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JOURNAL ARTICLE
Sajedeh Seyed-Alipour, Javad Alaghband-Rad, Saba Faraji, Zahra Hooshyari, Mehdi Tehranidoost, Mahtab Motamed
INTRODUCTION: Neuropsychological deficits in areas of Executive Functioning (EF), theory of mind, and central coherence have been well-documented among children and adolescents with autism spectrum disorder (ASD); however, there remains a significant gap in knowledge with regards to neuropsychological profile in adults with ASD. This study aims to investigate the intellectual functioning and neuropsychological profiles of a clinical population of adults with ASD. METHODS: This cross-sectional study included 40 available autistic individuals referred to an adult developmental disorders clinic at a hospital between 2021 and 2022...
April 18, 2024: Applied Neuropsychology. Adult
#2
REVIEW
Camilla Gesi, Luca Giacovelli, Yacob Levin Reibman, Bernardo Dell'Osso
In the last decades, growing caseness for Autism Spectrum Disorder (ASD) has been observed, owing to the diagnostic accretion of low-impairment forms, over and above other possible causes. Unrecognized ASD is likely to be mislabeled as a psychotic disorder (PD), as people in the spectrum may show 'pseudopsychotic' symptoms, resembling both negative and positive symptoms. On the other hand, PDs are likely to be overlooked when they arise in people with ASD, due to the 'diagnostic overshadowing' of new-onset conditions by lifelong core autistic symptoms...
March 26, 2024: Journal of Psychiatric Research
#3
Maciej Dul, Krzysztof Walczewski
In this article, we present the case of an adult patient, whose main problem is episodes of fantasizing and rocking lasting up to 12 hours a day and completely preventing school development. The nature of the disorder in the patient is related to the sinking into fantasies, and not typical obsessions as in OCD. The patient was previously treated with drugs from the SSRI group, neuroleptics (without aripiprazole) and methylphenidate. Only methylphenidate showed some improvement; however, it made the patient feel ‟stiff in thinking"...
December 31, 2023: Psychiatria Polska
#4
JOURNAL ARTICLE
Raymond F Palmer, David Kattari, Rodolfo Rincon, Claudia S Miller
BACKGROUND: We sought to replicate our 2015 findings linking chemical intolerance in parents with the risk of their children developing autism and/or ADHD. Drawing upon our 2021 discovery of a strong association between chemical intolerance and mast cells, we propose an explanation for this link. METHODS: In a population-based survey of U.S. adults, we used the internationally validated Quick Environmental Exposure and Sensitivity Inventory (QEESI) to assess symptom severity and chemical intolerance...
March 5, 2024: Journal of Xenobiotics
#5
Valentina Caputi, Lee Hill, Melanie Figueiredo, Jelena Popov, Emily Hartung, Kara Gross Margolis, Kanish Baskaran, Papiha Joharapurkar, Michal Moshkovich, Nikhil Pai
INTRODUCTION: Critical phases of neurodevelopment and gut microbiota diversification occur in early life and both processes are impacted by genetic and environmental factors. Recent studies have shown the presence of gut microbiota alterations in neurodevelopmental disorders. Here we performed a systematic review of alterations of the intestinal microbiota composition and function in pediatric and adult patients affected by autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and Rett syndrome (RETT)...
2024: Frontiers in Neuroscience
#6
JOURNAL ARTICLE
Matteo Bassetti, Daniele R Giacobbe, Christina Agvald-Ohman, Murat Akova, Ana Alastruey-Izquierdo, Sevtap Arikan-Akdagli, Elie Azoulay, Stijn Blot, Oliver A Cornely, Manuel Cuenca-Estrella, Dylan W de Lange, Francesco G De Rosa, Jan J De Waele, George Dimopoulos, Jose Garnacho-Montero, Martin Hoenigl, Souha S Kanj, Philipp Koehler, Bart J Kullberg, Frédéric Lamoth, Cornelia Lass-Flörl, Johan Maertens, Ignacio Martin-Loeches, Patricia Muñoz, Garyphallia Poulakou, Jordi Rello, Maurizio Sanguinetti, Fabio S Taccone, Jean-François Timsit, Antoni Torres, Jose A Vazquez, Joost Wauters, Erika Asperges, Andrea Cortegiani, Cecilia Grecchi, Ilias Karaiskos, Clément Le Bihan, Toine Mercier, Klaus L Mortensen, Maddalena Peghin, Chiara Rebuffi, Sofia Tejada, Antonio Vena, Valentina Zuccaro, Luigia Scudeller, Thierry Calandra
PURPOSE: The aim of this document was to develop standardized research definitions of invasive fungal diseases (IFD) in non-neutropenic, adult patients without classical host factors for IFD, admitted to intensive care units (ICUs). METHODS: After a systematic assessment of the diagnostic performance for IFD in the target population of already existing definitions and laboratory tests, consensus definitions were developed by a panel of experts using the RAND/UCLA appropriateness method...
