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Lateral shift

Ala' S Aburub, B Gagnon, S Ahmed, A M Rodríguez, Nancy E Mayo
BACKGROUND: People with cancer may experience change in what constitutes quality of life (QOL) over time as a result of the cancer progression (true change) or adaptation to the experience, considered as a response shift phenomenon. As individualized measures are ideally suited to explore response shift, this study aimed to estimate the extent to which reconceptualization response shift occurred over time in a cancer population and the impact of this response shift on estimates of change on QOL measures...
March 21, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Giuseppe Licari, Joseph S Beckwith, Saeideh Soleimanpour, Stefan Matile, Eric Vauthey
A planarizable push-pull molecular probe with mechanosensitive properties was investigated at several biomimetic interfaces, consisting of different phospholipid monolayers located between dodecane and an aqueous buffer solution, using the interface-specific surface-second-harmonic-generation (SSHG) technique. Whereas the SSHG spectra recorded at liquid-disordered interfaces were similar to the absorption spectra in bulk solutions, those measured at liquid-ordered phases exhibited a remarkable shift towards lower energies to an extent depending on the surface pressure of the phospholipid monolayer...
March 22, 2018: Physical Chemistry Chemical Physics: PCCP
Mohammad Javad Tahmasebi Birgani, Nahid Chegeni, Mansour Zabihzadeh, Marziyeh Tahmasbi
Background: Integrated proton therapy - MRI systems are capable of delivering high doses to the target tissues near sensitive organs and achieve better therapeutic results; however, the applied magnetic field for imaging, influences the protons path, changes the penetration depth and deflects the particles, laterally, leading to dose distribution variations. Objective: To determine the effects of a magnetic field on the range and the lateral deflection of protons, analytically...
December 2017: Electronic Physician
Christos Gournas, Stelios Gkionis, Mélanie Carquin, Laure Twyffels, Donatienne Tyteca, Bruno André
The eukaryotic plasma membrane is compartmentalized into domains enriched in specific lipids and proteins. However, our understanding of the molecular bases and biological roles of this partitioning remains incomplete. The best-studied domain in yeast is the membrane compartment containing the arginine permease Can1 (MCC) and later found to cluster additional transporters. MCCs correspond to static, furrow-like invaginations of the plasma membrane and associate with subcortical structures named "eisosomes" that include upstream regulators of the target of rapamycin complex 2 (TORC2) in the sensing of sphingolipids and membrane stress...
March 20, 2018: Proceedings of the National Academy of Sciences of the United States of America
Anthony Bouillod, Julien Pinot, Aurélien Valade, Johan Cassirame, Georges Soto-Romero, Frédéric Grappe
This study was designed to examine the influence of standing position (vs. seated) during uphill cycling on both mechanical cost (MC) and energy cost (EC) in elite cyclists. For the study, thirteen elite cyclists (VO2max : 71.4 ± 8.0 ml·min-1 ·kg-1 ) performed, in a randomised order, three sets of exercises. Each set comprised 2 min of exercise, alternating every 30 s between seated and standing postures, using different slopes and intensity levels on a motorised treadmill. MC was calculated from the measurement of power output and speed, whereas EC was calculated from the measurement of oxygen consumption and speed...
March 7, 2018: Journal of Biomechanics
Thomas Beez, Hans-Jakob Steiger
Randomized controlled trials (RCTs) are gold standard for comparing treatment modalities. Recently, RCTs transformed ischemic stroke care by first proving benefit of decompressive craniectomy (DC) and later of interventional mechanical thrombectomy. Aim of this study was to explore the impact of RCTs on neurosurgical practice. RCTs investigating DC and thrombectomy were identified. Annual numbers of DCs for ischemic stroke between 2000 and 2017 were determined and correlated with publication dates of RCTs. The initial RCTs demonstrating efficacy of DC were published in 2007, followed by an increase in DC numbers between 2008 and 2009...
March 19, 2018: Neurosurgical Review
Christian Baeumer, Martin Janson, Beate Timmermann, Jörg Wulff
AIM: To assess if apertures shall be mounted upstream or downstream of a range shifting block if these field-shaping devices are combined with the pencil-beam scanning delivery technique (PBS). The lateral dose fall-off served as a benchmark parameter. Both options realizing PBS-with-apertures were compared to the uniform scanning mode. We also evaluated the difference regarding the out-of-field dose caused by interactions of protons in beam-shaping devices.
