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Post natal depression

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https://www.readbyqxmd.com/read/28675061/postnatal-depression-maternal-infant-bonding-and-social-support-a-cross-cultural-comparison-of-nigerian-and-british-mothers
#1
Oladayo Afolabi, Louise Bunce, Joanne Lusher, Samantha Banbury
OBJECTIVES: The high prevalence of Post-Natal Depression (PND) in low and lower-middle income countries of Africa raises questions about the functionality of the abundant informal support accessed in the enmeshed family structure. This study examined the interaction between social support, parity and culture in the development of PND and maternal-infant bonding (MIB) among Nigerian, British and Nigerian Immigrant mothers in the UK. METHODS: Participants (N = 124) were recruited from the UK and Nigeria via local support groups for mothers, websites offering motherhood-related content and social media...
July 4, 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28666895/the-microbiome-and-disorders-of-the-central-nervous-system
#2
Valeria D Felice, Siobhain M O'Mahony
Alterations of the gut microbiota have been associated with stress-related disorders including depression and anxiety and irritable bowel syndrome (IBS). More recently, researchers have started investigating the implication of perturbation of the microbiota composition in neurodevelopmental disorders including autism spectrum disorders and Attention-Deficit Hypersensitivity Disorder (ADHD). In this review we will discuss how the microbiota is established and its functions in maintaining health. We also summarize both pre and post-natal factors that shape the developing neonatal microbiota and how they may impact on health outcomes with relevance to disorders of the central nervous system...
June 27, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28654017/does-vitamin-c-influence-neurodegenerative-diseases-and-psychiatric-disorders
#3
REVIEW
Joanna Kocot, Dorota Luchowska-Kocot, Małgorzata Kiełczykowska, Irena Musik, Jacek Kurzepa
Vitamin C (Vit C) is considered to be a vital antioxidant molecule in the brain. Intracellular Vit C helps maintain integrity and function of several processes in the central nervous system (CNS), including neuronal maturation and differentiation, myelin formation, synthesis of catecholamine, modulation of neurotransmission and antioxidant protection. The importance of Vit C for CNS function has been proven by the fact that targeted deletion of the sodium-vitamin C co-transporter in mice results in widespread cerebral hemorrhage and death on post-natal day one...
June 27, 2017: Nutrients
https://www.readbyqxmd.com/read/28600701/the-impact-of-exposure-to-antidepressant-medications-during-pregnancy-on-neonatal-outcomes-a-review-of-retrospective-database-cohort-studies
#4
REVIEW
Casey R Tak, Kathleen M Job, Katie Schoen-Gentry, Sarah C Campbell, Patrick Carroll, Maged Costantine, Diana Brixner, Angela K Birnbaum, Catherine M T Sherwin
INTRODUCTION: Concerns with prescription antidepressant use in pregnant women have instigated the examination of potential associations between fetal exposure to antidepressant medication and outcomes including preterm delivery, congenital malformations, perinatal and post-natal adverse events, persistent pulmonary hypertension, and mortality. The retrospective cohort model is an often utilized study design. The objective of this review is to evaluate the literature on antidepressant use in pregnancy conducted as retrospective cohorts in national/regional medical, or claims databases that assess neonatal and infant outcomes for agreement between studies, ultimately providing a methodological and outcomes summary for future scientific endeavors...
