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https://www.readbyqxmd.com/read/27913156/the-oral-spelling-profile-of-posterior-cortical-atrophy-and-the-nature-of-the-graphemic-representation
#1
Silvia Primativo, Keir X X Yong, Timothy J Shakespeare, Sebastian J Crutch
Spelling is a complex cognitive task where central and peripheral components are involved in engaging resources from many different cognitive processes. The present paper aims to both characterize the oral spelling deficit in a population of patients affected by a neurodegenerative condition and to clarify the nature of the graphemic representation within the currently available spelling models. Indeed, the nature of graphemic representation as a linear or multi-componential structure is still debated. Different hypotheses have been raised about its nature in the orthographic lexicon, with one positing that graphemes are complex objects whereby quantity and identity are separately represented in orthographic representations and can thus be selectively impaired...
November 29, 2016: Neuropsychologia
https://www.readbyqxmd.com/read/27911797/meeting-the-sustainable-development-goals-leads-to-lower-world-population-growth
#2
Guy J Abel, Bilal Barakat, Samir Kc, Wolfgang Lutz
Here we show the extent to which the expected world population growth could be lowered by successfully implementing the recently agreed-upon Sustainable Development Goals (SDGs). The SDGs include specific quantitative targets on mortality, reproductive health, and education for all girls by 2030, measures that will directly and indirectly affect future demographic trends. Based on a multidimensional model of population dynamics that stratifies national populations by age, sex, and level of education with educational fertility and mortality differentials, we translate these goals into SDG population scenarios, resulting in population sizes between 8...
November 29, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27906499/individual-differences-in-human-brain-development
#3
REVIEW
Timothy T Brown
This article discusses recent scientific advances in the study of individual differences in human brain development. Focusing on structural neuroimaging measures of brain morphology and tissue properties, two kinds of variability are related and explored: differences across individuals of the same age and differences across age as a result of development. A recent multidimensional modeling study is explained, which was able to use brain measures to predict an individual's chronological age within about one year on average, in children, adolescents, and young adults between 3 and 20 years old...
December 1, 2016: Wiley Interdisciplinary Reviews. Cognitive Science
https://www.readbyqxmd.com/read/27895470/validity-of-the-control-preferences-scale-in-patients-with-emotional-disorders
#4
Carlos De Las Cuevas, Wenceslao Peñate
BACKGROUND: The Control Preferences Scale (CPS) is the most frequently used measure of patients' preferred roles in treatment decisions. The aim of this study was to provide data about the validity of CPS in psychiatric care of patients with emotional disorders. METHODS: The original CPS was translated to Spanish using the process of cross-cultural adaptation of self-reported measures as the methodological model for Spanish translation. The final version was tested in a convenience sample of 621 consecutive psychiatric outpatients (461 depressive and 160 anxiety disorders) that also completed the Shared Decision-Making Questionnaire, the Multidimensional Health Locus of Control Scale, the Drug Attitude Inventory, and a questionnaire including sociodemographic and clinical variables...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27894258/multidimensional-construct-of-life-satisfaction-in-older-adults-in-korea-a-six-year-follow-up-study
#5
Hyun Ja Lim, Dae Kee Min, Lilian Thorpe, Chel Hee Lee
BACKGROUND: Aging raises wide-ranging issues within social, economic, welfare, and health care systems. Life satisfaction (LS) is regarded as an indicator of quality of life which, in turn, is associated with mortality and morbidity in older adults. The objective of this study was to identify the relevant predictors of life satisfaction and to investigate changes in a multidimensional construct of LS over time. METHODS: This analysis utilized data from the large-scale, nationally representative Korean Retirement and Income Study (KReIS), a longitudinal survey conducted biennially from 2005 to 2011...
November 28, 2016: BMC Geriatrics
https://www.readbyqxmd.com/read/27894014/a-fast-approach-to-3d-hsqc-based-spectroscopy-based-on-a-fourier-phase-encoding-of-pre-targeted-resonances
#6
Yulan Lin, Pieter E S Smith, Zhiyong Zhang, Lucio Frydman
Multidimensional Nuclear Magnetic Resonance (NMR) provides a unique window into structure and dynamics at an atomic level. Traditionally, given the scan-by-scan time modulation involved in these experiments, the duration of nD NMR increases exponentially with spectral dimensionality. In addition, acquisition times increase as the number of spectral elements being sought in each indirect domain - given by the ratio between the spectral bandwidth being targeted and the resolution desired. These long sampling times can be substantially reduced by exploiting information that is often available from lower-dimensionality acquisitions...
November 21, 2016: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/27893798/diversity-and-impacts-of-mining-on-the-non-volant-small-mammal-communities-of-two-vegetation-types-in-the-brazilian-amazon
#7
Natália Carneiro Ardente, Átilla Colombo Ferreguetti, Donald Gettinger, Pricila Leal, Ana Cristina Mendes-Oliveira, Fernanda Martins-Hatano, Helena Godoy Bergallo
The Carajás National Forest contains some of the largest iron ore deposits in the world. The majority of the minerals are found below a plant community known as Savana Metalófila, or "Canga", which represents only 3% of the landscape within the Carajás National Forest (CNF). The aim of our study was to understand the diversity of community of non-volant small mammals in the two predominant vegetation types: Ombrophilous Forest and Canga, and to examine how mining impacts these communities. Sampling was conducted from January 2010 to August 2011 in 11 sampling sites divided by the total area of Canga and 12 sampling sites in the forest, totalizing 23 sites...