March 21, 2024: Intensive Care Medicine
#7
JOURNAL ARTICLE
Nathan Keates, Farradeh Martin, Krysia Emily Waldock
PURPOSE: Functioning labels have been used in relation to autistic people and differentiating between support needs. The main purpose of our study was to identify perspectives regarding language about being autistic. In regard to themselves and functioning. Furthermore, we investigated the influential factor of community connectedness on use of language acceptability and functioning labels. METHODS: 516 autistic respondents completed our survey. We asked about demographic characteristics, how respondents would like autistic people to be termed in the survey, and their acceptability (person with autism, Aspergers, disorder, conditions, living with autism, autistic)...
March 20, 2024: Journal of Autism and Developmental Disorders
#8
JOURNAL ARTICLE
Erika Asperges, Jessica Bagnarino, Cinzia Ancarani, Ginevra Baggini, Matteo Filardo, Vincenzina Monzillo, Daniela Barbarini, Raffaele Bruno, Marco Paulli, Fausto Baldanti
No abstract text is available yet for this article.
March 11, 2024: International Journal of Infectious Diseases: IJID
#9
JOURNAL ARTICLE
Erika Asperges, Rebecca Pesare, Cecilia Bassoli, Matteo Calia, Sonia Lerta, Francesco Citiolo, Giuseppe Albi, Caterina Cavanna, Paolo Sacchi, Raffaele Bruno
Several criteria exist to diagnose pulmonary aspergillosis with varying degrees of certainty in specific populations, including oncohaematological patients (EORTC/MSG), ICU patients (mAspICU) and COVID-19 patients (ECMM). At the beginning of the pandemic, however, the diagnosis of COVID-19-Associated Pulmonary Aspergillosis (CAPA) could not be performed easily, and the decision to treat (DTT) was empirical. In this cross-sectional retrospective study including patients with SARS-CoV-2 infection and suspicion of CAPA, we studied the concordance between the DTT and the three diagnostic criteria using Cohen's coefficient, and then we identified the factors associated with the DTT and corrected them by treatment to study the influence of the diagnostic criteria on survival...
February 3, 2024: Antibiotics
#10
JOURNAL ARTICLE
Veronica R Villarreal, Maja Z Katusic, Scott M Myers, Amy L Weaver, James J Nocton, Robert G Voigt
OBJECTIVE: Determine the risk of autoimmune disease in research-identified cases of autism spectrum disorder (ASD) compared with referents using a longitudinal, population-based birth cohort. METHODS: ASD incident cases were identified from a population-based birth cohort of 31,220 individuals. Inclusive ASD definition based on DSM-IV-TR autistic disorder, Asperger syndrome, and pervasive developmental disorder, not otherwise specified, was used to determine ASD cases...
January 1, 2024: Journal of Developmental and Behavioral Pediatrics: JDBP
#11
JOURNAL ARTICLE
Johanna Wallensten, Gunnar Ljunggren, Anna Nager, Caroline Wachtler, Predrag Petrovic, Axel C Carlsson
The high prevalence of stress-related disorders and depression underscores the urgent need to unravel their impact on individual well-being. This study aim to investigate common psychiatric and stress-related diagnoses, along with postviral fatigue, in individuals with prior stress-induced exhaustion disorder (SED) and prior depression compared to those without prior SED or depression, and to study whether the psychiatric comorbidity patterns differ. The study includes individuals in Region Stockholm who, in 2011, did not have a diagnosis of SED or depression...
February 6, 2024: Journal of Affective Disorders
#12
JOURNAL ARTICLE
Sushmit Das, Reza Zomorrodi, Melissa Kirkovski, Aron T Hill, Peter G Enticott, Daniel M Blumberger, Tarek K Rajji, Pushpal Desarkar
Electroencephalogram (EEG) microstates, which represent quasi-stable patterns of scalp topography, are a promising tool that has the temporal resolution to study atypical spatial and temporal networks in autism spectrum disorder (ASD). While current literature suggests microstates are atypical in ASD, their clinical utility, i.e., relationship with the core behavioural characteristics of ASD, is not fully understood. The aim of this study was to examine microstate parameters in ASD, and examine the relationship between these parameters and core behavioural characteristics in ASD...
February 1, 2024: Progress in Neuro-psychopharmacology & Biological Psychiatry
#13
JOURNAL ARTICLE
Marga Vicedo
No abstract text is available yet for this article.
2024: Frontiers in Psychiatry
#14
JOURNAL ARTICLE
Veronica Nisticò, Gianmarco Ingrosso, Francesco Lombardi, Elia Chiudinelli, Giulia Bianchini, Raffaella Faggioli, Angelo Bertani, Orsola Gambini, Benedetta Demartini
PURPOSE: The relationship between autistic traits and eating disturbances has been given considerable attention over the last decades. The rise of a dimensional approach to psychopathology has expanded the way we think about autism, acknowledging that subthreshold autistic manifestations span across the general population and are more pronounced in psychiatric patients. Here we investigated the prevalence of eating disorders and its potential relationship with autistic traits and sensory sensitivity in a group of patients who were referred for the first time to a mental health outpatient clinic, without a formal diagnosis yet...