June 9, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28588541/parenting-stress-mental-health-dyadic-adjustment-a-structural-equation-model
#5
Luca Rollè, Laura E Prino, Cristina Sechi, Laura Vismara, Erica Neri, Concetta Polizzi, Annamaria Trovato, Barbara Volpi, Sara Molgora, Valentina Fenaroli, Elena Ierardi, Valentino Ferro, Loredana Lucarelli, Francesca Agostini, Renata Tambelli, Emanuela Saita, Cristina Riva Crugnola, Piera Brustia
Objective: In the 1st year of the post-partum period, parenting stress, mental health, and dyadic adjustment are important for the wellbeing of both parents and the child. However, there are few studies that analyze the relationship among these three dimensions. The aim of this study is to investigate the relationships between parenting stress, mental health (depressive and anxiety symptoms), and dyadic adjustment among first-time parents. Method: We studied 268 parents (134 couples) of healthy babies. At 12 months post-partum, both parents filled out, in a counterbalanced order, the Parenting Stress Index-Short Form, the Edinburgh Post-natal Depression Scale, the State-Trait Anxiety Inventory, and the Dyadic Adjustment Scale...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28570858/chronological-narratives-from-smoking-initiation-through-to-pregnancy-of-indigenous-australian-women-a-qualitative-study
#6
Gillian S Gould, Michelle Bovill, Marilyn J Clarke, Maree Gruppetta, Yvonne Cadet-James, Billie Bonevski
OBJECTIVE: One in two Indigenous Australian pregnant women smoke, yet little is known about their trajectory of smoking. This study aimed to explore Aboriginal women's narratives from starting smoking through to pregnancy. METHODS: A female Aboriginal Researcher conducted individual face-to-face interviews with 20 Aboriginal women from New South Wales, Australia. Recruitment, through Aboriginal services and community networks, continued until saturation was reached...
May 19, 2017: Midwifery
https://www.readbyqxmd.com/read/28527907/behavioral-and-cognitive-impact-of-early-life-stress-insights-from-an-animal-model
#7
Hesong Liu, Fatin Atrooz, Ankita Salvi, Samina Salim
BACKGROUND: Children subjected to traumatic events during childhood are reported to exhibit behavioral and cognitive deficits later in life, often leading to post-traumatic stress disorder (PTSD) and major depression. Interestingly, some children continue to remain normal despite being exposed to the same risk factors. These trauma-related behavioral and cognitive profiles across different stages of life are not well understood. Animal studies can offer useful insights. OBJECTIVE: The goal of this study was to determine the impact of early life exposure to traumatic events on behavioral and cognitive profile in rats by tracking the behavior of each rat at different ages...
August 1, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28433469/delayed-effect-of-early-life-corticosterone-treatment-on-adult-anti-predator-behavior-in-a-common-passerine
#8
Jacquelyn K Grace, Laure Martin-Gousset, Frédéric Angelier
Acute, short-term effects of early-life stress and associated glucocorticoid upregulation on behavior are widely documented across vertebrates. However, the persistence and severity of these effects are largely unknown, especially through the adult stage and in wild species. Here, we investigate long-term effects of experimental post-natal increases in a circulating glucocorticoid on antipredator behavior in wild house sparrows (Passer domesticus) tested in captivity. We manipulate circulating corticosterone concentration in wild, free-living nestlings, transfer fledglings to captivity, and test juveniles and adults for two measures of antipredator behavior: evasiveness during a direct human encounter, and propensity to escape from a risky environment...
April 19, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28377702/brain-acetaldehyde-exposure-impacts-upon-neonatal-respiratory-plasticity-and-ethanol-related-learning-in-rodents
#9
María B Acevedo, Génesis D'Aloisio, Olga B Haymal, Juan C Molina
Prior studies indicate that neonates are very sensitive to ethanol's positive reinforcing effects and to its depressant effects upon breathing. Acetaldehyde (ACD) appears to play a major role in terms of modulating early reinforcing effects of the drug. Yet, there is no pre-existing literature relative to the incidence of this metabolite upon respiratory plasticity. The present study analyzed physiological and behavioral effects of early central administrations of ethanol, acetaldehyde or vehicle. Respiration rates (breaths/min) were registered at post-natal days (PDs) 2 and 4 (post-administration time: 5, 60, or 120 min)...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28377259/effects-of-social-deprivation-on-social-and-depressive-like-behaviors-and-the-numbers-of-oxytocin-expressing-neurons-in-rats
#10
Yaminah D Gilles, Eva K Polston
Social isolation is a known stressor that negatively impacts the well-being of social species. In rodents, social deprivation experienced either before or after weaning profoundly impacts adult behavioral and neuroendocrine profiles. This study compared the effects of post-natal and post-weaning social deprivation on behavioral profiles and hypothalamic oxytocin (OT) neurons. Male and female Sprague-Dawley rats were assigned to two post-natal groups, maternally separated (MS) or non-MS. MS pups were separated from their mothers for 4h daily during post-natal days 2-21 while non-MS litters remained undisturbed...
