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Ultra MIS

Gautam Nayar, Daniel J Blizzard, Timothy Y Wang, Steven Cook, Adam G Back, David Vincent, Isaac O Karikari
OBJECTIVE A previous study found that ultra-low radiation imaging (ULRI) with image enhancement significantly decreases radiation exposure by roughly 75% for both the patient and operating room personnel during minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) (p < 0.001). However, no clinical data exist on whether this imaging modality negatively impacts patient outcomes. Thus, the goal of this randomized controlled trial was to assess pedicle screw placement accuracy with ULRI with image enhancement compared with conventional, standard-dose fluoroscopy for patients undergoing single-level MIS-TLIF...
February 2018: Journal of Neurosurgery. Spine
Negussie Alula Bekele, Worknehe Agegnehu Abebe, Jemal Zeberga Shifa
Percutaneous Central Venous Catheter (CVC) insertion using internal jugular and Subclavian veins routes is common procedure for all intensive care admitted patients and some patients in the ward as demand arises in central and referral hospitals of Botswana. This is a case report of a patient on whom a third attempt of re-inserting a CVC for fluid and total parenteral nutrition (TPN) was made. X-ray showed that left Subclavian inserted catheter was mis-directed to internal jugular vein of the same side creating discomfort to the patient...
2017: Pan African Medical Journal
C Rossitto, S Cianci, S Gueli Alletti, E Perrone, S Pizzacalla, G Scambia
OBJECTIVES: During the last decade endoscopic surgical procedures have been constantly evolving. The latest innovation in ultra-minimally invasive surgery (MIS) is the percutaneous technology (Percuvance™ Percutaneous Surgical System (PSS), Teleflex Inc., USA). We compared surgical outcome of hysterectomy, in a retrospective cohort study using the most recent MIS techniques as single-site (LESS) surgery, 3mm laparoscopy (MiniLPS) and percutaneous system (PSS) with standard laparoscopy (LPS)...
September 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Timothy Y Wang, S Harrison Farber, Scott S Perkins, Adam G Back, Sarah A Byrd, Debbie Chi, David Vincent, Isaac O Karikari
STUDY DESIGN: Randomized controlled trial. OBJECTIVE: To compare radiation exposure between ultra-low radiation imaging (ULRI) with image enhancement and standard-dose fluoroscopy for patients undergoing minimally invasive transforaminal lumbar interbody fusion (MIS TLIF). SUMMARY OF BACKGROUND DATA: Although the benefits of MIS are lauded by many, there is a significant amount of radiation exposure to surgeon and operating room personnel...
February 15, 2017: Spine
Solomon Kamson, Andrea M Trescot, Paul D Sampson, Yiyi Zhang
BACKGROUND: Minimally invasive surgery (MIS) technique is becoming the standard tissue sparing approach for decompression of lumbar central and lateral recess stenosis, intervertebral disc herniation, or any situation that would have required extensive open decompression laminectomy. Full-endoscopic or arthroscopic assisted surgery is arguably the "ultra-MIS" approach to lumbar spinal pathology. Age and body mass index (BMI) are significant risk factors to be considered in full-endoscopic assisted ultra-MIS...
February 2017: Pain Physician
Ikbal Sencan, Brendan K Huang, Yong Bian, Emily Mis, Mustafa K Khokha, Hui Cao, Michael Choma
We developed ultra-high-speed, phase-sensitive, full-field reflection interferometric confocal microscopy (FFICM) for the quantitative characterization of in vivo microscale biological motions and flows. We demonstrated 2D frame rates in excess of 1 kHz and pixel throughput rates up to 125 MHz. These fast FFICM frame rates were enabled by the use of a low spatial coherence, high-power laser source. Specifically, we used a dense vertical cavity surface emitting laser (VCSEL) array that synthesized low spatial coherence light through a large number of narrowband, mutually-incoherent emitters...
November 1, 2016: Biomedical Optics Express
Vladyslav S Bondarenko, Mikhail S Gelfand
A typical eukaryotic gene is comprised of alternating stretches of regions, exons and introns, retained in and spliced out a mature mRNA, respectively. Although the length of introns may vary substantially among organisms, a large fraction of genes contains short introns in many species. Notably, some Ciliates (Paramecium and Nyctotherus) possess only ultra-short introns, around 25 bp long. In Paramecium, ultra-short introns with length divisible by three (3n) are under strong evolutionary pressure and have a high frequency of in-frame stop codons, which, in the case of intron retention, cause premature termination of mRNA translation and consequent degradation of the mis-spliced mRNA by the nonsense-mediated decay mechanism...
