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https://www.readbyqxmd.com/read/28431952/evaluation-of-patient-preparedness-for-surgery-a-randomized-controlled-trial
#1
Kristie A Greene, Allison M Wyman, Lauren A Scott, Stuart Hart, Lennox Hoyte, Renee Bassaly
BACKGROUND: Patient preparedness for pelvic reconstructive surgery has important implications for patient satisfaction and perception of improvement after surgery. The ideal method in which to optimally prepare patients for surgery has not been determined. OBJECTIVE: To evaluate the impact of a preoperative patient education video on patient preparedness prior to sacrocolpopexy as measured by a preoperative preparedness questionnaire (PPQ). STUDY DESIGN: We performed a single-blind, randomized stratified clinical trial at a single academic center evaluating the use of a preoperative patient education video as an adjunct to preoperative counseling on patient preparedness...
April 18, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28431118/combining-human-epigenetics-and-sleep-studies-in-c-elegans-a-cross-species-approach-for-finding-conserved-genes-regulating-sleep
#2
Huiyan Huang, Yong Zhu, Melissa N Eliot, Valerie S Knopik, John E McGeary, Mary A Carskadon, Anne C Hart
Study Objectives: We aimed to test a combined approach to identify conserved genes regulating sleep and to explore the association between DNA methylation and sleep length. Methods: We identified candidate genes associated with shorter versus longer sleep duration in college students based on DNA methylation using Illumina Infinium HumanMethylation450 BeadChip arrays. Orthologous genes in Caenorhabditiselegans were identified and we examined whether their loss of function affected C...
April 18, 2017: Sleep
https://www.readbyqxmd.com/read/28430501/metric-independence-of-vacuum-and-force-free-electromagnetic-fields
#3
Abraham I Harte
Electromagnetic fields which solve the vacuum Maxwell equations in one spacetime are well known to also be solutions in all spacetimes with conformally related metrics. This provides a sense in which electromagnetism alone cannot be used to measure certain aspects of geometry. We show that there is actually much more which cannot be so measured; relatively little of a spacetime's geometry is in fact imprinted in any particular electromagnetic field. This is demonstrated by finding a much larger class of metric transformations-involving five free functions-which preserve Maxwell solutions both in vacuum, without local currents, and also for the force-free electrodynamics associated with a tenuous plasma...
April 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28429157/scenes-as-micro-cultures-examining-heterogeneity-of-hiv-risk-behavior-among-gay-bisexual-and-other-men-who-have-sex-with-men-in-toronto-canada
#4
Syed W Noor, Barry D Adam, David J Brennan, David A Moskowitz, Sandra Gardner, Trevor A Hart
Using latent class analysis (LCA), we examined patterns of participation in multiple scenes, how sexual risk practices vary by scene, and psychosocial factors associated with these patterns among 470 gay, bisexual, and other men who have sex with men (GBM) recruited from Toronto. We calculated posterior probability of being in a class from participation in nine separate scenes. We used Entropy, the Bayesian information criterion and the Lo-Mendel-Rubin likelihood ratio test to identify the best fit model. Fit indices suggested a four-class solution...
