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https://www.readbyqxmd.com/read/29327617/presence-mourning-and-beauty-elements-of-analytic-process
#1
Henry C Markman
Analyst and patient occasionally arrive at moments of heightened meaning and aliveness. These moments can be transformative and lead to psychic change in the patient. They give life and arouse hope, and feel "real" in a new way, though often entailing emotional turbulence. Specific internal work must be done by the analyst to allow for and foster these experiences. This involves a kind of mourning process in the analyst that allows for "presence" and "availability" as described by Gabriel Marcel, and for the "at-one-ment" described by Bion...
December 2017: Journal of the American Psychoanalytic Association
https://www.readbyqxmd.com/read/29275347/two-epoch-cross-sectional-case-record-review-protocol-comparing-quality-of-care-of-hospital-emergency-admissions-at-weekends-versus-weekdays
#2
Julian Bion, Cassie P Aldridge, Alan Girling, Gavin Rudge, Chris Beet, Tim Evans, R Mark Temple, Chris Roseveare, Mike Clancy, Amunpreet Boyal, Carolyn Tarrant, Elizabeth Sutton, Jianxia Sun, Peter Rees, Russell Mannion, Yen-Fu Chen, Samuel Ian Watson, Richard Lilford
INTRODUCTION: The mortality associated with weekend admission to hospital (the 'weekend effect') has for many years been attributed to deficiencies in quality of hospital care, often assumed to be due to suboptimal senior medical staffing at weekends. This protocol describes a case note review to determine whether there are differences in care quality for emergency admissions (EAs) to hospital at weekends compared with weekdays, and whether the difference has reduced over time as health policies have changed to promote 7-day services...
December 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29235679/from-extension-to-revolutionary-change-in-clinical-psychoanalysis-the-radical-influence-of-bion-and-winnicott
#3
Ofra Eshel
This paper addresses the radical departure of late Bion's and Winnicott's clinical ideas and practices from traditional psychoanalytic work, introducing a revolutionary change in clinical psychoanalysis. The profound significance and implications of their thinking are explored, and in particular Bion's conception of transformation in O and Winnicott's clinical-technical revision of analytic work, with its emphasis on regression in the treatment of more disturbed patients. The author specifically connects the unknown and unknowable emotional reality-O with unthinkable breakdown (Winnicott) and catastrophe (Bion)...
October 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/29163058/adaptive-changes-in-the-vestibular-system-of-land-snail-to-a-30-day-spaceflight-and-readaptation-on-return-to-earth
#4
Nikolay Aseyev, Alia Kh Vinarskaya, Matvey Roshchin, Tatiana A Korshunova, Aleksey Yu Malyshev, Alena B Zuzina, Victor N Ierusalimsky, Maria S Lemak, Igor S Zakharov, Ivan A Novikov, Peter Kolosov, Ekaterina Chesnokova, Svetlana Volkova, Artem Kasianov, Leonid Uroshlev, Yekaterina Popova, Richard D Boyle, Pavel M Balaban
The vestibular system receives a permanent influence from gravity and reflexively controls equilibrium. If we assume gravity has remained constant during the species' evolution, will its sensory system adapt to abrupt loss of that force? We address this question in the land snail Helix lucorum exposed to 30 days of near weightlessness aboard the Bion-M1 satellite, and studied geotactic behavior of postflight snails, differential gene expressions in statocyst transcriptome, and electrophysiological responses of mechanoreceptors to applied tilts...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28987982/a-qualitative-study-of-speaking-out-about-patient-safety-concerns-in-intensive-care-units
#5
Carolyn Tarrant, Myles Leslie, Julian Bion, Mary Dixon-Woods
Much policy focus has been afforded to the role of "whistleblowers" in raising concerns about quality and safety of patient care in healthcare settings. However, most opportunities for personnel to identify and act on these concerns are likely to occur much further upstream, in the day-to-day mundane interactions of everyday work. Using qualitative data from over 900 h of ethnographic observation and 98 interviews across 19 English intensive care units (ICUs), we studied how personnel gave voice to concerns about patient safety or poor practice...
November 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28973283/cytomegalovirus-in-patients-in-the-intensive-care-unit-reply
#6
Nicholas J Cowley, Paul Moss, Julian F Bion
No abstract text is available yet for this article.
October 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28900902/derivation-and-validation-of-a-prognostic-model-for-postoperative-risk-stratification-of-critically-ill-patients-with-faecal-peritonitis
#7
Ascanio Tridente, Julian Bion, Gary H Mills, Anthony C Gordon, Geraldine M Clarke, Andrew Walden, Paula Hutton, Paul A H Holloway, Jean-Daniel Chiche, Frank Stuber, Christopher Garrard, Charles Hinds
BACKGROUND: Prognostic scores and models of illness severity are useful both clinically and for research. The aim of this study was to develop two prognostic models for the prediction of long-term (6 months) and 28-day mortality of postoperative critically ill patients with faecal peritonitis (FP). METHODS: Patients admitted to intensive care units with faecal peritonitis and recruited to the European GenOSept study were divided into a derivation and a geographical validation subset; patients subsequently recruited to the UK GAinS study were used for temporal validation...