June 15, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28355286/gender-preference-and-perinatal-depression-in-turkey-a-cohort-study
#11
Vesile Senturk Cankorur, Berker Duman, Clare Taylor, Robert Stewart
BACKGROUND: Child gender preference is important in some cultures and has been found to modify risk for antenatal and postnatal depression. We investigated discrepancies in the child gender preference between participating women and other key family members and the extent to which these predicted perinatal depression. METHODS: In a large cohort study of perinatal depression in urban and rural Turkey, participants had been asked about child gender preferences: their own, and those of their husband, parents, and parents in-law...
2017: PloS One
https://www.readbyqxmd.com/read/28284344/are-there-early-inflammatory-biomarkers-that-affect-neurodevelopment-in-infancy
#12
Núria Voltas, Victoria Arija, Carmen Hernández-Martínez, Rosa Jiménez-Feijoo, Natàlia Ferré, Josefa Canals
Few studies have investigated the relationship between post-natal inflammatory biomarkers at early age and child neurodevelopment outcomes. The main aim of this study was to examine the relationship between IL-6, IL-1β, IL-4 cytokines, as well as cortisol at 6 and 12months of age, and neurodevelopment and psychological problems at 30months of age. The study was conducted on a sample of 51 full-term newborns who were followed up at 6, 12, and 30months of age. Infant neurodevelopment was assessed using the Bayley Scales of Infant Development-II, psychological problems were assessed with the Child Behavior Checklist 1...
April 15, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28218994/maternal-stress-and-psychological-distress-preconception-association-with-offspring-atopic-eczema-at-age-12-months
#13
S El-Heis, S R Crozier, E Healy, S M Robinson, N C Harvey, C Cooper, H M Inskip, J Baird, K M Godfrey
BACKGROUND: Perinatal maternal stress and low mood have been linked to offspring atopic eczema. OBJECTIVES: To examine the relation of maternal stress/mood with atopic eczema in the offspring, focusing particularly on stress/psychological distress preconception. METHODS: At recruitment in the UK Southampton Women's Survey, preconception maternal reports of perceived stress in daily living and the effect of stress on health were recorded; in a subsample, psychological distress was assessed (12-item General Health Questionnaire)...
June 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28130185/chlorpyrifos-induces-anxiety-like-behavior-in-offspring-rats-exposed-during-pregnancy
#14
Jonas G Silva, Ana C Boareto, Anne K Schreiber, Daiany D B Redivo, Eder Gambeta, Fernanda Vergara, Helen Morais, Janaína M Zanoveli, Paulo R Dalsenter
Chlorpyrifos is a pesticide, member of the organophosphate class, widely used in several countries to manage insect pests on many agricultural crops. Currently, chlorpyrifos health risks are being reevaluated due to possible adverse effects, especially on the central nervous system. The aim of this study was to investigate the possible action of this pesticide on the behaviors related to anxiety and depression of offspring rats exposed during pregnancy. Wistar rats were treated orally with chlorpyrifos (0.01, 0...
January 24, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28114775/risk-factors-for-ptsd-and-depression-in-female-survivors-of-rape
#15
Nolwandle Mgoqi-Mbalo, Muyu Zhang, Sam Ntuli
OBJECTIVE: To investigate association of the sociodemographic factors, characteristics of rape and social support to the development of depression and posttraumatic stress disorder at 6 months after the rape. METHOD: A cross-sectional survey with female survivors of rape was carried out in 3 provinces of South Africa 6 months after the rape. RESULTS: One hundred female survivors s of sexual assault were interviewed. More than half (53%) were from Limpopo, 25% from Western Cape, and 22% from KwaZulu-Natal (KZN)...
