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Core competencies

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https://www.readbyqxmd.com/read/28329653/introducing-public-health-themes-in-clinical-dermatology
#1
Scott A Norton
The ACGME's Core Competencies comprise six domains, which in turn contain dozens of often overlapping milestones. Several competencies explicitly invoke public health topics - but if one wears the right set of lenses, nearly every milestone, nearly every aspect of health and medicine, can be viewed from a public health perspective. Why then is Dermatology generally taught - and practiced - in an Intensive Care manner, where seemingly unlimited diagnostic & therapeutic efforts focus on single individuals, not the community?In this presentation, I argue that topics of public health concern should not be relegated to the minor leagues of GME...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28327253/the-wolf-will-live-with-the-lamb
#2
Richard Ronay, Joshua M Tybur
Maestripieri et al. pit evolutionary psychology against social psychological and economic perspectives in a winner-take-all empirical battle. In doing so, they risk positioning evolutionary psychology as an antagonistic subdisciplinary enterprise. We worry that such a framing may exacerbate tensions between "competing" scientific perspectives and limit evolutionary psychology's potential to serve as a unifying core theory.
January 2017: Behavioral and Brain Sciences
https://www.readbyqxmd.com/read/28318079/design-and-synthesis-of-galactosylated-bifurcated-ligands-with-nanomolar-affinity-for-lectin-leca-from-pseudomonas-aeruginosa
#3
Anthony Angeli, Muchen Li, Lucie Dupin, Gerard Vergoten, Mathieu Noel, Mimouna Madaoui, Shuai Wang, Albert Meyer, Thomas Gehin, Sebastien Vidal, Jean-Jacques Vasseur, Yann Chevolot, Francois Morvan
Lectin LecA of Pseudomonas aeruginosa is established as a virulent factor. Glycoclusters targeting LecA able to compete with human glycoconjugates present on epithelial cells are promising candidates to treat P. aeruginosa infection. A family of 32 glycodendrimers of generation 0 and 1 displaying bifurcated bis-galactosides has been designed to interact with LecA. The influence of both the central multivalent core and the aglycon of these glycodendrimers on their affinity toward LecA has been evaluated using a microarray technology both qualitatively for a rapid screening of the binding properties but also quantitatively (Kd) leading to high affinity LecA ligands with Kd values in the low nanomolar range (Kd = 22 nM for the best one)...
March 20, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28306323/a-feasibility-assessment-of-behavioral-based-interviewing-to-improve-candidate-selection-for-a-pulmonary-and-critical-care-medicine-fellowship-program
#4
Geneva Tatem, Maria Kokas, Cathy L Smith, Bruno DiGiovine
Traditional interviews for residency and fellowship training programs are an important component in the selection process, but can be of variable value due to a non-standardized approach. We redesigned the candidate interview process for our large pulmonary and critical care medicine fellowship program in the United States using a behavioral-based interview structure. The primary goal of this approach was to standardize the assessment of candidates within non-cognitive domains with the goal of selecting those with the best fit for our institution's fellowship program...
March 17, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28302329/the-high-performing-radiology-residency-a-case-study
#5
Lu Anne V Dinglasan, Mary H Scanlon
The primary goal of any radiology residency program is to train clinically competent radiologists. However, some radiology programs go above and beyond basic ACGME requirements and produce highly productive radiologists who contribute to the field in research, education and technology. At the core of such residencies are the people who comprise it, including self-motivated, personable residents and faculty who can facilitate excellence from their trainees. Indeed, radiology residencies which create unique programs in response to evolving resident interests can help foster resident-driven research, advocacy, technological innovation and early leadership...
January 14, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28294439/coordination-of-tetravalent-actinides-an-th-iv-u-iv-np-iv-pu-iv-with-dota-from-dimers-to-hexamers
#6
Christelle Tamain, Thomas Dumas, Christoph Hennig, Philippe Guilbaud
Three tetravalent actinide (An(IV)) hexanuclear clusters with the octahedral core [An6(OH)4O4]12+ (An(IV) = U(IV), Np(IV), Pu(IV)) were structurally characterized in solid state and in aqueous solution using single crystal X-ray diffraction, X-ray absorption, IR, Raman and UV-Visible spectroscopy. The observed structure, [An6(OH)4O4(H2O)8(HDOTA)4].HCl/HNO3.nH2O (An = U (I), Np (II), Pu (III)), consists of a An(IV) hexanuclear pseudo-octahedral cluster stabilized by DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) ligands...
March 10, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28291556/teaching-communication-skills-to-radiology-residents
#7
Jason N Itri, Sammy Yacob, Ayman Mithqal
The transition of health care in the United States from volume to value requires a systems-based approach aligning clinical services across the continuum of care. The ability to communicate effectively and resolve conflict is a critical skill within the systems-based model. Recognizing the essential role of communication in medicine, the Accreditation Council of Graduate Medical Education has designated interpersonal and communication skills a core competency for all residents regardless of specialty. Yet, communication skills are often developed through on-the-job training or not at all...
