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https://www.readbyqxmd.com/read/29792092/the-relationship-between-narcissism-and-personality-traits-of-the-five-factor-model-in-adolescents-and-young-adults
#1
Marc Allroggen, Peter Rehmann, Eva Schürch, Carolyn C Morf, Michael Kölch
Introduction: Narcissism is seen as a multidimensional construct that consists of two manifestations: grandiose and vulnerable narcissism. In order to define these two manifestations, their relationship to personality factors has increasingly become of interest. However, so far no studies have considered the relationship between different phenotypes of narcissism and personality factors in adolescents. Method: In a cross-sectional study, we examine a group of adolescents (n = 98; average age 16...
May 24, 2018: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
https://www.readbyqxmd.com/read/29787425/a-metabolomic-serum-signature-from-nonhuman-primates-treated-with-a-radiation-countermeasure-gamma-tocotrienol-and-exposed-to-ionizing-radiation
#2
Evan L Pannkuk, Evagelia C Laiakis, Albert J Fornace, Oluseyi O Fatanmi, Vijay K Singh
The search for and development of radiation countermeasures to treat acute lethal radiation injury has been underway for the past six decades, resulting in the identification of multiple classes of radiation countermeasures. However, to date only granulocyte colony-stimulating factor (Neupogen) and PEGylated granulocyte colony-stimulating factor (Neulasta) have been approved by the U.S. Food and Drug Administration for the treatment of hematopoietic acute radiation syndrome. Gamma-tocotrienol has demonstrated radioprotective efficacy in murine and nonhuman primate models...
July 2018: Health Physics
https://www.readbyqxmd.com/read/29785860/the-development-and-psychometric-properties-of-the-multidimensional-assessment-of-teamwork-in-sport
#3
Desmond McEwan, Bruno D Zumbo, Mark A Eys, Mark R Beauchamp
The purpose of this research was to develop a questionnaire to assess the multidimensional construct of teamwork in sport and to examine various aspects of validity related to that instrument. A preliminary questionnaire was first created, and feedback on this instrument was then obtained from a sample of team-sport athletes (n = 30) and experts in sport psychology (n = 8). A modified version of the questionnaire was then completed by 607 athletes from 48 teams, and 5 multilevel confirmatory factor analyses were conducted to examine the structural properties of data derived from this instrument...
May 22, 2018: Journal of Sport & Exercise Psychology
https://www.readbyqxmd.com/read/29785691/psychometric-properties-of-the-multidimensional-loss-scale-with-refugee-women-at-risk-recently-arrived-in-australia
#4
Lyn Vromans, Robert D Schweitzer, Mark Brough, Ignacio Correa-Velez, Kate Murray, Caroline Lenette
Refugee women-at-risk represent a distinct and vulnerable refugee population. We investigated the psychometric properties of the Multidimensional Loss Scale (MLS) with 104 women-at-risk, recently-arrived in Australia. Cross-sectional survey included: the MLS (indexing loss events and loss distress); Harvard Trauma Questionnaire (Indexing Trauma Events and Trauma Symptoms), and; Hopkins Symptom Checklist-37 (indexing anxiety, depression, and somatization symptoms). Exploratory factor analyses of MLS loss distress revealed a six-factor model (loss of symbolic self; loss of home; loss of interdependence; loss of past aspirations; interpersonal loss, and; loss of intrapersonal integrity)...
May 21, 2018: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/29782582/surfaces-from-the-visual-past-recovering-high-resolution-terrain-data-from-historic-aerial-imagery-for-multitemporal-landscape-analysis
#5
Christopher Sevara, Geert Verhoeven, Michael Doneus, Erich Draganits
Historic aerial images are invaluable sources of aid to archaeological research. Often collected with large-format photogrammetric quality cameras, these images are potential archives of multidimensional data that can be used to recover information about historic landscapes that have been lost to modern development. However, a lack of camera information for many historic images coupled with physical degradation of their media has often made it difficult to compute geometrically rigorous 3D content from such imagery...
