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Post natal depression

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https://www.readbyqxmd.com/read/28527907/behavioral-and-cognitive-impact-of-early-life-stress-insights-from-an-animal-model
#1
Hesong Liu, Fatin Atrooz, Ankita Salvi, Samina Salim
BACKGROUND: Children subjected to traumatic events during childhood are reported to exhibit behavioral and cognitive deficits later in life, often leading to post-traumatic stress disorder (PTSD) and major depression. Interestingly, some children continue to remain normal despite being exposed to the same risk factors. These trauma-related behavioral and cognitive profiles across different stages of life are not well understood. Animal studies can offer useful insights. OBJECTIVE: The goal of this study was to determine the impact of early life exposure to traumatic events on behavioral and cognitive profile in rats by tracking the behavior of each rat at different ages...
May 17, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28433469/delayed-effect-of-early-life-corticosterone-treatment-on-adult-anti-predator-behavior-in-a-common-passerine
#2
Jacquelyn K Grace, Laure Martin-Gousset, Frédéric Angelier
Acute, short-term effects of early-life stress and associated glucocorticoid upregulation on behavior are widely documented across vertebrates. However, the persistence and severity of these effects are largely unknown, especially through the adult stage and in wild species. Here, we investigate long-term effects of experimental post-natal increases in a circulating glucocorticoid on antipredator behavior in wild house sparrows (Passer domesticus) tested in captivity. We manipulate circulating corticosterone concentration in wild, free-living nestlings, transfer fledglings to captivity, and test juveniles and adults for two measures of antipredator behavior: evasiveness during a direct human encounter, and propensity to escape from a risky environment...
April 19, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28377702/brain-acetaldehyde-exposure-impacts-upon-neonatal-respiratory-plasticity-and-ethanol-related-learning-in-rodents
#3
María B Acevedo, Génesis D'Aloisio, Olga B Haymal, Juan C Molina
Prior studies indicate that neonates are very sensitive to ethanol's positive reinforcing effects and to its depressant effects upon breathing. Acetaldehyde (ACD) appears to play a major role in terms of modulating early reinforcing effects of the drug. Yet, there is no pre-existing literature relative to the incidence of this metabolite upon respiratory plasticity. The present study analyzed physiological and behavioral effects of early central administrations of ethanol, acetaldehyde or vehicle. Respiration rates (breaths/min) were registered at post-natal days (PDs) 2 and 4 (post-administration time: 5, 60, or 120 min)...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28377259/effects-of-social-deprivation-on-social-and-depressive-like-behaviors-and-the-numbers-of-oxytocin-expressing-neurons-in-rats
#4
Yaminah D Gilles, Eva K Polston
Social isolation is a known stressor that negatively impacts the well-being of social species. In rodents, social deprivation experienced either before or after weaning profoundly impacts adult behavioral and neuroendocrine profiles. This study compared the effects of post-natal and post-weaning social deprivation on behavioral profiles and hypothalamic oxytocin (OT) neurons. Male and female Sprague-Dawley rats were assigned to two post-natal groups, maternally separated (MS) or non-MS. MS pups were separated from their mothers for 4h daily during post-natal days 2-21 while non-MS litters remained undisturbed...
April 1, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28355286/gender-preference-and-perinatal-depression-in-turkey-a-cohort-study
#5
Vesile Senturk Cankorur, Berker Duman, Clare Taylor, Robert Stewart
BACKGROUND: Child gender preference is important in some cultures and has been found to modify risk for antenatal and postnatal depression. We investigated discrepancies in the child gender preference between participating women and other key family members and the extent to which these predicted perinatal depression. METHODS: In a large cohort study of perinatal depression in urban and rural Turkey, participants had been asked about child gender preferences: their own, and those of their husband, parents, and parents in-law...
