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https://www.readbyqxmd.com/read/29302294/severe-tetracycline-dental-discoloration-restoration-with-conventional-feldspathic-ceramic-veneers-a-clinical-report
#1
Vicente Faus-Matoses, Ignacio Faus-Matoses, Esther Ruiz-Bell, Vicente J Faus-Llácer
The treatment of severe tetracycline discoloration is a challenge for the dentist. There are several treatment options and one of the most effective is the use of feldspathic veneers. The aim of this clinical case was to carry out the replacement with conventional feldspathic ceramic veneers on a patient with highly stained teeth (grade IV tetracycline) by a minimally invasive approach. Clinical examination revealed gingival retraction, color change of the veneers, ceramic cracked of 1.1 and 1.3 and incisal wear in lower anterior teeth...
November 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29234531/ultra-mini-percutaneous-nephrolithotomy-pcnl-versus-standard-pcnl-a-randomised-clinical-trial
#2
Ramin Haghighi, Hossein Zeraati, Maryam Ghorban Zade
Objective: To assess the effectiveness and advantages of ultra-mini-percutaneous nephrolithotomy (UM-PCNL) versus standard PCNL (S-PCNL), as one of the most important differences between the various PCNL techniques is the size of the renal access, which contributes to the broad spectrum of complications and outcomes. Patients and methods: This clinical randomised trial was conducted in 2016. In all, 70 patients with renal or upper ureteric stones of 10-20 mm in diameter, who were candidates for PCNL, were divided equally into two groups...
December 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29220192/fluidic-microactuation-of-flexible-electrodes-for-neural-recording
#3
Flavia Vitale, Daniel Vercosa, Alexander V Rodriguez, Sushma Sri Pamulapati, Frederik Seibt, Eric Lewis, Jiaxi Stephen Yan, Krishna Badhiwala, Mohammed Adnan, Gianni Royer-Carfagni, Michael Beierlein, Caleb Kemere, Matteo Pasquali, Jacob Robinson
Soft and conductive nanomaterials like carbon nanotubes, graphene, and nanowire scaffolds have expanded the family of ultra-flexible microelectrodes that can bend and flex with the natural movement of the brain, reduce the inflammatory response and improve the stability of long-term neural recordings. However, current methods to implant these highly flexible electrodes rely on temporary stiffening agents that temporarily increase the electrode size and stiffness thus aggravating neural damage during implantation, which can lead to cell loss and glial activation that persists even after the stiffening agents are removed or dissolve...
December 8, 2017: Nano Letters
https://www.readbyqxmd.com/read/29218393/-microperc-micropercutaneous-nephrolithotomy-a-review-of-the-literature
#4
REVIEW
Arvind P Ganpule, Jaspreet Chabra, Mahesh R Desai
Recent years have seen innovations in working armamentarium of percutaneous nephrolithotomy (PCNL) leading to development of novel modifications such as miniperc, ultra miniperc, and microperc. Amongst these microperc appears to be least invasive and various authors, off late, have reported their experience with the technique. Literature on microperc was reviewed by a MEDLINE/PubMed search with articles in the English language since 2011 in published peer-reviewed journals. Articles comprised of case series, comparative, and noncomparative studies...
December 7, 2017: Urolithiasis
https://www.readbyqxmd.com/read/29192879/pedicle-screw-placement-accuracy-using-ultra-low-radiation-imaging-with-image-enhancement-versus-conventional-fluoroscopy-in-minimally-invasive-transforaminal-lumbar-interbody-fusion-an-internally-randomized-controlled-trial
#5
Gautam Nayar, Daniel J Blizzard, Timothy Y Wang, Steven Cook, Adam G Back, David Vincent, Isaac O Karikari
OBJECTIVE A previous study found that ultra-low radiation imaging (ULRI) with image enhancement significantly decreases radiation exposure by roughly 75% for both the patient and operating room personnel during minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) (p < 0.001). However, no clinical data exist on whether this imaging modality negatively impacts patient outcomes. Thus, the goal of this randomized controlled trial was to assess pedicle screw placement accuracy with ULRI with image enhancement compared with conventional, standard-dose fluoroscopy for patients undergoing single-level MIS-TLIF...