2018: Journal of archaeological method and theory
https://www.readbyqxmd.com/read/29780976/modeling-individual-cyclic-variation-in-human-behavior
#6
Emma Pierson, Tim Althoff, Jure Leskovec
Cycles are fundamental to human health and behavior. Examples include mood cycles, circadian rhythms, and the menstrual cycle. However, modeling cycles in time series data is challenging because in most cases the cycles are not labeled or directly observed and need to be inferred from multidimensional measurements taken over time. Here, we present Cyclic Hidden Markov Models (CyH-MMs) for detecting and modeling cycles in a collection of multidimensional heterogeneous time series data. In contrast to previous cycle modeling methods, CyHMMs deal with a number of challenges encountered in modeling real-world cycles: they can model multivariate data with both discrete and continuous dimensions; they explicitly model and are robust to missing data; and they can share information across individuals to accommodate variation both within and between individual time series...
April 2018: Proceedings of the International World-Wide Web Conference
https://www.readbyqxmd.com/read/29779058/genetics-of-resistant-hypertension-the-missing-heritability-and-opportunities
#7
REVIEW
Samantha K Teixeira, Alexandre C Pereira, Jose E Krieger
PURPOSE OF THE REVIEW: Blood pressure regulation in humans has long been known to be a genetically determined trait. The identification of causal genetic modulators for this trait has been unfulfilling at the least. Despite the recent advances of genome-wide genetic studies, loci associated with hypertension or blood pressure still explain a very low percentage of the overall variation of blood pressure in the general population. This has precluded the translation of discoveries in the genetics of human hypertension to clinical use...
May 19, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29772912/relations-between-empathy-and-anxiety-dimensions-in-inpatient-adolescents
#8
Malgorzata Gambin, Carla Sharp
BACKGROUND AND OBJECTIVES: A better understanding of the relationships between empathy and internalizing disorders is needed to plan therapeutic interventions for children and adolescents. Several studies have revealed positive relations of internalizing symptoms to personal distress and affective empathy. However, there is a lack of studies that take into account the multidimensional nature of anxiety in its relation to empathy. DESIGN: Structural equation modeling was used to test the moderated mediation model of the relations between empathy, depression and anxiety dimensions and the moderating role of gender on these associations in inpatient adolescents...
May 17, 2018: Anxiety, Stress, and Coping
https://www.readbyqxmd.com/read/29772277/severity-therapeutic-and-activity-tear-biomarkers-in-dry-eye-disease-a-clinical-trial-sub-analysis
#9
José Pinto-Fraga, Amalia Enríquez-de-Salamanca, Margarita Calonge, María J González-García, Alberto López-Miguel, Alberto López-de la Rosa, Carmen García-Vázquez, Virginia Calder, Michael E Stern, Itziar Fernández
PURPOSE: To evaluate the effect of 0.1%-fluorometholone (FML) on tear inflammatory molecule levels after 22-days treatment in dry eye disease (DED) patients exposed to an adverse controlled environment (ACE), identifying different biomarkers. METHODS: Sub-analysis of a double-masked randomized clinical trial. Forty-one DED patients received 4-drops daily of topical FML (FML-group) or polyvinyl-alcohol (PA-group) for 22 days. At day 21, patients were exposed to an ACE...
May 14, 2018: Ocular Surface
https://www.readbyqxmd.com/read/29771881/-prediction-of-activity-and-severity-of-endocrine-ophthalmopathy-by-multidimensional-linear-regression-modeling
#10
V G Lihvantseva, M S Afanasev, E A Rudenko, A V Karaulov, S S Afanasev, E V Korosteleva, V A Vygodin
Endocrine ophthalmopathy (EOP) is a severe chronic autoimmune disease associated with autoimmune thyroid pathology that leads to loss of sight, cosmetic defects and quality of life decrease. EOP is difficult to give prognosis for due to various factors affecting its course and outcome. PURPOSE: To develop a reliable and precise prognosis method for EOP activity and severity based on personalized combination of risk factors in specific patients by multidimensional linear regression modeling...