May 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28094283/adolescent-chronic-unpredictable-stress-exposure-is-a-sensitive-window-for-long-term-changes-in-adult-behavior-in-mice
#16
Nicole L Yohn, Julie A Blendy
Adolescence is a time period in development when the brain undergoes substantial remodeling in response to the environment. To determine whether a stressful experience during adolescence affects adult behavior, we exposed adolescent male and female C57BL/6J mice to chronic unpredictable stress (CUS) for 12 days starting at postnatal day 28 (PND28). We also exposed adult male and female mice to CUS for 12 days beginning at PND70 to determine whether adolescence is a sensitive time period when stress can have long-lasting effects on behavior...
July 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28065954/postpartum-depression-and-associated-factors-after-emergency-peripartum-hysterectomy
#17
Mehmet Baki Senturk, Yusuf Cakmak, Ahmet Ozalp
OBJECTIVE: To investigate post-partum depression after emergency peripartum hysterectomy and associated factors. METHODS: This cross-sectional controlled study was conducted at Batman Gynaecology and Paediatric Diseases Hospital, Batman, Turkey, between June 15 and July 23, 2015, and comprised cases of patients with peripartum hysterectomy and of those who had experienced surgical procedures other than hysterectomy (hypogastric artery ligation and/or B-Lynch suture)...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27831486/ontogeny-of-norepinephrine-transporter-expression-and-antidepressant-like-response-to-desipramine-in-wild-type-and-serotonin-transporter-mutant-mice
#18
Nathan C Mitchell, Melodi A Bowman, Georgianna G Gould, Wouter Koek, Lynette C Daws
Depression is a major public health concern with symptoms that are often poorly controlled by treatment with common antidepressants. This problem is compounded in juveniles and adolescents, because therapeutic options are limited to selective serotonin reuptake inhibitors (SSRIs). Moreover, therapeutic benefits of SSRIs are often especially limited in certain subpopulations of depressed patients, including children and carriers of low-expressing serotonin transporter (SERT) gene variants. Tricyclic antidepressants (TCAs) offer an alternative to SSRIs; however, how age and SERT expression influence antidepressant response to TCAs is not understood...
January 2017: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/27814521/the-central-nervous-system-and-the-gut-microbiome
#19
REVIEW
Gil Sharon, Timothy R Sampson, Daniel H Geschwind, Sarkis K Mazmanian
Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals. While historically studied by researching the brain, inputs from the periphery impact many neurological conditions. Indeed, emerging data suggest communication between the gut and the brain in anxiety, depression, cognition, and autism spectrum disorder (ASD). The development of a healthy, functional brain depends on key pre- and post-natal events that integrate environmental cues, such as molecular signals from the gut...
November 3, 2016: Cell
https://www.readbyqxmd.com/read/27756349/depression-an-exploratory-parallel-group-randomised-controlled-trial-of-antenatal-guided-self-help-for-women-dawn-study-protocol-for-a-randomised-controlled-trial
#20
Kylee Trevillion, Jill Domoney, Andrew Pickles, Debra Bick, Sarah Byford, Margaret Heslin, Jeannette Milgrom, Rachel Mycroft, Carmine Pariante, Elizabeth Ryan, Myra Hunter, Louise Michele Howard
BACKGROUND: Depression is a common antenatal mental disorder and is associated with an increased risk of adverse effects on the fetus and significant morbidity for the mother; if untreated it can also continue into the post-natal period and affect mother-infant interactions. There has been little research evaluating the effectiveness or cost-effectiveness of antenatal psychological interventions for antenatal depression, particularly for mild to moderate disorders. International guidelines recommend a stepped care approach starting with Guided Self Help, and the aim of this exploratory trial is to investigate Guided Self Help modified for pregnancy...
October 18, 2016: Trials
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