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https://www.readbyqxmd.com/read/28531955/influence-of-sediment-chemistry-and-sediment-toxicity-on-macroinvertebrate-communities-across-99-wadable-streams-of-the-midwestern-usa
#1
Patrick W Moran, Lisa H Nowell, Nile E Kemble, Barbara J Mahler, Ian R Waite, Peter C Van Metre
Simultaneous assessment of sediment chemistry, sediment toxicity, and macroinvertebrate communities can provide multiple lines of evidence when investigating relations between sediment contaminants and ecological degradation. These three measures were evaluated at 99 wadable stream sites across 11 states in the Midwestern United States during the summer of 2013 to assess sediment pollution across a large agricultural landscape. This evaluation considers an extensive suite of sediment chemistry totaling 274 analytes (polycyclic aromatic hydrocarbons, organochlorine compounds, polychlorinated biphenyls, polybrominated diphenyl ethers, trace elements, and current-use pesticides) and a mixture assessment based on the ratios of detected compounds to available effects-based benchmarks...
May 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28504765/thermo-optic-characteristic-of-dna-thin-solid-film-and-its-application-as-a-biocompatible-optical-fiber-temperature-sensor
#2
Seongjin Hong, Woohyun Jung, Tavakol Nazari, Sanggwon Song, Taeoh Kim, Chai Quan, Kyunghwan Oh
We report unique thermo-optical characteristics of DNA-Cetyl tri-methyl ammonium (DNA-CTMA) thin solid film with a large negative thermo-optical coefficient of -3.4×10<sup>-4</sup>/°C in the temperature range from 20°C to 70°C without any observable thermal hysteresis. By combining this thermo-optic DNA film and fiber optic multimode interference (MMI) device, we experimentally demonstrated a highly sensitive compact temperature sensor with a large spectral shift of 0.15 nm/°C. The fiber optic MMI device was a concatenated structure with single-mode fiber (SMF)-coreless silica fiber (CSF)-single mode fiber (SMF) and the DNA-CTMA film was deposited on the CSF...
May 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28500303/photonic-crystal-and-quasi-crystals-providing-simultaneous-light-coupling-and-beam-splitting-within-a-low-refractive-index-slab-waveguide
#3
Jingxing Shi, Michael E Pollard, Cesar A Angeles, Ruiqi Chen, J C Gates, M D B Charlton
Coupling between free space components and slab waveguides is a common requirement for integrated optical devices, and is typically achieved by end-fire or grating coupling. Power splitting and distribution requires additional components. Usually grating couplers are used in combination with MMI/Y-splitters to do this task. In this paper, we present a photonic crystal device which performs both tasks simultaneously and is able to couple light at normal incidence and near normal incidence. Our approach is scalable to large channel counts with little impact on device footprint...
May 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28463704/recovery-of-orthographic-processing-after-stroke-a%C3%A2-longitudinal-fmri-study
#4
Jeremy Purcell, Rajani Sebastian, Richard Leigh, Samson Jarso, Cameron Davis, Joseph Posner, Amy Wright, Argye E Hillis
An intact orthographic processing system is critical for normal reading and spelling. Here we investigate the neural changes associated with impairment and subsequent recovery of the orthographic lexical processing system in an individual with an ischemic left posterior cerebral artery (PCA) stroke. This work describes a longitudinal case study of a patient, whose initials are MMY, with impairments in orthographic lexical processing for reading and spelling at stroke onset, and who recovered these skills within 1 year post stroke...
April 8, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28458607/novel-application-of-quantitative-single-photon-emission-computed-tomography-computed-tomography-to-predict-early-response-to-methimazole-in-graves-disease
#5
Hyun Joo Kim, Ji-In Bang, Ji-Young Kim, Jae Hoon Moon, Young So, Won Woo Lee
OBJECTIVE: Since Graves' disease (GD) is resistant to antithyroid drugs (ATDs), an accurate quantitative thyroid function measurement is required for the prediction of early responses to ATD. Quantitative parameters derived from the novel technology, single-photon emission computed tomography/computed tomography (SPECT/CT), were investigated for the prediction of achievement of euthyroidism after methimazole (MMI) treatment in GD. MATERIALS AND METHODS: A total of 36 GD patients (10 males, 26 females; mean age, 45...
