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Álvaro Alarcón, Isabel Lagos, Alberto Fica
Pneumococcal infections are important for their morbidity and economic burden, but there is no economical data from adults patients in Chile. AIMS: Estimate direct medical costs of bacteremic pneumococcal pneumonia among adult patients hospitalized in a general hospital and to evaluate the sensitivity of ICD 10 discharge codes to capture infections from this pathogen. METHODS: Analysis of hospital charges by components in a group of patients admitted for bacteremic pneumococcal pneumonia, correction of values by inflation and conversion from CLP to US$...
August 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
Emilio Bouza, José Martínez-Alarcón, Emilio Maseda, Mercedes Palomar, Rafael Zaragoza, María Jesús Pérez-Granda, Patricia Muñoz, Almudena Burillo
INTRODUCTION: Current guidelines for the microbiological diagnosis of ventilator-associated pneumonia (VAP) are imprecise. Based on data provided by intensive care specialists (ICS) and microbiologists, this study defines the clinical practices and microbiological techniques currently used for an aetiological diagnosis of VAP and pinpoints deficiencies. METHODS: Eighty hospitals in the national health network with intensive care and microbiology departments were sent two questionnaires, one for each department, in order to collect data on VAP diagnosis for the previous year...
March 2017: Enfermedades Infecciosas y Microbiología Clínica
Olaia Martínez González, Itsaso Zabaleta Vélez de Mendizábal, Uxue Galarza Iriarte, María Soledad Vicente Martín, María Del Carmen De Vega Castaño, Jesús Salmerón Egea
No abstract text is available yet for this article.
March 25, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Seerangaraj Vijayaram, Suruli Kannan, Konda Mani Saravanan, Seerangaraj Vasantharaj, Selvam Sathiyavimal, Palanisamy Senthilkumar P
The presence study was aimed to catalyze the primary metabolites and their confirmation by using GC-MS analysis and antibacterial potential of leaf extract of two important medicinal plant viz., Eucalyptus and Azadirachta indica. The antibacterial potential of the methanol leaf extract of the studied species was tested against Escherichia coli, Pseudomonas aeruginosa, Klebsiellap neumoniae, Streptococcus pyogens, Staphylococcus aureus using by agar well diffusion method. The higher zone of inhibition (16mm) was observed against the bacterium Pseudomonas aeruginosa at 100μl concentration of methanol leaf extract...
May 2016: Pakistan Journal of Pharmaceutical Sciences
Antonio Heliodoro Chávez-Aguilar, Héctor Silva-Báez, Yamid Brajin Sánchez-Rodríguez, Carlos Esparza-Ponce, Miguel Ángel Zatarain-Ontiveros, Juan Carlos Barrera de León
OBJECTIVE: To describe the early complications of esophageal replacement with colon in children. METHODS: Descriptive cross-sectional study from 2005 to 2011 in pediatric patients diagnosed with alkali intake, esophageal atresia or esophageal injury traumatic esophageal replacement handled via retrosternal colon. Descriptive statistical analysis using SPSS 20.0. RESULTS: We included 19 esophageal replacements, age seven (4-15), 13 (68%) male and six (31%) female...
May 2015: Gaceta Médica de México
Mohammad Reza Kalantarhormozi, Majid Assadi, Katayoun Vahdat, Kamyar Asadipooya, Afshin Ostovar, Katayoun Raissi, Hossein Darabi, Shokrollah Farrokhi, Sina Dobaradaran, Maryam Farrokhnia, Iraj Nabipour
The potential link between infection with Chlamydia pneumoniae or Helicobacter pylori and osteoporosis has not been investigated in population-based longitudinal studies. A total of 250 healthy postmenopausal women who participated in a prospective cohort study were evaluated for IgG antibodies directed against C. pneumoniae and H. p ylori, osteoprotegerin (OPG), the receptor activator of nuclear factor kappa B ligand (RANKL), CrossLaps, and osteocalcin. Bone mineral density (BMD) was measured at the femoral neck and lumbar spine at baseline and at follow-up 5...
July 2016: Journal of Bone and Mineral Metabolism
Jesús Membrila-Mondragón, Aidé Tamara Staines-Boone, Luz María Sánchez-Sánchez, María Dolores Ruiz-Pedraza
INTRODUCTION: Primary immunodeficiencies comprise diseases that impair the immune system. Clinical manifestations are characterized by recurrent respiratory infections, which may be complicated by bronchiectasis, peribronchial thickening, abscesses, bullae, and pulmonary fibrosis. The aim of this study was to determine pulmonary complications in pediatric primary immunodeficiency by type. RESULTS. We included 65 patients, 28 patients with humoral immunodeficiency, four with cellular immunodeficiency, 13 with well-defined syndromes, and 20 with phagocytic defects...