2017: PloS One
https://www.readbyqxmd.com/read/28284344/are-there-early-inflammatory-biomarkers-that-affect-neurodevelopment-in-infancy
#6
Núria Voltas, Victoria Arija, Carmen Hernández-Martínez, Rosa Jiménez-Feijoo, Natàlia Ferré, Josefa Canals
Few studies have investigated the relationship between post-natal inflammatory biomarkers at early age and child neurodevelopment outcomes. The main aim of this study was to examine the relationship between IL-6, IL-1β, IL-4 cytokines, as well as cortisol at 6 and 12months of age, and neurodevelopment and psychological problems at 30months of age. The study was conducted on a sample of 51 full-term newborns who were followed up at 6, 12, and 30months of age. Infant neurodevelopment was assessed using the Bayley Scales of Infant Development-II, psychological problems were assessed with the Child Behavior Checklist 1...
April 15, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28218994/maternal-stress-and-psychological-distress-preconception-association-with-offspring-atopic-eczema-at-age-12-months
#7
S El-Heis, S R Crozier, E Healy, S M Robinson, N C Harvey, C Cooper, H M Inskip, J Baird, K M Godfrey
BACKGROUND: Perinatal maternal stress and low mood have been linked to offspring atopic eczema. OBJECTIVES: To examine the relation of maternal stress/mood with atopic eczema in the offspring, focusing particularly on stress/psychological distress preconception. METHODS: At recruitment in the UK Southampton Women's Survey, preconception maternal reports of perceived stress in daily living and the effect of stress on health were recorded; in a subsample, psychological distress was assessed (12-item General Health Questionnaire)...
February 20, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28130185/chlorpyrifos-induces-anxiety-like-behavior-in-offspring-rats-exposed-during-pregnancy
#8
Jonas G Silva, Ana C Boareto, Anne K Schreiber, Daiany D B Redivo, Eder Gambeta, Fernanda Vergara, Helen Morais, Janaína M Zanoveli, Paulo R Dalsenter
Chlorpyrifos is a pesticide, member of the organophosphate class, widely used in several countries to manage insect pests on many agricultural crops. Currently, chlorpyrifos health risks are being reevaluated due to possible adverse effects, especially on the central nervous system. The aim of this study was to investigate the possible action of this pesticide on the behaviors related to anxiety and depression of offspring rats exposed during pregnancy. Wistar rats were treated orally with chlorpyrifos (0.01, 0...
January 24, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28114775/risk-factors-for-ptsd-and-depression-in-female-survivors-of-rape
#9
Nolwandle Mgoqi-Mbalo, Muyu Zhang, Sam Ntuli
OBJECTIVE: To investigate association of the sociodemographic factors, characteristics of rape and social support to the development of depression and posttraumatic stress disorder at 6 months after the rape. METHOD: A cross-sectional survey with female survivors of rape was carried out in 3 provinces of South Africa 6 months after the rape. RESULTS: One hundred female survivors s of sexual assault were interviewed. More than half (53%) were from Limpopo, 25% from Western Cape, and 22% from KwaZulu-Natal (KZN)...
May 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28094283/adolescent-chronic-unpredictable-stress-exposure-is-a-sensitive-window-for-long-term-changes-in-adult-behavior-in-mice
#10
Nicole L Yohn, Julie A Blendy
Adolescence is a time period in development when the brain undergoes substantial remodeling in response to the environment. To determine whether a stressful experience during adolescence affects adult behavior, we exposed adolescent male and female C57BL/6J mice to chronic unpredictable stress (CUS) for 12 days starting at postnatal day 28 (PND28). We also exposed adult male and female mice to CUS for 12 days beginning at PND70 to determine whether adolescence is a sensitive time period when stress can have long-lasting effects on behavior...
