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https://www.readbyqxmd.com/read/29341344/the-medial-temporal-lobe-functional-connectivity-patterns-associated-with-forming-different-mental-representations
#1
Signy Sheldon, Brian Levine
The medial temporal lobes (MTL), and more specifically the hippocampus, are critical for forming mental representations of past experiences - autobiographical memories - and for forming other 'non-experienced' types of mental representations, such as imagined scenarios. How the MTL coordinate with other brain areas to create these different types of representations is not well understood. To address this issue, we performed a task-based functional connectivity analysis on a previously published dataset in which fMRI data were collected as participants created different types of mental representations under three conditions...
January 17, 2018: Hippocampus
https://www.readbyqxmd.com/read/29341071/anticholinergic-medication-for-antipsychotic-induced-tardive-dyskinesia
#2
REVIEW
Hanna Bergman, Karla Soares-Weiser
BACKGROUND: Antipsychotic (neuroleptic) medication is used extensively to treat people with serious mental illnesses. However, it is associated with a wide range of adverse effects, including movement disorders. Because of this, many people treated with antipsychotic medication also receive anticholinergic drugs in order to reduce some of the associated movement side-effects. However, there is also a suggestion from animal experiments that the chronic administration of anticholinergics could cause tardive dyskinesia...
January 17, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29341067/vitamin-e-for-antipsychotic-induced-tardive-dyskinesia
#3
REVIEW
Karla Soares-Weiser, Nicola Maayan, Hanna Bergman
BACKGROUND: Antipsychotic (neuroleptic) medication is used extensively to treat people with chronic mental illnesses. Its use, however, is associated with adverse effects, including movement disorders such as tardive dyskinesia (TD) - a problem often seen as repetitive involuntary movements around the mouth and face. Vitamin E has been proposed as a treatment to prevent or decrease TD. OBJECTIVES: The primary objective was to determine the clinical effects of vitamin E in people with schizophrenia or other chronic mental illness who had developed antipsychotic-induced TD...
January 17, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29339310/distant-from-input-evidence-of-regions-within-the-default-mode-network-supporting-perceptually-decoupled-and-conceptually-guided-cognition
#4
Charlotte Murphy, Elizabeth Jefferies, Shirley-Ann Rueschemeyer, Mladen Sormaz, Hao-Ting Wang, Daniel S Margulies, Jonathan Smallwood
The default mode network supports a variety of mental operations such as semantic processing, episodic memory retrieval, mental time travel and mind-wandering, yet the commonalities between these functions remains unclear. One possibility is that this system supports cognition that is independent of the immediate environment; alternatively or additionally, it might support higher-order conceptual representations that draw together multiple features. We tested these accounts using a novel paradigm that separately manipulated the availability of perceptual information to guide decision-making and the representational complexity of this information...
January 12, 2018: NeuroImage
https://www.readbyqxmd.com/read/29338836/systems-levers-for-commissioning-primary-mental-healthcare-a-rapid-review
#5
Carla Meurk, Meredith Harris, Eryn Wright, Nicola Reavley, Roman Scheurer, Bridget Bassilios, Caroline Salom, Jane Pirkis
Primary Health Networks (PHNs) are a new institution for health systems management in the Australian healthcare system. PHNs will play a key role in mental health reform through planning and commissioning primary mental health services at a regional level, specifically adopting a stepped care approach. Selected PHNs are also trialling a healthcare homes approach. Little is known about the systems levers that could be applied by PHNs to achieve these aims. A rapid review of academic and grey literature published between 2006 and 2016 was undertaken to describe the use of systems levers in commissioning primary care services...