March 2015: Gaceta Médica de México
A P Shavrin, Ia B Khovaeva, B V Golovskoĭ, M D Berg
With a purpose of identifying and ranking factors influencing remodeling of vascular wall in 168 practically healthy subjects (71 men, 97 women) aged 30-60 years we conducted a study of risk factors of cardiovascular disease, and infectious, immunological, inflammatory and metabolic parameters. Using artificial neural network we found that process of remodeling of vascular wall was most significantly impacted by: cytomegalovirus and hlamydia neumoniae infections, decreased number of T-lymphocytes, development of latent vascular microinflammation, and diastolic blood pressure above 80 mm Hg...
2014: Kardiologiia
Antoni Torres, José Barberán, Miquel Falguera, Rosario Menéndez, Jesús Molina, Pedro Olaechea, Alejandro Rodríguez
Community-acquired pneumonia (CAP) is an infectious respiratory disease with an incidence that ranges from 3 to 8 cases per 1,000 inhabitants per year. This incidence increases with age and comorbidities. Forty per cent of CAP patients require hospitalization and around 10% of these patients are admitted in an Intensive Care Unit (ICU). Several studies have suggested that the implementation of clinical guidelines has a positive impact in the outcome of patients including mortality and length of stay. The more recent and used guidelines are those from Infectious Diseases Society of America/American Thoracic Society, published in 2007, the 2009 from the British Thoracic Society, and that from the European Respiratory Society/European Society of Clinical Microbiology and Infectious Diseases, published in 2010...
March 2, 2013: Medicina Clínica
María Jesús Pérez-Granda, Patricia Muñoz, Carmen Heras, Guiomar Sánchez, Jordi Rello, Emilio Bouza
OBJECTIVE: User-friendly scores to assess knowledge of guidelines for prevention of ventilator-associated pneumonia (VAP) are scarce and have mainly evaluated nurses, but not students or physicians. Gaps between knowledge and actual clinical practice have not been sufficiently analyzed. We assessed knowledge of and adherence to guidelines for prevention of VAP among physicians, nurses, and students in adult ICUs. METHODS: All adult ICU healthcare workers were invited to complete a 20-point questionnaire...
July 2013: Respiratory Care
M Giannella, B Pinilla, J A Capdevila, J Martínez Alarcón, P Muñoz, J López Álvarez, E Bouza
Patients with pneumonia treated in the internal medicine department (IMD) are often at risk of healthcare-associated pneumonia (HCAP). The importance of HCAP is controversial. We invited physicians from 72 IMDs to report on all patients with pneumonia hospitalized in their department during 2 weeks (one each in January and June 2010) to compare HCAP with community-acquired pneumonia (CAP) and hospital-acquired pneumonia (HAP). We analysed 1002 episodes of pneumonia: 58.9% were CAP, 30.6% were HCAP and 10.4% were HAP...
August 2012: Clinical Microbiology and Infection
Francisco Sanz, Marcos I Restrepo, Estrella Fernández, Eric M Mortensen, María Carmen Aguar, Angela Cervera, Eusebi Chiner, Jose Blanquer
BACKGROUND: Hypoxemia may influence the prognosis of patients with mild pneumonia, regardless of the initial CURB-65 score (confusion, blood urea nitrogen > 20 mg/dL, respiratory rate > 30 breaths/min, blood pressure < 90/60 mm Hg, and age ≥ 65 y). OBJECTIVE: To determine the risk factors associated with hypoxemia and the influence of hypoxemia on clinical outcomes in hospitalized patients with mild pneumonia. METHODS: We performed a multicenter prospective cohort study of 585 consecutive hospitalized patients with mild pneumonia (CURB-65 groups 0 and 1)...
May 2011: Respiratory Care
M Llauradó, S Labeau, D Vandijck, J Rello, A Rosa, A Riera, E Gallart, R Moreno, K Vandewoude, R Piñer, M L Benítez, S Blot
OBJECTIVES: To assess Southern European intensive care unit nurses' knowledge about evidence-based guidelines for the prevention of ventilator-associated pneumonia and to compare these findings with a pan-European perspective. DESIGN: A sub-analysis from an observational study performed using a 9-questions, multiple-choice questionnaire performed during the period October 2006 - March 2007. SETTING: Six Southern European countries, selected from 22 participant European countries...