February 1, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28065954/postpartum-depression-and-associated-factors-after-emergency-peripartum-hysterectomy
#11
Mehmet Baki Senturk, Yusuf Cakmak, Ahmet Ozalp
OBJECTIVE: To investigate post-partum depression after emergency peripartum hysterectomy and associated factors. METHODS: This cross-sectional controlled study was conducted at Batman Gynaecology and Paediatric Diseases Hospital, Batman, Turkey, between June 15 and July 23, 2015, and comprised cases of patients with peripartum hysterectomy and of those who had experienced surgical procedures other than hysterectomy (hypogastric artery ligation and/or B-Lynch suture)...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27831486/ontogeny-of-norepinephrine-transporter-expression-and-antidepressant-like-response-to-desipramine-in-wild-type-and-serotonin-transporter-mutant-mice
#12
Nathan C Mitchell, Melodi A Bowman, Georgianna G Gould, Wouter Koek, Lynette C Daws
Depression is a major public health concern with symptoms that are often poorly controlled by treatment with common antidepressants. This problem is compounded in juveniles and adolescents, because therapeutic options are limited to selective serotonin reuptake inhibitors (SSRIs). Moreover, therapeutic benefits of SSRIs are often especially limited in certain subpopulations of depressed patients, including children and carriers of low-expressing serotonin transporter (SERT) gene variants. Tricyclic antidepressants (TCAs) offer an alternative to SSRIs; however, how age and SERT expression influence antidepressant response to TCAs is not understood...
January 2017: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/27814521/the-central-nervous-system-and-the-gut-microbiome
#13
REVIEW
Gil Sharon, Timothy R Sampson, Daniel H Geschwind, Sarkis K Mazmanian
Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals. While historically studied by researching the brain, inputs from the periphery impact many neurological conditions. Indeed, emerging data suggest communication between the gut and the brain in anxiety, depression, cognition, and autism spectrum disorder (ASD). The development of a healthy, functional brain depends on key pre- and post-natal events that integrate environmental cues, such as molecular signals from the gut...
November 3, 2016: Cell
https://www.readbyqxmd.com/read/27756349/depression-an-exploratory-parallel-group-randomised-controlled-trial-of-antenatal-guided-self-help-for-women-dawn-study-protocol-for-a-randomised-controlled-trial
#14
Kylee Trevillion, Jill Domoney, Andrew Pickles, Debra Bick, Sarah Byford, Margaret Heslin, Jeannette Milgrom, Rachel Mycroft, Carmine Pariante, Elizabeth Ryan, Myra Hunter, Louise Michele Howard
BACKGROUND: Depression is a common antenatal mental disorder and is associated with an increased risk of adverse effects on the fetus and significant morbidity for the mother; if untreated it can also continue into the post-natal period and affect mother-infant interactions. There has been little research evaluating the effectiveness or cost-effectiveness of antenatal psychological interventions for antenatal depression, particularly for mild to moderate disorders. International guidelines recommend a stepped care approach starting with Guided Self Help, and the aim of this exploratory trial is to investigate Guided Self Help modified for pregnancy...
October 18, 2016: Trials
https://www.readbyqxmd.com/read/27660558/recognition-and-management-of-perinatal-depression-and-anxiety-by-general-practitioners-a-systematic-review
#15
REVIEW
Elizabeth Ford, Judy Shakespeare, Fatin Elias, Susan Ayers
BACKGROUND: Perinatal anxiety and depression are widespread, with up to 20% of women affected during pregnancy and after birth. In the UK, management of perinatal mental health falls under the remit of general practitioners (GPs). We reviewed the literature on GPs' routine recognition, diagnosis and management of anxiety and depression in the perinatal period. METHOD: A systematic search of Embase, Medline, PsycInfo, Pubmed, Scopus and Web of Science was conducted...
September 22, 2016: Family Practice
https://www.readbyqxmd.com/read/27658457/the-association-between-maternal-and-partner-experienced-racial-discrimination-and-prenatal-perceived-stress-prenatal-and-postnatal-depression-findings-from-the-growing-up-in-new-zealand-cohort-study
#16
Laia Bécares, Polly Atatoa-Carr
BACKGROUND: A growing number of studies document the association between maternal experiences of racial discrimination and adverse children's outcomes, but our understanding of how experiences of racial discrimination are associated with pre- and post-natal maternal mental health, is limited. In addition, existent literature rarely takes into consideration racial discrimination experienced by the partner. METHODS: We analysed data from the Growing Up in New Zealand study to examine the burden of lifetime and past year experiences of racial discrimination on prenatal and postnatal mental health among Māori, Pacific, and Asian women in New Zealand (NZ), and to study the individual and joint contribution of mother's and partner's experiences of lifetime and past year racial discrimination to women's prenatal and postnatal mental health...
