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https://www.readbyqxmd.com/read/27922587/tinea-incognito-due-to-trichophyton-mentagrophytes-case-report
#1
Camila Quiñones, Paula Hasbún, Walter Gubelin
Tineas are frequent infections caused by dermatophytes that are able to invade keratinized tissue, causing rounded, erythematous, scaly lesions. Nonetheless, in tinea incognito the lesions are modified because of inappropriate use of topical corticosteroids or calcineurin inhibitors, making it difficult to diagnose. We present a case of a 12-year-old male child that presents with erythematous lesions on the right eyebrow, which at first was diagnosed as a contact dermatitis, so corticosteroids were indicated...
November 9, 2016: Medwave
https://www.readbyqxmd.com/read/27916265/inflammatory-tinea-manuum-the-importance-of-pustules
#2
Antonio Sahuquillo Torralba, Miguel Ángel Navarro Mira, Rafael Botella Estrada
No abstract text is available yet for this article.
December 1, 2016: Medicina Clínica
https://www.readbyqxmd.com/read/27915299/cathelicidin-ll-37-level-in-the-scalp-hair-of-patients-with-tinea-capitis
#3
Nagwa H Abdelaal, Laila A Rashed, Sahar Y Ibrahim, Mona H Abd El Halim, Noha Ghoneim, Noha A Saleh, Marwah A Saleh
Antimicrobial peptides (AMPs) are considered an important first line of defense against pathogens. Cathelicidin LL-37 was upregulated in response to fungal infection. In this work we aimed to evaluate cathelicidin LL-37 in the hair of tinea capitis and compare it to normal controls. Hair samples were collected from 30 children and 30 controls aged from 2 to10 years old, and the level of cathelicidin LL-37 in the hair was detected by quantitative real-time PCR. The 30 patients were further subdivided into three subgroups according to their clinical type...
December 2, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27904054/epidemiology-of-dermatophytoses-in-crete-greece
#4
Sofia Maraki, Viktoria Eirini Mavromanolaki
Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. The aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in Crete, Greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. We compared our findings with those previously reported from the same area and from other parts of the world...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27903082/itraconazole-induced-thrombocytopenia
#5
Berna Aksoy
Itraconazole is one of the systemic treatment options for extensive tinea versicolor. A male patient who developed thrombocytopenia during the treatment of tinea versicolor by itraconazole is reported in this manuscript. He was diagnosed to develop thrombocytopenia on the third day of treatment. In the literature, there are two reports of itraconazole induced thrombocytopenia both in malignancy patients. One report contained three patients who developed thrombocytopenia as a result of a drug interaction between bortezomib and itraconazole...
November 30, 2016: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/27897199/hydroxychavicol-a-phytochemical-targeting-cutaneous-fungal-infections
#6
Intzar Ali, Naresh Kumar Satti, Prabhu Dutt, Rajendra Prasad, Inshad Ali Khan
The present study was designed to investigate the potency of hydroxychavicol on selected cutaneous human pathogenic fungi by the use of in vitro and in vivo assays and mechanistic characterization along with toxicological effects. Hydroxychavicol consistently displayed a fungicidal effect against all fungal species tested. Inoculum concentrations over the range of 10(4) to 10(7) CFU/ml did not significantly alter its antifungal potential and time-kill curve results revealed concentration-dependent killing...
November 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27892847/international-adoption-from-ethiopia-an-overview-of-the-health-status-at-arrival-in-belgium
#7
Lydia Van Kesteren, Marek Wojciechowski
BACKGROUND: Ethiopia is a densely populated country with a fast growing economy. Still socioeconomic and health issues render many children parentless. One thousand and twenty eight Ethiopian children have been adopted in Belgium from September 2005 to September 2015. Little has been published about their health status at arrival. METHODS: Three hundred and fifteen children adopted from Ethiopia were clinically evaluated at the Institute of Tropical Medicine in Antwerp from 1 January 2008 until 31 December 2014...