January 17, 2018: Australian Journal of Primary Health
https://www.readbyqxmd.com/read/29338321/are-wishes-for-death-or-suicidal-ideation-symptoms-of-depression-in-older-adults
#6
Rebecca C Rossom, Greg E Simon, Karen J Coleman, Arne Beck, Malia Oliver, Christine Stewart, Brian Ahmedani
OBJECTIVE: Clinicians may question whether thoughts of being better off dead are normal consequences of aging or symptoms of depression. We examine whether thoughts of suicide are as strongly linked to depression severity in older adults as they are in other age groups. METHODS: Cross-sectional cohort study. Participants included 509,945 outpatients >18 years old from four large integrated healthcare systems in the Mental Health Research Network who completed 1...
January 17, 2018: Aging & Mental Health
https://www.readbyqxmd.com/read/29334921/a-pilot-feasibility-randomised-controlled-trial-of-an-adjunct-brief-social-network-intervention-in-opiate-substitution-treatment-services
#7
Ed Day, Alex Copello, Jennifer L Seddon, Marilyn Christie, Deborah Bamber, Charlotte Powell, Carmel Bennett, Shabana Akhtar, Sanju George, Andrew Ball, Emma Frew, Ilias Goranitis, Nick Freemantle
BACKGROUND: Approximately 3% of people receiving opioid substitution therapy (OST) in the UK manage to achieve abstinence from prescribed and illicit drugs within three years of commencing treatment. Involvement of families and wider social networks in supporting psychological treatment may be an effective strategy in facilitating recovery, and this pilot study aimed to evaluate the impact of a social network-focused intervention for patients receiving OST. METHODS: A two-site, open feasibility trial randomised patients receiving OST for at least 12 months but still reporting illicit opiate use in the past 28 days to one of three treatments: 1) treatment as usual (TAU), 2) Brief Social Behaviour and Network Therapy (B-SBNT) + TAU, or 3) Personal Goal Setting (PGS) + TAU...
January 15, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29334640/not-single-brain-areas-but-a-network-is-involved-in-language-applications-in-presurgical-planning
#8
Razieh Alemi, Seyed Amir Hossein Batouli, Ebrahim Behzad, Mitra Ebrahimpoor, Mohammad Ali Oghabian
OBJECTIVES: Language is an important human function, and is a determinant of the quality of life. In conditions such as brain lesions, disruption of the language function may occur, and lesion resection is a solution for that. Presurgical planning to determine the language-related brain areas would enhance the chances of language preservation after the operation; however, availability of a normative language template is essential. PATIENTS AND METHODS: In this study, using data from 60 young individuals who were meticulously checked for mental and physical health, and using fMRI and robust imaging and data analysis methods, functional brain maps for the language production, perception and semantic were produced...
January 10, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29332091/the-association-among-default-mode-network-functional-connectivity-mentalization-and-psychopathology-in-a-nonclinical-sample-an-eloreta-study
#9
Benedetto Farina, Giacomo Della Marca, Giulia Maestoso, Noemi Amoroso, Enrico Maria Valenti, Giuseppe Alessio Carbone, Chiara Massullo, Anna Contardi, Claudio Imperatori
AIMS: We investigated default mode network (DMN) electroencephalography (EEG) functional connectivity differences between individuals with self-reported high mentalization capability and low psychopathological symptoms, versus participants with mentalization impairments and high psychopathological symptoms. METHODS: Forty-nine students (35 women) with a mean age of 22.92 ± 2.53 years were administered the Mentalization Questionnaire (MZQ) and the Symptom Checklist-90-Revised...
January 13, 2018: Psychopathology
https://www.readbyqxmd.com/read/29330217/a-systematic-review-of-network-meta-analyses-for-pharmacological-treatment-of-common-mental-disorders
#10
REVIEW
Taryn Williams, Dan J Stein, Jonathan Ipser
QUESTION: Network meta-analyses (NMAs) of treatment efficacy across different pharmacological treatments help inform clinical decision-making, but their methodological quality may vary a lot depending also on the quality of the included primary studies. We therefore conducted a systematic review of NMAs of pharmacological treatment for common mental disorders in order to assess the methodological quality of these NMAs, and to relate study characteristics to the rankings of efficacy and tolerability...