April 20, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/28428630/hinge-deleted-igg4-blocker-therapy-for-acetylcholine-receptor-myasthenia-gravis-in-rhesus-monkeys
#5
Mario Losen, Aran F Labrijn, Vivianne H van Kranen-Mastenbroek, Maarten L Janmaat, Krista G Haanstra, Frank J Beurskens, Tom Vink, Margreet Jonker, Bert A 't Hart, Marina Mané-Damas, Peter C Molenaar, Pilar Martinez-Martinez, Eline van der Esch, Janine Schuurman, Marc H de Baets, Paul W H I Parren
Autoantibodies against ion channels are the cause of numerous neurologic autoimmune disorders. Frequently, such pathogenic autoantibodies have a restricted epitope-specificity. In such cases, competing antibody formats devoid of pathogenic effector functions (blocker antibodies) have the potential to treat disease by displacing autoantibodies from their target. Here, we have used a model of the neuromuscular autoimmune disease myasthenia gravis in rhesus monkeys (Macaca mulatta) to test the therapeutic potential of a new blocker antibody: MG was induced by passive transfer of pathogenic acetylcholine receptor-specific monoclonal antibody IgG1-637...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28428561/a-general-framework-for-predicting-delayed-responses-of-ecological-communities-to-habitat-loss
#6
Youhua Chen, Tsung-Jen Shen
Although biodiversity crisis at different spatial scales has been well recognised, the phenomena of extinction debt and immigration credit at a crossing-scale context are, at best, unclear. Based on two community patterns, regional species abundance distribution (SAD) and spatial abundance distribution (SAAD), Kitzes and Harte (2015) presented a macroecological framework for predicting post-disturbance delayed extinction patterns in the entire ecological community. In this study, we further expand this basic framework to predict diverse time-lagged effects of habitat destruction on local communities...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28424901/driving-with-a-neurodegenerative-disorder-an-overview-of-the-current-literature
#7
REVIEW
Milou Jacobs, Ellen P Hart, Raymund A C Roos
Driving is important for employment, social activities, and for the feeling of independence. The decision to cease driving affects the quality of life and has been associated with reduced mobility, social isolation, and sadness. Patients with neurodegenerative disorders can experience difficulties while driving due to their cognitive, motor, and behavioral impairments. The aim of this review is to summarize the available literature on changes in driving competence and behavior in patients with neurodegenerative disorders, with a particular focus on Huntington's (HD), Parkinson's (PD), and Alzheimer's disease (AD)...
April 19, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28422898/internet-and-social-media-use-after-traumatic-brain-injury-a-traumatic-brain-injury-model-systems-study
#8
Christina Baker-Sparr, Tessa Hart, Thomas Bergquist, Jennifer Bogner, Laura Dreer, Shannon Juengst, David Mellick, Therese M OʼNeil-Pirozzi, Angelle M Sander, Gale G Whiteneck
OBJECTIVES: To characterize Internet and social media use among adults with moderate to severe traumatic brain injury (TBI) and to compare demographic and socioeconomic factors associated with Internet use between those with and without TBI. SETTING: Ten Traumatic Brain Injury Model Systems centers. PARTICIPANTS: Persons with moderate to severe TBI (N = 337) enrolled in the TBI Model Systems National Database and eligible for follow-up from April 1, 2014, to March 31, 2015...
April 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28421178/applying-precision-public-health-to-prevent-preterm-birth
#9
REVIEW
John P Newnham, Matthew W Kemp, Scott W White, Catherine A Arrese, Roger J Hart, Jeffrey A Keelan
Preterm birth (PTB) is one of the major health-care challenges of our time. Being born too early is associated with major risks to the child with potential for serious consequences in terms of life-long disability and health-care costs. Discovering how to prevent PTB needs to be one of our greatest priorities. Recent advances have provided hope that a percentage of cases known to be related to risk factors may be amenable to prevention; but the majority of cases remain of unknown cause, and there is little chance of prevention...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28421005/autoimmune-aspects-of-neurodegenerative-and-psychiatric-diseases-a-template-for-innovative-therapy
