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https://www.readbyqxmd.com/read/29148740/effect-of-an-imposed-contact-on-secondary-structure-in-the-denatured-state-of-yeast-iso-1-cytochome-c
#1
Travis A Danielson, Jessica M Stine, Tanveer A Dar, Klara Briknarova, Bruce E Bowler
There is considerable evidence that long-range interactions stabilize residual protein structure under denaturing conditions. However, evaluation of the effect of a specific contact on structure in the denatured state has been difficult. Iso-1-cytochrome c variants with a Lys54-->His mutation form a particularly stable His-heme loop in the denatured state, suggestive of loop-induced residual structure. We have used multidimensional NMR methods to assign (1)H and (15)N backbone amide and (13)C backbone and side chain chemical shifts in the denatured state of iso-1-cytochrome c carrying the Lys54-->His mutation in 3 and 6 M guanidine hydrochloride and at both pH 6...
November 17, 2017: Biochemistry
https://www.readbyqxmd.com/read/29147119/psychosocial-factors-predicting-length-of-hospitalization-in-elderly-individuals-with-diabetes-in-selected-hospitals-of-isfahan-university-of-medical-sciences-isfahan-iran-in-2015
#2
Omeleila Baharlooei, Mousa Alavi, Marzieh Adelmehraban
BACKGROUND: Currently, researchers seek to identify factors related to length of hospital stay in elderly in order to reduce burden on the health system. The importance of either physiological or psychological factors in determining health outcomes has been well stablished; however, the possible contribution of psychosocial factors particularly in elderly patients with diabetes is also of special importance. This study aimed to know what psychosocial variables predicts length of hospital stay in elderly patients with diabetes...
May 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/29143630/examining-the-mechanisms-by-which-women-s-status-and-empowerment-affect-skilled-birth-attendant-use-in-senegal-a-structural-equation-modeling-approach
#3
Kyoko Shimamoto, Jessica D Gipson
BACKGROUND: Despite the reduction in maternal deaths globally, maternal mortality rates remain unacceptably high, particularly in some regions of the world. In sub-Saharan Africa, maternal mortality rates have even increased recently, with 201,000 deaths in 2015 as compared to 179,000 in 2013. Use of a skilled birth attendant (SBA) at delivery has remained low, despite evidence of the effectiveness of SBAs in reducing maternal deaths. Women's empowerment is increasingly recognized as a key determinant of maternal health care-seeking and outcomes, yet empirical examinations of the linkages between women's empowerment and delivery care use are particularly limited, especially from sub-Saharan Africa...
November 8, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29135230/multidimensional-spectral-fingerprints-of-a-new-family-of-coherent-analytical-spectroscopies
#4
Nathan Andrew Neff-Mallon, John C Wright
Triply Resonant Sum Frequency (TRSF) and Doubly Vibrationally Enhanced (DOVE) spectroscopies are examples of a recently developed family of Coherent Multidimensional Spectroscopies (CMDS) that are analogous to current analytical spectroscopies. They are based on creating quantum mechanical superposition states that are fully coherent and lack intermediate quantum state populations that cause quenching or other relaxation effects. They provide multidimensional spectral fingerprints consisting of mixtures of vibrational and electronic states...
November 14, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29133283/open-source-electronic-health-record-systems-for-low-resource-settings-systematic-review
#5
REVIEW
Assel Syzdykova, André Malta, Maria Zolfo, Ermias Diro, José Luis Oliveira
BACKGROUND: Despite the great impact of information and communication technologies on clinical practice and on the quality of health services, this trend has been almost exclusive to developed countries, whereas countries with poor resources suffer from many economic and social issues that have hindered the real benefits of electronic health (eHealth) tools. As a component of eHealth systems, electronic health records (EHRs) play a fundamental role in patient management and effective medical care services...