January 23, 2024: Eating and Weight Disorders: EWD
#15
JOURNAL ARTICLE
Melissa Harrington, Erika Busz, Amber Thor, M Katie Gardner, Kristen Carlin, Elaine Walsh
PURPOSE: The purpose of this quality improvement (QI) project was to develop and implement an assessment tool to identify a patient's specific needs due to autism spectrum disorder (ASD). The use of an individualized plan of care related to sensory and behavioral differences correlates with improved experiences in the perioperative setting for patients with ASD. DESIGN: Mixed methods, pre-post survey, retrospective data comparison. METHODS: Metrics planned to evaluate intervention outcomes included: (1) Comparison of pre and postsurvey data obtained from perioperative staff members following ASD education, (2) Evaluation of the number of behavior response team calls made compared to retrospective data, and (3) Survey response data from families assessing the perceived experience of perioperative stay...
January 12, 2024: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
#16
JOURNAL ARTICLE
Dheeraj Rai, Doug Webb, Amanda Lewis, Leonora Cotton, Jade Eloise Norris, Regi Alexander, David S Baldwin, Traolach Brugha, Madeleine Cochrane, Maria Chiara Del Piccolo, Emma J Glasson, Katherine K Hatch, David Kessler, Peter E Langdon, Helen Leonard, Stephanie J MacNeill, Nicola Mills, Maximiliano Vazquez Morales, Zoe Morgan, Raja Mukherjee, Alba X Realpe, Ailsa Russell, Sergio Starkstein, Jodi Taylor, Nicholas Turner, Joanna Thorn, Jack Welch, Nicola Wiles
BACKGROUND: Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed to manage anxiety in adults with an autism diagnosis. However, their effectiveness and adverse effect profile in the autistic population are not well known. This trial aims to determine the effectiveness and cost-effectiveness of the SSRI sertraline in reducing symptoms of anxiety and improving quality of life in adults with a diagnosis of autism compared with placebo and to quantify any adverse effects...
January 11, 2024: Trials
#17
JOURNAL ARTICLE
Boris Mention, Frederic Pourre, Julie Andanson
OBJECTIVES: Humor is essential to social relationships. Its use and understanding appear to be impaired in people with Autism Spectrum Disorder (ASD). The main objective was to review the existing literature on the detection, understanding and use of humor in persons with ASD. The secondary objective involved exploring assessment scales and specific intervention tools. METHODS: A systematic review of the literature was carried out on all available French and English scientific papers about humor - including irony - in persons with ASD up to November 2021...
January 3, 2024: L'Encéphale
#18
JOURNAL ARTICLE
Miyu Okabe, Yuki Miyamoto, Yuta Ikoma, Mikito Takahashi, Remina Shirai, Mutsuko Kukimoto-Niino, Mikako Shirouzu, Junji Yamauchi
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that includes autism, Asperger's syndrome, and pervasive developmental disorder. ASD is characterized by poor interpersonal relationships and strong attachment. The correlations between activated or inactivated gene products, which occur as a result of genetic mutations affecting neurons in ASD patients, and ASD symptoms are now of critical concern. Here, for the first time, we describe the process in which that the respective ASD-associated mutations (Arg676-to-Cys [R676C] and Ser951-to-Cys [S951C]) of semaphorin-5A (Sema5A) localize Sema5A proteins themselves around the plasma membrane in the N1E-115 cell line, a model line that can achieve neuronal morphological differentiation...
November 27, 2023: Pathophysiology: the Official Journal of the International Society for Pathophysiology
#19
JOURNAL ARTICLE
S Aghakhani, N Carre, K Mostovoy, R Shafer, K Baeza-Hernandez, G Entenberg, A Testerman, E L Bunge
BACKGROUND: Conversational agents (CA's) have shown promise in increasing accessibility to mental health resources. This study aimed to identify common themes of messages sent to a mental health CA (Wysa) related to ASD by general users and users that identify as having ASD. METHODS: This study utilized retrospective data. Two thematic analyses were conducted, one focusing on user messages including the keywords (e.g., ASD, autism, Asperger), and the second one with messages from users who self-identified as having ASD...
2023: Frontiers in digital health
#20
JOURNAL ARTICLE
Masayuki Ohira, Takashi Osada, Hiroaki Kimura, Terunori Sano, Masaki Takao
BACKGROUND: The characteristics of functional limb weakness (FLW) as one of the manifestations of functional neurological disorder after vaccination against coronavirus disease 2019 (COVID-19) remain controversial. METHODS: In this descriptive case series, we aimed to elucidate the characteristics of Japanese patients with FLW who claimed muscle weakness after COVID-19 vaccination among patients who visited our outpatient clinic between 1 June 2021 and 31 December 2022...
December 2023: ENeurologicalSci
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