#10
REVIEW
Peter de Haan, Hans C Klein, Bert A 't Hart
Neurodegenerative and psychiatric diseases (NPDs) are today's most important group of diseases, surpassing both atherosclerotic cardiovascular disease and cancer in morbidity incidence. Although NPDs have a dramatic impact on our society because of their high incidence, mortality, and severe debilitating character, remarkably few effective interventions have become available. The current treatments, if available, comprise the lifelong intake of general immunosuppressants to delay disease progression or neurotransmitter antagonists/agonists to dampen undesired behaviors...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28419817/objectively-measured-physical-activity-in-patients-after-anterior-cruciate-ligament-reconstruction
#11
David R Bell, Karin A Pfeiffer, Lisa A Cadmus-Bertram, Stephanie M Trigsted, Adam Kelly, Eric G Post, Joseph M Hart, Dane B Cook, Warren R Dunn, Christopher Kuenze
BACKGROUND: Returning to a healthy level of physical activity is among the most commonly discussed clinical goals for patients recovering from anterior cruciate ligament reconstruction (ACLR). However, physical activity has not been objectively measured in this population. PURPOSE: To investigate differences in the mean time (min/d) spent in moderate-to-vigorous physical activity (MVPA) as well as the daily step count (steps/d) between patients who underwent ACLR and matched controls...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28418487/notice-of-retraction-and-replacement-oostdijk-et-al-effects-of-decontamination-of-the-oropharynx-and-intestinal-tract-on-antibiotic-resistance-in-icus-a-randomized-clinical-trial-jama-2014-312-14-1429-1437
#12
Evelien A N Oostdijk, Jozef Kesecioglu, Marcus J Schultz, Caroline E Visser, Evert de Jonge, Einar H R van Essen, Alexandra T Bernards, Ilse Purmer, Roland Brimicombe, Dennis Bergmans, Frank van Tiel, Frank H Bosch, Ellen Mascini, Arjanne van Griethuysen, Alexander Bindels, Arjan Jansz, Fred A L van Steveninck, Wil C van der Zwet, Jan Willem Fijen, Steven Thijsen, Remko de Jong, Joke Oudbier, Adrienne Raben, Eric van der Vorm, Mirelle Koeman, Philip Rothbarth, Annemieke Rijkeboer, Paul Gruteke, Helga Hart, Paul Peerbooms, Lex J Winsser, Anne-Marie W van Elsacker-Niele, Kees Demmendaal, Afke Brandenburg, Anne Marie G A de Smet, Marc J M Bonten
No abstract text is available yet for this article.
April 18, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28418444/associations-between-cancer-predisposition-testing-panel-genes-and-breast-cancer
#13
Fergus J Couch, Hermela Shimelis, Chunling Hu, Steven N Hart, Eric C Polley, Jie Na, Emily Hallberg, Raymond Moore, Abigail Thomas, Jenna Lilyquist, Bingjian Feng, Rachel McFarland, Tina Pesaran, Robert Huether, Holly LaDuca, Elizabeth C Chao, David E Goldgar, Jill S Dolinsky
Importance: Germline pathogenic variants in BRCA1 and BRCA2 predispose to an increased lifetime risk of breast cancer. However, the relevance of germline variants in other genes from multigene hereditary cancer testing panels is not well defined. Objective: To determine the risks of breast cancer associated with germline variants in cancer predisposition genes. Design, Setting, and Participants: A study population of 65 057 patients with breast cancer receiving germline genetic testing of cancer predisposition genes with hereditary cancer multigene panels...
April 13, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28416020/patient-and-family-centered-performance-measures-focused-on-actionable-processes-of-care-for-persistent-and-chronic-critical-illness-protocol-for-a-systematic-review
#14
Louise Rose, Laura Istanboulian, Laura Allum, Lisa Burry, Craig Dale, Nicholas Hart, Claire Kydonaki, Pam Ramsay, Natalie Pattison, Bronwen Connolly
BACKGROUND: Approximately 5 to 10% of critically ill patients transition from acute critical illness to a state of persistent and in some cases chronic critical illness. These patients have unique and complex needs that require a change in the clinical management plan and overall goals of care to a focus on rehabilitation, symptom relief, discharge planning, and in some cases, end-of-life care. However, existing indicators and measures of care quality, and tools such as checklists, that foster implementation of best practices, may not be sufficiently inclusive in terms of actionable processes of care relevant to these patients...