2016: PloS One
https://www.readbyqxmd.com/read/27889453/simultaneous-real-time-imaging-of-leading-and-lagging-strand-synthesis-reveals-the-coordination-dynamics-of-single-replisomes
#8
Karl E Duderstadt, Hylkje J Geertsema, Sarah A Stratmann, Christiaan M Punter, Arkadiusz W Kulczyk, Charles C Richardson, Antoine M van Oijen
The molecular machinery responsible for DNA replication, the replisome, must efficiently coordinate DNA unwinding with priming and synthesis to complete duplication of both strands. Due to the anti-parallel nature of DNA, the leading strand is copied continuously, while the lagging strand is produced by repeated cycles of priming, DNA looping, and Okazaki-fragment synthesis. Here, we report a multidimensional single-molecule approach to visualize this coordination in the bacteriophage T7 replisome by simultaneously monitoring the kinetics of loop growth and leading-strand synthesis...
November 15, 2016: Molecular Cell
https://www.readbyqxmd.com/read/27885478/the-roland-morris-disability-questionnaire-one-or-more-dimensions
#9
Tiê Parma Yamato, Chris G Maher, Bruno T Saragiotto, Mark J Catley, James H McAuley
PURPOSE: The Roland-Morris Disability Questionnaire (RMDQ) is one of the most recommended questionnaires to assess disability. Some previous studies support the assumption that the RMDQ is a unidimensional measure; however, recent studies have suggested that this measure has more than one domain and should be considered as a multidimensional scale. Therefore, the aim of this study was to analyse the structure of the RMDQ in a large sample of patients with low back pain using two different statistical approaches...
November 24, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27878226/psychometric-properties-of-multidimensional-health-locus-of-control-a-and-general-self-efficacy-scale-in-civil-servants-elsa-brasil-musculoskeletal-study-elsa-brasil-msk
#10
Luciana A C Machado, Rosa W Telles, Luciana Costa-Silva, Sandhi M Barreto
Background: Health-related control and self-efficacy beliefs can be assessed in the general population using Multidimensional Health Locus of Control-A subscales (MHLC-A) and the General Self-Efficacy Scale (GSES), respectively. Objective: To test construct validity, internal consistency, reliability (test-retest) and ceiling and floor effects of Portuguese-Brazil versions of MHLC-A and GSES. Method: Civil servants (N=2901) enrolled in a large Brazilian cohort were included...
June 30, 2016: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/27875183/gaussian-cubes-real-time-modeling-for-visual-exploration-of-large-multidimensional-datasets
#11
Zhe Wang, Nivan Ferreira, Youhao Wei, Aarthy Sankari Bhaskar, Carlos Scheidegger
Recently proposed techniques have finally made it possible for analysts to interactively explore very large datasets in real time. However powerful, the class of analyses these systems enable is somewhat limited: specifically, one can only quickly obtain plots such as histograms and heatmaps. In this paper, we contribute Gaussian Cubes, which significantly improves on state-of-the-art systems by providing interactive modeling capabilities, which include but are not limited to linear least squares and principal components analysis (PCA)...
January 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/27875141/visual-interaction-with-dimensionality-reduction-a-structured-literature-analysis
#12
Dominik Sacha, Leishi Zhang, Michael Sedlmair, John A Lee, Jaakko Peltonen, Daniel Weiskopf, Stephen C North, Daniel A Keim
Dimensionality Reduction (DR) is a core building block in visualizing multidimensional data. For DR techniques to be useful in exploratory data analysis, they need to be adapted to human needs and domain-specific problems, ideally, interactively, and on-the-fly. Many visual analytics systems have already demonstrated the benefits of tightly integrating DR with interactive visualizations. Nevertheless, a general, structured understanding of this integration is missing. To address this, we systematically studied the visual analytics and visualization literature to investigate how analysts interact with automatic DR techniques...
January 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/27873543/hearing-aid-fitting-and-fine-tuning-based-on-estimated-individual-traits
#13
Christoph Völker, Stephan M A Ernst, Birger Kollmeier
OBJECTIVE: A generalised concept for hearing aid fitting and fine-tuning based on estimated individual traits is presented along first implementations in this report. DESIGN: To estimate the individual traits, a set of auditory model-based performance measures is used to generate promising candidates within the algorithm's parameter space for a subsequent subjective rating. For the subjective assessment, a fast and intuitive multi-stimulus test denoted as combined discrimination and classification (CoDiCl) is presented to capture user preferences for an optimised setting...
