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https://www.readbyqxmd.com/read/28381202/tranexamic-acid-for-acute-intracerebral-hemorrhage-growth-predicted-by-spot-sign-trial-rationale-and-design
#1
Liping Liu, Yilong Wang, Xia Meng, Na Li, Ying Tan, Ximing Nie, Dacheng Liu, Xingquan Zhao
Rationale Acute intracerebral hemorrhage inflicts a high-economic and -health burden. Computed tomography angiography spot sign is a predictor of hematoma expansion, is associated with poor clinical outcome and is an important stratifying variable for patients treated with haemostatic therapy. Aims We aim to compare the effect of treatment with tranexamic acid to placebo for the prevention of hemorrhage growth in patients with high-risk acute intracerebral hemorrhage with a positive spot sign. Design The tranexamic acid for acute intracerebral hemorrhage growth predicted by spot sign (TRAIGE) is a prospective, multicenter, placebo-controlled, double-blind, investigator-led, randomized clinical trial that will include an estimated 240 participants...
April 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/12824968/a-randomized-trial-on-the-management-of-low-grade-squamous-intraepithelial-lesion-cytology-interpretations
#2
RANDOMIZED CONTROLLED TRIAL
(no author information available yet)
OBJECTIVE: This study was undertaken to compare alternative strategies for the initial management of low-grade squamous intraepithelial lesion (LSIL) cytology. STUDY DESIGN: A total of 1572 women with a community-based LSIL interpretation were randomly assigned to immediate colposcopy, triage based on enrollment HPV DNA testing and liquid-based cytology at a colposcopy referral threshold of high-grade squamous intraepithelial lesion (HSIL), or conservative management based on repeat cytology at a referral threshold of HSIL...
June 2003: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/12824967/results-of-a-randomized-trial-on-the-management-of-cytology-interpretations-of-atypical-squamous-cells-of-undetermined-significance
#3
RANDOMIZED CONTROLLED TRIAL
(no author information available yet)
OBJECTIVE: This study was undertaken to compare alternative strategies for the initial management of a cytologic diagnosis of atypical squamous cells of undetermined significance (ASCUS). STUDY DESIGN: A total of 3488 women with a community-based ASCUS interpretation were randomly assigned to immediate colposcopy, triage that was based on enrollment HPV DNA testing and liquid-based cytology at a colposcopy referral threshold of high-grade squamous intraepithelial lesion (HSIL), or conservative management based on repeat cytology at a referral threshold of HSIL...
June 2003: American Journal of Obstetrics and Gynecology
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