hamid Jafarian Yasar, Zabihullah Pirani, Zeinab Ein Ali
The association between parental burnout and perfectionism, and whether and to what extent it is mediated by self-compassion, in case of mothers of children with Specific Learning Disorder (SLD) were rarely investigated in the related literature. To fill the gap felt, the present study aimed at providing a model for self-compassion, parental burnout, and perfectionism. The participants were 305 mothers of children with SLD, from Hamedan province, Iran, who had been referred to the relevant treatment centers between 2020 and 2021...
April 15, 2024: Acta Psychologica
https://read.qxmd.com/read/38626087/social-support-distress-stress-anxiety-and-depression-as-predictors-of-suicidal-thoughts-among-selected-university-students-in-bangladesh
#29
JOURNAL ARTICLE
Sihab Howlader, Sumaiya Abedin, Md Mosfequr Rahman
This study examines the association of perceived social support with suicidal thoughts among a young adult sample of university students and estimates the degree to which perceived stress, distress, anxiety, and depression may explain the association. A cross-sectional survey was conducted from June to September 2022 among 642 students, selected using the probability proportional to size procedure, at a large university in Bangladesh. We used the Multidimensional Scale of Perceived Social Support (MSPSS) to measure support...
2024: PLOS Glob Public Health
https://read.qxmd.com/read/38625428/piloting-rasch-model-scoring-of-the-national-eye-institute-visual-function-questionnaire-in-uveitis
#30
JOURNAL ARTICLE
Lisa Gittel, Jeany Q Li, Jennifer Dell, Maximilian W M Wintergerst, Carsten Heinz, Robert P Finger, Jan Henrik Terheyden
INTRODUCTION: The National Eye Institute Visual Function Questionnaire (NEI VFQ) is a common patient-reported outcome measure (PROM) in uveitis trials. Its psychometric properties using state-of-the-art scoring based on Rasch models, a latent trait model that improves accuracy of PROMs assessment, has not yet been investigated. METHODS: The study participants were recruited online from uveitis patient organizations, where individuals self-reported their uveitis diagnosis and visual acuity level...
April 16, 2024: Journal of Ophthalmic Inflammation and Infection
https://read.qxmd.com/read/38624178/flexible-tactile-sensors-for-3d-force-detection
#31
JOURNAL ARTICLE
Chengcheng Han, Zhi Cao, Yiran Hu, Zhiwei Zhang, Chengyu Li, Zhong Lin Wang, Zhiyi Wu
As tactile force sensing has become increasingly significant in the field of machine haptics, achieving multidimensional force sensing remains a challenge. We propose a 3D flexible force sensor that consists of an axisymmetric hemispherical protrusion and four equally sized quarter-circle electrodes. By simulating the device using a force and electrical field model, it has been found that the magnitude and direction of the force can be expressed through the voltage relationship of the four electrodes when the magnitude of the shear force remains constant and its direction varies within 0-360°...
April 16, 2024: Nano Letters
https://read.qxmd.com/read/38615492/examining-domains-of-psychological-flexibility-and-inflexibility-as-treatment-mechanisms-in-acceptance-and-commitment-therapy-a-comprehensive-systematic-and-meta-analytic-review
#32
REVIEW
Jenna A Macri, Ronald D Rogge
The current systematic and meta-analytic review sought to integrate a growing number of studies examining dimensions of psychological flexibility as treatment mechanisms for Acceptance and Commitment Therapy (ACT). Analyses of 77 records (67 unique studies; Ntotal  = 9123 participants) from comprehensive searches of multiple databases suggested that ACT interventions led to reduced inflexibility (i.e., lowered global inflexibility, lack of present moment awareness, cognitive fusion, experiential avoidance, self-as-content, & inaction) and increased flexibility (i...
April 10, 2024: Clinical Psychology Review
https://read.qxmd.com/read/38613093/persistent-food-insecurity-and-material-hardships-a-latent-class-analysis-of-experiences-among-venezuelan-refugees-and-migrants-in-urban-colombia
#33
JOURNAL ARTICLE
Andrea L Wirtz, Megan Stevenson, José Rafael Guillén, Jennifer Ortiz, Miguel Ángel Barriga Talero, Kathleen R Page, Jhon Jairo López, Jhon Fredy Ramirez Correa, Damary Martínez Porras, Ricardo Luque Núñez, Julián Alfredo Fernández-Niño, Paul B Spiegel
The causes and conditions of displacement often increase the vulnerability of migrant and refugee populations to food insecurity, alongside other material hardships. We aimed to examine the multidimensional aspects and patterns of food insecurity and other material hardships in a cross-sectional sample of 6221 Venezuelan refugees and migrants in urban Colombia using a latent class analysis. Using multinomial and logistic regression models, we investigated the demographic and migratory experiences associated with identified classes and how class membership is associated with multiple health outcomes among Venezuelan refugees and migrants, respectively...
April 4, 2024: Nutrients
https://read.qxmd.com/read/38611594/a-multimodal-transformer-model-for-recognition-of-images-from-complex-laparoscopic-surgical-videos
#34
JOURNAL ARTICLE
Rahib H Abiyev, Mohamad Ziad Altabel, Manal Darwish, Abdulkader Helwan
The determination of the potential role and advantages of artificial intelligence-based models in the field of surgery remains uncertain. This research marks an initial stride towards creating a multimodal model, inspired by the Video-Audio-Text Transformer, that aims to reduce negative occurrences and enhance patient safety. The model employs text and image embedding state-of-the-art models (ViT and BERT) to assess their efficacy in extracting the hidden and distinct features from the surgery video frames...