May 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28421674/retraction-statement-dynamic-complex-formation-between-hd-gyp-ggdef-and-pilz-domain-proteins-regulates-motility-in-xanthomonas-campestris
#6
(no author information available yet)
The following article from Molecular Microbiology (2012) 86(3), 557-567, 'Dynamic complex formation between HD-GYP, GGDEF and PilZ domain proteins regulates motility in Xanthomonas campestris' by Robert P. Ryan, Yvonne McCarthy, Patrick A. Kiely, Rosemary O'Connor, Chuck S. Farah, Judith P. Armitage and J. Maxwell Dow published online in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor-in-Chief, John D Helmann, and John Wiley & Sons Ltd. Since publication of the above article, it has been brought to our attention that there are several image duplications across Figures 3, 5 and 6 including duplication with another article in PNAS: 'Cell-cell signal-dependent dynamic interactions between HD-GYP and GGDEF domain proteins mediate virulence in Xanthomonas campestris', by Robert P...
May 2017: Molecular Microbiology
https://www.readbyqxmd.com/read/28415896/multiple-mini-interviews-mmi-a-perspective-on-the-first-year-of-mmi-at-brighton-and-sussex-medical-school
#7
Simonne Tryb
Since it was developed at McMaster University School of Medicine in 2002, multiple medical interviews (MMI) have become a popular and accepted method of assessing candidates applying for medical training. Unlike a traditional panel interview it resembles the objective structured clinical examination (OSCE) with numerous 8-10 min stations assessing different topics or scenarios pertinent to medical training and healthcare. This was the first year of implementing MMI at Brighton and Sussex Medical School and my first year of interviewing...
April 18, 2017: Medical Teacher
https://www.readbyqxmd.com/read/28387513/heteroleptic-cycloplatinated-n-heterocyclic-carbene-complexes-a-new-approach-to-highly-efficient-blue-light-emitters
#8
Sara Fuertes, Andrés J Chueca, Lorenzo Arnal, Antonio Martín, Umberto Giovanella, Chiara Botta, Violeta Sicilia
New heteroleptic compounds of platinum(II)-containing cyclometalated N-heterocyclic carbenes, [PtCl(R-C^C*)(PPh3)] [R-CH^C*-κC* = 3-methyl-1-(naphthalen-2-yl)-1H-imidazol-2-ylidene (R-C = Naph; 1A), 1-[4-(ethoxycarbonyl)phenyl]-3-methyl-1H-imidazol-2-ylidene (R = CO2Et; 1B), and [Pt(R-C^C*)(py)(PPh3)]PF6 (py = pyridine; R-C = Naph, 2A; R = CO2Et, 2B], have been prepared and fully characterized. All of them were obtained as the trans-(C*,PPh3) isomer in high yields. The selectivity of their synthesis has been explained in terms of the degree of transphobia (T) of pairs of ligands in trans positions...
April 7, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28386276/cholesterol-synthesis-increased-in-the-mmi-induced-subclinical-hypothyroidism-mice-model
#9
Yongfeng Song, Xiujuan Zhang, Wenbin Chen, Ling Gao
Subclinical hypothyroidism (SCH) is defined as increased serum thyroid-stimulating hormone (TSH) concentrations and normal serum thyroid hormone (TH) levels as well as an increased serum cholesterol level, which is an important cause of secondary hypercholesterolemia and cardiovascular diseases. Some studies have demonstrated a direct effect of TSH on cholesterol metabolism via in vivo and in vitro experiments. However, because no suitable SCH model has been established until now, the changes in cholesterol synthesis that occur in SCH patients remain unknown...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28384391/trends-in-anecdotal-fox-sightings-in-tasmania-accounted-for-by-psychological-factors
#10
Clive A Marks, Malcolm Clark, David Obendorf, Graham P Hall, Inês Soares, Filipe Pereira
There has been little evaluation of anecdotal sightings as a means to confirm new incursions of invasive species. This paper explores the potential for equivocal information communicated by the media to account for patterns of anecdotal reports. In 2001 it was widely reported that red foxes (Vulpes vulpes) had been deliberately released in the island state of Tasmania (Australia), although this claim was later revealed to be baseless. Regardless, by 2013 a total of 3153 anecdotal fox sightings had been reported by members of the public and this implied the wide distribution of foxes...
