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https://www.readbyqxmd.com/read/29765097/bion-in-brazil-supervisions-and-commentaries-edited-by-jose-americo-junqueria-de-mattos-gisele-de-mattos-brito-and-howard-b-levine-karnac-london-2017-262pp
#1
Ian S Miller
No abstract text is available yet for this article.
May 15, 2018: American Journal of Psychoanalysis
https://www.readbyqxmd.com/read/29708415/the-psychotic-part-of-the-personality-bion-s-expeditions-into-unmapped-mental-life
#2
Avner Bergstein
The psychotic part of the personality is seen as a multidimensional mental realm that is fully comprehensible only through intuition and tolerance of approximations, transience, and the notion of infinity. It is suggested that a major differentiating factor between the psychotic and nonpsychotic parts of the personality is the capacity to tolerate the infinite complexity of the human mind. With the use of mathematical concepts, Bion tries to describe the state of mind required of the analyst who endeavors to tread on psychotic territories of the personality...
April 2018: Journal of the American Psychoanalytic Association
https://www.readbyqxmd.com/read/29704407/design-of-interactions-between-nanomaterials-and-proteins-a-highly-affine-peptide-tag-to-bare-iron-oxide-nanoparticles-for-magnetic-protein-separation
#3
Sebastian P Schwaminger, Silvia A Blank-Shim, Isabell Scheifele, Vitaliy Pipich, Paula Fraga-García, Sonja Berensmeier
Superparamagnetic nanoparticles have recently gained much attention due to their broad range of applicability including medical in vivo technologies, sensors and as supports for catalysts. As magnetic affinity materials, they can be utilized for the development of new purification strategies for pharmaceuticals and other target molecules from crude lysates. Here, a short peptide tag based on a glutamate sequence is introduced and the adsorption of pure protein as well as protein from crude cell lysate at different conditions is demonstrated...
April 28, 2018: Biotechnology Journal
https://www.readbyqxmd.com/read/29609526/stromal-and-hematopoietic-progenitors-from-c57-bi-6n-murine-bone-marrow-after-30-day-bion-m1-space-flight
#4
Elena Markina, Elena Andreeva, Irina Andrianova, Elena Sotnezova, Ludmila Buravkova
Elucidation of the space flight effects on the adult stem and progenitor cells is an important goal in space biology and medicine. A unique opportunity for this was provided by project "BION-M1". The purpose of this study was to evaluate the effects of 30-day space flight (SF) on biosatellite, 7-day recovery (SFR) and subsequent ground control (GC) experiment on the mononuclears (MNCs) from C57/BI/6N murine tibia bone marrow. Also, hematopoietic and stromal precursor functions were characterised ex vivo...
April 2, 2018: Stem Cells and Development
https://www.readbyqxmd.com/read/29562975/the-bion-project-and-the-history-of-post-spaceflight-primate-anesthesia
#5
Matthieu Komorowski, Mark R Campbell
No abstract text is available yet for this article.
April 1, 2018: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/29476025/protocol-for-the-health-economic-evaluation-of-increasing-the-weekend-specialist-to-patient-ratio-in-hospitals-in-england
#6
Samuel I Watson, Yen-Fu Chen, Julian F Bion, Cassie P Aldridge, Alan Girling, Richard J Lilford
INTRODUCTION: This protocol concerns the evaluation of increased specialist staffing at weekends in hospitals in England. Seven-day health services are a key policy for the UK government and other health systems trying to improve use of infrastructure and resources. A particular motivation for the 7-day policy has been the observed increase in the risk of death associated with weekend admission, which has been attributed to fewer hospital specialists being available at weekends. However, the causes of the weekend effect have not been adequately characterised; many of the excess deaths associated with the 'weekend effect' may not be preventable, and the presumed benefits of improved specialist cover might be offset by the cost of implementation...
February 23, 2018: BMJ Open
https://www.readbyqxmd.com/read/29475516/exposure-to-microgravity-for-30-days-onboard-bion-m1-caused-muscle-atrophy-and-impaired-regeneration-in-murine-femoral-quadriceps
#7
E A Radugina, E A C Almeida, E Blaber, V A Poplinskaya, Y V Markitantova, E N Grigoryan
Mechanical unloading in microgravity during spaceflight is known to cause muscular atrophy, changes in muscle fiber composition, gene expression, and reduction in regenerative muscle growth. Although some limited data exists for long-term effects of microgravity in human muscle, these processes have mostly been studied in rodents for short periods of time. Here we report on how long-term (30-day long) mechanical unloading in microgravity affects murine muscles of the femoral Quadriceps group. To conduct these studies we used muscle tissue from 6 microgravity mice, in comparison to habitat (7), and vivarium (14) ground control mice from the NASA Biospecimen Sharing Program conducted in collaboration with the Institute for Biomedical Problems of the Russian Academy of Sciences, during the Russian Bion M1 biosatellite mission in 2013...
