keyword
https://read.qxmd.com/read/38663871/spherical-nucleic-acid-mediated-spatial-matching-guided-nonenzymatic-dna-circuits-for-the-prediction-and-prevention-of-malignant-tumor-invasion
#21
JOURNAL ARTICLE
Weijun Wang, Congcong Li, Shasha Luo, Zai-Sheng Wu
Detection of intracellular miRNAs, especially sensitive imaging of in vivo miRNAs, is vital to the precise prediction and timely prevention of tumorgenesis but remains a technical challenge in terms of nuclease resistance and signal amplification. Here, we demonstrate a gold nanoparticle-based spherical nucleic acid-mediated spatial matching-guided nonenzymatic DNA circuit (SSDC) for efficient screening of intracellular miRNAs and, in turn, finding cancerous tissues in living organisms before the appearance of clinical symptoms...
April 25, 2024: Analytical Chemistry
https://read.qxmd.com/read/38662429/assessing-electronic-health-literacy-in-individuals-with-the-post-covid-19-condition-using-the-german-revised-ehealth-literacy-scale-validation-study
#22
JOURNAL ARTICLE
Matthias Marsall, Hannah Dinse, Julia Schröder, Eva-Maria Skoda, Martin Teufel, Alexander Bäuerle
BACKGROUND: The eHealth Literacy Scale (eHEALS) is a widely used instrument for measuring eHealth literacy (eHL). However, little is known so far about whether the instrument is valid for the assessment of eHL in persons who are affected by the post-COVID-19 condition. This is particularly important as people with the post-COVID-19 condition are frequently affected by false information from the internet. OBJECTIVE: The objective of our study was to evaluate the validity and reliability of the German Revised eHealth Literacy Scale (GR-eHEALS) in individuals with the post-COVID-19 condition...
April 25, 2024: JMIR Formative Research
https://read.qxmd.com/read/38661636/the-time-course-of-encoding-specific-and-gist-episodic-memory-representations-among-young-and-older-adults
#23
JOURNAL ARTICLE
Nathaniel R Greene, Moshe Naveh-Benjamin
How rapidly can we encode the specifics versus the gist of episodic memories? Competing theories have opposing answers, but empirical tests are based primarily on tasks of item memory. Few studies have addressed this question with tasks measuring the binding of event components (e.g., a person and a location), which forms the core of episodic memory. None of these prior studies included older adults, whose episodic memories are less specific in nature. We addressed this critical gap by presenting face-scene pairs (e...
April 25, 2024: Journal of Experimental Psychology. General
https://read.qxmd.com/read/38660058/coaching-adaptive-skill-and-expertise-in-premier-league-football-academies-paving-a-way-forward-for-research-and-practice
#24
JOURNAL ARTICLE
Michael Ashford, Jamie Taylor, Danny Newcombe, Áine MacNamara, Stephen Behan, Simon Phelan, Scott McNeill
Within the domain of coach education researchers have long called for a paradigm shift, whereby the quality of coaching practice is no longer measured against a checklist of prescribed competencies. This desire to evolve coach education and development, has been aligned to the need to better identify, understand and utilise what adaptive skill and expertise looks, sounds and feels like across specific sport coaching contexts. This paper outlines a broader research plan for the Premier League to drive the progress of research informed practice, in turn shaping a coach development agenda focused on developing adaptive and skilful coaches within Academies...
2024: Frontiers in sports and active living
https://read.qxmd.com/read/38659598/adolescent-suicide-risk-factors-and-the-integration-of-social-emotional-skills-in-school-based-prevention-programs
#25
REVIEW
Xin-Qiao Liu, Xin Wang
Adolescents are considered one of the most vulnerable groups affected by suicide. Rapid changes in adolescents' physical and mental states, as well as in their lives, significantly and undeniably increase the risk of suicide. Psychological, social, family, individual, and environmental factors are important risk factors for suicidal behavior among teenagers and may contribute to suicide risk through various direct, indirect, or combined pathways. Social-emotional learning is considered a powerful intervention measure for addressing the crisis of adolescent suicide...