April 17, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28415728/lipid-degradation-promotes-prostate-cancer-cell-survival
#15
Harri M Itkonen, Michael Brown, Alfonso Urbanucci, Gregory Tredwell, Chung Ho Lau, Stefan Barfeld, Claire Hart, Ingrid J Guldvik, Mandeep Takhar, Hannelore V Heemers, Nicholas Erho, Katarzyna Bloch, Elai Davicioni, Rita Derua, Etienne Waelkens, James L Mohler, Noel Clarke, Johan V Swinnen, Hector C Keun, Ole P Rekvig, Ian G Mills
Prostate cancer is the most common male cancer and androgen receptor (AR) is the major driver of the disease. Here we show that Enoyl-CoA delta isomerase 2 (ECI2) is a novel AR-target that promotes prostate cancer cell survival. Increased ECI2 expression predicts mortality in prostate cancer patients (p = 0.0086). ECI2 encodes for an enzyme involved in lipid metabolism, and we use multiple metabolite profiling platforms and RNA-seq to show that inhibition of ECI2 expression leads to decreased glucose utilization, accumulation of fatty acids and down-regulation of cell cycle related genes...
March 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415097/p544the-importance-of-contractile-reserve-when-assessing-asymptomatic-patients-with-aortic-stenosis
#16
J J Van Zalen, S Badiani, L Hart, A Marshall, N Patel, G Lloyd
Asymptomatic patients may exhibit symptoms during objective exercise testing, but whether symptoms are due to the obstructively of the valve (typified by the mean gradient) or underlying ventricular function remains unknown. While the mean gradient is an easy parameter to measure no consensus about the measurement of contractile reserve exists. Longitudinal abnormalities may occur in the presence of a normal ejection fraction and the augmentation of these parameters is poorly described. To obtain an objective regarding patients exercise ability is best determined using cardiopulmonary exercise testing...
December 1, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28414170/importance-of-patient-reported-individualized-goals-when-assessing-outcomes-for-adult-spinal-deformity-asd-initial-experience-with-a-patient-generated-index-pgi
#17
Justin K Scheer, Malla Keefe, Virginie Lafage, Michael P Kelly, Shay Bess, Douglas C Burton, Robert A Hart, Amit Jain, Baron S Lonner, Themistocles S Protopsaltis, Richard Hostin, Christopher I Shaffrey, Justin S Smith, Frank Schwab, Christopher P Ames
BACKGROUND CONTEXT: Current metrics to assess a patient's health-related quality-of-life (HRQOL) may not reflect a true change in a patient's specific perception of what is most important to them. PURPOSE: To describe the initial experience of a Patient Generated Index (PGI) in which patients create their own outcome domains. STUDY DESIGN: Single center prospective study PATIENT SAMPLE: Adult spinal deformity (ASD) patients OUTCOME MEASURES: Oswestry Disability Index (ODI), Short-Form 36 (SF36:PCS/MCS), Scoliosis research society 22r (SRS22r), and PGI METHODS: ODI, SF36, SRS22r, and PGI were administered preoperatively and postoperatively at 6wks, 3mo, 6mo, and 1 and 2yrs...
April 13, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28411863/is-pelvic-sentinel-node-biopsy-necessary-for-lower-extremity-and-trunk-melanomas
#18
Darryl Schuitevoerder, Stanley P L Leong, Jonathan S Zager, Richard L White, Eli Avisar, Heidi Kosiorek, Amylou Dueck, Jeanine Fortino, Mohammed Kashani-Sabet, Kyle Hart, John T Vetto
OBJECTIVE: There is currently no consensus regarding how to address pelvic sentinel lymph nodes (PSLNs) in melanoma. Thus, our objectives were to identify the incidence and clinical impact of PSLNs. METHODS: Retrospective review of a prospectively collected multi-institutional melanoma database. RESULTS: Of 2476 cases of lower extremity and trunk melanomas, 227 (9%) drained to PSLNs (181 to both PSLNs and superficial (inguinal or femoral) sentinel lymph nodes (SSLN) and 46 to PSLNs alone)...