 Methods: The potential benefit of the downstream configuration over the upstream configuration was estimated analytically...
March 19, 2018: Physics in Medicine and Biology
Laurin Ginner, Tilman Schmoll, Abhishek Kumar, Matthias Salas, Nastassia Pricoupenko, Lara M Wurster, Rainer A Leitgeb
We demonstrate a high-resolution line field en-face time domain optical coherence tomography (OCT) system using an off-axis holography configuration. Line field en-face OCT produces high speed en-face images at rates of up to 100 Hz. The high frame rate favors good phase stability across the lateral field-of-view which is indispensable for digital adaptive optics (DAO). Human retinal structures are acquired in-vivo with a broadband light source at 840 nm, and line rates of 10 kHz to 100 kHz. Structures of different retinal layers, such as photoreceptors, capillaries, and nerve fibers are visualized with high resolution of 2...
February 1, 2018: Biomedical Optics Express
Ruchi Singh, Jagdish C Suri, Renuka Sharma, Tejas Suri, Tulsi Adhikari
OBJECTIVES: To examine the sleep pattern and observe differences in sleep routines, phase preferences, mood, attendance, and academic performance among different adolescent age students. Secondly, to observe the age at which sleep phase transition and changes in sleep requirement become evident. METHODS: A cross-sectional study was conducted among 501 students (aged 11-15 y) of a school in Delhi, India. Students were evaluated for their sleep patterns, sleep duration, habits of napping, quality of sleep, sleepiness, depression, phase preferences by self-reported school sleep habits survey questionnaire along with school performance and attendance...
March 16, 2018: Indian Journal of Pediatrics
Joshua W Joseph, Samuel Davis, Elissa H Wilker, Matthew L Wong, Ori Litvak, Stephen J Traub, Larry A Nathanson, Leon D Sanchez
OBJECTIVES: Emergency physician productivity, often defined as new patients evaluated per hour, is essential to planning clinical operations. Prior research in this area considered this a static quantity; however, our group's study of resident physicians demonstrated significant decreases in hourly productivity throughout shifts. We now examine attending physicians' productivity to determine if it is also dynamic. METHODS: This is a retrospective cohort study, conducted from 2014 to 2016 across three community hospitals in the north-eastern USA, with different schedules and coverage...
March 15, 2018: Emergency Medicine Journal: EMJ
James P Roach, Aleksandra Pidde, Eitan Katz, Jiaxing Wu, Nicolette Ognjanovski, Sara J Aton, Michal R Zochowski
Network oscillations across and within brain areas are critical for learning and performance of memory tasks. While a large amount of work has focused on the generation of neural oscillations, their effect on neuronal populations' spiking activity and information encoding is less known. Here, we use computational modeling to demonstrate that a shift in resonance responses can interact with oscillating input to ensure that networks of neurons properly encode new information represented in external inputs to the weights of recurrent synaptic connections...
March 15, 2018: Proceedings of the National Academy of Sciences of the United States of America
Osamu Takayama, Graciana Puentes
We demonstrate experimentally the lateral circular birefringence of a tunable birefringent polymer, the first example of the spin Hall effect of light in a polymeric material, and we demonstrate that this light shift can be significantly enhanced by tuning the effective birefringence in the polymer. We report experimental observations of this effect using polarimetric techniques and quantum-weak-measurement techniques, reporting a weak amplification factor of 200.
March 15, 2018: Optics Letters
David A Kalmbach, Yu Fang, J Todd Arnedt, Amy L Cochran, Patricia J Deldin, Adam I Kaplin, Srijan Sen
BACKGROUND: Although short sleep, shift work, and physical inactivity are endemic to residency, a lack of objective, real-time information has limited our understanding of how these problems impact physician mental health. OBJECTIVE: To understand how the residency experience affects sleep, physical activity, and mood, and to understand the directional relationships among these variables. DESIGN: A prospective longitudinal study. SUBJECTS: Thirty-three first-year residents (interns) provided data from 2 months pre-internship through the first 6 months of internship...
March 14, 2018: Journal of General Internal Medicine
Sho Tamai, Yasuhiko Hayashi, Yasuo Sasagawa, Masahiro Oishi, Mitsutoshi Nakada
Background: Although it is well known that most choroid plexus cysts (CPCs) are asymptomatic, previous studies have reported that they can infrequently cause progressive hydrocephalus along with their increasing sizes. Among those cases, some patients needed cyst fenestration or cerebrospinal fluid (CSF) diversion to recover neurological deterioration. Meanwhile, some CPCs revealed spontaneous resolution, and in rare cases, they developed re-accumulation. Some reports have described series of radiological findings about their changes in location...