December 1, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29190359/dna-terminal-structure-mediated-enzymatic-reaction-for-ultra-sensitive-discrimination-of-single-nucleotide-variations-in-circulating-cell-free-dna
#6
Tongbo Wu, Wei Chen, Ziyu Yang, Haocheng Tan, Jiayu Wang, Xianjin Xiao, Mengyuan Li, Meiping Zhao
Sensitive detection of the single nucleotide variants in cell-free DNA (cfDNA) may provide great opportunity for minimally invasive diagnosis and prognosis of cancer and other related diseases. Here, we demonstrate a facile new strategy for quantitative measurement of cfDNA mutations at low abundance in the cancer patients' plasma samples. The method takes advantage of a novel property of lambda exonuclease which effectively digests a 5'-fluorophore modified dsDNA with a 2-nt overhang structure and sensitively responds to the presence of mismatched base pairs in the duplex...
November 28, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29174441/hollow-microneedle-mediated-micro-injections-of-a-liposomal-hpv-e743-63-synthetic-long-peptide-vaccine-for-efficient-induction-of-cytotoxic-and-t-helper-responses
#7
Koen van der Maaden, Jeroen Heuts, Marcel Camps, Maria Pontier, Anton Terwisscha van Scheltinga, Wim Jiskoot, Ferry Ossendorp, Joke Bouwstra
Recent studies have shown that intradermal vaccination has great potential for T cell-mediated cancer immunotherapy. However, classical intradermal immunization with a hypodermic needle and syringe has several drawbacks. Therefore, in the present study a digitally controlled hollow microneedle injection system (DC-hMN-iSystem) with an ultra-low dead volume was developed to perform micro-injections (0.25-10μL) into skin in an automated manner. A synthetic long peptide derived from human papilloma virus formulated in cationic liposomes, which was used as a therapeutic cancer vaccine, was administered intradermally by using the DC-hMN-iSystem...
November 22, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29115844/scalable-fabrication-framework-of-implantable-ultrathin-and-flexible-probes-with-biodegradable-sacrificial-layers
#8
Xiangbing Jiao, Yuan Wang, Quan Qing
For long-term biocompatibility and performance, implanted probes need to further reduce their size and mechanical stiffness to match that of the surrounding cells, which, however, makes accurate and minimally invasive insertion operations difficult due to lack of rigidity and brings additional complications in assembling and surgery. Here, we report a scalable fabrication framework of implantable probes utilizing biodegradable sacrificial layers to address this challenge. Briefly, the integrated biodegradable sacrificial layer can dissolve in physiological fluids shortly after implantation, which allows the in situ formation of functional ultrathin film structures off of the initial small and rigid supporting backbone...
November 15, 2017: Nano Letters
https://www.readbyqxmd.com/read/29062456/effect-of-an-8k-ultra-high-definition-television-system-in-a-case-of-laparoscopic-gynecologic-surgery
#9
Yoichi Aoki, Masahiko Matsuura, Toshio Chiba, Hiromasa Yamashita
Various endoscopic devices have been developed for advanced minimally invasive surgery. We recently applied a new 8K ultra-high-definition television system during laparoscopic treatment of endometriosis. The procedure, which is described in detail, stands as the first reported application of an 8K ultra-high-definition system for laparoscopic gynecologic surgery. Comparison is made between depiction of the lesion by the new system and depiction by a full high-definition system. Improved diagnostic accuracy resulted from the increased image resolution, and we believe that this and other advantages will lead to widespread acceptance and further application of 8K ultra-high-definition systems in the field of gynecologic surgery...
September 2017: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/28968296/sentinel-lymph-node-ultra-staging-as-a-supplement-for-endometrial-cancer-intraoperative-frozen-section-deficiencies
#10
Morgan Blakely, Yuxin Liu, Jamal Rahaman, Monica Prasad-Hayes, Mikhail Tismenetsky, Xiaofei Wang, Navya Nair, Karen A Dresser, Nimesh Nagarsheth, Tamara Kalir
For endometrial cancer (EC), most surgeons rely on intraoperative frozen section (IFS) to determine the risk of nodal metastasis and necessity of lymphadenectomy. IFS remains a weak link in this practice due to its susceptibility to diagnostic errors. As a less invasive alternative, sentinel lymph node (SLN) mapping and ultra-staging have gradually gained acceptance for EC. We aimed to establish the SLN success rate, negative predictive value, and whether SLNs provide useful information for cases misdiagnosed on IFS...