April 6, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/28380944/realization-of-an-ultra-compact-polarization-beam-splitter-using-asymmetric-mmi-based-on-silicon-nitride-silicon-on-insulator-platform
#11
Xiao Sun, J Stewart Aitchison, Mo Mojahedi
We have experimentally demonstrated a compact polarization beam splitter (PBS) based on the silicon nitride/silicon-on-insulator platform using the recently proposed augmented-low-index-guiding (ALIG) waveguide structure. The two orthogonal polarizations are split in an asymmetric multimode interference (MMI) section, which was 1.6 μm wide and 4.8 μm long. The device works well over the entire C-band wavelength range and has a measured low insertion loss of less than 1 dB. The polarization extinction ratio at the Bar Port is approximately 17 dB and at the Cross Port is approximately 25 dB...
April 3, 2017: Optics Express
https://www.readbyqxmd.com/read/28380797/coreless-side-polished-fiber-a-novel-fiber-structure-for-multimode-interference-and-highly-sensitive-refractive-index-sensors
#12
Huazhuo Dong, Liheng Chen, Junjie Zhou, Jianhui Yu, Heyuan Guan, Wentao Qiu, Jiangli Dong, Huihui Lu, Jieyuan Tang, Wenguo Zhu, Zhigang Cai, Yi Xiao, Jun Zhang, Zhe Chen
A novel fiber structure, coreless side-polished fiber (CSPF), is proposed and investigated to implement multimode interference (MMI) and high sensitive refractive index (RI) sensors. For such CSPF, the part of the cladding and the core of a single-mode fiber are side-polished off so as to make the remained cladding a D-shaped multimode waveguide. The excitation and evolution of MMI in the CSPF are simulated numerically. The simulation results show that the high-order modes excited within the D-shaped multimode waveguide are mainly TE<sub>0,1</sub> (TM<sub>0,1</sub>)~TE<sub>0,6</sub> (TM<sub>0,6</sub>) modes...
March 6, 2017: Optics Express
https://www.readbyqxmd.com/read/28380749/passive-athermalization-of-multimode-interference-devices-for-wavelength-locking-applications
#13
Victor I Ruiz-Perez, Daniel A May-Arrioja, Jose R Guzman-Sepulveda
In this paper we demonstrate the passive, material-based athermalization of all-fiber architectures by cascading multimode interference (MMI) devices. In-line thermal compensation is achieved by including a liquid-core multimode section of variable length that allows ensuring temperature-independent operation while preserving the inherent filter-like spectral response of the MMI devices. The design of the temperature compensation unit is straightforward and its fabrication is simple. The applicability of our approach is experimentally verified by fabricating a wavelength-locked MMI laser with sensitivity of only -0...
March 6, 2017: Optics Express
https://www.readbyqxmd.com/read/28371777/facial-expression-recognition-based-on-deep-evolutional-spatial-temporal-networks
#14
Kaihao Zhang, Yongzhen Huang, Yong Du, Liang Wang
One key challenging issue of facial expression recognition is to capture the dynamic variation of facial physical structure from videos. In this paper, we propose a Part-based Hierarchical Bidirectional Recurrent Neural Network (PHRNN) to analyze the facial expression information of temporal sequences. Our PHRNN models facial morphological variations and dynamical evolution of expressions, which is effective to extract "temporal features" based on facial landmarks (geometry information) from consecutive frames...
March 30, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28368976/optical-coherence-tomography-angiography-to-distinguish-choroidal-neovascularization-from-macular-inflammatory-lesions-in-multifocal-choroiditis
#15
Polina Astroz, Alexandra Miere, Sarah Mrejen, Rim Sekfali, Eric H Souied, Camille Jung, Sylvia Nghiem-Buffet, Salomon Y Cohen
PURPOSE: To characterize the macular lesions in multifocal choroiditis using multimodal imaging (MMI) and to evaluate optical coherence tomography angiography (OCTA) in distinguishing neovascular from inflammatory lesions. METHODS: Retrospective review of medical records of consecutive patients diagnosed with multifocal choroiditis and macular involvement, between September 2014 and May 2016, were included. All patients underwent standard examination and MMI, including fundus color photography, fundus autofluorescence, fluorescein angiography, and spectral domain optical coherence tomography...