January 2011: Medicina Intensiva
Noris Moreno-Flagge, Vicente Bayard, Evelia Quirós, Tomás Alonso
The aim is to review the encephalitis in infants and adolescents as well as its etiology, clinical manifestation, epidemiology, physiopathology, diagnostic methods and treatment, and the neuropsyquiatric signs appearing an influenza epidemy. Encephalitis is an inflammation of the central nervous system (CNS) which involves the brain. The clinical manifestations usually are: headache, fever and confusional stage. It could also be manifested as seizures, personality changes, or psiqyiatric symptoms. The clinical manifestations are related to the virus and the cell type affected in the brain...
2009: Medicina
Fiona Walsh
Doripenem is a new parental 1-beta-methyl carbapenem which, unlike imipenem, does not require the addition of cilastatin on administration because of the protection afforded to doripenem by the 1-beta-methyl component. It combines the in vitro activities of imipenem and ertapenem against gram-positive bacteria with the in vitro activity of meropenem against gram-negative bacteria. It has excellent bactericidal activity against Streptococcus neumoniae. Carbapenem resistant mutants were selected with less frequency and lower minimum inhibitory concentrations (MICs) after exposure to doripenem than to imipenem or meropenem...
October 2007: Therapeutics and Clinical Risk Management
B Serra Sanchis, E Martínez Moragón, M Aguar, E Fernández Fabrellas, F Sanz, J Blanquer
OBJECTIVE: Community acquired pneumonia (CAP) of the elderly is an increasingly important growing health problem due to its prevalence and mortality. Among the factors that are usually related with poor evolution are advanced age, poor functional status and coming from a socio-health care institution such as residential homes for the elderly. In this study, we have chosen a population over 70 years of age with limited functional capacity (Barthel Index < 50) in order to know if coming from a residential home for the elderly is an isolated factor that is associated to worse prognosis of CAP...
December 2007: Revista Clínica Española
O N Deĭkina, V Iu Mishin, O V Demikhova
The purpose of this investigation was to enhance the efficiency of differential diagnosis of pneumonia and pulmonary tuberculosis. A hundred and fifty-nine adult patients were examined. These included 78 patients with pulmonary tuberculosis and 81 with community-acquired p neumonia. The clinical features of infiltrative pulmonary tuberculosis (n = 48) and mild community-acquired pneumonia (n = 51) were compared. The course of caseous pneumonia (n = 30) was compared with that of moderate and severe community-acquired pneumonia (n = 30)...
2007: Problemy Tuberkuleza i Bolezneĭ Legkikh
Mateu Cabré, Mateu Serra-Prat, Ignasi Bolíbar, Román Pallarés
BACKGROUND AND OBJECTIVE: To determine whether there are differences between the prognostic factors associated with 30-days mortality in patients 65-84 year-old and patients over 84 years hospitalized for community-acquired pneumonia (CAP). PATIENTS AND METHOD: An observational study with retrospective data collection was carried out in a representative sample of all CAP in-patients of 27 general hospitals. Data regarding comorbidities, signs and symptoms on admission, radiological and laboratory examinations, and complications during hospitalization were recorded...
July 8, 2006: Medicina Clínica
Maria Angeles Marcos, Marta Camps, Tomás Pumarola, José Antonio Martinez, Esteban Martinez, Josep Mensa, Elisa Garcia, Georgina Peñarroja, Póvilas Dambrava, Inmaculada Casas, Maria Teresa Jiménez de Anta, Antoni Torres
BACKGROUND: The role of viruses in community-acquired pneumonia may have been previously underestimated. We aimed to study the incidence and clinical characteristics of community-acquired pneumonia (CAP) due to respiratory viruses in adults adding PCR to routine conventional laboratory tests. METHODS: Consecutive adult patients diagnosed of CAP from January 2003 to March 2004 were included. Conventional tests including cultures of blood, sputum, urine antigen detection of Streptococcus pneumoniae and Legionella pneumophila, and paired serologies were routinely performed...
2006: Antiviral Therapy
C M Luna, P Aruj, M S Niederman, J Garzón, D Violi, A Prignoni, F Ríos, S Baquero, S Gando
Inappropriate therapy (IT) and delayed initiation of appropriate therapy (DIAT) result in inadequate therapy in patients with ventilator-associated pneumonia (VAP). The aim of the current study was to assess the impact of DIAT in VAP. A total of 76 mechanically ventilated patients with bacteriologically confirmed VAP were prospectively evaluated in the intensive care unit of six hospitals in Buenos Aires, Argentina. Appropriate therapy was defined as coverage of all the identified pathogens by the antimicrobial therapy administered at the time of VAP clinical diagnosis...
January 2006: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
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