September 29, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28923870/associations-between-voriconazole-therapeutic-drug-monitoring-toxicity-and-outcome-in-liver-transplant-patients-an-observational-study
#11
Zahra Hashemizadeh, Parisa Badiee, Seyed Ali Malekhoseini, Hadi Raeisi Shahraki, Bita Geramizadeh, Hashem Montaseri
The aim of this study was to investigate the variability of voriconazole plasma level and its relationship with clinical outcomes and adverse events, among liver transplant recipients to optimize the efficacy and safety of their treatment. Liver transplant recipients treated with voriconazole were included and voriconazole trough levels were quantified by the validated high-performance liquid chromatography method. Cytochrome P450 genotypes of CYP2C19 were evaluated in allograft liver tissues. A total of 832 voriconazole trough levels from 104 patients were measured...
September 18, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28875449/an-extracorporeal-carbon-dioxide-removal-ecco2r-device-operating-at-hemodialysis-blood-flow-rates
#12
R Garrett Jeffries, Laura Lund, Brian Frankowski, William J Federspiel
BACKGROUND: Extracorporeal carbon dioxide removal (ECCO2R) systems have gained clinical appeal as supplemental therapy in the treatment of acute and chronic respiratory injuries with low tidal volume or non-invasive ventilation. We have developed an ultra-low-flow ECCO2R device (ULFED) capable of operating at blood flows comparable to renal hemodialysis (250 mL/min). Comparable operating conditions allow use of minimally invasive dialysis cannulation strategies with potential for direct integration to existing dialysis circuitry...
September 6, 2017: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/28862876/quantification-of-cotinine-in-dried-blood-spots-as-a-biomarker-of-exposure-to-tobacco-smoke
#13
Daniel Ladror, Bruce Pitt, William Funk
OBJECTIVE: We present an ultra-sensitive, minimally-invasive method for quantifying cotinine in dried blood spot (DBS) samples as a biomarker of exposure to tobacco smoke that can be collected using a simple heel or finger prick to obtain blood samples. METHODS: Cotinine levels were measured in matched plasma and reconstituted DBS samples from smokers and nonsmokers to evaluate assay parameters. In addition, we applied this new method to finger-prick DBS samples that were collected from infants, children and young adults ages 1-21 to estimate exposure to tobacco smoke...
September 18, 2017: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/28839475/the-coronal-tooth-fractures-preliminary-evaluation-of-a-three-year-follow-up-of-the-anterior-teeth-direct-fragment-reattachment-technique-without-additional-preparation
#14
Lo Giudice G, Alibrandi A, Lipari F, Lizio A, Lauritano F, Cervino G, Cicciù M
OBJECTIVE: The aim of this research is to describe and to analyse the long-term results and the clinical steps of direct fragment reattachment technique with no additional tooth preparation, used to treat crown fracture. This technique achieves the clinical success, combining satisfactory aesthetic and functional results with a minimally invasive approach. METHODS: The 3 years follow-up included 9 patients (5 males, 4 females) with coronal fracture. In all the cases the fragment was available and intact...
2017: Open Dentistry Journal
https://www.readbyqxmd.com/read/28807248/tumor-model-for-surgical-simulation-to-assess-a-minimally-invasive-endoscopic-approach-for-midcheek-mass-removal
#15
Giovanni Dell' Aversana Orabona, Antonio Romano, Paola Bonavolontà, Vincenzo Abbate, Alfonso Manfuso, Giorgio Iaconetta, Bernhard Hirt, Luigi Califano
INTRODUCTION: The midcheek is considered one of the most important facial area due to its involvement in mimic expression and communication. Pathology of this district is complex due to the variety of soft tissue belonging to the face. We propose a surgical simulation, to assess the feasibility of a new minimally invasive endoscopic approach for midcheek mass removal. TECHNICAL REPORT: This study was performed on four cadavers, at the Anatomy Laboratory of the University of Tubingen...