November 13, 2017: JMIR Medical Informatics
https://www.readbyqxmd.com/read/29132719/a-multidimensional-comparison-between-modis-and-viirs-aod-in-estimating-ground-level-pm2-5-concentrations-over-a-heavily-polluted-region-in-china
#6
Fei Yao, Menglin Si, Weifeng Li, Jiansheng Wu
Satellite-derived aerosol optical depth (AOD) has been proven effective for estimating ground-level particles with an aerodynamic diameter <2.5μm (PM2.5) concentrations. Using a time fixed effects regression model, we compared the capacity of two AOD sources, Moderate Resolution Imaging Spectroradiometer (MODIS) and Visible Infrared Imaging Radiometer Suite (VIIRS), to estimate ground-level PM2.5 concentrations over a heavily polluted region in China. Regarding high-quality AOD data, the results show that the VIIRS model performs better than the MODIS model with respect to all model accuracy evaluation indexes (e...
November 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29130059/inter-and-intra-individual-variation-in-emotional-complexity-methodological-considerations-and-theoretical-implications
#7
Anthony D Ong, Alex J Zautra, Patrick H Finan
The degree of relationship between positive and negative emotional states or emotional complexity is a topic of ongoing methodological and theoretical debate. At issue is whether positive and negative emotions are opposite ends of a bipolar continuum or independent dimensions in a bivariate distribution with little degree of overlap. In this review, we summarize a body of work suggesting that the distinction between positive and negative emotions varies both between and within individuals over time as a function of cognition and changes in informational demands, a perspective called the Dynamic Model of Affect (DMA)...
June 2017: Current Opinion in Behavioral Sciences
https://www.readbyqxmd.com/read/29128740/motivational-capacities-after-prolonged-interpersonal-childhood-trauma-in-institutional-settings-in-a-sample-of-austrian-adult-survivors
#8
Dina Weindl, Matthias Knefel, Tobias M Glück, Ulrich S Tran, Brigitte Lueger-Schuster
A considerable amount of research has been conducted on the aversive impact of prolonged interpersonal childhood trauma, but data on possible associations with motivational concepts (self-efficacy, self-esteem and locus of control) in adult survivors is scarce. The purpose of this study is to investigate specific coherences between childhood abuse and adult life events with (a) motivational concepts (MC), (b) the emotion regulation strategy "goal-directed behavior" and (c) the possible mediation of emotion regulation (ER) on motivational concepts...
November 9, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29125876/psychometric-properties-of-the-resilience-scale-for-adults-rsa-and-its-relationship-with-life-stress-anxiety-and-depression-in-a-hispanic-latin-american-community-sample
#9
Roxanna Morote, Odin Hjemdal, Patricia Martinez Uribe, Jozef Corveleyn
Resilience is a multi-dimensional construct associated with health and well-being. At present, we do not yet have a valid, scientific instrument that is designed to evaluate adult resilience in Spanish-speaking countries and that accounts for family, social and individual components. This study aimed at investigating the construct and cross-cultural validity of the Resilience Scale for Adults (RSA) by combining Confirmatory Factor Analysis (CFA), Multidimensional Scaling (MDS) and Hierarchical Regression models in a Hispanic Latin-American group...
2017: PloS One
https://www.readbyqxmd.com/read/29125631/the-convergence-and-divergence-of-impulsivity-facets-in-daily-life
#10
Sarah H Sperry, Donald P Lynam, Thomas R Kwapil
OBJECTIVES: Impulsivity appears to be best conceptualized as a multidimensional construct. For example, the UPPS-P model posits that there are five underlying facets of impulsivity. The present study examined the expression of the UPPS-P facets in daily life using experience sampling methodology (ESM). A specific goal of the study was to examine positive urgency, a facet added to the original UPPS model, and its convergence and divergence from the negative urgency facet. METHODS: A large non-clinical sample of young adults (n=294) completed the UPPS-P scale and were signaled to complete questionnaires assessing daily affect, cognitions, sense of self, and impulsive behaviors eight times a day for seven days in their daily life...