2018: Surgical Neurology International
Felix Stief, André Schmidt, Stefan van Drongelen, Katharina Lenarz, Dara Froemel, Timur Tarhan, Frederick Lutz, Andrea Meurer
A total hip replacement (THR) is a common and routine procedure to reduce pain and restore normal activity. Gait analysis can provide insights into functional characteristics and dynamic joint loading situation not identifiable by clinical examination or static radiographic measures. The present prospective longitudinal study tested whether two years after surgery a THR would restore dynamic loading of the knee and hip joints in the frontal plane to normal. Instrumented gait analysis was performed shortly before surgery and approximately two years after THR on 15 unilateral hip osteoarthritis patients...
March 14, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
Ruyu Yao, Michael Heinrich, Yuanfeng Zou, Eike Reich, Xiaolei Zhang, Yu Chen, Caroline S Weckerle
Goji (fruits of Lycium barbarum L. and L. chinense Mill.) has been used in China as food and medicine for millennia, and globally has been consumed increasingly as a healthy food. Ningxia, with a semi-arid climate, always had the reputation of producing best goji quality ( daodi area). Recently, the increasing market demand pushed the cultivation into new regions with different climates. We therefore ask: How does goji quality differ among production areas of various climatic regions? Historical records are used to trace the spread of goji production in China over time...
2018: Frontiers in Pharmacology
Helena L Rohlf, Anna K Holl, Fabian Kirsch, Barbara Krahé, Birgit Elsner
Previous research has indicated that executive function (EF) is negatively associated with aggressive behavior in childhood. However, there is a lack of longitudinal studies that have examined the effect of deficits in EF on aggression over time and taken into account different forms and functions of aggression at the same time. Furthermore, only few studies have analyzed the role of underlying variables that may explain the association between EF and aggression. The present study examined the prospective paths between EF and different forms (physical and relational) and functions (reactive and proactive) of aggression...
2018: Frontiers in Behavioral Neuroscience
Saul N Rajak, Shyamala C Huilgol, Masahiro Murakami, Dinesh Selva
PURPOSE: Propeller flaps are island flaps that reach the recipient site through an axial rotation. The flap has a subcutaneous pedicle on which it pivots, thereby resembling a helicopter propeller. We present our series of propeller flaps for the reconstruction of large eyelid defects. METHODS: This is a retrospective review of the clinical case notes of eight patients that underwent tumour excision with reconstruction with a cutaneous propeller flap supplied by a non-perforator orbicularis pedicle between July and December 2016...
March 14, 2018: Eye
Takumi Matsumoto, Christopher E Gross, Selene G Parekh
Distal Chevron osteotomy is a well-established surgical procedure for mild to moderate hallux valgus deformity. Many methods have been described for fixation of osteotomy site; secure fixation, enabling large displacement of the metatarsal head, is one of the essentials of this procedure. The purpose of the present study was to evaluate the short-term radiographic outcome of a distal Chevron osteotomy using an intramedullary plate for the correction of hallux valgus deformity. The present study evaluated 37 patients (40 feet) who underwent distal Chevron osteotomy using an intramedullary plate by periodic radiographs obtained preoperatively and at 4 weeks, 8 weeks, 3 months, and 6 months postoperatively...
March 1, 2018: Foot & Ankle Specialist
Yoshikazu Maeda, Yoshitaka Sato, Hiroki Minami, Yutaka Yasukawa, Kazutaka Yamamoto, Hiroyasu Tamamura, Satoshi Shibata, Sayuri Bou, Makoto Sasaki, Yuji Tameshige, Kyo Kume, Hiroshi Ooto, Shigeru Kasahara, Yasuhiro Shimizu, Yusuke Saga, Akira Omoya, Makoto Saitou
PURPOSE: To evaluate the effectiveness of CT image-guided proton radiotherapy for prostate cancer by analyzing the positioning uncertainty and assessing daily dose change due to anatomical variations. MATERIALS AND METHODS: Patients with prostate cancer were treated by opposed lateral proton beams based on a passive scattering method using an in-room CT image-guided system. The system employs a single couch for both CT scanning and beam delivery. The patient was positioned by matching the boundary between the prostate and the rectum's anterior region identified in the CT images to the corresponding boundary in the simulator images after bone matching...
March 12, 2018: Medical Physics
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