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https://www.readbyqxmd.com/read/29241264/-smoke-free-psychiatry-in-germany-a-closer-look
#1
Andrea Linhardt, Raphael Haider, Verena Rampeltshammer, Christoph Kröger, Tobias Rüther
Objective In order to protect non-smokers, the federal states of Germany have adopted a law that provides for extensive smoking bans. In many of these federal laws, acute psychiatric facilities are treated as an exception. Therefore, it is often up to the institutions themselves to develop and enforce regulations. The aim of this study was to evaluate the situation in acute psychiatric facilities. Methods The survey was created on the basis of previously evaluated questionnaires and consisted of 53 questions...
December 14, 2017: Fortschritte der Neurologie-Psychiatrie
https://www.readbyqxmd.com/read/29241142/unmet-needs-burden-of-treatment-and-patient-engagement-in-multiple-sclerosis-a-combined-perspective-from-the-ms-in-the-21st-century-steering-group
#2
Peter Rieckmann, Diego Centonze, Irina Elovaara, Gavin Giovannoni, Eva Havrdová, Jurg Kesselring, Gisela Kobelt, Dawn Langdon, Sarah A Morrow, Celia Oreja-Guevara, Sven Schippling, Christoph Thalheim, Heidi Thompson, Patrick Vermersch, Karen Aston, Birgit Bauer, Christy Demory, Maria Paz Giambastiani, Jana Hlavacova, Jocelyne Nouvet-Gire, George Pepper, Maija Pontaga, Emma Rogan, Chrystal Rogalski, Pieter van Galen, Ali-Frédéric Ben-Amor
BACKGROUND: Patient engagement is vital in multiple sclerosis (MS) in order to optimise outcomes for patients, society and healthcare systems. It is essential to involve all stakeholders in potential solutions, working in a multidisciplinary way to ensure that people with MS (PwMS) are included in shared decision-making and disease management. To start this process, a collaborative, open environment between PwMS and healthcare professionals (HCPs) is required so that similarities and disparities in the perception of key areas in patient care and unmet needs can be identified...
November 21, 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29241013/libreta-computerized-optimization-and-code-synthesis-for-electron-repulsion-integral-evaluation
#3
Jun Zhang
A new library called LIBRETA for the evaluation of electron repulsion integrals (ERIs) and their first and second derivatives over segmented and contracted Gaussian functions is developed. Our LIBRETA is optimized from three aspects: (1) The Obara-Saika, Dupuis-Rys-King, and McMurchie-Davidson method are all employed. The recurrence relations involved are optimized by tree-search for each combination of angular momenta, and in the best case, 50% of the intermediates can be eliminated to reduce the computational cost...
December 14, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/29240887/associations-between-unemployment-and-heavy-episodic-drinking-from-adolescence-to-midlife-in-sweden-and-finland
#4
Noora Berg, Olli Kiviruusu, Taina Huurre, Tomi Lintonen, Pekka Virtanen, Anne Hammarström
Background: Unemployment and alcohol use have often been found to correlate and to act as risk factors for each other. However, only few studies have examined these associations at longitudinal settings extending over several life phases. Moreover, previous studies have mostly used total consumption or medical diagnoses as the indicator, whereas subclinical measures of harmful alcohol use, such as heavy episodic drinking (HED), have been used rarely. The aim of this study was to examine the associations between HED and unemployment from adolescence to midlife in two Nordic countries...
December 12, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29240853/the-evaluation-of-medical-inpatients-who-are-admitted-on-long-term-opioid-therapy-for-chronic-pain
#5
Hilary Mosher, Shoshana J Herzig, Itai Danovitch, Christina Boutsicaris, Sameer Hassamal, Karl Wittnebel, Azadeh Dashti, Teryl Nuckols
Individuals who are on long-term opioid therapy (LTOT) for chronic noncancer pain are frequently admitted to the hospital with acute pain, exacerbations of chronic pain, or comorbidities. Consequently, hospitalists find themselves faced with complex treatment decisions in the context of uncertainty about the effectiveness of LTOT as well as concerns about risks of overdose, opioid use disorders, and adverse events. Our multidisciplinary team sought to synthesize guideline recommendations and primary literature relevant to assessing medical inpatients on LTOT, with the objective of assisting practitioners in balancing effective pain treatment and opioid risk reduction...