November 10, 2017: Journal of Personality
https://www.readbyqxmd.com/read/29121913/predicting-health-related-quality-of-life-in-cancer-patients-receiving-chemotherapy-a-structural-equation-approach-using-the-self-control-model
#11
Yu-Ri Park, Eun-Young Park, Jung-Hee Kim
BACKGROUND: According to the self-control model, self-control works as a protective factor and a psychological resource. Although an understanding of the effect(s) of peripheral neuropathy on quality of life is important to healthcare professionals, previous studies do not facilitate broad comprehension in this regard. The purpose of this cross-sectional study was to test the multidimensional assumptions of quality of life of patients with cancer, with focus on their self-control. METHODS: A structural equation model was tested on patients with cancer at the oncology clinic of a university hospital where patients received chemotherapy...
November 9, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29117870/is-there-enough-interest-in-and-pleasure-in-the-concept-of-depression-the-development-of-the-leuven-affect-and-pleasure-scale-laps
#12
Koen Demyttenaere, Philippe Mortier, Glenn Kiekens, Ronny Bruffaerts
OBJECTIVE: Presence of negative mood (depressed mood) and anhedonia (lack of interest and pleasure) are considered core symptoms of depression, while absence of positive mood is not taken into account. It is therefore remarkable that the depression scales routinely used to assess changes during antidepressant treatment (Hamilton Depression Rating Scale [HDRS], Montgomery-Åsberg Depression Rating Scale [MADRS]) do not really take into account anhedonia. Several scales were developed to assess positive mood and hedonic tone, but they only partially cover the multidimensional concept...
November 9, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/29116645/the-impact-of-physical-activity-on-fatigue-and-quality-of-life-during-and-after-adjuvant-treatment-for-breast-cancer
#13
Florian Manneville, Christine Rotonda, Thierry Conroy, Franck Bonnetain, Francis Guillemin, Abdou Y Omorou
BACKGROUND: Although physical activity (PA) can alleviate fatigue and improve quality of life (QoL) in patients with breast cancer (BC), not all domains of PA may have equal impact. The objective of the current study was to examine the longitudinal impact of PA components on the evolution of fatigue and QoL during and after adjuvant treatment for BC. METHODS: The women included in the study were participants in the 2-year longitudinal FATSEIN ("Fatigue dans le cancer du Sein") study...
November 8, 2017: Cancer
https://www.readbyqxmd.com/read/29112719/a-lesion-model-of-envy-and-schadenfreude-legal-deservingness-and-moral-dimensions-as-revealed-by-neurodegeneration
#14
Hernando Santamaría-García, Sandra Baez, Pablo Reyes, José A Santamaría-García, José M Santacruz-Escudero, Diana Matallana, Analía Arévalo, Mariano Sigman, Adolfo M García, Agustín Ibáñez
The study of moral emotions (i.e. Schadenfreude and envy) is critical to understand the ecological complexity of everyday interactions between cognitive, affective, and social cognition processes. Most previous studies in this area have used correlational imaging techniques and framed Schadenfreude and envy as unified and monolithic emotional domains. Here, we profit from a relevant neurodegeneration model to disentangle the brain regions engaged in three dimensions of Schadenfreude and envy: deservingness, morality, and legality...
November 2, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29112705/coloured-petri-nets-for-multilevel-multiscale-and-multidimensional-modelling-of-biological-systems
#15
Fei Liu, Monika Heiner, David Gilbert
Owing to the availability of data of one biological phenomenon at different levels/scales, modelling of biological systems is moving from single level/scale to multiple levels/scales, which introduces a number of challenges. Coloured Petri nets (ColPNs) have been successfully applied to multilevel, multiscale and multidimensional modelling of some biological systems, addressing many of these challenges. In this article, we first review the basics of ColPNs and some popular extensions, and then their applications for multilevel, multiscale and multidimensional modelling of biological systems...