November 28, 2016: Acta Clinica Belgica
https://www.readbyqxmd.com/read/27890948/study-of-infections-among-human-immunodeficiency-virus-acquired-immunodeficiency-syndrome-patients-in-shadan-hospital-telangana-india
#8
Sukumar Gajjala Reddy, Syed Yousuf Ali, Azheel Khalidi
BACKGROUND: Human immunodeficiency virus (HIV) pandemicity is a major concern today as it causes greater loss of productivity than any other disease. HIV infection leads to profound immune deficiency and patients become highly susceptible to opportunistic infections (OIs). HIV epidemic in India is heterogeneous in nature, both in terms of routes of transmission as well as geographical spread. AIMS: (1) Determine prevalence of OIs among HIV-seropositive patients and their relation to CD4 count and to focus on the routes of transmission...
July 2016: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27887809/an-estimation-of-burden-of-serious-fungal-infections-in-france
#9
J-P Gangneux, M-E Bougnoux, C Hennequin, C Godet, J Chandenier, D W Denning, B Dupont
OBJECTIVE OF THE STUDY: An estimation of burden of serious fungal diseases in France is essential data to inform public health priorities on the importance of resources and research needed on these infections. In France, precise data are available for invasive fungal diseases but estimates for several other diseases such as chronic and immunoallergic diseases are by contrast less known. MATERIALS AND METHODS: A systematic literature search was conducted using the Web of Science Platform...
November 22, 2016: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/27881134/low-dose-radiation-risks-for-women-surviving-the-a-bombs-in-japan-generalized-additive-model
#10
Greg Dropkin
BACKGROUND: Analyses of cancer mortality and incidence in Japanese A-bomb survivors have been used to estimate radiation risks, which are generally higher for women. Relative Risk (RR) is usually modelled as a linear function of dose. Extrapolation from data including high doses predicts small risks at low doses. Generalized Additive Models (GAMs) are flexible methods for modelling non-linear behaviour. METHODS: GAMs are applied to cancer incidence in female low dose subcohorts, using anonymous public data for the 1958 - 1998 Life Span Study, to test for linearity, explore interactions, adjust for the skewed dose distribution, examine significance below 100 mGy, and estimate risks at 10 mGy...
November 24, 2016: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/27870929/a-clinical-study-of-cutaneous-changes-in-pregnancy
#11
Vinitha V Panicker, Najeeba Riyaz, P K Balachandran
BACKGROUND/OBJECTIVE: Pregnant women experience a myriad of physiological and metabolic changes that affect different organ systems in the body. Cutaneous and appendageal alterations that manifest during pregnancy are largely modulated by hormonal, immunologic, and metabolic factors. Detailed reports encompassing physiological changes and specific dermatoses of pregnancy and effects of various dermatoses on pregnant women are scanty in literature. This study was conducted to examine in detail both physiological changes and specific dermatoses...
November 18, 2016: Journal of Epidemiology and Global Health
https://www.readbyqxmd.com/read/27864837/risk-factors-for-non-purulent-leg-cellulitis-a-systematic-review-and-meta-analysis
#12
REVIEW
M Quirke, F Ayoub, A McCabe, F Boland, B Smith, R O'Sullivan, A Wakai
Non-purulent cellulitis is an acute bacterial infection of the dermal and subdermal tissues that is not associated with purulent drainage, discharge or abscess. The objective of this systematic review and meta-analysis (SRMA) was to identify and appraise all controlled observational studies that have examined risk factors for the development of non-purulent cellulitis of the leg (NPLC). A systematic literature search of electronic databases and grey literature sources was performed in July 2015. The Newcastle-Ottawa Scale (NOS) was used to assess methodological quality of included studies...
November 18, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27846967/tinea-nigra-a-diagnostic-pitfall
#13
Gianluca Nazzaro, Alessandra Ponziani, Stefano Cavicchini
No abstract text is available yet for this article.
December 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27843933/onychomycosis-practical-approaches-to-minimize-relapse-and-recurrence
#14
REVIEW
Antonella Tosti, Boni E Elewski
INTRODUCTION: Toenail onychomycosis is a common disease in which treatment options are limited and treatment failures and disease recurrence are frequently encountered. It usually requires many months of treatment, and recurrence may occur in more than half of the patients within 1 year or more after the infection has been eradicated. Data on long-term treatment, follow-up and recurrence are limited. OBJECTIVE: Our objective is to interpret these data and recommend practical approaches that should minimize recurrence based on our clinical experience...
