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https://www.readbyqxmd.com/read/29143783/metformin-potentiates-the-benefits-of-dietary-restraint-a-metabolomic-study
#1
Marta Riera-Borrull, Anabel García-Heredia, Salvador Fernández-Arroyo, Anna Hernández-Aguilera, Noemí Cabré, Elisabet Cuyàs, Fedra Luciano-Mateo, Jordi Camps, Javier A Menendez, Jorge Joven
Prevention of the metabolic consequences of a chronic energy-dense/high-fat diet (HFD) represents a public health priority. Metformin is a strong candidate to be incorporated in alternative therapeutic approaches. We used a targeted metabolomic approach to assess changes related to the multi-faceted metabolic disturbances provoked by HFD. We evaluated the protective effects of metformin and explored how pro-inflammatory and metabolic changes respond when mice rendered obese, glucose-intolerant and hyperlipidemic were switched to diet reversal with or without metformin...
October 28, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29141975/dietary-strategies-to-reduce-environmental-impact-a-critical-review-of-the-evidence-base
#2
REVIEW
Bradley G Ridoutt, Gilly A Hendrie, Manny Noakes
The food system is a major source of environmental impact, and dietary change has been recommended as an important and necessary strategy to reduce this impact. However, assessing the environmental performance of diets is complex due to the many types of foods eaten and the diversity of agricultural production systems and local environmental settings. To assess the state of science and identify knowledge gaps, an integrative review of the broad topic of environment and diet was undertaken, with particular focus on the completeness of coverage of environmental concerns and the metrics used...
November 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/29139074/excessive-use-of-nitrogenous-fertilizers-an-unawareness-causing-serious-threats-to-environment-and-human-health
#3
Moddassir Ahmed, Muhammad Rauf, Zahid Mukhtar, Nasir Ahmad Saeed
Farmers occasionally need to add nitrogen fertilizer to their farms and gardens to make available just the precise nutrients for their plants' growth. The applications of inorganic nitrogen fertilizers to various crops have been continuously increasing since last many decades globally. Although nitrogen fertilizer contributes substantially to yield enhancement, but excessive use of this manure has posed serious threats to environment and human health. Rate of nitrogen fertilizers application has a close relationship with nitrate accumulation in surrounding environment, groundwater, as well as leafy and root vegetables...
November 14, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29134858/ancel-benjamin-keys-1904-2004-his-early-works-and-the-legacy-of-the-modern-mediterranean-diet
#4
Basil H Aboul-Enein, William C Puddy, Joshua Bernstein
Culturally congruent dietary patterns have evolved with geographic and societal traditions and can be traced as far back as pre-Hellenistic Greece. Today, the modern Mediterranean diet (MDiet) is recognized internationally as an anti-obesogenic cardioprotective dietary model consisting of plant-based foods native to the Mediterranean basin, fish, olive oil, and an active lifestyle. With the assumption that obesity and heart disease rates adversely affected life expectancy, the MDiet was identified by Dr Ancel Keys as a primary characteristic among people-groups largely immune to these trends...
January 1, 2017: Journal of Medical Biography
https://www.readbyqxmd.com/read/29130723/-telomeres-and-diet-quality
#5
Amelia Marti, Raquel Echeverría, Lydia Morell-Azanza, Ana Ojeda-Rodríguez
BACKGROUND: Few studies have evaluated the relationship between diet quality and telomere integrity in humans. Telomeres are regions of non-coding DNA localized at the end of each chromosome whose length, in addition to indicating life expectancy, indicates an overall health status. The objective of this systematic review is to compile the existing evidence on the relationship between telomere length and diet quality to further explore the impact that some nutrients, foods and dietary patterns may have on telomere homeostasis and therefore, in precision nutrition strategies...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29130289/development-and-pilot-testing-of-a-parent-reported-health-related-quality-of-life-measure-for-children-on-the-ketogenic-diet-the-ketoqol
#6
Katie Barwick, Tamara Parker, Nicole Murphy, Alwyn Todd, Michael Leveritt, Shelley A Wilkinson
AIM: The aim of the present study was to develop a parent-reported tool that will measure health-related quality of life (HRQoL) in children following ketogenic diet (KD) therapies for refractory epilepsy once it has been pilot tested and analysed. METHODS: Parents of children following KD therapies for epilepsy were recruited through a public hospital in Queensland, Australia, in 2012 and 2014. Qualitative semistructured interviews were conducted in 2012 with 13 parents who described changes seen in their child's HRQoL while on the KD...
