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https://www.readbyqxmd.com/read/28817155/genetic-variation-of-15-autosomal-strs-in-a-population-sample-of-bedouins-residing-in-the-area-of-the-fourth-nile-cataract-sudan
#1
Andrzej Ossowski, Jaroslaw Piatek, Miroslaw Parafiniuk, Aleksandra Pudlo, Witold Pepinski, Malgorzata Skawronska, Michal Szeremeta, Anna Niemcunowicz-Janica, Ireneusz Soltyszewski
The purpose of the paper was to report allelic frequencies of 15 autosomal STR markers (AmpFlSTR NGM PCR Amplification Kit) for Bedouin inhabitants in the area of the Fourth Nile Cataract in Sudan, and compute commonly used population and forensic biostatistical parameters. Buccal swabs were collected from 117 unrelated individuals. DNA was extracted using DNA QIAamp(®) DNA Mini Kit, and quantitated with Quantifiler Human Quantification Kit in a 7500 Real-Time PCR System. Amplification of 15 AmpFlSTR NGM PCR Kit loci was performed in PCR System 9700...
August 17, 2017: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
https://www.readbyqxmd.com/read/28815945/development-of-a-quantitative-method-for-the-analysis-of-cocaine-analogue-impregnated-into-textiles-by-raman-spectroscopy
#2
Linda Xiao, Rhiannon Alder, Megha Mehta, Nadine Krayem, Bianca Cavasinni, Sean Laracy, Shane Cameron, Shanlin Fu
Cocaine trafficking in the form of textile impregnation is routinely encountered as a concealment method. Raman spectroscopy has been a popular and successful testing method used for in situ screening of cocaine in textiles and other matrices. Quantitative analysis of cocaine in these matrices using Raman spectroscopy has not been reported to date. This study aimed to develop a simple Raman method for quantifying cocaine using atropine as the model analogue in various types of textiles. Textiles were impregnated with solutions of atropine in methanol...
August 16, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28815938/optimization-of-recombinant-%C3%AE-glucuronidase-hydrolysis-and-quantification-of-eight-urinary-cannabinoids-and-metabolites-by-liquid-chromatography-tandem-mass-spectrometry
#3
Cristina Sempio, Karl B Scheidweiler, Allan J Barnes, Marilyn A Huestis
Prolonged urinary cannabinoid excretion in chronic frequent cannabis users confounds identification of recent cannabis intake that may be important in treatment, workplace, clinical, and forensic testing programs. In addition, differentiation of synthetic Δ9-tetrahydrocannabinol (THC) intake from cannabis plant products might be an important interpretive issue. THC, 11-hydroxy-THC (11-OH-THC) and 11-nor-9-carboxy-THC (THCCOOH) urine concentrations were evaluated during previous controlled cannabis administration studies following tandem alkaline/E...
June 14, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28815699/application-of-the-condensed-protocol-for-the-nia-aa-guidelines-for-the-neuropathologic-assessment-of-alzheimer-s-disease-in-an-academic-clinical-practice
#4
Rajnish Bharadwaj, Patrick J Cimino, Margaret E Flanagan, Caitlin S Latimer, Luis F Gonzalez-Cuyar, Gordana Juric-Sekhar, Thomas J Montine, Desiree A Marshall, C Dirk Keene
AIMS: In response to concerns regarding resource expenditures required to fully implement the 2012 NIA-AA Sponsored Guidelines for the neuropathologic assessment of Alzheimer's disease (AD), we previously developed a sensitive and cost-reducing Condensed Protocol (CP) at the University of Washington (UW) Alzheimer's Disease Research Center (ADRC) that consolidated the recommended NIA-AA protocol into fewer cassettes requiring fewer immunohistochemical stains. The CP was not designed to replace NIA-AA protocols, but instead to make the NIA-AA criteria accessible to clinical and forensic neuropathology practices where resources limit full implementation of NIA-AA guidelines...
August 16, 2017: Histopathology
https://www.readbyqxmd.com/read/28812137/myoglobinemia-markers-with-potential-applications-in-forensic-sample-analysis-lipid-markers-in-myoglobinemia-for-postmortem-blood
#5
Hiroko Abe, Daisuke Yajima, Yumi Hoshioka, Akina Nara, Sayaka Nagasawa, Hirotaro Iwase
The crush syndrome, in which rhabdomyolysis and trauma occur as a result of heat stroke and drug intoxication, can lead to myoglobinemia. This condition can be diagnosed by measuring myoglobin (Mb) levels in blood and urine. However, postmortem Mb levels are unreliable indicators, since blood Mb concentration drastically increases within a very short time after death and urine cannot always be obtained at dissection; this makes it difficult to diagnose myoglobinemia in a corpse. To address this issue, in this study, we used a lipidomics approach to identify markers that can be used to detect myoglobinemia in postmortem blood samples...