September 2016: Skin Appendage Disorders
https://www.readbyqxmd.com/read/27843914/trichoscopy-of-focal-alopecia-in-children-new-trichoscopic-findings-hair-bulbs-arranged-radially-along-hair-bearing-margins-in-aplasia-cutis-congenita
#15
Adriana Rakowska, Małgorzata Maj, Małgorzata Zadurska, Joanna Czuwara, Olga Warszawik-Henzel, Małgorzata Olszewska, Lidia Rudnicka
PURPOSE: To establish whether trichoscopy can be useful in the differential diagnosis of patchy alopecia in children. PROCEDURES: The study was a retrospective analysis (2012-2015) and included 68 patients under 6 years of age. The inclusion criteria were age and the presence of 1-3 alopecia patches. A total of 124 alopecia patches were examined with the use of a videodermoscope: 102 alopecia areata, 8 tinea capitis, 6 trichotillomania, 3 temporal triangular alopecia and 5 aplasia cutis congenita...
September 2016: Skin Appendage Disorders
https://www.readbyqxmd.com/read/27825175/update-on-efinaconazole-10-topical-solution-for-the-treatment-of-onychomycosis
#16
A K Gupta, C Studholme
Efinaconazole 10% nail solution is a novel topical antifungal drug for the treatment of onychomycosis. Two Phase III trials were completed using efinaconazole 10% nail solution, where 17.8% and 15.2% of patients achieved complete cure, and 55.2% and 53.4% achieved mycological cure. Several post hoc analyses were carried out using data from Phase III trials to determine the efficacy of efinaconazole with respect to disease duration, disease progression, and comorbidities of diabetes or tinea pedis with onychomycosis...
November 2016: Skin Therapy Letter
https://www.readbyqxmd.com/read/27816294/systemic-antifungal-therapy-for-tinea-capitis-in-children-an-abridged-cochrane-review
#17
Xiaomei Chen, Xia Jiang, Ming Yang, Cathy Bennett, Urbà González, Xiufang Lin, Xia Hua, Siliang Xue, Min Zhang
BACKGROUND: The comparative efficacy and safety profiles of systemic antifungal drugs for tinea capitis in children remain unclear. OBJECTIVE: We sought to assess the effects of systemic antifungal drugs for tinea capitis in children. METHODS: We used standard Cochrane methodological procedures. RESULTS: We included 25 randomized controlled trials with 4449 participants. Terbinafine and griseofulvin had similar effects for children with mixed Trichophyton and Microsporum infections (risk ratio 1...
November 2, 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27799613/mycosis-fungoides-mimicking-tinea-pedis
#18
Steven A Hanna, Mark G Kirchhof
No abstract text is available yet for this article.
December 6, 2016: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/27787643/tinea-unguium-diagnosis-and-treatment-in-practice
#19
Daniel Asz-Sigall, Antonella Tosti, Roberto Arenas
Onychomycosis is caused by dermatophytes, yeasts or non-dermatophyte molds; when caused by dermatophytes, it is called tinea unguium. The main etiological agents are Trichophyton rubrum and Trichophyton interdigitale. The most frequent types are distal and lateral subungual onychomycosis. Diagnosis usually requires mycological laboratory confirmation. Dermoscopy can be helpful and also biopsy is an excellent diagnostic method in uncommon cases or when mycological test is negative. Treatment must be chosen according to clinical type, number of affected nails and severity...
October 27, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27783316/the-changing-face-of-dermatophytic-infections-worldwide
#20
REVIEW
Ping Zhan, Weida Liu
Dermatophytes evolve along with the geography and socioeconomic conditions. Epidermophyton floccosum, Microsporum audouinii and Trichophyton schoenleinii acted as the major pathogens of superficial fungal diseases 100 years ago, but their frequency decreased dramatically since the middle of the twentieth century and they are limited to some less-developed countries nowadays; meanwhile, frequency of Trichophyton rubrum, Trichophyton interdigitale, Trichophyton tonsurans and Microsporum canis increased gradually, and these fungi have become the major species globally...
October 25, 2016: Mycopathologia
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