January 17, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28291450/establishing-a-joint-theater-trauma-system-during-phase-zero-operations
#8
Jennifer J Walker, Zsolt T Stockinger, Colin G Chinn
OBJECTIVES: Military personnel risk injury due to accidents, disasters, and military threats during Phase Zero "shaping" operations. Medical facilities must be poised to respond. METHODS: The U.S. Pacific Command (PACOM) Area of Responsibility (AOR) covers more than 50% of the earth's surface; relevant Clinical Practice Guidelines must include the maritime setting and extended evacuation periods. Military hospitals in the region are not connected by a defined Trauma System...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28287538/measurement-of-in-vitro-integration-activity-of-hiv-1-preintegration-complexes
#9
Muthukumar Balasubramaniam, Benem Davids, Amma B Addai, Jui Pandhare, Chandravanu Dash
HIV-1 envelope proteins engage cognate receptors on the target cell surface, which leads to viral-cell membrane fusion followed by the release of the viral capsid (CA) core into the cytoplasm. Subsequently, the viral Reverse Transcriptase (RT), as part of a namesake nucleoprotein complex termed the Reverse Transcription Complex (RTC), converts the viral single-stranded RNA genome into a double-stranded DNA copy (vDNA). This leads to the biogenesis of another nucleoprotein complex, termed the pre-integration complex (PIC), composed of the vDNA and associated virus proteins and host factors...
February 22, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28287025/assessing-interprofessional-education-in-a-student-faculty-collaborative-practice-network
#10
Grace J Young, Marya J Cohen, Bonnie B Blanchfield, Meissa M Jones, Patricia A Reidy, Amy R Weinstein
Although interprofessional relationships are ubiquitous in clinical practice, undergraduate medical students have limited opportunities to develop these relationships in the clinical setting. A few student-faculty collaborative practice networks (SFCPNs) have been working to address this issue, but limited data exist examining the nature and extent of these practices. A systematic survey at a Harvard-affiliated SFCPN is utilised to evaluate the quantity and quality of interprofessional interactions, isolate improvements, and identify challenges in undergraduate interprofessional education (IPE)...
March 12, 2017: Education for Primary Care
https://www.readbyqxmd.com/read/28282142/interplay-between-conformational-heterogeneity-and-hydration-in-the-folding-landscape-of-a-designed-3-helix-bundle
#11
Gregory S Custer, Payel Das, Silvina Matysiak
Water is known to play a critical role in protein folding and stability. Here we develop and employ a coarse-grained (CG) model to directly explore the role of water in shaping the conformational landscape explored during protein folding. For this purpose, we simulate a designed sequence with binary patterning of neutral and hydrophobic residues, which is capable of folding to a three helix bundle in explicit water. We find two folded states of this sequence, with rotation of the helices occurring to trade between hydrophobic packing and water expulsion from the core...
March 10, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28279297/the-academic-medical-system-reinvention-to-survive-the-revolution-in-health-care
#12
REVIEW
Marvin A Konstam, Joseph A Hill, Richard J Kovacs, Robert A Harrington, James A Arrighi, Amit Khera
Academic medical centers (AMCs) are presently facing enormous challenges arising from a prospective decline in government funding for research and education, shifting payment models emphasizing efficiency and value, and increasing competition. Left unabated, these challenges will drive many AMCs to de-emphasize or forsake their core missions in an effort to survive. Stemming from a symposium held at the 2015 Scientific Sessions of the American College of Cardiology titled, "The Academic Medical Center of the Future," we propose a series of changes, including internal restructuring, system-wide partnership, and novel approaches to support research and education, that are designed to better position AMCs to compete and face their growing challenges in a manner that preserves their essential missions...
March 14, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28278456/boosted-random-ferns-for-object-detection
#13
Michael Villamizar, Juan Andrade-Cetto, Alberto Sanfeliu, Francesc Moreno-Noguer
In this paper we introduce the Boosted Random Ferns (BRFs) to rapidly build discriminative classifiers for learning and detecting object categories. At the core of our approach we use standard random ferns, but we introduce four main innovations that let us bring ferns from an instance to a category level, and still retain efficiency. First, we define binary features on the histogram of oriented gradients-domain (as opposed to intensity-), allowing for a better representation of intra-class variability. Second, both the positions where ferns are evaluated within the sliding window, and the location of the binary features for each fern are not chosen completely at random, but instead we use a boosting strategy to pick the most discriminative combination of them...
March 1, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28274231/developing-a-measure-of-mental-health-service-satisfaction-for-use-in-low-income-countries-a-mixed-methods-study
#14
Rosie Mayston, Kassahun Habtamu, Girmay Medhin, Atalay Alem, Abebaw Fekadu, Alehegn Habtamu, Martin Prince, Charlotte Hanlon
BACKGROUND: Service satisfaction is integral to quality of care and measures are therefore considered important indicators of quality. Patient's responses to their experiences of using services are under-researched in the context of mental healthcare in low income countries. Our aim was to use mixed methods to develop a new measure of satisfaction for use among consumers of the new models of mental healthcare which are currently being scaled-up. METHODS: We used qualitative methods to explore the concept of service satisfaction...