November 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/29129429/serum-concentrations-of-organochlorine-compounds-and-predictors-of%C3%A2-exposure-in-children-living-in-agricultural-communities-from-south-eastern-spain
#7
B González-Alzaga, M Lacasaña, A F Hernández, J P Arrebola, I López-Flores, F Artacho-Cordón, J P Bonde, N Olea, C Aguilar-Garduño
BACKGROUND: Information on exposure levels to organochlorine compounds (OCs) in child population is limited, despite their greater vulnerability to the adverse health effects of these chemicals. OBJECTIVE: To determine serum concentrations of 10 OCs (including organochlorine pesticides and polychlorinated biphenyls -PCBs-) in children living in agricultural communities from Almería (South-Eastern Spain), and to identify the main predictors of exposure related to socio-economic characteristics, diet and lifestyle...
November 9, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29128408/adding-folic-acid-to-corn-masa-flour-partnering-to-improve-pregnancy-outcomes-and-reduce-health-disparities
#8
REVIEW
Alina L Flores, Amy M Cordero, Michael Dunn, Joseph E Sniezek, Miguel A Arce, Krista S Crider, Sarah Tinker, Cynthia Pellegrini, Rita Carreón, Jose Estrada, Sara Struwe, Coleen Boyle
Although strides have been made in preventing neural tube defects (NTDs), Hispanic women remain more likely to have a baby born with an NTD and less likely to know the benefits of, or consume, folic acid than women of other race/ethnic groups. In 1998, the U.S. Food and Drug Administration (FDA) mandated that all enriched cereal grain products be fortified with folic acid; however, corn masa flour (CMF), used to make many corn products that are a diet staple of many Hispanic groups, was not included under this regulation...
November 8, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29126995/fvd-the-fish-associated-virus-database
#9
Yaxin Chen, Mijuan Shi, Yingyin Cheng, Wanting Zhang, Qin Tang, Xiao-Qin Xia
With the expanding of marine and freshwater aquaculture, the outbreaks of aquatic animal diseases have increasingly become the major threats to the healthy development of aquaculture industries. Notably, viral infections lead to massive fish deaths and result in great economic loss every year across the world. Hence, it is meaningful to clarify the biodiversity, geographical distribution and host specificity of fish-associated viruses. In this study, viral sequences detected in fish samples were manually collected from public resources, along with the related metadata, such as sampling time, location, specimen type and fish species...
November 7, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29125537/associations-of-fasting-blood-glucose-with-influencing-factors-in-northeast-china-a-quantile-regression-analysis
#10
Xin Guo, Li Shen, Jing Dou, Yaogai Lv, Anning Zhang, Fanchao Shi, Zhiqiang Xue, Yaqin Yu, Lina Jin, Yan Yao
Background: Diabetes mellitus (DM) has become a major public health problem in China. Although a number of researchers have investigated DM risk factors, little is known about the associations between values of fasting blood glucose (FBG) and influencing factors. This study aims to explore these associations by the quantile regression (QR) model. Methods: A cross-sectional survey based on a sample of 23,050 adults aged 18 to 79 years was conducted in Jilin in 2012, and some subjects were excluded due to missing values with respect to necessary variables or having glycemic control, in accordance with the purposes of this study...
