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https://www.readbyqxmd.com/read/28523941/lifestyle-as-medicine-the-case-for-a-true-health-initiative
#1
David L Katz, Elizabeth P Frates, Jonathan P Bonnet, Sanjay K Gupta, Erkki Vartiainen, Richard H Carmona
The power of lifestyle as medicine was perceived thousands of years ago. There is now consistent and compelling science to support the important influence of lifestyle on health. Approximately 80% of chronic disease and premature death could be prevented by not smoking, being physically active, and adhering to a healthful dietary pattern. Cardiovascular disease, diabetes, stroke, dementia, and cancer are all influenced by lifestyle choices. Despite the ample evidence about what behaviors promote health, confusion still prevails among the general population...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/28495488/vascular-age-rr-ally-rally-and-vascular-speed-based-on-score-relations-between-new-concepts-of-cardiovascular-prevention
#2
José I Cuende
No abstract text is available yet for this article.
May 8, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28480802/optimization-of-fecal-cytology-in-the-dog-comparison-of-three-sampling-methods
#3
Petros S Frezoulis, Elisavet Angelidou, Anastasia Diakou, Timoleon S Rallis, Mathios E Mylonakis
Dry-mount fecal cytology (FC) is a component of the diagnostic evaluation of gastrointestinal diseases. There is limited information on the possible effect of the sampling method on the cytologic findings of healthy dogs or dogs admitted with diarrhea. We aimed to: (1) establish sampling method-specific expected values of selected cytologic parameters (isolated or clustered epithelial cells, neutrophils, lymphocytes, macrophages, spore-forming rods) in clinically healthy dogs; (2) investigate if the detection of cytologic abnormalities differs among methods in dogs admitted with diarrhea; and (3) investigate if there is any association between FC abnormalities and the anatomic origin (small- or large-bowel diarrhea) or the chronicity of diarrhea...
May 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28467284/clinical-topographical-anatomy-of-the-gastro-oesophageal-junction-in-the-cat
#4
Agni Voutsinou, Lysimachos G Papazoglou, Ioannis Antonopoulos, Timoleon S Rallis
Objectives The purpose of the present study was to describe histologically the gastro-oesophageal junction in the cat and interrelationships of this region. Our hypothesis was that cats are devoid of abdominal oesophagus. Methods Three centimetres of the terminal oesophagus, the phreno-oesophageal membrane with 1-2 cm margins of the diaphragmatic crural muscle and the proximal 3 cm of the gastric cardia were obtained from nine domestic shorthair cats and one domestic longhair cat that were euthanased for reasons other than digestive tract pathology...
May 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28446533/prognostic-evaluation-of-epidermal-growth-factor-receptor-egfr-genotype-and-phenotype-parameters-in-triple-negative-breast-cancers
#5
Sofia Levva, Vassiliki Kotoula, Ioannis Kostopoulos, Kyriaki Manousou, Christos Papadimitriou, Kyriaki Papadopoulou, Sotiris Lakis, Kyriakos Koukoulias, Vasilios Karavasilis, George Pentheroudakis, Eufemia Balassi, Flora Zagouri, Ioannis G Kaklamanos, Dimitrios Pectasides, Evangelia Razis, Gerasimos Aravantinos, Pavlos Papakostas, Dimitrios Bafaloukos, Grigorios Rallis, Helen Gogas, George Fountzilas
BACKGROUND: Epidermal growth factor receptor (EGFR) aberrations have been implicated in the pathogenesis of triple-negative breast cancer (TNBC) but their impact on prognosis and, therefore, druggability, remain controversial. Herein, we studied EGFR aberrations at different molecular levels and assessed their prognostic impact in patients with operable TNBC treated with adjuvant anthracycline-based chemotherapy. MATERIALS AND METHODS: We evaluated the prognostic impact of EGFR gene status by fluorescent in situ hybridization (FISH), EGFR coding mutations by Sanger and next-generation sequencing, relative EGFR messenger RNA (mRNA) levels by qPCR (upper quartile) and EGFR and p53 protein expression by immunohistochemistry (IHC), in 352 centrally-assessed tumors from an equal number of TNBC patients...
May 2017: Cancer Genomics & Proteomics
https://www.readbyqxmd.com/read/28435476/successful-treatment-of-bullous-lichen-planus-with-acitretin-monotherapy-review-of-treatment-options-for-bullous-lichen-planus-and-case-report
#6
Efstathios Rallis, Angeliki Liakopoulou, Constantinos Christodoulopoulos, Alexandros Katoulis
BACKGROUND: Bullous lichen planus (BLP) is a rare variant of lichen planus, characterized by the development of vesicular and bullous lesions, of skin, nails, hair and/or mucosa. MAIN OBSERVATIONS: We present a case of 63-year-old woman with BLP, unresponsive to previous therapies with topical corticosteroids, topical calcipotriol, antihistamines and oral cyclosporine (4 mg/kg/day for 4 months). She was already receiving treatment for arterial hypertension, hyperlipidemia, atrial fibrillation and uncontrolled diabetes mellitus...