January 12, 2018: Evidence-based Mental Health
https://www.readbyqxmd.com/read/29327166/loneliness-in-psychosis-a-systematic-review
#11
REVIEW
Michelle H Lim, John F M Gleeson, Mario Alvarez-Jimenez, David L Penn
PURPOSE: The aim of the review is to understand the relationships between loneliness and related psychological and social factors in individuals with psychosis. Loneliness is poorly understood in people with psychosis. Given the myriad of social challenges facing individuals with psychosis, these findings can inform psychosocial interventions that specifically target loneliness in this vulnerable group. METHODS: We adhered to the PRISMA guidelines and systematically reviewed empirical studies that measured loneliness either as a main outcome or as an associated variable in individuals with psychosis...
January 11, 2018: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/29325726/quality-of-life-disparities-between-persons-with-schizophrenia-and-their-professional-caregivers-network-analysis-in-a-national-cohort
#12
Anat Rotstein, David Roe, Marc Gelkopf, Efrat Shadmi, Stephen Z Levine
BACKGROUND: Disparities between mental health patients and their professional caregivers in quality of life appraisals have been identified, however, the structure that such disparities assume is unknown. AIMS: To examine the network structure of quality of life appraisals and disparities using network analysis. METHODS: Participants were 1639 persons with schizophrenia using psychiatric rehabilitation services and their primary professional caregivers (N=582)...
January 8, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29324366/size-matters-the-olfactory-bulb-as-a-marker-for-depression
#13
F Rottstaedt, K Weidner, T Strauß, J Schellong, H Kitzler, S Wolff-Stephan, T Hummel, I Croy
BACKGROUND: Major Depression is mainly related to structural and functional alterations in brain networks involving limbic and prefrontal regions. Reduced olfactory sensitivity in depression is associated with reduced olfactory bulb (OB) volume. We determined if the OB volume reduction is a specific biomarker for depression and whether its diagnostic accuracy allows its use as a valid biomarker to support its diagnosis. METHODS: 84 in-patients with mixed mental disorders and 51 age-matched healthy controls underwent structural MR imaging with a spin-echo T2-wheighted sequence...
December 28, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29318587/new-perspectives-on-the-role-of-melatonin-in-human-sleep-circadian-rhythms-and-their-regulation
#14
REVIEW
N Zisapel
In mammals a central circadian clock, located in the suprachiasmatic nuclei (SCN) of the hypothalamus, tunes the innate circadian physiological rhythms to the ambient 24h light-dark cycle to invigorate and optimize the internal temporal order. The SCN-activated, light- inhibited production of melatonin conveys the message of darkness to the clock and induces night state in physiological function, e.g., sleep/wake blood pressure and metabolism. Clinically meaningful effects of melatonin treatment have been demonstrated in placebo-controlled trials in humans, particularly in disorders associated with diminished or misaligned melatonin rhythms, e...
January 10, 2018: British Journal of Pharmacology
https://www.readbyqxmd.com/read/29318489/neural-correlates-of-reappraisal-considering-working-memory-capacity-and-cognitive-flexibility
#15
Jenny Zaehringer, Rosalux Falquez, Anna-Lena Schubert, Frauke Nees, Sven Barnow
Cognitive reappraisal of emotion is strongly related to long-term mental health. Therefore, the exploration of underlying cognitive and neural mechanisms has become an essential focus of research. Considering that reappraisal and executive functions rely on a similar brain network, the question arises whether behavioral differences in executive functions modulate neural activity during reappraisal. Using functional neuroimaging, the present study aimed to analyze the role of working memory capacity (WMC) and cognitive flexibility in brain activity during down-regulation of negative emotions by reappraisal in N = 20 healthy participants...