November 10, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29125179/the-impact-of-sociodemography-diet-and-body-size-on-serum-retinol-in-women-16-35-years-of-age-sanhanes-1
#11
Whadi-Ah Parker, Zandile J Mchiza, Ronel Sewpaul, Nophiwe Job, Lumbwe Chola, Moses Sithole, Demetre Labadarios
To determine the current vitamin A status of a nationally representative sample of women aged 16-35 years, compare it with previous national data, and determine the impact of sociodemography, diet, and body size on vitamin A status, we performed secondary analysis of data on South African women who participated in the first South African National Health and Nutrition Examination Survey (SANHANES-1). Vitamin A status was assessed by serum retinol, and the findings are reported as means and prevalences with corresponding 95% confidence intervals...
November 10, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29118995/added-fructose-as-a-principal-driver-of-non-alcoholic-fatty-liver-disease-a-public-health-crisis
#12
EDITORIAL
James J DiNicolantonio, Ashwin M Subramonian, James H O'Keefe
Fatty liver disease affects up to one out of every two adults in the western world. Data from animal and human studies implicate added sugars (eg, sucrose and high-fructose corn syrup) in the development of fatty liver disease and its consequences. Added fructose in particular, as a component of added sugars, may pose the greatest risk for fatty liver disease. Considering that there is no requirement for added sugars in the diet, dietary guidelines should recommend reducing the intake of added sugars to just 5% of total calories in order to decrease the prevalence of fatty liver disease and its related consequences...
2017: Open Heart
https://www.readbyqxmd.com/read/29117929/a-fully-automated-web-based-program-improves-lifestyle-habits-and-hba1c-in-patients-with-type-2-diabetes-and-abdominal-obesity-randomized-trial-of-patient-e-coaching-nutritional-support-the-anode-study
#13
Boris Hansel, Philippe Giral, Laetitia Gambotti, Alexandre Lafourcade, Gilbert Peres, Claude Filipecki, Diana Kadouch, Agnes Hartemann, Jean-Michel Oppert, Eric Bruckert, Michel Marre, Arnaud Bruneel, Emilie Duchene, Ronan Roussel
BACKGROUND: The prevalence of abdominal obesity and type 2 diabetes mellitus (T2DM) is a public health challenge. New solutions need to be developed to help patients implement lifestyle changes. OBJECTIVE: The objective of the study was to evaluate a fully automated Web-based intervention designed to help users improve their dietary habits and increase their physical activity. METHODS: The Accompagnement Nutritionnel de l'Obésité et du Diabète par E-coaching (ANODE) study was a 16-week, 1:1 parallel-arm, open-label randomized clinical trial...
November 8, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29117146/transferability-of-the-mediterranean-diet-to-non-mediterranean-countries-what-is-and-what-is-not-the-mediterranean-diet
#14
Miguel Ángel Martínez-González, Maria Soledad Hershey, Itziar Zazpe, Antonia Trichopoulou
Substantial evidence has verified the Mediterranean diet's (MedDiet) nutritional adequacy, long-term sustainability, and effectiveness for preventing hard clinical events from cardiovascular disease (CVD), as well as increasing longevity. This article includes a cumulative meta-analysis of prospective studies supporting a strong inverse association between closer adherence to the MedDiet and the incidence of hard clinical events of CVD. The MedDiet has become an increasingly popular topic of interest when focusing on overall food patterns rather than single nutrient intake, not only in Mediterranean countries, but also globally...
November 8, 2017: Nutrients
https://www.readbyqxmd.com/read/29115995/developing-a-systems-based-framework-of-the-factors-influencing-dietary-and-physical-activity-behaviours-in-ethnic-minority-populations-living-in-europe-a-dedipac-study
#15
Michelle Holdsworth, Mary Nicolaou, Lars Jørun Langøien, Hibbah Araba Osei-Kwasi, Sebastien F M Chastin, F Marijn Stok, Laura Capranica, Nanna Lien, Laura Terragni, Pablo Monsivais, Mario Mazzocchi, Lea Maes, Gun Roos, Caroline Mejean, Katie Powell, Karien Stronks
BACKGROUND: Some ethnic minority populations have a higher risk of non-communicable diseases than the majority European population. Diet and physical activity behaviours contribute to this risk, shaped by a system of inter-related factors. This study mapped a systems-based framework of the factors influencing dietary and physical activity behaviours in ethnic minority populations living in Europe, to inform research prioritisation and intervention development. METHODS: A concept mapping approach guided by systems thinking was used: i...