September 22, 2016: International Journal for Equity in Health
https://www.readbyqxmd.com/read/27561997/mothers-perinatal-and-infant-mental-health-knowledge-in-a-johannesburg-township-setting
#17
Katherine Bain, Jade Richards
OBJECTIVE: This paper examines maternal knowledge regarding perinatal and infant mental health amongst mothers in Alexandra township, Johannesburg. The applicability and utility of these Western-derived concepts in a low socio-economic South African setting is examined. METHOD: A concurrent mixed methods approach was used. Descriptive statistical analysis was conducted on the responses of 255 mothers on a structured questionnaire, designed to elicit levels of knowledge about the relational needs and awareness of infants and the psychosocial needs of mothers, to determine trends in mothers' knowledge...
July 2016: Journal of Child and Adolescent Mental Health
https://www.readbyqxmd.com/read/27518778/the-challenges-of-a-successful-pregnancy-in-a-patient-with-adult-refsum-s-disease-due-to-phytanoyl-coa-hydroxylase-deficiency
#18
Karolina M Stepien, Anthony S Wierzbicki, Bwee T Poll-The, Hans R Waterham, Christian J Hendriksz
We describe the management and outcomes of pregnancy in a 27-year-old woman with infantile-onset Adult Refsum's disease (ARD). She presented in infancy but was diagnosed with ARD at the age of 10 on basis of phytanic acidaemia and later confirmed to have the phytanoyl-CoA hydroxylase ((PHYH) c.164delT, p.L55fsX12) mutation. Despite repeated plasmapheresis sessions and strict dietary surveillance for 20 years, her phytanic acid levels persistently stayed above the ideal target level of 100 μmol/L but remained below 400 μmol/L...
2017: JIMD Reports
https://www.readbyqxmd.com/read/27338722/posttraumatic-stress-disorder-following-stillbirth-trauma-characteristics-locus-of-control-posttraumatic-cognitions
#19
Man Cheung Chung, Jacqueline Reed
This study examined the incidence of PTSD and psychiatric co-morbidity among women who experienced stillbirth and investigated the relationship between locus of control, trauma characteristics of stillbirth, posttraumatic cognitions, PTSD and co-morbid psychiatric symptoms following stillbirth. Fifty women recorded information on stillbirth experiences, and completed the Posttraumatic Stress Diagnostic Scale, General Health Questionnaire-28, Edinburgh Post-natal Depression Scale, Rotter's Locus of Control Scale and the Posttraumatic Cognitions Inventory...
June 23, 2016: Psychiatric Quarterly
https://www.readbyqxmd.com/read/27209204/molecular-and-behavioral-profiling-of-dbx1-derived-neurons-in-the-arcuate-lateral-and-ventromedial-hypothalamic-nuclei
#20
Katie Sokolowski, Tuyen Tran, Shigeyuki Esumi, Yasmin Kamal, Livio Oboti, Julieta Lischinsky, Meredith Goodrich, Andrew Lam, Margaret Carter, Yasushi Nakagawa, Joshua G Corbin
BACKGROUND: Neurons in the hypothalamus function to regulate the state of the animal during both learned and innate behaviors, and alterations in hypothalamic development may contribute to pathological conditions such as anxiety, depression or obesity. Despite many studies of hypothalamic development and function, the link between embryonic development and innate behaviors remains unexplored. Here, focusing on the embryonically expressed homeodomain-containing gene Developing Brain Homeobox 1 (Dbx1), we explored the relationship between embryonic lineage, post-natal neuronal identity and lineage-specific responses to innate cues...
2016: Neural Development
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