September 2017: Surgical Oncology
https://www.readbyqxmd.com/read/28753500/laparoscopic-minilaparoscopic-single-port-and-percutaneous-hysterectomy-comparison-of-perioperative-outcomes-of-minimally-invasive-approaches-in-gynecologic-surgery
#16
C Rossitto, S Cianci, S Gueli Alletti, E Perrone, S Pizzacalla, G Scambia
OBJECTIVES: During the last decade endoscopic surgical procedures have been constantly evolving. The latest innovation in ultra-minimally invasive surgery (MIS) is the percutaneous technology (Percuvance™ Percutaneous Surgical System (PSS), Teleflex Inc., USA). We compared surgical outcome of hysterectomy, in a retrospective cohort study using the most recent MIS techniques as single-site (LESS) surgery, 3mm laparoscopy (MiniLPS) and percutaneous system (PSS) with standard laparoscopy (LPS)...
September 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28720368/a-critical-review-of-miniaturised-percutaneous-nephrolithotomy-is-smaller-better
#17
REVIEW
Silvia Proietti, Guido Giusti, Mahesh Desai, Arvind P Ganpule
CONTEXT: In an effort to reduce morbidity related to percutaneous nephrolithotomy (PCNL), some investigators have progressively introduced miniaturised approaches. The development of miniaturised nephroscopes facilitated widespread dissemination of these techniques and a significant expansion of the role of PCNL in endourology. OBJECTIVE: To discuss the different techniques comprising modern PCNL and identify the pros and cons of each of them. EVIDENCE ACQUISITION: Data for this review were identified through a search of PubMed, including studies published in the last 20 yr in core clinical journals in English...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28663850/multimodal-evaluation-of-ultra-short-laser-pulses-treatment-for-skin-burn-injuries
#18
Moises Oliveira Dos Santos, Anne Latrive, Pedro Arthur Augusto De Castro, Wagner De Rossi, Telma Maria Tenorio Zorn, Ricardo Elgul Samad, Anderson Zanardi Freitas, Carlos Lenz Cesar, Nilson Dias Vieira Junior, Denise Maria Zezell
Thousands of people die every year from burn injuries. The aim of this study is to evaluate the feasibility of high intensity femtosecond lasers as an auxiliary treatment of skin burns. We used an in vivo animal model and monitored the healing process using 4 different imaging modalities: histology, Optical Coherence Tomography (OCT), Second Harmonic Generation (SHG), and Fourier Transform Infrared (FTIR) spectroscopy. 3 dorsal areas of 20 anesthetized Wistar rats were burned by water vapor exposure and subsequently treated either by classical surgical debridement, by laser ablation, or left without treatment...
March 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28629611/sentinel-lymph-node-mapping-in-minimally-invasive-surgery-role-of-imaging-with-color-segmented-fluorescence-csf
#19
Maite I Lopez Labrousse, Michael Frumovitz, M Guadalupe Patrono, Pedro T Ramirez
OBJECTIVE: Sentinel lymph node mapping, alone or in combination with pelvic lymphadenectomy, is considered a standard approach in staging of patients with cervical or endometrial cancer [1-3]. The goal of this video is to demonstrate the use of indocyanine green (ICG) and color-segmented fluorescence when performing lymphatic mapping in patients with gynecologic malignancies. METHODS: Injection of ICG is performed in two cervical sites using 1mL (0.5mL superficial and deep, respectively) at the 3 and 9 o'clock position...
September 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28595496/reconstruction-of-input-functions-from-a-dynamic-pet-image-with-sequential-administration-of-15-o2-and-formula-see-text-for-noninvasive-and-ultra-rapid-measurement-of-cbf-oef-and-cmro2
#20
Nobuyuki Kudomi, Yukito Maeda, Hiroyuki Yamamoto, Yuka Yamamoto, Tetsuhiro Hatakeyama, Yoshihiro Nishiyama
CBF, OEF, and CMRO2 images can be quantitatively assessed using PET. Their image calculation requires arterial input functions, which require invasive procedure. The aim of the present study was to develop a non-invasive approach with image-derived input functions (IDIFs) using an image from an ultra-rapid O2 and C(15)O2 protocol. Our technique consists of using a formula to express the input using tissue curve with rate constants. For multiple tissue curves, the rate constants were estimated so as to minimize the differences of the inputs using the multiple tissue curves...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
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