April 19, 2024: World Journal of Psychiatry
https://read.qxmd.com/read/38656952/chatgpt-literate-or-intelligent-about-un-sustainable-development-goals
#26
JOURNAL ARTICLE
Raghu Raman, Hiran H Lathabai, Santanu Mandal, Payel Das, Tavleen Kaur, Prema Nedungadi
Generative AI tools, such as ChatGPT, are progressively transforming numerous sectors, demonstrating a capacity to impact human life dramatically. This research seeks to evaluate the UN Sustainable Development Goals (SDGs) literacy of ChatGPT, which is crucial for diverse stakeholders involved in SDG-related policies. Experimental outcomes from two widely used Sustainability Assessment tests-the UN SDG Fitness Test and Sustainability Literacy Test (SULITEST) - suggest that ChatGPT exhibits high SDG literacy, yet its comprehensive SDG intelligence needs further exploration...
2024: PloS One
https://read.qxmd.com/read/38654288/attitudes-toward-communication-skills-with-learner-needs-assessment-within-radiology-residency-programs-in-china-a-cross-sectional-survey
#27
JOURNAL ARTICLE
GengPeng Lian, Yubin Xiao, Yingling Huang, Huanpeng Wang, Lipeng Huang, Hongwu Yang, Chunmin Zhu, Wei Mei, Ruibin Huang
BACKGROUND: Communication skills (CS) represent a core competency in radiology residency training. However, no structured curriculum exists to train radiology residents in CS in China. The aim of this study was to evaluate the status and prevalence of doctor-patient communication training among radiology residents in nine Chinese accredited radiology residency training programs and to determine whether there is a perceived need for a formalized curriculum in this field. METHODS: We administered a cross-sectional online survey to radiology residents involved in CS training at nine standard residency training programs in China...
April 23, 2024: BMC Research Notes
https://read.qxmd.com/read/38653728/-jordanian-nurses-perceptions-of-disaster-preparedness-and-core-competencies
#28
JOURNAL ARTICLE
Alia N Alfouqaha, Mohammad R Al Osta, Anas H Khalifeh, Islam Ali Oweidat
OBJECTIVE: This study aims to identify the Jordanian nurses' perception of their disaster preparedness and core competencies. METHODS: A descriptive, cross-sectional research design was used. The data was collected via an online self-reported questionnaire using the disaster preparedness evaluation tool and the core disaster competencies tool. RESULTS: A total of 126 nurses participated in the study. Jordanian nurses had moderate to high levels of core disaster competencies and moderate levels of disaster preparedness...
April 24, 2024: Disaster Medicine and Public Health Preparedness
https://read.qxmd.com/read/38652193/professionalization-of-clinical-ethics-consultants-a-need-for-liability-protection
#29
JOURNAL ARTICLE
Claudia R Sotomayor, Christopher Spevak, Edward R Grant
Clinical Ethics Consultation (CEC) has grown significantly in the last decade, and efforts are being made to professionalize the practice. The American Society for Bioethics and Humanities (ASBH) has been instrumental in this process, having published the Code of Ethics and Professional Responsibilities for Healthcare Ethics Consultants and founded and endorsed the creation of the Healthcare Ethics Consultant Certified (HCEC) Certification Commission. The ASBH also published "core competencies" for healthcare ethics consultants and has delineated a clear identity and role of such consultants distinct from that other healthcare professionals...
April 23, 2024: HEC Forum
https://read.qxmd.com/read/38649984/training-the-next-generation-of-community-engaged-physicians-a-mixed-methods-evaluation-of-a-novel-course-for-medical-service-learning-in-the-covid-19-era
#30
JOURNAL ARTICLE
Jack J Scala, Hannah Cha, Kiarash Shamardani, Emma R Rashes, Lehi Acosta-Alvarez, Rishi P Mediratta
BACKGROUND: Medical school curricula strive to train community-engaged and culturally competent physicians, and many use service learning to instill these values in students. The current standards for medical service learning frameworks have opportunities for improvement, such as encouraging students to have more sustainable and reciprocal impact and to ingrain service learning as a value to carry throughout their careers rather than a one-time experience. PEDS 220: A COVID-19 Elective is a Stanford University course on the frontlines of this shift; it provides timely education on the COVID-19 pandemic, integrating community-oriented public health work to help mitigate its impact...