March 30, 2017: Retina
https://www.readbyqxmd.com/read/28344326/mutual-information-model-for-link-prediction-in-heterogeneous-complex-networks
#16
Hadi Shakibian, Nasrollah Moghadam Charkari
Recently, a number of meta-path based similarity indices like PathSim, HeteSim, and random walk have been proposed for link prediction in heterogeneous complex networks. However, these indices suffer from two major drawbacks. Firstly, they are primarily dependent on the connectivity degrees of node pairs without considering the further information provided by the given meta-path. Secondly, most of them are required to use a single and usually symmetric meta-path in advance. Hence, employing a set of different meta-paths is not straightforward...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28341216/effects-of-methimazole-on-drosophila-glucolipid-metabolism-in-vitro-and-in-vivo
#17
Qi Wei, Bo Hu, Yuan Xue, David Kibe Mburu, Xian Tao, Jianya Su
Methimazole (MMI) is an antithyroid agent widely used in the treatment of hyperthyroidism, and metabolized by cytochrome P450 enzymes and flavin-containing monooxygenases in mammals. However, drug overdose and the inadequate detoxification of the metabolite(s) are responsible for hepatocellular damage and organ dysfunction. Depending on the desired properties, Drosophila melanogaster has recently emerged as an ideal model organism for the study of human diseases. Here we investigated the changes in metabolic profiles and mRNA expressions related to glucolipid metabolism in response to treatment with MMI in Drosophila...
March 21, 2017: Comparative Biochemistry and Physiology. Toxicology & Pharmacology: CBP
https://www.readbyqxmd.com/read/28324105/thyroid-hormone-dependent-epigenetic-regulation-of-melanocortin-4-receptor-levels-in-female-offspring-of-obese-rats
#18
Tzlil Tabachnik, Tatiana Kisliouk, Asaf Marco, Noam Meiri, Aron Weller
Maternal obesity is a risk factor for offspring obesity. The melanocortin 4 receptor (Mc4r) is one of the mediators of food intake and energy balance. The present study examined the epigenetic mechanisms underlying altered Mc4r levels in the hypothalamic paraventricular nucleus in the offspring of high-fat diet (HFD)-induced obese dams and sought to elucidate the role of thyroid hormones in epigenetic regulation and tagging of their nucleosome at the Mc4r promoter. Female Wistar rats were fed an HFD or standard chow from weaning through gestation and lactation...
April 1, 2017: Endocrinology
https://www.readbyqxmd.com/read/28302124/reliability-and-acceptability-of-six-station-multiple-mini-interviews-past-behavioural-versus-situational-questions-in-postgraduate-medical-admission
#19
Toru Yamada, Juichi Sato, Hiroshi Yoshimura, Tomoya Okubo, Eiji Hiraoka, Takashi Shiga, Tadao Kubota, Shigeki Fujitani, Junji Machi, Nobutaro Ban
BACKGROUND: The multiple mini-interview (MMI) is increasingly used for postgraduate medical admissions and in undergraduate settings. MMIs use mostly Situational Questions (SQs) rather than Past-Behavioural Questions (PBQs). A previous study of MMIs in this setting, where PBQs and SQs were asked in the same order, reported that the reliability of PBQs was non-inferior to SQs and that SQs were more acceptable to candidates. The order in which the questions are asked may affect reliability and acceptability of an MMI...
March 16, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28279752/novel-spiroimidazopyridine-derivative-sak3-improves-methimazole-induced-cognitive-deficits-in-mice
#20
Husain Noreen, Yasushi Yabuki, Kohji Fukunaga
Methimazole (MMI) is a first-line therapy used to manage hyperthyroidism and Graves' disease. Despite its therapeutic benefit, chronic MMI administration can lead to hypothyroidism and perturb brain homeostasis in patients, resulting in neuropsychiatric disorders such as depression and cognitive dysfunction. We recently developed the spiroimidazopyridine derivative SAK3 as cognitive enhancer; however, mechanisms underlying its activity remained unclear. Here, we show that SAK3 potentially improves cognitive impairment seen following MMI-induced hypothyroidism...
March 6, 2017: Neurochemistry International
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