March 27, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28408859/measurement-of-the-formula-see-text-production-cross-section-using-events-in-the-formula-see-text-final-state-in-pp-collisions-at-formula-see-text
#19
V Khachatryan, A M Sirunyan, A Tumasyan, W Adam, E Asilar, T Bergauer, J Brandstetter, E Brondolin, M Dragicevic, J Erö, M Flechl, M Friedl, R Frühwirth, V M Ghete, C Hartl, N Hörmann, J Hrubec, M Jeitler, A König, I Krätschmer, D Liko, T Matsushita, I Mikulec, D Rabady, N Rad, B Rahbaran, H Rohringer, J Schieck, J Strauss, W Waltenberger, C-E Wulz, O Dvornikov, V Makarenko, V Zykunov, V Mossolov, N Shumeiko, J Suarez Gonzalez, S Alderweireldt, E A De Wolf, X Janssen, J Lauwers, M Van De Klundert, H Van Haevermaet, P Van Mechelen, N Van Remortel, A Van Spilbeeck, S Abu Zeid, F Blekman, J D'Hondt, N Daci, I De Bruyn, K Deroover, S Lowette, S Moortgat, L Moreels, A Olbrechts, Q Python, S Tavernier, W Van Doninck, P Van Mulders, I Van Parijs, H Brun, B Clerbaux, G De Lentdecker, H Delannoy, G Fasanella, L Favart, R Goldouzian, A Grebenyuk, G Karapostoli, T Lenzi, A Léonard, J Luetic, T Maerschalk, A Marinov, A Randle-Conde, T Seva, C Vander Velde, P Vanlaer, R Yonamine, F Zenoni, F Zhang, A Cimmino, T Cornelis, D Dobur, A Fagot, G Garcia, M Gul, I Khvastunov, D Poyraz, S Salva, R Schöfbeck, A Sharma, M Tytgat, W Van Driessche, E Yazgan, N Zaganidis, H Bakhshiansohi, C Beluffi, O Bondu, S Brochet, G Bruno, A Caudron, S De Visscher, C Delaere, M Delcourt, B Francois, A Giammanco, A Jafari, P Jez, M Komm, V Lemaitre, A Magitteri, A Mertens, M Musich, C Nuttens, K Piotrzkowski, L Quertenmont, M Selvaggi, M Vidal Marono, S Wertz, N Beliy, W L Aldá Júnior, F L Alves, G A Alves, L Brito, C Hensel, A Moraes, M E Pol, P Rebello Teles, E Belchior Batista Das Chagas, W Carvalho, J Chinellato, A Custódio, E M Da Costa, G G Da Silveira, D De Jesus Damiao, C De Oliveira Martins, S Fonseca De Souza, L M Huertas Guativa, H Malbouisson, D Matos Figueiredo, C Mora Herrera, L Mundim, H Nogima, W L Prado Da Silva, A Santoro, A Sznajder, E J Tonelli Manganote, A Vilela Pereira, S Ahuja, C A Bernardes, S Dogra, T R Fernandez Perez Tomei, E M Gregores, P G Mercadante, C S Moon, S F Novaes, Sandra S Padula, D Romero Abad, J C Ruiz Vargas, A Aleksandrov, R Hadjiiska, P Iaydjiev, M Rodozov, S Stoykova, G Sultanov, M Vutova, A Dimitrov, I Glushkov, L Litov, B Pavlov, P Petkov, W Fang, M Ahmad, J G Bian, G M Chen, H S Chen, M Chen, Y Chen, T Cheng, C H Jiang, D Leggat, Z Liu, F Romeo, S M Shaheen, A Spiezia, J Tao, C Wang, Z Wang, H Zhang, J Zhao, Y Ban, G Chen, Q Li, S Liu, Y Mao, S J Qian, D Wang, Z Xu, C Avila, A Cabrera, L F Chaparro Sierra, C Florez, J P Gomez, C F González Hernández, J D Ruiz Alvarez, J C Sanabria, N