January 9, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29307232/health-improvement-and-educational-attainment-in-secondary-schools-complementary-or-competing-priorities-exploratory-analyses-from-the-school-health-research-network-in-wales
#16
Hannah J Littlecott, Sara Long, Jemma Hawkins, Simon Murphy, Gillian Hewitt, Gemma Eccles, Adam Fletcher, Graham F Moore
BACKGROUND: Implementing health improvement is often perceived as diverting resource away from schools' core business, reflecting an assumption of a "zero-sum game" between health and education. There is some evidence that health behaviors may affect young people's educational outcomes. However, associations between implementation of school health improvement and educational outcomes remains underinvestigated. METHODS: The study linked school-level data on free school meal (FSM) entitlement, educational outcomes, and school attendance, obtained from government websites, with data from the School Environment Questionnaire (SEQ) on health improvement activity collected in Wales (2015/2016)...
January 1, 2018: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/29306622/commonly-occurring-adverse-birth-outcomes-and-maternal-depression-a-longitudinal-study
#17
A M Kingsbury, M Plotnikova, J M Najman
OBJECTIVES: Little is known about whether commonly occurring adverse birth outcomes have a long-term impact on the mental health of mothers. The aim of this study was to investigate whether commonly occurring adverse birth outcomes predicted mothers' depressive-symptom trajectories over a 27-year period following the birth of a baby. STUDY DESIGN: Longitudinal study. METHODS: Participants comprised a sub-group of women from the longitudinal cohort of the Mater and University of Queensland Study of Pregnancy...
January 4, 2018: Public Health
https://www.readbyqxmd.com/read/29305824/social-capital-and-health-among-older-chinese-immigrants-a-cross-sectional-analysis-of-a-sample-in-a-canadian-prairie-city
#18
Hai Luo, Verena Menec
The objective of this study was to examine the relationship between social capital and health among Chinese immigrants. The sample included 101 older Chinese immigrants aged 60 to 96 who were recruited in 2013 in a city on the Canadian prairies. Participant completed a questionnaire assessing their structural and cognitive social capital (views on community, trust and reciprocity, civic participation, social networks and support, and social participation), physical and mental health status (SF-36), and sociodemographic characteristics...
January 5, 2018: Journal of Cross-cultural Gerontology
https://www.readbyqxmd.com/read/29305746/verbal-and-nonverbal-anticipatory-mechanisms-in-bilinguals
#19
Lorenzo Desideri, Paola Bonifacci
Empirical evidence collected so far has revealed that the bilingual advantage cannot be reduced to a single component of the executive functioning, and point to the need to understand the effects of bilingual experience on cognition as influencing a wider family of mental processes, including, but not limited to, cognitive control. The present study aims to explore a relatively underinvestigated domain of bilingual cognitive processes, namely anticipation, through a series of different paradigms tapping proactive and reactive mechanisms at different levels of cognitive complexity and linguistic components...
January 5, 2018: Journal of Psycholinguistic Research
https://www.readbyqxmd.com/read/29305437/dementia-in-latin-america-assessing-the-present-and-envisioning-the-future
#20
REVIEW
Mario A Parra, Sandra Baez, Ricardo Allegri, Ricardo Nitrini, Francisco Lopera, Andrea Slachevsky, Nilton Custodio, David Lira, Olivier Piguet, Fiona Kumfor, David Huepe, Patricia Cogram, Thomas Bak, Facundo Manes, Agustin Ibanez
The demographic structure of Latin American countries (LAC) is fast approaching that of developing countries, and the predicted prevalence of dementia in the former already exceeds the latter. Dementia has been declared a global challenge, yet regions around the world show differences in both the nature and magnitude of such a challenge. This article provides evidence and insights on barriers which, if overcome, would enable the harmonization of strategies to tackle the dementia challenge in LAC. First, we analyze the lack of available epidemiologic data, the need for standardizing clinical practice and improving physician training, and the existing barriers regarding resources, culture, and stigmas...
January 5, 2018: Neurology
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