September 12, 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28899175/bion-s-agony-in-the-long-week-end
#8
Robert Ehrlich
In The Long Week-End Wilfred Bion focuses on his emotional distress during the first twenty-one years of his life. Rarely employing psychoanalytic terminology, he attempts to explore his emotional experience directly, struggling to find a language that could capture the complexity of inner life. Central to The Long Week-End is his desire to communicate how easily he could feel unintelligent, inept, weak, ashamed, guilty, angry, frightened, and cowardly in various settings. This self-criticism at times undermines his theoretical stance in this work, as he emphasizes the importance of doubt and uncertainty when attempting to comprehend most dimensions of experience...
August 2017: Journal of the American Psychoanalytic Association
https://www.readbyqxmd.com/read/28875158/thirty-days-of-spaceflight-does-not-alter-murine-calvariae-structure-despite-increased-sost-expression
#9
Timothy R Macaulay, Jamila H Siamwala, Alan R Hargens, Brandon R Macias
Previously our laboratory documented increases in calvaria bone volume and thickness in mice exposed to 15 days of spaceflight aboard the NASA Shuttle mission STS-131. However, the tissues were not processed for gene expression studies to determine what bone formation pathways might contribute to these structural adaptations. Therefore, this study was designed to investigate both the structural and molecular changes in mice calvariae after a longer duration of spaceflight. The primary purpose was to determine the calvaria bone volume and thickness of mice exposed to 30 days of spaceflight using micro-computed tomography for comparison with our previous findings...
December 2017: Bone Reports
https://www.readbyqxmd.com/read/28873760/butter-serums-and-buttermilks-as-sources-of-bioactive-lipids-from-the-milk-fat-globule-membrane-differences-in-their-lipid-composition-and-potentialities-of-cow-diet-to-increase-n-3-pufa
#10
Christelle Lopez, Marielle Blot, Valérie Briard-Bion, Carole Cirié, Benoit Graulet
Improving the nutritional and health properties of food products, e.g. infant milk formula, by the addition of functional ingredients is of primary importance. This study focused on bioactive milk polar lipids (PLs) recovered from dietary sources that are of increasing interest. The chemical compositions of buttermilks and butter serums were determined and the modulation of the fatty acid composition of milk PLs was investigated. Butter serums contain a higher amount of milk PLs than buttermilks (88 vs. 13-18g/kg dry matter), with a higher proportion of sphingomyelin (34 vs...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28821629/effects-of-spaceflight-on-the-muscles-of-the-murine-shoulder
#11
Hua Shen, Chanteak Lim, Andrea G Schwartz, Alexander Andreev-Andrievskiy, Alix C Deymier, Stavros Thomopoulos
Mechanical loading is necessary for the development and maintenance of the musculoskeletal system. Removal of loading via microgravity, paralysis, or bed rest leads to rapid loss of muscle mass and function; however, the molecular mechanisms that lead to these changes are largely unknown, particularly for the spaceflight (SF) microgravity environment. Furthermore, few studies have explored these effects on the shoulder, a dynamically stabilized joint with a large range of motion; therefore, we examined the effects of microgravity on mouse shoulder muscles for the 15-d Space Transportation System (STS)-131, 13-d STS-135, and 30-d Bion-M1 missions...
August 17, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28815713/clinical-winnicott-traveling-a-revolutionary-road
#12
Vincenzo Bonaminio
The author contends that, contrary to the usual perception that Winnicott followed a linear progression "through pediatrics to psychoanalysis," Winnicott's vision was always a psychoanalytic one, even during his early pediatric work. His place in the development of psychoanalytic theory is highlighted, and the author discusses such key Winnicottian concepts as transitional space, the false self, and the use of the object. Winnicott's unique approach to the form and value of analytic interpretation is particularly emphasized, and his thoughts on the treatment of depression are also addressed, as well as his distinction between regression and withdrawal...
July 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/28805685/re-adaption-on-earth-after-spaceflights-affects-the-mouse-liver-proteome
#13
Viktoria Anselm, Svetlana Novikova, Victor Zgoda
Harsh environmental conditions including microgravity and radiation during prolonged spaceflights are known to alter hepatic metabolism. Our studies have focused on the analysis of possible changes in metabolic pathways in the livers of mice from spaceflight project "Bion-M 1". Mice experienced 30 days of spaceflight with and without an additional re-adaption period of seven days compared to control mice on Earth. To investigate mice livers we have performed proteomic profiling utilizing shotgun mass spectrometry followed by label-free quantification...