November 3, 2017: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/29111532/deciphering-composition-and-connectivity-of-a-natural-product-with-the-assistance-of-ms-and-2d-nmr
#16
Anastasiya I Vinokur, Paul B White, Maurice Tagatsing Fotsing, Charmaine Arderne, Derek Tantoh Ndinteh, Martha M Vestling, Ilia A Guzei
A complementary application of three analytical techniques, viz. multidimensional nuclear magnetic resonance spectroscopy (NMR), mass spectrometry (MS), and single-crystal X-ray diffractometry was required to identify and refine two natural products isolated from Millettia versicolor and solvent of crystallization. The two compounds, namely 3-(2H-1,3-benzodioxol-5-yl)-6-methoxy-8,8-dimethyl-4H,8H-pyrano[2,3-h]chromen-4-one, or durmillone, (I), and (2E)-1-(4-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-2-hydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one, (II), could not be separated by routine column chromatography and cocrystallized in a 2:1 ratio with 0...
November 1, 2017: Acta Crystallographica. Section C, Structural Chemistry
https://www.readbyqxmd.com/read/29107967/embedding-graphs-in-lorentzian-spacetime
#17
James R Clough, Tim S Evans
Geometric approaches to network analysis combine simply defined models with great descriptive power. In this work we provide a method for embedding directed acyclic graphs (DAG) into Minkowski spacetime using Multidimensional scaling (MDS). First we generalise the classical MDS algorithm, defined only for metrics with a Riemannian signature, to manifolds of any metric signature. We then use this general method to develop an algorithm which exploits the causal structure of a DAG to assign space and time coordinates in a Minkowski spacetime to each vertex...
2017: PloS One
https://www.readbyqxmd.com/read/29106280/the-nature-and-correlates-of-the-dark-triad-the-answers-depend-on-the-questions
#18
Ashley L Watts, Irwin D Waldman, Sarah Francis Smith, Holly E Poore, Scott O Lilienfeld
The past several decades have witnessed a proliferation of research on the dark triad (DT), a set of traits comprising Machiavellianism, narcissism, and psychopathy. The bulk of DT research has been marked by several core assumptions, most notably that each DT construct is a monolithic entity that is clearly separable from its counterpart DT constructs. To examine the tenability of these assumptions, we pooled data from 2 samples of North American community members (ns = 312 and 351) to explore (a) the external validity and profile similarities of DT indicators and (b) the factor structure of the DT...
October 2017: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/29104326/parents-adjustment-following-the-death-of-their-child-resilience-is-multidimensional-and-differs-across-outcomes-examined
#19
Frank J Infurna, Suniya S Luthar
We examine whether the previously reported commonness of resilience to significant adversity extends to parents' death of a child. To examine our research questions, we apply growth mixture models to longitudinal data from 461 parents in the HILDA study who had experienced child loss. The proportion of parents manifesting resilience were 44%, 56%, 21%, 32%, and 16% for life satisfaction, negative affect, positive affect, general health, and physical functioning, respectively. Only 5% were resilient across all five indices, whereas 28% did not show a resilient trajectory across all outcomes...
June 2017: Journal of Research in Personality
https://www.readbyqxmd.com/read/29103676/the-validity-and-clinical-utility-of-the-disabilities-of-the-arm-shoulder-and-hand-questionnaire-for-hand-injuries-in-developing-country-contexts-a-systematic-review
#20
Susan de Klerk, Helen Buchanan, Christina Jerosch-Herold
STUDY DESIGN: Systematic review. INTRODUCTION: The Disabilities of the Arm Shoulder and Hand Questionnaire has multiple language versions from many countries around the world. In addition there is extensive research evidence of its psychometric properties. PURPOSE OF THE STUDY: The purpose of this study was to systematically review the evidence available on the validity and clinical utility of the Disabilities of the Arm Shoulder and Hand as a measure of activity and participation in patients with musculoskeletal hand injuries in developing country contexts...
November 2, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
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