November 22, 2016: International Journal of Audiology
https://www.readbyqxmd.com/read/27872348/resolving-dimensionality-problems-with-whoqol-bref-item-responses
#14
Harsha N Perera, Zahra Izadikhah, Peter O'Connor, Peter McIlveen
The World Health Organization Quality of Life Scale (WHOQOL-BREF) is predicated on a multidimensional perspective on quality of life (QOL); yet studies are unclear about the latent structure underlying responses. This article reports on a study conducted to investigate the structure of WHOQOL-BREF scores. Competing latent structures of the data were examined in a general population sample. In addition, the complete factorial invariance of the retained model was investigated across gender. We also investigated latent mean differences in the QOL dimensions over age as well as age by gender interactions effects...
November 20, 2016: Assessment
https://www.readbyqxmd.com/read/27872347/toward-an-empirical-multidimensional-structure-of-anhedonia-reward-sensitivity-and-positive-emotionality-an-exploratory-factor-analytic-study
#15
Thomas M Olino, Dana L McMakin, Erika E Forbes
Positive emotionality, anhedonia, and reward sensitivity share motivational and experiential elements of approach motivation and pleasure. Earlier work has examined the interrelationships among these constructs from measures of extraversion. More recently, the Research Domain Criteria introduced the Positive Valence Systems as a primary dimension to better understand psychopathology. However, the suggested measures tapping this construct have not yet been integrated within the structural framework of personality, even at the level of self-report...
November 20, 2016: Assessment
https://www.readbyqxmd.com/read/27872180/on-learning-natural-science-categories-that-violate-the-family-resemblance-principle
#16
Robert M Nosofsky, Craig A Sanders, Alex Gerdom, Bruce J Douglas, Mark A McDaniel
The general view in psychological science is that natural categories obey a coherent, family-resemblance principle. In this investigation, we documented an example of an important exception to this principle: Results of a multidimensional-scaling study of igneous, metamorphic, and sedimentary rocks (Experiment 1) suggested that the structure of these categories is disorganized and dispersed. This finding motivated us to explore what might be the optimal procedures for teaching dispersed categories, a goal that is likely critical to science education in general...
November 21, 2016: Psychological Science
https://www.readbyqxmd.com/read/27871320/assessment-of-the-dimensionality-of-the-wijma-delivery-expectancy-experience-questionnaire-using-factor-analysis-and-rasch-analysis
#17
J F Pallant, H M Haines, P Green, J Toohill, J Gamble, D K Creedy, J Fenwick
BACKGROUND: Fear of childbirth has negative consequences for a woman's physical and emotional wellbeing. The most commonly used measurement tool for childbirth fear is the Wijma Delivery Expectancy Questionnaire (WDEQ-A). Although originally conceptualized as unidimensional, subsequent investigations have suggested it is multidimensional. This study aimed to undertake a detailed psychometric assessment of the WDEQ-A; exploring the dimensionality and identifying possible subscales that may have clinical and research utility...
November 21, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27869508/risk-factors-and-mediators-of-suicidal-ideation-among-korean-adolescents
#18
Yi Jin Kim, Sung Seek Moon, Jang Hyun Lee, Joon Kyung Kim
BACKGROUND: A significant number of Korean adolescents have suicidal ideations and it is more prevalent among adolescents than any other age group in Korea. AIMS: This study was conducted to attain a better understanding of the contributing factors to suicidal ideation among Korean adolescents. METHOD: We recruited 569 high school students in Grades 10 and 11 in Pyeongtaek, Korea. The Beck Scale for Suicidal Ideation was used to measure suicidal ideation as the outcome variable...
November 21, 2016: Crisis
https://www.readbyqxmd.com/read/27868215/the-contribution-of-clinical-and-psychosocial-factors-to-fatigue-in-182-patients-with-inflammatory-bowel-disease-a-cross-sectional-study
#19
M Artom, W Czuber-Dochan, J Sturt, T Murrells, C Norton
BACKGROUND: Fatigue is a frequently reported and predominant symptom experienced by patients with inflammatory bowel disease (IBD) and its impact has been associated with poorer quality of life (QoL). The complex interplay between disease-related variables and potentially modifiable psychosocial factors in IBD-fatigue has yet to be unravelled. AIM: To evaluate the contribution of clinical, sociodemographic and psychosocial factors to the severity and impact of IBD-fatigue and QoL...
November 20, 2016: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27866890/genome-sequence-of-a-5-310-year-old-maize-cob-provides-insights-into-the-early-stages-of-maize-domestication
#20
Jazmín Ramos-Madrigal, Bruce D Smith, J Víctor Moreno-Mayar, Shyam Gopalakrishnan, Jeffrey Ross-Ibarra, M Thomas P Gilbert, Nathan Wales
The complex evolutionary history of maize (Zea mays L. ssp. mays) has been clarified with genomic-level data from modern landraces and wild teosinte grasses [1, 2], augmenting archaeological findings that suggest domestication occurred between 10,000 and 6,250 years ago in southern Mexico [3, 4]. Maize rapidly evolved under human selection, leading to conspicuous phenotypic transformations, as well as adaptations to varied environments [5]. Still, many questions about the domestication process remain unanswered because modern specimens do not represent the full range of past diversity due to abandonment of unproductive lineages, genetic drift, on-going natural selection, and recent breeding activity...
November 11, 2016: Current Biology: CB
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