February 2018: Life Sciences in Space Research
https://www.readbyqxmd.com/read/29337659/determination-of-five-tetracyclines-and-their-epimers-by-lc-ms-ms-based-on-a-liquid-liquid-extraction-with-low-temperature-partitioning
#8
Aurélien Desmarchelier, Sébastien Anizan, Mai Minh Tien, Marie-Claude Savoy, Cindy Bion
An LC-MS/MS method is presented for screening five tetracyclines and their epimers in a broad range of food products. The scope of matrices includes meat-, fish-, seafood-based products, various dairy ingredients, infant formulae and fats. The method principle is based on a liquid-liquid extraction with aqueous ethylenediaminetetraacetic acid (EDTA) and acetonitrile followed by a freezing step to promote phase separation at low temperature. After defatting with hexane, sample extracts were evaporated and reconstituted before injection onto the LC-MS/MS system...
April 2018: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29327617/presence-mourning-and-beauty-elements-of-analytic-process
#9
Henry C Markman
Analyst and patient occasionally arrive at moments of heightened meaning and aliveness. These moments can be transformative and lead to psychic change in the patient. They give life and arouse hope, and feel "real" in a new way, though often entailing emotional turbulence. Specific internal work must be done by the analyst to allow for and foster these experiences. This involves a kind of mourning process in the analyst that allows for "presence" and "availability" as described by Gabriel Marcel, and for the "at-one-ment" described by Bion...
December 2017: Journal of the American Psychoanalytic Association
https://www.readbyqxmd.com/read/29275347/two-epoch-cross-sectional-case-record-review-protocol-comparing-quality-of-care-of-hospital-emergency-admissions-at-weekends-versus-weekdays
#10
Julian Bion, Cassie P Aldridge, Alan Girling, Gavin Rudge, Chris Beet, Tim Evans, R Mark Temple, Chris Roseveare, Mike Clancy, Amunpreet Boyal, Carolyn Tarrant, Elizabeth Sutton, Jianxia Sun, Peter Rees, Russell Mannion, Yen-Fu Chen, Samuel Ian Watson, Richard Lilford
INTRODUCTION: The mortality associated with weekend admission to hospital (the 'weekend effect') has for many years been attributed to deficiencies in quality of hospital care, often assumed to be due to suboptimal senior medical staffing at weekends. This protocol describes a case note review to determine whether there are differences in care quality for emergency admissions (EAs) to hospital at weekends compared with weekdays, and whether the difference has reduced over time as health policies have changed to promote 7-day services...
December 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29235679/from-extension-to-revolutionary-change-in-clinical-psychoanalysis-the-radical-influence-of-bion-and-winnicott
#11
Ofra Eshel
This paper addresses the radical departure of late Bion's and Winnicott's clinical ideas and practices from traditional psychoanalytic work, introducing a revolutionary change in clinical psychoanalysis. The profound significance and implications of their thinking are explored, and in particular Bion's conception of transformation in O and Winnicott's clinical-technical revision of analytic work, with its emphasis on regression in the treatment of more disturbed patients. The author specifically connects the unknown and unknowable emotional reality-O with unthinkable breakdown (Winnicott) and catastrophe (Bion)...
October 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/29163058/adaptive-changes-in-the-vestibular-system-of-land-snail-to-a-30-day-spaceflight-and-readaptation-on-return-to-earth
#12
Nikolay Aseyev, Alia Kh Vinarskaya, Matvey Roshchin, Tatiana A Korshunova, Aleksey Yu Malyshev, Alena B Zuzina, Victor N Ierusalimsky, Maria S Lemak, Igor S Zakharov, Ivan A Novikov, Peter Kolosov, Ekaterina Chesnokova, Svetlana Volkova, Artem Kasianov, Leonid Uroshlev, Yekaterina Popova, Richard D Boyle, Pavel M Balaban
The vestibular system receives a permanent influence from gravity and reflexively controls equilibrium. If we assume gravity has remained constant during the species' evolution, will its sensory system adapt to abrupt loss of that force? We address this question in the land snail Helix lucorum exposed to 30 days of near weightlessness aboard the Bion-M1 satellite, and studied geotactic behavior of postflight snails, differential gene expressions in statocyst transcriptome, and electrophysiological responses of mechanoreceptors to applied tilts...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28987982/a-qualitative-study-of-speaking-out-about-patient-safety-concerns-in-intensive-care-units
#13
Carolyn Tarrant, Myles Leslie, Julian Bion, Mary Dixon-Woods
Much policy focus has been afforded to the role of "whistleblowers" in raising concerns about quality and safety of patient care in healthcare settings. However, most opportunities for personnel to identify and act on these concerns are likely to occur much further upstream, in the day-to-day mundane interactions of everyday work. Using qualitative data from over 900 h of ethnographic observation and 98 interviews across 19 English intensive care units (ICUs), we studied how personnel gave voice to concerns about patient safety or poor practice...