2018: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29769073/measuring-bothersome-menopausal-symptoms-development-and-validation-of-the-menoscores-questionnaire
#11
Kamma Sundgaard Lund, Volkert Dirk Siersma, Karl Bang Christensen, Frans Boch Waldorff, John Brodersen
BACKGROUND: The experience of menopausal symptoms is common and an adequate patient-reported outcome measure is crucial in studies where women are treated for these symptoms. The aims of this study were to identify a patient-reported outcome measure for bothersome menopausal symptoms and, in the absence of an adequate tool, to develop a new measure with high content validity, and to validate it using modern psychometric methods. METHODS: The literature was reviewed for existing questionnaires and checklists for bothersome menopausal symptoms...
May 16, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29766490/emotional-hyper-reactivity-and-cardiometabolic-risk-in-remitted-bipolar-patients-a-machine-learning-approach
#12
A A Dargél, F Roussel, S Volant, B Etain, R Grant, J-M Azorin, K M'Bailara, F Bellivier, T Bougerol, J-P Kahn, P Roux, V Aubin, P Courtet, M Leboyer, F Kapczinski, C Henry
OBJECTIVE: Remitted bipolar disorder (BD) patients frequently present with chronic mood instability and emotional hyper-reactivity, associated with poor psychosocial functioning and low-grade inflammation. We investigated emotional hyper-reactivity as a dimension for characterization of remitted BD patients, and clinical and biological factors for identifying those with and without emotional hyper-reactivity. METHOD: A total of 635 adult remitted BD patients, evaluated in the French Network of Bipolar Expert Centers from 2010-2015, were assessed for emotional reactivity using the Multidimensional Assessment of Thymic States...
May 15, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29763741/bayesian-estimation-of-multidimensional-latent-variables-and-its-asymptotic-accuracy
#13
Keisuke Yamazaki
Hierarchical learning models, such as mixture models and Bayesian networks, are widely employed for unsupervised learning tasks, such as clustering analysis. They consist of observable and latent variables, which represent the given data and their underlying generation process, respectively. It has been pointed out that conventional statistical analysis is not applicable to these models, because redundancy of the latent variable produces singularities in the parameter space. In recent years, a method based on algebraic geometry has allowed us to analyze the accuracy of predicting observable variables when using Bayesian estimation...
March 13, 2018: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29761450/mathematical-modeling-approaches-in-plant-metabolomics
#14
Lisa Fürtauer, Jakob Weiszmann, Wolfram Weckwerth, Thomas Nägele
The experimental analysis of a plant metabolome typically results in a comprehensive and multidimensional data set. To interpret metabolomics data in the context of biochemical regulation and environmental fluctuation, various approaches of mathematical modeling have been developed and have proven useful. In this chapter, a general introduction to mathematical modeling is presented and discussed in context of plant metabolism. A particular focus is laid on the suitability of mathematical approaches to functionally integrate plant metabolomics data in a metabolic network and combine it with other biochemical or physiological parameters...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29760689/-trichoderma-biofertilizer-links-to-altered-soil-chemistry-altered-microbial-communities-and-improved-grassland-biomass
#15
Fengge Zhang, Yunqian Huo, Adam B Cobb, Gongwen Luo, Jiqiong Zhou, Gaowen Yang, Gail W T Wilson, Yingjun Zhang
In grasslands, forage and livestock production results in soil nutrient deficits as grasslands typically receive no nutrient inputs, leading to a loss of grassland biomass. The application of mature compost has been shown to effectively increase grassland nutrient availability. However, research on fertilization regime influence and potential microbial ecological regulation mechanisms are rarely conducted in grassland soil. We conducted a two-year experiment in meadow steppe grasslands, focusing on above- and belowground consequences of organic or Trichoderma biofertilizer applications and potential soil microbial ecological mechanisms underlying soil chemistry and microbial community responses...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29760543/microbiota-modification-by-probiotic-supplementation-reduces-colitis-associated-colon-cancer-in-mice
#16
Maria Carolina S Mendes, Daiane Sm Paulino, Sandra R Brambilla, Juliana A Camargo, Gabriela F Persinoti, José Barreto C Carvalheira
AIM: To investigate the effect of probiotic supplementation during the development of an experimental model of colitis associated colon cancer (CAC). METHODS: C57BL/6 mice received an intraperitoneal injection of azoxymethane (10 mg/kg), followed by three cycles of sodium dextran sulphate diluted in water (5% w/v). Probiotic group received daily a mixture of Lactobacillus acidophilus , Lactobacillus rhamnosus and Bifidobacterium bifidum . Microbiota composition was assessed by 16S rRNA Illumina HiSeq sequencing...