April 22, 2024: BMC Medical Education
https://read.qxmd.com/read/38649901/impact-of-a-coaching-program-on-resident-perceptions-of-communication-confidence-and-feedback-quality
#31
JOURNAL ARTICLE
Carl A Gold, Rachel Jensen, Marzena Sasnal, Heather S Day, Rebecca K Miller-Kuhlmann, Rebecca L Blankenburg, Caroline E Rassbach, Arden M Morris, James R Korndorffer, Aussama K Nassar
BACKGROUND: While communication is an essential skill for providing effective medical care, it is infrequently taught or directly assessed, limiting targeted feedback and behavior change. We sought to evaluate the impact of a multi-departmental longitudinal residency communication coaching program. We hypothesized that program implementation would result in improved confidence in residents' communication skills and higher-quality faculty feedback. METHODS: The program was implemented over a 3-year period (2019-2022) for surgery and neurology residents at a single institution...
April 22, 2024: BMC Medical Education
https://read.qxmd.com/read/38649874/15-year-survivorship-of-a-unique-dual-modular-femoral-stem-in-primary-hip-arthroplasty
#32
JOURNAL ARTICLE
David F Scott, Kade Eppich, Edin Mehić, Celeste Gray, Crystal Lederhos Smith, Michael Johnston
BACKGROUND: Hip offset, version, and length are interdependent femoral variables which determine stability and leg length. Balancing these competing variables remains a core challenge in hip arthroplasty. The potential benefits of modular femoral stems have been overshadowed by higher rates of failure. The objective of this study was to assess the survivorship of a unique dual-modular femoral stem at an average 15-year follow-up period. METHODS: The records of all patients with osteoarthritis who underwent primary total hip arthroplasty with this device between 2004-2009 were reviewed...
April 22, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38644965/sterically-selective-3-3-cycloaromatization-in-the-on-surface-synthesis-of-nanographenes
#33
JOURNAL ARTICLE
Amogh Kinikar, Xiao-Ye Wang, Marco Di Giovannantonio, José I Urgel, Pengcai Liu, Kristjan Eimre, Carlo A Pignedoli, Samuel Stolz, Max Bommert, Shantanu Mishra, Qiang Sun, Roland Widmer, Zijie Qiu, Akimitsu Narita, Klaus Müllen, Pascal Ruffieux, Roman Fasel
Surface-catalyzed reactions have been used to synthesize carbon nanomaterials with atomically predefined structures. The recent discovery of a gold surface-catalyzed [3 + 3] cycloaromatization of isopropyl substituted arenes has enabled the on-surface synthesis of arylene-phenylene copolymers, where the surface activates the isopropyl substituents to form phenylene rings by intermolecular coupling. However, the resulting polymers suffered from undesired cross-linking when more than two molecules reacted at a single site...
April 17, 2024: ACS Nanosci Au
https://read.qxmd.com/read/38644476/exploring-variations-in-ipc-competencies-a-cross-sectional-study-among-healthcare-professionals-in-northwest-china
#34
JOURNAL ARTICLE
Qinglan Zhao, Xiaoqing Cui, Ting Liu, Hanxue Li, Miaoyue Shi, Li Wang
BACKGROUND: This cross-sectional study investigates infection prevention and control (IPC) competencies among healthcare professionals in northwest China, examining the influence of demographic factors, job titles, education, work experience, and hospital levels. METHODS: Data from 874 respondents across 47 hospitals were collected through surveys assessing 16 major IPC domains. Statistical analyses, including Mann-Whitney tests, were employed to compare competencies across variables...
April 22, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38643700/discovering-the-importance-of-health-informatics-education-competencies-in-healthcare-practice-a-focus-group-interview
#35
JOURNAL ARTICLE
Pauleen Mannevaara, Ulla-Mari Kinnunen, Nicole Egbert, Ursula Hübner, Pedro Vieira-Marques, Paulino Sousa, Kaija Saranto
BACKGROUND: As healthcare and especially health technology evolve rapidly, new challenges require healthcare professionals to take on new roles. Consequently, the demand for health informatics competencies is increasing, and achieving these competencies using frameworks, such as Technology Informatics Guiding Reform (TIGER), is crucial for future healthcare. AIM: The study examines essential health informatics and educational competencies and health informatics challenges based on TIGER Core Competency Areas...