December 31, 2016: Journal of Dermatological Case Reports
https://www.readbyqxmd.com/read/28415915/evaluation-of-dogs-with-macroscopic-haematuria-a-retrospective-study-of-162-cases-2003-2010
#7
K K Adamama-Moraitou, D Pardali, N N Prassinos, G Menexes, M N Patsikas, T S Rallis
AIMS: To retrospectively describe clinical features of dogs that were presented to a small animal clinic between 2003-10 with macroscopic haematuria, and investigate whether signalment of the dog and severity and duration of the haematuria at admission were associated with specific aetiologies. METHODS: Medical records were evaluated of 162 dogs with macroscopic haematuria admitted to a University-based small animal clinic in Thessaloniki, Greece, from January 2003 to December 2010...
May 3, 2017: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/28407387/gigging-benzene
#8
Quang H Luu, Tobias Fiedler, John A Gladysz
Go Aggies! Go Chemikers! The word "gig" applies to a multipronged metal tool for hunting frogs and fish. It constitutes part of a rallying cry, "gig 'em" that inspires Texas A&M Aggies to victory in athletic and academic competitions. This Highlight examines recent victories in the C....._ C cleavage of benzene made possible by a four-pronged iridium gig that yields a "spring-loaded" norbornadiene-like structure with significant ring strain.
April 13, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28400894/surgical-suturing-induced-melanocytic-nevi-a-new-type-of-eruptive-melanocytic-nevi
#9
Alexander C Katoulis, Dimitrios Sgouros, Giuseppe Argenziano, Efstathios Rallis, Ioannis Panayiotides, Dimitrios Rigopoulos
BACKGROUND: Nevogenesis is a complex process involving several pathogenetic mechanisms, including genetic factors, hormonal influences and UV-radiation. Trauma has been described as a triggering factor for an alternative pathway of nevogenesis. Eruptive melanocytic nevi (EMN), related either to immunosuppression or to blistering disorders, represent a special type of nevi probably induced by the disruption of the dermo-epidermal junction and consequent proliferation of quiescent pigment cells during re-epithelization...
November 30, 2016: Journal of Dermatological Case Reports
https://www.readbyqxmd.com/read/28374871/quality-of-life-measurements-for-patients-with-chronic-suppurative-otitis-media-italian-adaptation-of-chronic-ear-survey
#10
G Ralli, C Milella, M Ralli, M Fusconi, G La Torre
The chronic ear survey (CES) is a sensitive and disease specific quality of life (QoL) measurement tool in patients with chronic suppurative otitis media (CSOM). It is a 13-item survey that evaluates the frequency, duration and severity of problems associated with this disease. It is composed of three subscales that describe activity restrictions, symptoms and medical resource utilisation. Based on patient's answers, it is possible to obtain a score resulting in a scale ranging from 0 to 100; the highest indicates the best health, while the lowest denotes poor health...
February 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28355263/the-effect-of-a-sequential-structure-of-practice-for-the-training-of-perceptual-cognitive-skills-in-tennis
#11
David P Broadbent, Paul R Ford, Dominic A O'Hara, A Mark Williams, Joe Causer
OBJECTIVE: Anticipation of opponent actions, through the use of advanced (i.e., pre-event) kinematic information, can be trained using video-based temporal occlusion. Typically, this involves isolated opponent skills/shots presented as trials in a random order. However, two different areas of research concerning representative task design and contextual (non-kinematic) information, suggest this structure of practice restricts expert performance. The aim of this study was to examine the effect of a sequential structure of practice during video-based training of anticipatory behavior in tennis, as well as the transfer of these skills to the performance environment...
2017: PloS One
https://www.readbyqxmd.com/read/28352245/listening-and-hearing-a-voice-hearer-s-invitation-into-relationship
#12
Berta Britz
Although historically overlooked, empirical links between trauma and psychosis have received growing attention over the past decade. Increasingly, clinical researchers have also zeroed in on the role that distressing or traumatic life events play in the psychosocial formation and maintenance of psychosis. This paper re-locates anomalous experiences in their human contexts, and asks that clinicians and researchers engage with these contexts. The author shares a first person account of her experience changing her relationships with dominance in order to reclaim and accept her human being-ness, a reorientation supported by her involvement in the world hearing voices network movement and community...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28345423/systemic-lupus-erythematosus-and-hearing-disorders-literature-review-and-meta-analysis-of-clinical-and-temporal-bone-findings
#13
Arianna Di Stadio, Massimo Ralli
Objective This literature review and meta-analysis was performed to evaluate the correlations among hearing and vestibular clinical symptoms, temporal bone findings, and pathological mechanisms in patients with systemic lupus erythematosus (SLE). Study design Relevant papers in the literature were retrospectively reviewed. Clinical hearing aspects in patients with SLE and relevant temporal bone studies in the same field were analyzed. Methods PubMed and Google Scholar searches were performed using the following keywords: "auto-immune disease," "systemic lupus erythematosus (SLE)," "hearing loss," "temporal bone study," "vertigo," "dizziness," "tinnitus," "ear symptoms," "treatment," "diagnosis," "symptoms," "etiopathogenesis," "Wegener granulomatosis," "Sjogren," "polyarteritis nodosa," "Cogan syndrome," and "granulomatosis...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28282015/relying-on-the-national-mobile-disaster-hospital-as-a-business-continuity-strategy-in-the-aftermath-of-a-tornado-the-louisville-experience
#14
Randy D Kearns, Lew Stringer, James Craig, Regina Godette-Crawford, Paul S Black, David L Andra, James Winslow
On 28th April, 2014, a tornado left much of Louisville, MS and the local hospital, Winston Medical Center, in ruin. In the USA, temporary hospital solutions have been used to augment the mainstream healthcare system since the American Civil War. As memories fade, however, the necessary readiness for a temporary hospital also fades, at times leaving a patchwork of resources either underfunded or abandoned. With the creation of the Hospital Preparedness Program, several temporary hospital solutions were created in various states across the USA...