May 14, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29760065/temperature-regulates-nf-%C3%AE%C2%BAb-dynamics-and-function-through-timing-of-a20-transcription
#17
C V Harper, D J Woodcock, C Lam, M Garcia-Albornoz, A Adamson, L Ashall, W Rowe, P Downton, L Schmidt, S West, D G Spiller, D A Rand, M R H White
NF-κB signaling plays a pivotal role in control of the inflammatory response. We investigated how the dynamics and function of NF-κB were affected by temperature within the mammalian physiological range (34 °C to 40 °C). An increase in temperature led to an increase in NF-κB nuclear/cytoplasmic oscillation frequency following Tumor Necrosis Factor alpha (TNFα) stimulation. Mathematical modeling suggested that this temperature sensitivity might be due to an A20-dependent mechanism, and A20 silencing removed the sensitivity to increased temperature...
May 14, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29759232/synthesis-identification-integration-one-pot-hydrothermal-preparation-of-fluorescent-nitrogen-doped-carbon-nanodots-for-differentiating-nucleobases-with-the-aid-of-multivariate-chemometrics-analysis
#18
Qianfen Zhuang, Wei Cao, Yongnian Ni, Yong Wang
Most of the conventional multidimensional differential sensors currently need at least two-step fabrication, namely synthesis of probe(s) and identification of multiple analytes by mixing of analytes with probe(s), and were conducted using multiple sensing elements or several devices. In the study, we chose five different nucleobases (adenine, cytosine, guanine, thymine, and uracil) as model analytes, and found that under hydrothermal conditions, sodium citrate could react directly with various nucleobases to yield different nitrogen-doped carbon nanodots (CDs)...
August 1, 2018: Talanta
https://www.readbyqxmd.com/read/29758021/testing-the-psychometric-properties-of-the-environmental-attitudes-inventory-on-undergraduate-students-in-the-arab-context-a-test-retest-approach
#19
Entesar Ali AlMenhali, Khalizani Khalid, Shilpa Iyanna
The Environmental Attitudes Inventory (EAI) was developed to evaluate the multidimensional nature of environmental attitudes; however, it is based on a dataset from outside the Arab context. This study reinvestigated the construct validity of the EAI with a new dataset and confirmed the feasibility of applying it in the Arab context. One hundred and forty-eight subjects in Study 1 and 130 in Study 2 provided valid responses. An exploratory factor analysis (EFA) was used to extract a new factor structure in Study 1, and confirmatory factor analysis (CFA) was performed in Study 2...
2018: PloS One
https://www.readbyqxmd.com/read/29755507/computational-protein-phenotype-characterization-of-il10ra-mutations-causative-to-early-onset-inflammatory-bowel-disease-ibd
#20
Fahad A Al-Abbasi, Kaleemuddin Mohammed, Saida Sadath, Babajan Banaganapalli, Khalidah Nasser, Noor A Shaik
The deleterious amino acid substitution mutations in IL-10 receptor alpha gene are most frequently reported in several autoimmune diseases including early onset-inflammatory bowel disease (IBD). Despite the important role of IL-10 RA in maintaining immune homeostasis, the specific structural and functional implications of these mutations on protein phenotype, stability, ligand binding and post translational characteristics is not well explored. Therefore, this study performed the multidimensional computational analysis of IL10RA missense variations causative to pediatric or early onset inflammatory bowel disease (<5 years of age)...
2018: Frontiers in Genetics
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