March 23, 2024: Diagnostics
https://read.qxmd.com/read/38609776/somatic-symptom-distress-is-not-related-to-cardioceptive-accuracy
#35
JOURNAL ARTICLE
Tara M Petzke, Ferenc Köteles, Anna Pohl, Michael Witthöft
OBJECTIVE: (Cardiac) interoception was long considered a key mechanism behind symptom perception in persistent somatic symptoms (PSS). In this study, we aimed to extend earlier findings to clarify this potential interoceptive mechanisms of PSS. METHODS: A cross-sectional sample of 251 participants (23.1% with self-reported functional somatic syndrome) completed a laboratory study with two cardioceptive accuracy tasks (Schandry task and a new cardiac signal detection task) and multiple questionnaires...
April 7, 2024: Journal of Psychosomatic Research
https://read.qxmd.com/read/38607977/a-novel-electronic-health-record-based-machine-learning-model-to-predict-severe-hypoglycemia-leading-to-hospitalizations-in-older-adults-with-diabetes-a-territory-wide-cohort-and-modeling-study
#36
JOURNAL ARTICLE
Mai Shi, Aimin Yang, Eric S H Lau, Andrea O Y Luk, Ronald C W Ma, Alice P S Kong, Raymond S M Wong, Jones C M Chan, Juliana C N Chan, Elaine Chow
BACKGROUND: Older adults with diabetes are at high risk of severe hypoglycemia (SH). Many machine-learning (ML) models predict short-term hypoglycemia are not specific for older adults and show poor precision-recall. We aimed to develop a multidimensional, electronic health record (EHR)-based ML model to predict one-year risk of SH requiring hospitalization in older adults with diabetes. METHODS AND FINDINGS: We adopted a case-control design for a retrospective territory-wide cohort of 1,456,618 records from 364,863 unique older adults (age ≥65 years) with diabetes and at least 1 Hong Kong Hospital Authority attendance from 2013 to 2018...
April 2024: PLoS Medicine
https://read.qxmd.com/read/38607930/linking-fine-root-lifespan-to-root-chemical-and-morphological-traits-a-global-analysis
#37
JOURNAL ARTICLE
Jiawen Hou, M Luke McCormack, Peter B Reich, Tao Sun, Richard P Phillips, Hans Lambers, Han Y H Chen, Yiyang Ding, Louise H Comas, Oscar J Valverde-Barrantes, Emily F Solly, Gregoire T Freschet
Fine root lifespan is a critical trait associated with contrasting root strategies of resource acquisition and protection. Yet, its position within the multidimensional "root economics space" synthesizing global root economics strategies is largely uncertain, and it is rarely represented in frameworks integrating plant trait variations. Here, we compiled the most comprehensive dataset of absorptive median root lifespan (MRL) data including 98 observations from 79 woody species using (mini-)rhizotrons across 40 sites and linked MRL to other plant traits to address questions of the regulators of MRL at large spatial scales...
April 16, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38604935/psychometric-properties-of-the-eating-attitudes-test-26-in-spanish-schoolchildren
#38
JOURNAL ARTICLE
Néstor Montoro-Pérez, Raimunda Montejano-Lozoya, David Martín-Baena, Marta Talavera-Ortega, M Rosario Gómez-Romero
INTRODUCTION: Disordered Eating Attitudes and Behaviours (DEABs) can impact both the mental and physical health of children. Early detection is crucial to prevent complications and improve outcomes. The Eating Attitudes Test-26 (EAT-26) is a widely used, cost-effective tool for assessing DEABs. OBJECTIVE: To evaluate the psychometric properties of the EAT-26 by analysing its factor structure, internal consistency, convergent validity, and measurement invariance across sexes in Spanish schoolchildren...
April 10, 2024: Anales de pediatría
https://read.qxmd.com/read/38604382/the-relation-between-questionnaire-measured-self-reported-emotional-eating-and-disordered-eating-behaviors-a-meta-analysis-of-nearly-three-decades-of-research
#39
REVIEW
Wesley R Barnhart, Maria Kalantzis, Christina Gaggiano, Abby L Braden
Extensive research exists on the association between self-reported emotional eating (EE) and disordered eating (DE) behaviors. Heterogeneity exists by type (e.g., unidimensional vs. multidimensional) and valence (e.g., negative vs. positive) of self-reported EE, and no previous meta-analyses have examined the association between self-reported EE and DE behaviors. A total of 67 studies (N = 26,289; 43 reporting relations across one model, and 24 reporting relations across more than one model) met inclusion criteria; ranges for age and publication date were 18...
April 9, 2024: Appetite
https://read.qxmd.com/read/38603718/kco-balancing-class-distribution-in-just-in-time-software-defect-prediction-using-kernel-crossover-oversampling
#40
JOURNAL ARTICLE
Ahmad Muhaimin Ismail, Siti Hafizah Ab Hamid, Asmiza Abdul Sani, Nur Nasuha Mohd Daud
The performance of the defect prediction model by using balanced and imbalanced datasets makes a big impact on the discovery of future defects. Current resampling techniques only address the imbalanced datasets without taking into consideration redundancy and noise inherent to the imbalanced datasets. To address the imbalance issue, we propose Kernel Crossover Oversampling (KCO), an oversampling technique based on kernel analysis and crossover interpolation. Specifically, the proposed technique aims to generate balanced datasets by increasing data diversity in order to reduce redundancy and noise...
2024: PloS One
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