Godinovic, D Lelas, I Puljak, P M Ribeiro Cipriano, T Sculac, Z Antunovic, M Kovac, V Brigljevic, D Ferencek, K Kadija, S Micanovic, L Sudic, T Susa, A Attikis, G Mavromanolakis, J Mousa, C Nicolaou, F Ptochos, P A Razis, H Rykaczewski, D Tsiakkouri, M Finger, M Finger, E Carrera Jarrin, Y Assran, T Elkafrawy, A Mahrous, B Calpas, M Kadastik, M Murumaa, L Perrini, M Raidal, A Tiko, C Veelken, P Eerola, J Pekkanen, M Voutilainen, J Härkönen, T Järvinen, V Karimäki, R Kinnunen, T Lampén, K Lassila-Perini, S Lehti, T Lindén, P Luukka, J Tuominiemi, E Tuovinen, L Wendland, J Talvitie, T Tuuva, M Besancon, F Couderc, M Dejardin, D Denegri, B Fabbro, J L Faure, C Favaro, F Ferri, S Ganjour, S Ghosh, A Givernaud, P Gras, G Hamel de Monchenault, P Jarry, I Kucher, E Locci, M Machet, J Malcles, J Rander, A Rosowsky, M Titov, A Zghiche, A Abdulsalam, I Antropov, S Baffioni, F Beaudette, P Busson, L Cadamuro, E Chapon, C Charlot, O Davignon, R Granier de Cassagnac, M Jo, S Lisniak, P Miné, M Nguyen, C Ochando, G Ortona, P Paganini, P Pigard, S Regnard, R Salerno, Y Sirois, T Strebler, Y Yilmaz, A Zabi, J-L Agram, J Andrea, A Aubin, D Bloch, J-M Brom, M Buttignol, E C Chabert, N Chanon, C Collard, E Conte, X Coubez, J-C Fontaine, D Gelé, U Goerlach, A-C Le Bihan, K Skovpen, P Van Hove, S Gadrat, S Beauceron, C Bernet, G Boudoul, E Bouvier, C A Carrillo Montoya, R Chierici, D Contardo, B Courbon, P Depasse, H El Mamouni, J Fan, J Fay, S Gascon, M Gouzevitch, G Grenier, B Ille, F Lagarde, I B Laktineh, M Lethuillier, L Mirabito, A L Pequegnot, S Perries, A Popov, D Sabes, V Sordini, M Vander Donckt, P Verdier, S Viret, T Toriashvili, Z Tsamalaidze, C Autermann, S Beranek, L Feld, A Heister, M K Kiesel, K Klein, M Lipinski, A Ostapchuk, M Preuten, F Raupach, S Schael, C Schomakers, J Schulz, T Verlage, H Weber, V Zhukov, A Albert, M Brodski, E Dietz-Laursonn, D Duchardt, M Endres, M Erdmann, S Erdweg, T Esch, R Fischer, A Güth, M Hamer, T Hebbeker, C Heidemann, K Hoepfner, S Knutzen, M Merschmeyer, A Meyer, P Millet, S Mukherjee, M Olschewski, K Padeken, T Pook, M Radziej, H Reithler, M Rieger, F Scheuch, L Sonnenschein, D Teyssier, S Thüer, V Cherepanov, G Flügge, F Hoehle, B Kargoll, T Kress, A Künsken, J Lingemann, T Müller, A Nehrkorn, A Nowack, I M Nugent, C Pistone, O Pooth, A Stahl, M Aldaya Martin, T Arndt, C Asawatangtrakuldee, K Beernaert, O Behnke, U Behrens, A A Bin Anuar, K Borras, A Campbell, P Connor, C Contreras-Campana, F Costanza, C Diez Pardos, G Dolinska, G Eckerlin, D Eckstein, T Eichhorn, E Eren, E Gallo, J Garay Garcia, A Geiser, A Gizhko, J M Grados Luyando, P Gunnellini, A Harb, J Hauk, M Hempel, H Jung, A Kalogeropoulos, O Karacheban, M Kasemann, J Keaveney, C Kleinwort, I Korol, D Krücker, W Lange, A