January 1, 2017: Journal of Business Continuity & Emergency Planning
https://www.readbyqxmd.com/read/28281664/genetic-interactions-and-functional-analyses-of-the-fission-yeast-gsk3-and-amk2-single-and-double-mutants-defective-in-torc1-dependent-processes
#15
Charalampos Rallis, StJohn Townsend, Jürg Bähler
The Target of Rapamycin (TOR) signalling network plays important roles in aging and disease. The AMP-activated protein kinase (AMPK) and the Gsk3 kinase inhibit TOR during stress. We performed genetic interaction screens using synthetic genetic arrays (SGA) with gsk3 and amk2 as query mutants, the latter encoding the regulatory subunit of AMPK. We identified 69 negative and 82 positive common genetic interactors, with functions related to cellular growth and stress. The 120 gsk3-specific negative interactors included genes functioning in translation and ribosomes...
March 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28273485/clinical-factors-of-response-in-patients-with-advanced-ovarian-cancer-participating-in-early-phase-clinical-trials
#16
Angela George, Rebecca Kristeleit, Saeed Rafii, Caroline O Michie, Rebecca Bowen, Vasiliki Michalarea, Tom van Hagen, Mabel Wong, Grigorios Rallis, L Rhoda Molife, Juanita Lopez, Udai Banerji, Susana N Banerjee, Martin E Gore, Johann S de Bono, Stan B Kaye, Timothy A Yap
Drug resistance to conventional anticancer therapies is almost inevitable in patients with advanced ovarian cancer (AOC), limiting their available treatment options. Novel phase I trial therapies within a dedicated drug development unit may represent a viable alternative; however, there is currently little evidence for patient outcomes in such patients. To address this, we undertook a retrospective review of patients with AOC allocated to phase I trials in the Drug Development Unit at Royal Marsden Hospital (RMH) between June 1998 and October 2010...
March 5, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28267726/trump-s-pick-rallies-biosimilar-makers
#17
(no author information available yet)
No abstract text is available yet for this article.
March 7, 2017: Nature Biotechnology
https://www.readbyqxmd.com/read/28253438/collaboration-among-sectors-to-increase-pulse-consumption
#18
Julianne Curran, Milla McLachlan, Richard Black, Irv Widders, Mark Manary
The United Nations declaration of 2016 as the International Year of Pulses (IYP) provided an unprecedented opportunity to showcase pulses on the global stage for their contribution to affordable nutrition, health, and sustainability. Despite the IYP's successes in stakeholder engagement, continuing to foster and strengthen partnerships and collaborations is necessary to meet the IYP goals of increased pulse production and consumption for human benefit. Shifting consumer behavior to increase pulse consumption emerged during IYP meetings as a shared priority for all stakeholders...
March 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28230665/it-s-time-to-earn-the-public-s-trust
#19
Maureen Shawn Kennedy
As the most trusted profession, will nursing rally to safeguard access to care?
March 2017: American Journal of Nursing
https://www.readbyqxmd.com/read/28222847/relying-on-the-national-mobile-disaster-hospital-as-a-business-continuity-strategy-in-the-aftermath-of-a-tornado-the-louisville-experience
#20
Randy D Kearns, Lew Stringer, James Craig, Regina Godette-Crawford, Paul S Black, David L Andra, James Winslow
On 28th April, 2014, a tornado left much of Louisville, MS and the local hospital, Winston Medical Center, in ruin. In the USA, temporary hospital solutions have been used to augment the mainstream healthcare system since the American Civil War. As memories fade, however, the necessary readiness for a temporary hospital also fades, at times leaving a patchwork of resources either underfunded or abandoned. With the creation of the Hospital Preparedness Program, several temporary hospital solutions were created in various states across the USA...
January 1, 2017: Journal of Business Continuity & Emergency Planning
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