April 18, 2024: International Journal of Medical Informatics
https://read.qxmd.com/read/38643057/-human-resources-in-the-national-health-system-medical-education-sespas-report-2024
#36
REVIEW
Felipe Rodríguez de Castro, Teresa Carrillo Díaz, Arcadi Gual I Sala, Jordi Palés Argullós
The problems posed by medical education in Spain are diverse. This paper analyzes the system currently used to select candidates who will be admitted to a public faculty of medicine in Spain and some issues arising from the unprecedented increase in both public and private medical schools in our country. The importance of generic competencies in today's medicine and the need to return to a core design in specialist training are other aspects that are discussed. The degree of development of advanced accreditation diplomas and areas of specific competence is also subject to analysis...
March 19, 2024: Gaceta Sanitaria
https://read.qxmd.com/read/38640556/effects-of-game-based-learning-integrated-with-the-self-regulated-learning-strategy-on-nursing-students-entrustable-professional-activities-a-quasi-experimental-study
#37
JOURNAL ARTICLE
Ching-Yi Chang, Intan Setiani, Darmawansah Darmawansah, Jie Chi Yang
BACKGROUND: In the field of nursing education, the expertise and knowledge required to perform Leopold's Maneuvers are critical, forming an integral part of Entrustable Professional Activities for nursing students. As a result, mastering Leopold's Maneuvers has become a core component of nursing education. Despite this, the prevailing didactic methods in many nursing courses tend to limit interactive and contextual learning experiences, which can hinder students' ability to engage deeply with the subject matter...
April 10, 2024: Nurse Education Today
https://read.qxmd.com/read/38640229/gpr1-and-cmklr1-control-lipid-metabolism-to-support-development-of-clear-cell-renal-cell-carcinoma
#38
JOURNAL ARTICLE
Dazhi Wang, Iqbal Mahmud, Vijay S Thakur, Sze Kiat Tan, Daniel G Isom, David B Lombard, Mark L Gonzalgo, Oleksandr N Kryvenko, Philip L Lorenzi, Vanina T Tcheuyap, James Brugarolas, Scott M Welford
Clear cell renal cell carcinoma (ccRCC), the most common type of kidney cancer, is largely incurable in the metastatic setting. ccRCC is characterized by excessive lipid accumulation that protects cells from stress and promotes tumor growth, suggesting that the underlying regulators of lipid storage could represent potential therapeutic targets. Here, we evaluated the regulatory roles of GPR1 and CMKLR1, two G-protein coupled receptors of the pro-tumorigenic adipokine chemerin that is involved in ccRCC lipid metabolism...
April 19, 2024: Cancer Research
https://read.qxmd.com/read/38639519/workload-reduction-through-automated-documentation-in-intensive-and-intermediate-care-a-monocentric-observational-study
#39
JOURNAL ARTICLE
A N Flinspach, J M Leimgruber, V Neef, K Zacharowski, F J Raimann
OBJECTIVE: The global coronavirus pandemic has placed an unprecedented and enormous burden on health systems worldwide. In addition to a shortage of resources, nurses were also confronted with high levels of sick leave and an increasing exodus from the profession. Automating documentation obligations is an effective way of reducing the burden on the workplace. PATIENTS AND METHODS: The study was conducted at a tertiary university hospital. The time required for the manual documentation of administered medication and dose changes of syringe and infusion pumps was recorded using the patient data management system (PDMS) representing all intensive and intermediate care wards (n = 6)...
April 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38633024/enrichment-of-core-competencies-to-maximize-health-system-impact-an-analysis-of-an-embedded-research-training-program
#40
JOURNAL ARTICLE
Bahar Kasaai, Erin Thompson, Richard H Glazier, Meghan McMahon
INTRODUCTION: The Health System Impact (HSI) Fellowship is an embedded research training program that aims to prepare doctoral trainees and postdoctoral fellows for stronger career readiness and greater impact as emerging leaders within and beyond the academy, including in learning health systems (LHS). The program supports fellows to develop 10 leadership and research competencies that comprise the Enriched Core Competency Framework in Health Services and Policy Research through a combination of experiential learning, mentorship, and professional development training...
April 2024: Learning Health Systems
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