Ahmed O Abdelaty, Engy K Tharwat, Alaa I Abdelrahman, Ayatallah Elgohary, Hebatallah Elsaeed, Amena S El-Feky, Yasmina M Ebrahim, Abdelaziz Habib, Hasnaa Abd El Latif, Yasser A Khadrawy, Heba S Aboul Ezz, Neveen A Noor, Heba M Fahmy, Faten F Mohammed, Nasr M Radwan, Nawal A Ahmed
RATIONALE: Depression is the most prevalent psychiatric disorder worldwide. Although numerous antidepressant treatments are available, there is a serious clinical concern due to their severe side effects and the fact that some depressed patients are resistant to them. Lithium is the drug of choice for bipolar depression and has been used as adjunct therapy with other groups of antidepressants. OBJECTIVES: The present study aims to investigate the effect of lithium augmentation with cerebrolysin on the neurochemical, behavioral and histopathological alterations induced in the reserpine model of depression...
February 17, 2024: Journal of Psychiatric Research