November 7, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/29114246/variation-of-carbohydrate-active-enzyme-patterns-in-the-gut-microbiota-of-italian-healthy-subjects-and-type-2-diabetes-patients
#16
Matteo Soverini, Silvia Turroni, Elena Biagi, Sara Quercia, Patrizia Brigidi, Marco Candela, Simone Rampelli
The human gut microbiota (GM) has been associated, to date, with various complex functions, essentials for the host health. Among these, it is certainly worth noting the degradation of the so-called microbiota-accessible carbohydrates (MACs), which the GM breaks down through specific enzymes, referred to as carbohydrate-active enzymes (CAZymes). This degradation constitutes the first step in the production of short-chain fatty acids (SCFAs), key microbial small molecules having multiple health-promoting effects for the host organism...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29113510/interrelationship-of-canonical-and-non-canonical-wnt-signalling-pathways-in-chronic-metabolic-diseases
#17
Ian Ackers, Ramiro Malgor
Chronic diseases account for approximately 45% of all deaths in developed countries and are particularly prevalent in countries with the most sophisticated and robust public health systems. Chronic metabolic diseases, specifically lifestyle-related diseases pertaining to diet and exercise, continue to be difficult to treat clinically. The most prevalent of these chronic metabolic diseases include obesity, diabetes, non-alcoholic fatty liver disease, chronic kidney disease and cardiovascular disease and will be the focus of this review...
November 1, 2017: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/29111882/depletion-of-tylosin-residues-in-feathers-muscle-and-liver-from-broiler-chickens-after-completion-of-antimicrobial-therapy
#18
Javiera Cornejo, Ekaterina Pokrant, Carolina Carvallo, Aldo Maddaleno, Betty San Martín
Tylosin is one of the most commonly used antimicrobial drugs from the macrolide family and in broiler chickens it is used specially for the treatment of infectious pathologies. The poultry industry produces several by-products, among which feathers account for up to 7 percent of a chicken's live weight, thus they amount to a substantial mass across the whole industry. Feathers have been repurposed as an animal feed ingredient by making them feather meal. Therefore, the presence of high concentrations of residues from antimicrobial drugs in feathers might pose a risk to global public health, due to re-entry of these residues into the food chain...
November 7, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/29109723/inhibition-of-pro-inflammatory-and-anti-apoptotic-biomarkers-during-experimental-oral-cancer-chemoprevention-by-dietary-black-raspberries
#19
Steve Oghumu, Bruce C Casto, Jennifer Ahn-Jarvis, Logan C Weghorst, Jim Maloney, Paul Geuy, Kyle Z Horvath, Claire E Bollinger, Blake M Warner, Kurt F Summersgill, Christopher M Weghorst, Thomas J Knobloch
Oral cancer continues to be a significant public health problem worldwide. Recently conducted clinical trials demonstrate the ability of black raspberries (BRBs) to modulate biomarkers of molecular efficacy that supports a chemopreventive strategy against oral cancer. However, it is essential that a preclinical animal model of black raspberry (BRB) chemoprevention which recapitulates human oral carcinogenesis be developed, so that we can validate biomarkers and evaluate potential mechanisms of action. We therefore established the ability of BRBs to inhibit oral lesion formation in a carcinogen-induced rat oral cancer model and examined potential mechanisms...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29109090/impact-of-mediterranean-diet-on-cancer-focused-literature-review
#20
REVIEW
Yoram Barak, Dana Fridman
BACKGROUND: Cancer is a major public health problem worldwide, and the number of incident cases increases every year expected to reach 17.1 million a year by 2020. There is evidence that people who adhere to the Mediterranean Diet (MediD) have lower incidence of cancer. However, cancers' location and culture studies seem to affect the MediD impact. We aimed to review these discrepant findings. MATERIALS AND METHODS: A critical review from a focused literature search was conducted...
November 2017: Cancer Genomics & Proteomics
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