December 6, 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29240345/applications-of-genomic-medicine-in-the-treatment-of-diseases
#6
Kimmo Porkka, Mikko Niemi, Elli Leppä, Imre Västrik, Jukka Partanen, Jarkko Ihalainen, Sakari Jokiranta, Pasi Pöllänen
Individualized medicine, based on a detailed mapping of the patient's disease mechanisms, is becoming an essential part of treatment for an increasing number of diseases. In the past few years, the possibility to determine the abnormal genome and transcriptome of diseased cells at a reasonable cost has been the major advance. The vast amount of data accumulated from one patient will set requirements for data extraction tools, in order to have the essential information affecting the treatment of the patient information quickly and reliably at the disposal of attending physicians...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29240088/contrast-enhanced-quarter-talbot-images
#7
Saifollah Rasouli, Davud Hebri
In this paper a rigorous mathematical approach to the near-field diffraction of 1D periodic structures at quarter-Talbot distances is presented. At the beginning of the paper, we present a mathematical investigation on the behavior of periodic functions under squaring by the aid of Fourier analysis. We determine sufficient conditions for a periodic function in which its fundamental period is halved by squaring. We show that if Fourier expansion of a given periodic function includes only coefficients with odd indexes, and minimum difference of the indexes is 2, then its fundamental period halves by squaring...
December 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29239858/prediction-of-breast-cancer-risk-using-a-machine-learning-approach-embedded-with-a-locality-preserving-projection-algorithm
#8
Morteza Heidari, Abolfazl Zargari Khuzani, Alan B Hollingsworth, Gopichandh Danala, Seyedehnafiseh Mirniaharikandehei, Yuchen Qiu, Hong Liu, Bin Zheng
In order to automatically identify a set of effective mammographic image features and build an optimal breast cancer risk stratification model, this study aims to investigate advantages of applying a machine learning approach embedded with a locally preserving projection (LPP) based feature combination and regeneration algorithm to predict short-term breast cancer risk. A dataset involving negative mammograms acquired from 500 women was assembled. This dataset was divided into two age-matched classes of 250 high risk cases in which cancer was detected in the next subsequent mammography screening and 250 low risk cases, which remained negative...
December 14, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29239779/gender-differences-in-residual-effect-of-prior-drop-jumps-on-oxygen-uptake-during-heavy-cycling-exercise
#9
Neringa Baranauskienė, Sandra Kilikevičienė, Loreta Stasiulė, Genuvaitė Civinskienė, Arvydas Stasiulis
BACKGROUND AND OBJECTIVE: Unaccustomed eccentric or eccentric-concentric exercise leaves us stiff and sore the next day and can cause muscle damage. The data about the residual effect of prior eccentric-concentric exercises on oxygen uptake (VO2) during constant cycling exercise in women or the data about differences of such effect between genders are scarce. Therefore, the aim of this study was to assess differences of the residual effect of PDJ on VO2 during HCE and indirect muscle damage parameters between women and men...
November 1, 2017: Medicina
https://www.readbyqxmd.com/read/29239459/ischemic-left-ventricle-systolic-dysfunction-an-evidence-based-approach-in-diagnostic-tools-and-therapeutics
#10
Eduardo Gomes Lima, Felipe Pereira Câmara de Carvalho, Jaime Paula Pessoa Linhares Filho, Fabio Grunspun Pitta, Carlos Vicente Serrano
Coronary artery disease (CAD) associated with left ventricular systolic dysfunction is a condition related to poor prognosis. There is a lack of robust evidence in many aspects related to this condition, from definition to treatment. Ischemic cardiomyopathy is a spectrum ranging from stunned myocardium associated with myocardial fibrosis to hibernating myocardium and repetitive episodes of ischemia. In clinical practice, relevance lies in identifying the myocardium that has the ability to recover its contractile reserve after revascularization...