Lelek, J Leonard, K Lipka, A Lobanov, W Lohmann, R Mankel, I-A Melzer-Pellmann, A B Meyer, G Mittag, J Mnich, A Mussgiller, E Ntomari, D Pitzl, R Placakyte, A Raspereza, B Roland, M Ö Sahin, P Saxena, T Schoerner-Sadenius, C Seitz, S Spannagel, N Stefaniuk, G P Van Onsem, R Walsh, C Wissing, V Blobel, M Centis Vignali, A R Draeger, T Dreyer, E Garutti, D Gonzalez, J Haller, M Hoffmann, A Junkes, R Klanner, R Kogler, N Kovalchuk, T Lapsien, T Lenz, I Marchesini, D Marconi, M Meyer, M Niedziela, D Nowatschin, F Pantaleo, T Peiffer, A Perieanu, J Poehlsen, C Sander, C Scharf, P Schleper, A Schmidt, S Schumann, J Schwandt, H Stadie, G Steinbrück, F M Stober, M Stöver, H Tholen, D Troendle, E Usai, L Vanelderen, A Vanhoefer, B Vormwald, M Akbiyik, C Barth, S Baur, C Baus, J Berger, E Butz, R Caspart, T Chwalek, F Colombo, W De Boer, A Dierlamm, S Fink, B Freund, R Friese, M Giffels, A Gilbert, P Goldenzweig, D Haitz, F Hartmann, S M Heindl, U Husemann, I Katkov, S Kudella, P Lobelle Pardo, H Mildner, M U Mozer, Th Müller, M Plagge, G Quast, K Rabbertz, S Röcker, F Roscher, M Schröder, I Shvetsov, G Sieber, H J Simonis, R Ulrich, J Wagner-Kuhr, S Wayand, M Weber, T Weiler, S Williamson, C Wöhrmann, R Wolf, G Anagnostou, G Daskalakis, T Geralis, V A Giakoumopoulou, A Kyriakis, D Loukas, I Topsis-Giotis, S Kesisoglou, A Panagiotou, N Saoulidou, E Tziaferi, I Evangelou, G Flouris, C Foudas, P Kokkas, N Loukas, N Manthos, I Papadopoulos, E Paradas, N Filipovic, G Bencze, C Hajdu, P Hidas, D Horvath, F Sikler, V Veszpremi, G Vesztergombi, A J Zsigmond, N Beni, S Czellar, J Karancsi, A Makovec, J Molnar, Z Szillasi, M Bartók, P Raics, Z L Trocsanyi, B Ujvari, S Bahinipati, S Choudhury, P Mal, K Mandal, A Nayak, D K Sahoo, N Sahoo, S K Swain, S Bansal, S B Beri, V Bhatnagar, R Chawla, U Bhawandeep, A K Kalsi, A Kaur, M Kaur, R Kumar, P Kumari, A Mehta, M Mittal, J B Singh, G Walia, Ashok Kumar, A Bhardwaj, B C Choudhary, R B Garg, S Keshri, S Malhotra, M Naimuddin, N Nishu, K Ranjan, R Sharma, V Sharma, R Bhattacharya, S Bhattacharya, K Chatterjee, S Dey, S Dutt, S Dutta, S Ghosh, N Majumdar, A Modak, K Mondal, S Mukhopadhyay, S Nandan, A Purohit, A Roy, D Roy, S Roy Chowdhury, S Sarkar, M Sharan, S Thakur, P K Behera, R Chudasama, D Dutta, V Jha, V Kumar, A K Mohanty, P K Netrakanti, L M Pant, P Shukla, A Topkar, T Aziz, S Dugad, G Kole, B Mahakud, S Mitra, G B Mohanty, B Parida, N Sur, B Sutar, S Banerjee, S Bhowmik, R K Dewanjee, S Ganguly, M Guchait, Sa Jain, S Kumar, M Maity, G Majumder, K Mazumdar, T Sarkar, N Wickramage, S Chauhan, S Dube, V Hegde, A Kapoor, K Kothekar, A Rane, S Sharma, H Behnamian, S Chenarani, E Eskandari Tadavani, S 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Kunnawalkam Elayavalli, S