August 15, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28811914/the-impact-of-transforming-care-on-the-care-and-safety-of-patients-with-intellectual-disabilities-and-forensic-needs
#6
John L Taylor, Iain McKinnon, Ian Thorpe, Bruce T Gillmer
NHS England recently published a national plan to develop community services for people with intellectual disabilities and autism who display challenging behaviour by using resources from the closure of a large number of hospital beds. An ambitious timescale has been set to implement this plan. The bed closure programme is moving ahead rapidly, but there has been little progress in developing community services to support it. This paper discusses the impact of the gap between policy and practice on the care and safety of patients with intellectual disabilities and forensic needs who form a distinct subgroup of the target population and are being disproportionately affected by this government policy...
August 2017: BJPsych Bulletin
https://www.readbyqxmd.com/read/28810732/tracking-radionuclide-fractionation-in-the-first-atomic-explosion-using-stable-elements
#7
Chloe E Bonamici, Richard L Hervig, William S Kinman
Compositional analysis of post-detonation fallout is a tool for forensic identification of nuclear devices. However, the relationship between device composition and fallout composition is difficult to interpret because of the complex combination of physical mixing, nuclear reactions, and chemical fractionations that occur in the chaotic nuclear fireball. Using a combination of in situ microanalytical techniques - electron microprobe analysis and secondary ion mass spectrometry - we show that some heavy stable elements (Rb, Sr, Zr, Ba, Cs, Ba, La, Ce, Nd, Sm, Dy, Lu, U, Th) in glassy fallout from the first nuclear test, Trinity, are reliable chemical proxies for radionuclides generated during the explosion...
August 16, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28810161/ethical-considerations-for-forensic-scientists-participating-in-humanitarian-action-a-personal-reflection
#8
Jørgen L Thomsen
Humanitarian Forensic Action is aimed at relieving suffering by comforting and informing the relatives of disaster victims. It is not a priority to report human rights abuses to the authorities. It is thereby different from forensic human rights work with an inquisitive way of demonstrating culpability. The following tasks are relevant. The forensic scientist as an interviewer of the next of kin and witnesses. Emphasizing independency in armed conflicts. Assisting in man-made and natural disasters Assisting in the prevention and of the spread of epidemics...
July 29, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28810073/implications-of-pseudologia-fantastica-in-criminal-forensic-evaluations-a-review-and-case-report
#9
Richard L Frierson, Kaustubh G Joshi
Pseudologia fantastica, a psychological phenomenon that has been described in the literature for at least a century, is an understudied and poorly understood entity. Sometimes referred to as pathological lying, pseudologia fantastica involves disproportionate fabrication that may be present for many years or a lifetime. In a forensic context, it can significantly complicate the evaluation of capacity to stand trial and, in certain jurisdictions, criminal responsibility. We review the current literature regarding pseudologia fantastica and present a case to highlight the clinical and forensic challenges it may create...
August 15, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28810069/homicide-rates-in-lithuania
#10
Sigitas Chmieliauskas, Sigitas Laima, Gerda Andriuskeviciute, Eleonora Jurolaic, Algimantas Jasulaitis
Homicide rate in Lithuania between 2004 and 2013 decreased and reached an average of 6.7 per 100,000 people in 2013. The data regarding forensic autopsies of intentional homicide victims were obtained from the State Forensic Medicine Service. Spearman's correlation test was used to assess trends in the homicide rates. A significant correlation was observed between homicide distribution and the following variables: Lithuania's gross domestic product (r = -0.85, p = 0.003), the number of alcohol intoxication cases of victims (r = 0...
August 15, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28810068/putrefaction-an-additional-complicating-factor-in-the-assessment-of-freshwater-drownings-in-rivers
#11
Roger W Byard
Background hypothesis: That bodies immersed in freshwater (rivers) may show greater changes of decomposition than bodies immersed in saltwater (sea). Fifty de-identified river drownings and 50 sea drownings were randomly selected from autopsy files at Forensic Science SA, Adelaide, Australia and assessed for decomposition. RESULTS: The river cases consisted of 43 males and seven females (M:F 6:1); age range of 2-92 years (mean 46.8 years); decomposition-16/50 (32%); postmortem interval 1-14 days, average 3...
August 15, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28809481/spectral-mining-for-discriminating-blood-origins-in-the-presence-of-substrate-interference-via-atr-ft-ir-postmortem-or-antemortem-blood
#12
Ayari Takamura, Ken Watanabe, Tomoko Akutsu, Hiroshi Ikegaya, Takeaki Ozawa
Often in criminal investigations, discrimination of types of body fluid evidence is crucially important to ascertain how a crime was committed. Compared to current methods using biochemical techniques, vibrational spectroscopic approaches can provide versatile applicability to identify various body fluid types without sample invasion. However, their applicability is limited to pure body fluid samples because important signals from body fluids incorporated in a substrate are affected strongly by interference from substrate signals...
August 15, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28807464/sex-estimation-using-dimensions-around-the-nutrient-foramen-of-the-long-bones-of-the-arm-and-forearm-in-south-africans
#13
Palesa Mokoena, Brendon K Billings, Mubarak A Bidmos, Pedzisai Mazengenya
South Africa has had an increase in rates of crime, interpersonal violence and homicide since the introduction of democracy in 1994. Forensic osteological standards was lacking for South Africans of different population groups necessitating the generation of new standards for forensic identification of individuals from skeletal remains. For these reasons, there is a concerted demand for methods of identifying skeletal remains with sex being amongst the most important of the biological characteristics required...