2016: PloS One
Timothy Y Wang, S Harrison Farber, Scott S Perkins, Adam G Back, Sarah A Byrd, Debbie Chi, David Vincent, Isaac O Karikari
STUDY DESIGN: Randomized controlled trial OBJECTIVE.: Compare radiation exposure between ultra-low radiation imaging (ULRI) with image enhancement and standard-dose fluoroscopy for patients undergoing minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) SUMMARY OF BACKGROUND DATA.: While the benefits of MIS are lauded by many, there is a significant amount of radiation exposure to surgeon and operating room (OR) personnel. Our goal with this work was to see if by using ultra-low dose radiation settings coupled with image enhancement, this exposure could be minimized...
May 31, 2016: Spine
Anders Ståhlberg, Paul M Krzyzanowski, Jennifer B Jackson, Matthew Egyud, Lincoln Stein, Tony E Godfrey
Detection of cell-free DNA in liquid biopsies offers great potential for use in non-invasive prenatal testing and as a cancer biomarker. Fetal and tumor DNA fractions however can be extremely low in these samples and ultra-sensitive methods are required for their detection. Here, we report an extremely simple and fast method for introduction of barcodes into DNA libraries made from 5 ng of DNA. Barcoded adapter primers are designed with an oligonucleotide hairpin structure to protect the molecular barcodes during the first rounds of polymerase chain reaction (PCR) and prevent them from participating in mis-priming events...
June 20, 2016: Nucleic Acids Research
Hyun Jeong, Hye Min Oh, Seungho Bang, Hyeon Jun Jeong, Sung-Jin An, Gang Hee Han, Hyun Kim, Seok Joon Yun, Ki Kang Kim, Jin Cheol Park, Young Hee Lee, Gilles Lerondel, Mun Seok Jeong
We present a novel metal-insulator-semiconductor (MIS) diode consisting of graphene, hexagonal BN, and monolayer MoS2 for application in ultrathin nanoelectronics. The MIS heterojunction structure was fabricated by vertically stacking layered materials using a simple wet chemical transfer method. The stacking of each layer was confirmed by confocal scanning Raman spectroscopy and device performance was evaluated using current versus voltage (I-V) and photocurrent measurements. We clearly observed better current rectification and much higher current flow in the MIS diode than in the p-n junction and the metal-semiconductor diodes made of layered materials...
March 9, 2016: Nano Letters
D Batouche, K Elhalimi, S Abassini, N Benatta, H Messali, N Chaib, M Negadi, Z Mentouri
OBJECTIFS: L'objectif est de fournir les informations spécifiques d'un orage adrénergique lors d'un stress violent chez l'enfant. MéTHODES: 2 observations cliniques chez des enfants ayant subi un traumatisme violent. RéSULTATS: 1(er) cas : CA 12 ans, admis en réanimation pédiatrique pour une noyade stade3, le 2 août 2015. Il a été intubé, sédaté ventilé en auto-contrôle, avec une peep à 7. Une administration de la noradrénaline à 0,2 gamma/kg/min pour optimiser les pressions artérielles moyennes (PAM) qui restaient stables aux alentours de 88mmHg...
December 2015: Annales de Cardiologie et D'angéiologie
Tim Jäger, Claudia Scherr, Devika Shah, Vera Majewsky, Ursula Wolf, Lucietta Betti, Stephan Baumgartner
OBJECTIVES: The objective was to evaluate homeopathic basic research studies that use plant-based bioassays. With this in view, a compilation was made of the findings of three systematic literature reviews covering plant-based bioassays in the three fields of healthy, abiotically, or biotically stressed plants. This compilation focused on investigations using advanced experimental methods and detailed descriptions, also with the aim of supporting the design of future experiments. METHODS: Publications included had to report on studies into the effects of homeopathic preparations on whole plants, seeds, plant parts and cells...
October 2015: Homeopathy: the Journal of the Faculty of Homeopathy
Sarah A Sabatinos, Nimna S Ranatunga, Ji-Ping Yuan, Marc D Green, Susan L Forsburg
DNA replication stress causes genome mutations, rearrangements, and chromosome missegregation, which are implicated in cancer. We analyze a fission yeast mutant that is unable to complete S phase due to a defective subunit of the MCM helicase. Despite underreplicated and damaged DNA, these cells evade the G2 damage checkpoint to form ultrafine bridges, fragmented centromeres, and uneven chromosome segregations that resembles micronuclei. These micronuclei retain DNA damage markers and frequently rejoin with the parent nucleus...
October 1, 2015: Molecular Biology of the Cell
Jerzy Garcarek, Jacek Kurcz, Maciej Guziński, Mirosław Banasik, Marcin Miś, Tomasz Gołębiowski
BACKGROUND: High volume of intravenous contrast in CT-angiography may result in contrast-induced nephropathy. Intraarterial ultra-low volume of contrast medium results in its satisfactory blood concentration with potentially good image quality. The first main purpose was to assess the influence of the method on function of transplanted kidney in patients with impaired graft function. The second main purpose of the study was to evaluate the usefulness of this method for detection of gastrointestinal and head-and-neck haemorrhages...