Kyriacou, A Lath, K Nash, H Saka, S Salur, S Schnetzer, D Sheffield, S Somalwar, R Stone, S Thomas, P Thomassen, M Walker, A G Delannoy, M Foerster, J Heideman, G Riley, K Rose, S Spanier, K Thapa, O Bouhali, A Celik, M Dalchenko, M De Mattia, A Delgado, S Dildick, R Eusebi, J Gilmore, T Huang, E Juska, T Kamon, R Mueller, Y Pakhotin, R Patel, A Perloff, L Perniè, D Rathjens, A Rose, A Safonov, A Tatarinov, K A Ulmer, N Akchurin, C Cowden, J Damgov, F De Guio, C Dragoiu, P R Dudero, J Faulkner, E Gurpinar, S Kunori, K Lamichhane, S W Lee, T Libeiro, T Peltola, S Undleeb, I Volobouev, Z Wang, S Greene, A Gurrola, R Janjam, W Johns, C Maguire, A Melo, H Ni, P Sheldon, S Tuo, J Velkovska, Q Xu, M W Arenton, P Barria, B Cox, J Goodell, R Hirosky, A Ledovskoy, H Li, C Neu, T Sinthuprasith, X Sun, Y Wang, E Wolfe, F Xia, C Clarke, R Harr, P E Karchin, J Sturdy, D A Belknap, C Caillol, S Dasu, L Dodd, S Duric, B Gomber, M Grothe, M Herndon, A Hervé, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, I Ojalvo, T Perry, G A Pierro, G Polese, T Ruggles, A Savin, N Smith, W H Smith, D Taylor, N Woods
The cross section of top quark-antiquark pair production in proton-proton collisions at [Formula: see text] is measured by the CMS experiment at the LHC, using data corresponding to an integrated luminosity of 2.2[Formula: see text]. The measurement is performed by analyzing events in which the final state includes one electron, one muon, and two or more jets, at least one of which is identified as originating from hadronization of a b quark. The measured cross section is [Formula: see text], in agreement with the expectation from the standard model...
2017: European Physical Journal. C, Particles and Fields
https://www.readbyqxmd.com/read/28406494/laser-capture-microdissection-of-pancreatic-acinar-cells-to-identify-proteomic-alterations-in-a-murine-model-of-caerulein-induced-pancreatitis
#20
John P Shapiro, Hannah M Komar, Baris Hancioglu, Lianbo Yu, Ming Jin, Yuko Ogata, Phil A Hart, Zobeida Cruz-Monserrate, Gregory B Lesinski, Darwin L Conwell
OBJECTIVES: Chronic pancreatitis (CP) is characterized by inflammation and fibrosis of the pancreas, leading to pain, parenchymal damage, and loss of exocrine and endocrine function. There are currently no curative therapies; diagnosis remains difficult and aspects of pathogenesis remain unclear. Thus, there is a need to identify novel biomarkers to improve diagnosis and understand pathophysiology. We hypothesize that pancreatic acinar regions contain proteomic signatures relevant to disease processes, including secreted proteins that could be detected in biofluids...
April 13, 2017: Clinical and Translational Gastroenterology
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