August 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28805053/heterogeneous-photochemistry-of-agrochemicals-at-the-leaf-surface-a-case-study-of-plant-activator-acibenzolar-s-methyl
#14
M Sleiman, P de Sainte Claire, C Richard
The photoreactivity of plant activator benzo(1,2,3)thiadiazole-7-carbothioic acid S-methyl ester (BTH), commonly named acibenzolar-S-methyl, was studied on the surfaces of glass, paraffinic wax films, and apple leaves. Experiments were carried out in a solar simulator using pure and formulated BTH (BION). Surface photoproducts were identified using liquid chromatography coupled with electrospray ionization and high-resolution Orbitrap mass spectrometry, while volatile photoproducts were characterized using an online thermal desorption system coupled to a gas chromatography-mass spectrometry (GC-MS) system...
September 6, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28776654/the-latency-complex-the-dead-hand-of-anti-development
#15
Barry D Proner
It is common knowledge that the same phenomena can be viewed in a variety of ways. This paper considers the implications of a constellation observed in some adult patients who have increasingly reminded the author of some of the children of latency age with whom he has also worked. In the literature these patients may also have been thought about in terms of 'defences of the self' (Fordham), patients who are 'difficult to reach' (Joseph), 'psychic retreats' (Steiner), and those who make 'attacks on linking' (Bion)...
September 2017: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/28751192/evidence-of-an-inverse-correlation-between-serotonergic-activity-and-spreading-depression-propagation-in-the-rat-cortex
#16
Rubem Carlos Araújo Guedes, Maria das Graças Rodrigues de Araújo, Taciana Cristovam Verçosa, Francisca Martins Bion, Andrea Lima de Sá, Antônio Pereira, Ricardo Abadie-Guedes
Various neurological and psychiatric diseases lead to alterations in cortical serotonergic activity as one of their underlying processes. However, the electrophysiological implication of changes in serotonergic activity remains a matter of investigation. In this study, we investigated whether brain serotonergic activity influences the excitability-related phenomenon known as cortical spreading depression (CSD). CSD parameters (propagation velocity, and amplitude and duration of the DC-shift) was evaluated in rats that received two treatments that increased cortical serotonergic activity, electrical stimulation of the raphe nuclei and subcutaneous injection of a selective serotonin reuptake inhibitor, sumatriptan...
October 1, 2017: Brain Research
https://www.readbyqxmd.com/read/28723146/generalized-noise-study-of-solid-state-nanopores-at-low-frequencies
#17
Chenyu Wen, Shuangshuang Zeng, Kai Arstila, Timo Sajavaara, Yu Zhu, Zhen Zhang, Shi-Li Zhang
Nanopore technology has been extensively investigated for analysis of biomolecules, and a success story in this field concerns DNA sequencing using a nanopore chip featuring an array of hundreds of biological nanopores (BioNs). Solid-state nanopores (SSNs) have been explored to attain longer lifetime and higher integration density than what BioNs can offer, but SSNs are generally considered to generate higher noise whose origin remains to be confirmed. Here, we systematically study low-frequency (including thermal and flicker) noise characteristics of SSNs measuring 7 to 200 nm in diameter drilled through a 20-nm-thick SiNx membrane by focused ion milling...
February 24, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28710944/effect-of-acibenzolar-s-methyl-phototransformation-on-its-elicitation-activity-in-tobacco-cells
#18
Florent Lavergne, Claire Richard, Marc Saudreau, Jean-Stéphane Venisse, Boris Fumanal, Pascale Goupil
The plant activator acibenzolar-S-methyl (BTH) undergoes phototransformation when exposed to solar radiation. Here we investigated the changes in its elicitation properties on BY-2 tobacco cells at different stages of the photochemical reaction. Both pure BTH and formulated BTH were irradiated in controlled conditions to achieve different extents of conversion. Both pure BTH (900 μM) and Bion(®) (0.4 g.L(-1)) induced BY-2 cell death, but BTH photoconverted to an extent of 25 ± 3% lowered the cell death rate...
July 8, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28607344/surviving-sepsis-campaign-guidelines-2016-omission-of-selective-decontamination-of-the-digestive-tract-deprives-patients-of-a-level-2b-therapy
#19
Luciano Silvestri, Hendrick K van Saene, Johannes H Rommes, Andy J Petros, Miguel A de la Cal, Julian F Bion
No abstract text is available yet for this article.
June 12, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28590761/proteome-wide-adaptations-of-mouse-skeletal-muscles-during-a-full-month-in-space
#20
Georg Tascher, Thomas Brioche, Pauline Maes, Angèle Chopard, Donal O'Gorman, Guillemette Gauquelin-Koch, Stéphane Blanc, Fabrice Bertile
The safety of space flight is challenged by a severe loss of skeletal muscle mass, strength, and endurance that may compromise the health and performance of astronauts. The molecular mechanisms underpinning muscle atrophy and decreased performance have been studied mostly after short duration flights and are still not fully elucidated. By deciphering the muscle proteome changes elicited in mice after a full month aboard the BION-M1 biosatellite, we observed that the antigravity soleus incurred the greatest changes compared with locomotor muscles...
June 20, 2017: Journal of Proteome Research
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