July 10, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28806859/analysis-of-low-molecular-weight-compounds-using-maldi-and-ldi-tof-ms-direct-detection-of-active-pharmaceutical-ingredients-in-different-formulations
#14
João L Bronzel, Cintia D F Milagre, Humberto M S Milagre
Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry (MALDI-MS) is a high throughput, easy to use analytical technique. The simple sample preparation of this technique and its tolerance to the presence of contaminants are among its advantages. In contrast, depending on the matrix used, MALDI can ionize and generates ions in the low m/z range that complicate the interpretation of the spectra of low molecular weight compounds. To address this issue, one can envisage the use of tunable ionic matrices that can reduce the low m/z interferents...
August 14, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28806825/-completeness-and-reproducibility-of-surgical-reports-a%C3%A2-retrospective-analysis-of-documentation-quality-using-the-example-of-dupuytren-s-disease
#15
Elisabeth Russe, Andrea Wenger, Gottfried Wechselberger, Hildegunde Piza-Katzer
Background A surgical report is the surgeon's postoperative documentation of the procedure undertaken. The purpose of this study was to evaluate the completeness and accuracy of data extracted from surgical reports, using the example of Dupuytren's disease. Material and Methods Between 1999 and 2007, surgical data were retrospectively collected from all primary Dupuytren's disease procedures performed at an academic department for plastic and reconstructive surgery and analysed for completeness. A surgical report was assessed as complete if data on indication, affected side and finger(s), tourniquet, type of incision and surgical procedure were stated...
August 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28806636/blood-or-not-blood-that-is-the-question-a-non-destructive-method-for-the-detection-of-blood-contaminated-fingermarks
#16
Alfonso Bentolila, Ira Hartman, Michal Levin-Elad
Working in crime scenes presents a challenge to the forensic scientist, as some surfaces, such as floors and walls, cannot be transferred to the lab for further development and must, therefore, be processed at the crime scene itself. Two main types of latent fingermarks may be encountered in crime scenes: amino acids based and blood contaminated. One of the most common reagents, which are able to develop both types of fingermarks on porous surfaces, is ninhydrin. As blood contaminated fingermarks may be crucial in connecting the suspect to the crime it is important to be able to distinguish between them and natural fingermarks...
August 5, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28806630/case-report-coincidental-inclusion-in-a-17-locus-y-str-mixture-wrongful-conviction-and-exoneration
#17
Greg Hampikian, Gianluca Peri, Shih-Shiang Lo, Mong-Hwa Chin, Kuo-Lan Liu
We report the case of a suspect (Suspect-3) who was convicted (and later exonerated) of participating in the multiple-attacker rape of two women. The forensic evidence against him was his inclusion in a 17-marker Y-STR mixture isolated from semen on one victim's clothing. The DNA inclusion produced a match statistic with a combined probability of inclusion of 1 in 741, and a Likelihood Ratio of 3296. While the defense team was told that Suspect-3 was included in the semen DNA mixture, they were not told that all of the Y-STR alleles could also be explained by just the other two accused attackers' haplotypes...
August 7, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28805487/state-of-the-art-nanopathological-diagnostics
#18
Luca Roncati, Giuseppe Barbolini
The nanopathological diagnostics (ND) is an ultra-specialized branch of pathological anatomy aimed to identify the nanoparticles of metallic, semimetallic, or nonmetallic elements in the inorganic particulate matter present inside pathological tissues, even on the nanometer scale. ND exploits an environmental scanning electron microscope, connected to an X-ray microprobe mounted on an energy-dispersive spectrometer. The searching of nanoparticles can be performed on paraffin-embedded material, omitting emissions of black overlay and plating procedures...
August 14, 2017: Ultrastructural Pathology
https://www.readbyqxmd.com/read/28804655/a-new-phase-for-egyptian-journal-of-forensic-sciences-the-official-journal-of-the-international-association-of-law-and-forensic-sciences-ialfs
#19
EDITORIAL
Magdy Kharoshah, Mohammed Madadin
No abstract text is available yet for this article.
2017: Egyptian journal of forensic sciences
https://www.readbyqxmd.com/read/28803722/advantages-of-analyzing-postmortem-brain-samples-in-routine-forensic-drug-screening-case-series-of-three-non-natural-deaths-tested-positive-for-lysergic-acid-diethylamide-lsd
#20
Marie Mardal, Sys Stybe Johansen, Ragnar Thomsen, Kristian Linnet
Three case reports are presented, including autopsy findings and toxicological screening results, which were tested positive for the potent hallucinogenic drug lysergic acid diethylamide (LSD). LSD and its main metabolites were quantified in brain tissue and femoral blood, and furthermore hematoma and urine when available. LSD, its main metabolite 2-oxo-3-hydroxy-LSD (oxo-HO-LSD), and iso-LSD were quantified in biological samples according to a previously published procedure involving liquid-liquid extraction and ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)...
July 30, 2017: Forensic Science International
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