September 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/29239305/a-mean-field-approach-to-kondo-attractive-hubbard-model
#11
Natanael de Carvalho Costa, José Pimentel de Lima, Thereza Paiva, M ElMassalami, R Dos Santos
With the purpose of investigating coexistence between magnetic order and superconductivity, we consider a model in which conduction electrons interact with each other, via an attractive Hubbard on-site coupling $U$, and with local moments on every site, via a Kondo-like coupling, $J$. The model is solved on a simple cubic lattice through a Hartree-Fock approximation, within a `semi-classical' framework which allows spiral magnetic modes to be stabilized. For a fixed electronic density, $n_c$, the small $J$ region of the ground state ($T=0$) phase diagram displays spiral antiferromagnetic (SAFM) states for small $U$...
December 14, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29239248/use-of-and-microbial-resistance-to-antibiotics-in-china-a-path-to-reducing-antimicrobial-resistance
#12
Dan Cui, Xinliang Liu, Peter Hawkey, Hao Li, Quan Wang, Zongfu Mao, Jing Sun
We analyzed China's current use of and microbial resistance to antibiotics, and possible means of reducing antimicrobial resistance. Interventions like executive orders within clinical settings and educational approach with vertical approaches rather than an integrated strategy to curb the use of antimicrobials remain limited. An underlying problem is the system of incentives that has resulted in the intensification of inappropriate use by health professionals and patients. There is an urgent need to explore the relationship between financial and non-financial incentives for providers and patients, to eliminate inappropriate incentives...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/29238607/protocol-for-a-feasibility-randomised-controlled-trial-of-the-use-of-physical-activity-monitors-in-an-exercise-referral-setting-the-pacers-study
#13
Jemma Hawkins, Michelle Edwards, Joanna Charles, Russell Jago, Mark Kelson, Kelly Morgan, Simon Murphy, Emily Oliver, Sharon Simpson, Rhiannon Tudor Edwards, Graham Moore
Background: Exercise referral schemes are recommended by the National Institute for Clinical Excellence (NICE) for physical activity promotion among inactive patients with health conditions or risk factors. Whilst there is evidence for the initial effectiveness and cost-effectiveness of such schemes for increasing physical activity, evidence of long-term effects is limited. Techniques such as goal setting, self-monitoring and personalised feedback may support motivation for physical activity...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29238427/hiv-associated-nephropathy-in-africa-pathology-clinical-presentation-and-strategy-for-prevention
#14
REVIEW
Nazik Elmalaika Husain, Mohamed H Ahmed, Ahmed O Almobarak, Sufian K Noor, Wadie M Elmadhoun, Heitham Awadalla, Clare L Woodward, Dushyant Mital
The human immunodeficiency virus (HIV) infection can lead to progressive decline in renal function known as HIV-associated nephropathy (HIVAN). Importantly, individuals of African ancestry are more at risk of developing HIVAN than their European descent counterparts. An in-depth search on Google Scholar, Medline and PubMed was conducted using the terms "HIVAN" and "pathology and clinical presentation", in addition to "prevalence and risk factors for HIVAN", with special emphasis on African countries for any articles published between 1990 and 2017...