March 9, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28273126/struggling-toward-reward-recent-experience-of-anhedonia-interacts-with-motivation-to-predict-reward-pursuit-in-the-face-of-a-stressful-manipulation
#15
Jessica Bryant, E Samuel Winer, Taban Salem, Michael R Nadorff
Anhedonia, or the loss of interest and/or pleasure, is a core symptom of depression. Individuals experiencing anhedonia have difficulty motivating themselves to pursue rewarding stimuli, which can result in dysfunction. Action orientation is a motivational factor that might interact with anhedonia to potentially buffer against this dysfunction, as action-oriented individuals upregulate positive affect to quickly motivate themselves to complete goals in the face of stress. The Effort-Expenditure for Rewards Task (EEfRT) is a promising new method for examining differences in motivation in individuals experiencing anhedonia...
2017: PloS One
https://www.readbyqxmd.com/read/28273108/structure-based-mutational-analysis-of-icat-residues-mediating-negative-regulation-of-%C3%AE-catenin-co-transcriptional-activity
#16
Mélanie J Domingues, Juan Martinez-Sanz, Laura Papon, Lionel Larue, Liliane Mouawad, Jacky Bonaventure
ICAT (Inhibitor of β-CAtenin and TCF) is a small acidic protein that negatively regulates β-catenin co-transcriptional activity by competing with TCF/LEF factors in their binding to β-catenin superhelical core. In melanoma cells, ICAT competes with LEF1 to negatively regulate the M-MITF and NEDD9 target genes. The structure of ICAT consists of two domains: the 3-helix bundle N-terminal domain binds to β-catenin Armadillo (Arm) repeats 10-12 and the C-terminal tail binds to Arm repeats 5-9. To elucidate the structural mechanisms governing ICAT/β-catenin interactions in melanoma cells, three ICAT residues Y15, K19 and V22 in the N-terminal domain, contacting hydrophobic β-catenin residue F660, were mutated and interaction was assessed by immunoprecipitation...
2017: PloS One
https://www.readbyqxmd.com/read/28272909/identifying-common-values-among-seven-health-professions-an-interprofessional-analysis
#17
Sandra Grace, Ev Innes, Beverly Joffe, Leah East, Rosanne Coutts, Susan Nancarrow
This article reviews the competency frameworks of seven Australian health professions to explore relationships among health professions of similar status as reflected in their competency frameworks and to identify common themes and values across the professions. Frameworks were compared using a constructivist grounded theory approach to identify key themes, against which individual competencies for each profession were mapped and compared. The themes were examined for underlying values and a higher order theoretical framework was developed...
March 8, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/28272902/aligning-interprofessional-education-collaborative-sub-competencies-to-a-progression-of-learning
#18
Tina Patel Gunaldo, Kari Fitzmorris Brisolara, Alison H Davis, Robert Moore
In the United States, the Interprofessional Education Collaborative (IPEC) developed four core competencies for interprofessional collaborative practice. Even though the IPEC competencies and respective sub-competencies were not created in a hierarchal manner, one might reflect upon a logical progression of learning as well as learners accruing skills allowing them to master one level of learning and building on the aggregate of skills before advancing to the next level. The Louisiana State University Health-New Orleans Center for Interprofessional Education and Collaborative Practice (CIPECP) determined the need to align the sub-competencies with the level of behavioural expectations in order to simplify the process of developing an interprofessional education experience targeted to specific learning levels...
March 8, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/28272535/european-registration-process-for-clinical-laboratory-geneticists-in-genetic-healthcare
#19
Thomas Liehr, Isabel M Carreira, Dilek Aktas, Egbert Bakker, Marta Rodríguez de Alba, Domenico A Coviello, Lina Florentin, Hans Scheffer, Martina Rincic
Tremendous progress in genetics and genomics led to a wide range of healthcare providers, genetic tests, and more patients who can benefit from these developments. To guarantee and improve the quality of genetic testing, a unified European-based registration for individuals qualified in biomedicine was realized. Therefore a Europe-wide recognition of the profession 'European registered Clinical Laboratory Geneticist (ErCLG)' based on a syllabus of core competences was established which allows for harmonization in professional education...
March 8, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28265321/prepuce-health-and-childhood-circumcision-choices-in-canada
#20
REVIEW
Emmanuel O Abara
INTRODUCTION: Worldwide, almost 100% of boys are born with penises with a "hood" called prepuce or foreskin. In the course of the boy's life, the prepuce can be circumcised, can become affected by diseased (e.g., phimosis), or a can become infected and hurt the neonate (and his sexual partner) in adulthood. The objectives of this report are to: 1) review the state, function, fate, and care of the prepuce in childhood, with focus on the neonate, in Canada; 2) understand the current practice of childhood male circumcision in terms of age, indications, performers, techniques, outcomes, and education; and 3) consider ways to sustain a good healthcare professional-parental dialogue for safe practices that are accessible, acceptable, and culturally sensitive in the care of the prepuce...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
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