November 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28973283/cytomegalovirus-in-patients-in-the-intensive-care-unit-reply
#14
Nicholas J Cowley, Paul Moss, Julian F Bion
No abstract text is available yet for this article.
October 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28900902/derivation-and-validation-of-a-prognostic-model-for-postoperative-risk-stratification-of-critically-ill-patients-with-faecal-peritonitis
#15
Ascanio Tridente, Julian Bion, Gary H Mills, Anthony C Gordon, Geraldine M Clarke, Andrew Walden, Paula Hutton, Paul A H Holloway, Jean-Daniel Chiche, Frank Stuber, Christopher Garrard, Charles Hinds
BACKGROUND: Prognostic scores and models of illness severity are useful both clinically and for research. The aim of this study was to develop two prognostic models for the prediction of long-term (6 months) and 28-day mortality of postoperative critically ill patients with faecal peritonitis (FP). METHODS: Patients admitted to intensive care units with faecal peritonitis and recruited to the European GenOSept study were divided into a derivation and a geographical validation subset; patients subsequently recruited to the UK GAinS study were used for temporal validation...
September 12, 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28899175/bion-s-agony-in-the-long-week-end
#16
Robert Ehrlich
In The Long Week-End Wilfred Bion focuses on his emotional distress during the first twenty-one years of his life. Rarely employing psychoanalytic terminology, he attempts to explore his emotional experience directly, struggling to find a language that could capture the complexity of inner life. Central to The Long Week-End is his desire to communicate how easily he could feel unintelligent, inept, weak, ashamed, guilty, angry, frightened, and cowardly in various settings. This self-criticism at times undermines his theoretical stance in this work, as he emphasizes the importance of doubt and uncertainty when attempting to comprehend most dimensions of experience...
August 2017: Journal of the American Psychoanalytic Association
https://www.readbyqxmd.com/read/28875158/thirty-days-of-spaceflight-does-not-alter-murine-calvariae-structure-despite-increased-sost-expression
#17
Timothy R Macaulay, Jamila H Siamwala, Alan R Hargens, Brandon R Macias
Previously our laboratory documented increases in calvaria bone volume and thickness in mice exposed to 15 days of spaceflight aboard the NASA Shuttle mission STS-131. However, the tissues were not processed for gene expression studies to determine what bone formation pathways might contribute to these structural adaptations. Therefore, this study was designed to investigate both the structural and molecular changes in mice calvariae after a longer duration of spaceflight. The primary purpose was to determine the calvaria bone volume and thickness of mice exposed to 30 days of spaceflight using micro-computed tomography for comparison with our previous findings...
December 2017: Bone Reports
https://www.readbyqxmd.com/read/28873760/butter-serums-and-buttermilks-as-sources-of-bioactive-lipids-from-the-milk-fat-globule-membrane-differences-in-their-lipid-composition-and-potentialities-of-cow-diet-to-increase-n-3-pufa
#18
Christelle Lopez, Marielle Blot, Valérie Briard-Bion, Carole Cirié, Benoit Graulet
Improving the nutritional and health properties of food products, e.g. infant milk formula, by the addition of functional ingredients is of primary importance. This study focused on bioactive milk polar lipids (PLs) recovered from dietary sources that are of increasing interest. The chemical compositions of buttermilks and butter serums were determined and the modulation of the fatty acid composition of milk PLs was investigated. Butter serums contain a higher amount of milk PLs than buttermilks (88 vs. 13-18g/kg dry matter), with a higher proportion of sphingomyelin (34 vs...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28821629/effects-of-spaceflight-on-the-muscles-of-the-murine-shoulder
#19
Hua Shen, Chanteak Lim, Andrea G Schwartz, Alexander Andreev-Andrievskiy, Alix C Deymier, Stavros Thomopoulos
Mechanical loading is necessary for the development and maintenance of the musculoskeletal system. Removal of loading via microgravity, paralysis, or bed rest leads to rapid loss of muscle mass and function; however, the molecular mechanisms that lead to these changes are largely unknown, particularly for the spaceflight (SF) microgravity environment. Furthermore, few studies have explored these effects on the shoulder, a dynamically stabilized joint with a large range of motion; therefore, we examined the effects of microgravity on mouse shoulder muscles for the 15-d Space Transportation System (STS)-131, 13-d STS-135, and 30-d Bion-M1 missions...
December 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28815713/clinical-winnicott-traveling-a-revolutionary-road
#20
Vincenzo Bonaminio
The author contends that, contrary to the usual perception that Winnicott followed a linear progression "through pediatrics to psychoanalysis," Winnicott's vision was always a psychoanalytic one, even during his early pediatric work. His place in the development of psychoanalytic theory is highlighted, and the author discusses such key Winnicottian concepts as transitional space, the false self, and the use of the object. Winnicott's unique approach to the form and value of analytic interpretation is particularly emphasized, and his thoughts on the treatment of depression are also addressed, as well as his distinction between regression and withdrawal...
July 2017: Psychoanalytic Quarterly
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