2015: Polish Journal of Radiology
Sen Wang, Jiedan Chen, Wenpan Zhang, Yan Hu, Lijing Chang, Lei Fang, Qiong Wang, Fenni Lv, Huaitong Wu, Zhanfeng Si, Shuqi Chen, Caiping Cai, Xiefei Zhu, Baoliang Zhou, Wangzhen Guo, Tianzhen Zhang
BACKGROUND: SNPs are the most abundant polymorphism type, and have been explored in many crop genomic studies, including rice and maize. SNP discovery in allotetraploid cotton genomes has lagged behind that of other crops due to their complexity and polyploidy. In this study, genome-wide SNPs are detected systematically using next-generation sequencing and efficient SNP genotyping methods, and used to construct a linkage map and characterize the structural variations in polyploid cotton genomes...
2015: Genome Biology
A Capa-Grasa, J M Rojo-Manaute, F C Rodríguez, J V Martín
BACKGROUND: Authors have reported better outcomes, by reducing surgical dissection for carpal tunnel syndromes requiring surgery. Recently, a new sonographically guided technique for ultra minimally invasive (Ultra-MIS) carpal tunnel release (CTR) through 1mm incision has been described. HYPOTHESIS: We hypothesized that a clinical trial for comparing Ultra-MIS versus Mini-open Carpal Tunnel Release (Mini-OCTR) was feasible. MATERIALS AND METHODS: To test our hypothesis, we conducted a pilot study for studying Ultra-MIS versus Mini-OCTR respectively performed through a 1mm or a 2 cm incision...
May 2014: Orthopaedics & Traumatology, Surgery & Research: OTSR
Franco Canestri
OBJECTIVE: This article describes a mathematical approach to identifying the absolute shortest laser optical focusing head f(min) associated with the smallest not-to-exceed ablative crater radius and depth to be used during ultra-conservative minimally invasive surgery (UCMIS) procedures with pulsed CO(2) lasers. This value is important because it allows forecasting the micro-boundary ablative conditions of a laser device implemented in the operating room (OR) in conjunction with minimally invasive tools...
November 2011: Photomedicine and Laser Surgery
Tobias Frauenrath, Fabian Hezel, Wolfgang Renz, Thibaut de Geyer d'Orth, Matthias Dieringer, Florian von Knobelsdorff-Brenkenhoff, Marcel Prothmann, Jeanette Schulz Menger, Thoralf Niendorf
BACKGROUND: To demonstrate the applicability of acoustic cardiac triggering (ACT) for imaging of the heart at ultrahigh magnetic fields (7.0 T) by comparing phonocardiogram, conventional vector electrocardiogram (ECG) and traditional pulse oximetry (POX) triggered 2D CINE acquisitions together with (i) a qualitative image quality analysis, (ii) an assessment of the left ventricular function parameter and (iii) an examination of trigger reliability and trigger detection variance derived from the signal waveforms...
2010: Journal of Cardiovascular Magnetic Resonance
Marzio Angelo Zullo, Alfonso Ruggiero, Roberto Montera, Francesco Plotti, Ludovico Muzii, Roberto Angioli, Pierluigi Benedetti Panici
OBJECTIVE: To evaluate use of bulking agents (polydimethylsiloxane) as an alternative treatment of female stress urinary incontinence (SUI) in older patients. STUDY DESIGN: Prospective cohort study. MAIN OUTCOME MEASURES: Women with age >75 years old, affected by stress urinary incontinence, presenting to our institution between January 2005 and January 2008 were considered for eligibility in this prospective study. All patients were submitted to transurethral implantation using Macroplastique Implantation System (MIS) (Uroplasty, Minneapolis, Minnesota)...
March 2010: Maturitas
Zhenbin Chen, Jinong Feng, Carolyn H Buzin, Qiang Liu, Lawrence Weiss, Kemp Kernstine, George Somlo, Steve S Sommer
BACKGROUND: Tumor DNA has been shown to be present both in circulating tumor cells in blood and as fragments in the plasma of metastatic cancer patients. The identification of ultra-rare tumor-specific mutations in blood would be the ultimate marker to measure efficacy of cancer therapy and/or early recurrence. Herein we present a method for detecting microinsertions/deletions/indels (MIDIs) at ultra-high analytical selectivity. MIDIs comprise about 15% of mutations. METHODS AND FINDINGS: We describe MIDI-Activated Pyrophosphorolysis (MAP), a method of ultra-high analytical selectivity for detecting MIDIs...
September 28, 2009: PloS One
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