January 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29238402/expressing-accessory-proteins-in-cellulolytic-yarrowia-lipolytica-to-improve-the-conversion-yield-of-recalcitrant-cellulose
#15
Zhong-Peng Guo, Sophie Duquesne, Sophie Bozonnet, Jean-Marc Nicaud, Alain Marty, Michael Joseph O'Donohue
Background: A recently constructed cellulolytic Yarrowia lipolytica is able to grow efficiently on an industrial organosolv cellulose pulp, but shows limited ability to degrade crystalline cellulose. In this work, we have further engineered this strain, adding accessory proteins xylanase II (XYNII), lytic polysaccharide monooxygenase (LPMO), and swollenin (SWO) from Trichoderma reesei in order to enhance the degradation of recalcitrant substrate. Results: The production of EG I was enhanced using a promoter engineering strategy...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/29238395/cognitive-dysfunction-in-asian-patients-with-depression-cogdad-a-cross-sectional-study
#16
Srisurapanont Manit, Mok Yee Ming, Yang Yen Kuang, Chan Herng-Nieng, Della Constantine D, Zainal Nor Zuraida, Jambunathan Stephen, Amir Nurmiati, Kalita Pranabi
Background: Cognitive dysfunction is a predominant symptom of Major Depressive Disorder (MDD), contributing to functional impairment. Objective: The primary objective of this study was to assess and describe perceived cognitive dysfunction amongst Asian patients diagnosed with MDD. The secondary objective was to explore the associations between depression severity, perceived cognitive dysfunction and functional disability. Methods: This was a multi-country, multi-centre, cross-sectional study...
2017: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/29238299/the-htm-spatial-pooler-a-neocortical-algorithm-for-online-sparse-distributed-coding
#17
Yuwei Cui, Subutai Ahmad, Jeff Hawkins
Hierarchical temporal memory (HTM) provides a theoretical framework that models several key computational principles of the neocortex. In this paper, we analyze an important component of HTM, the HTM spatial pooler (SP). The SP models how neurons learn feedforward connections and form efficient representations of the input. It converts arbitrary binary input patterns into sparse distributed representations (SDRs) using a combination of competitive Hebbian learning rules and homeostatic excitability control...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/29238169/bioequivalence-study-of-two-formulations-of-flupirtine-maleate-capsules-in-healthy-male-chinese-volunteers-under-fasting-and-fed-conditions
#18
Yanfang Liu, Hua Huo, Zhibo Zhao, Wenli Hu, Yujia Sun, Yunbiao Tang
Aim: This study developed a high-performance liquid chromatography-tandem mass spectrometry method to simultaneously determine the concentrations of flupirtine and its major active metabolite D-13223 in human plasma in order to assess the bioequivalence (BE) of two flupirtine maleate capsules among healthy male Chinese volunteers under fasting and fed conditions. Materials and methods: There were two single-center, randomized, single-dose, open-label, laboratory-blinded, two-period, cross-over studies which included 24 healthy male Chinese volunteers under fasting and fed conditions, respectively...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29238116/a-schutzian-analysis-of-prayer-with-perspectives-from-linguistic-philosophy
#19
K Hoshikawa, M Staudigl
In this paper, we propose to analyze the phenomenon of Christian prayer by way of combining two different analytical frameworks. We start by applying Schutz's theories of "intersubjectivity," "inner time," "politheticality," and "multiple realities," and then proceed by drawing on the ideas and insights of linguistic philosophers, notably, Wittgenstein's "language-game," Austin's "speech act," and Evans's "logic of self-involvement". In conjoining these accounts, we wish to demonstrate how their combination sheds new light on understanding the phenomenon of prayer...
2017: Human Studies
https://www.readbyqxmd.com/read/29237183/-volunteers-in-refugee-help-is-health-promotion-by-public-health-services-necessary
#20
Valerie Andrees, Beke Freyer, Ingrid Borgmeier, Hans-Jürgen Galle, Joachim Westenhöfer
Objectives To investigate health-related strains and resources of volunteers in refugee help. Methods Qualitative interviews with 10 volunteers in refugee help as well as 11 interviews with experts involved in coordinative tasks were conducted, transcribed and analysed using qualitative content analysis. Results Volunteers' work in refugee help is experienced as a strong resource. Volunteers receive a lot of thankfulness and appreciation and experience their work as enriching and enhancing self-worth. On the other hand, they also experience several stresses and problems...
December 13, 2017: Das Gesundheitswesen
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