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https://www.readbyqxmd.com/read/29355704/endurance-exercise-prevents-high-fat-diet-induced-locomotor-impairment-cardiac-dysfunction-lifespan-shortening-and-dsir2-expression-decline-in-aging-drosophila
#1
Deng-Tai Wen, Lan Zheng, Fan Yang, Han-Zhe Li, Jing Chen
High-Fat-Diet (HFD)-induced obesity is a major contributor to premature senescence in both Drosophila and humans, which includes locomotor impairment, cardiac dysfunction, and decrease in lifespan. While, few studies have shown that HFD could affect the expression dSir2 genes since the dSir2 genes are closely related to aging. As we know, endurance exercise can efficiently prevent obesity and delay age-related functional decline in Drosophila and humans. However, few directed reports showing that exercise can resist HFD-induced locomotor impairment, cardiac dysfunction and decrease in lifespan...
January 16, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29354930/-skin-needle-embedding-for-obese-impaired-glucose-tolerance
#2
Jinghua Liang, Zhendi Feng, Shengkui Feng, Shude Bao, Kejia Wang
OBJECTIVE: To explore the effect difference between the skin needle embedding therapy and western medication for obese impaired glucose tolerance (IGT). METHODS: A total of 300 cases of obese IGT were assigned into an embedding group and a western medication group by random number table, 150 cases in each one. Standardized diagnosis and treatment programs were applied to reduce blood pressure, lipid, weight, and exercise and scientific diet management were used...
January 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29352196/hyper-hippocampal-glycogen-induced-by-glycogen-loading-with-exhaustive-exercise
#3
Mariko Soya, Takashi Matsui, Takeru Shima, Subrina Jesmin, Naomi Omi, Hideaki Soya
Glycogen loading (GL), a well-known type of sports conditioning, in combination with exercise and a high carbohydrate diet (HCD) for 1 week enhances individual endurance capacity through muscle glycogen supercompensation. This exercise-diet combination is necessary for successful GL. Glycogen in the brain contributes to hippocampus-related memory functions and endurance capacity. Although the effect of HCD on the brain remains unknown, brain supercompensation occurs following exhaustive exercise (EE), a component of GL...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29349905/would-you-like-to-add-a-weight-after-this-blood-pressure-doctor-discovery-of-potentially-actionable-associations-between-the-provision-of-multiple-screens-in-primary-care
#4
Sumeet Kalia, Michelle Greiver, Xu Zhao, Christopher Meaney, Rahim Moineddin, Babak Aliarzadeh, Eva Grunfeld, Frank Sullivan
RATIONALE, AIMS, AND OBJECTIVE: Guidelines recommend screening for risk factors associated with chronic diseases but current electronic prompts have limited effects. Our objective was to discover and rank associations between the presence of screens to plan more efficient prompts in primary care. METHODS: Risk factors with the greatest impact on chronic diseases are associated with blood pressure, body mass index, waist circumference, glycaemic and lipid levels, smoking, alcohol use, diet, and exercise...
January 19, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29349727/lifestyles-of-patients-with-functional-psychosis-compared-to-those-of-a-sample-of-the-regional-general-population-findings-from-a-study-in-a-community-mental-health-service-of-the-veneto-region-italy
#5
Loretta Berti, Elena Bonfioli, Linda Chioffi, Susanna Morgante, Maria Angela Mazzi, Lorenzo Burti
Unhealthy lifestyles contribute, with other risk factors, to the high prevalence of mortality and physical comorbidity among mental patients compared to the general population. We collected data on the lifestyles of 193 subjects with psychosis in contact with a Community Mental Health Service in north-eastern Italy and compared them with a representative sample (total: 3219 subjects) of the general population of the same region. Diet, exercise, smoking and alcohol consumption were worse in mental patients. A higher percentage of patients was overweight or obese...
January 18, 2018: Community Mental Health Journal
https://www.readbyqxmd.com/read/29348994/the-association-of-mediterranean-diet-and-exercise-modifications-with-anthropometric-parameters-in-a-psychiatric-community-population-a-pilot-study
#6
Rosaria Di Lorenzo, Jessica Pedretti, Letizia Grossi, Benedetta Cuoghi, Cinzia Varni, Giulia Landi, Ludovica Spattini, Chiara Visentini, Paola Ferri, Francesca Carubbi
Weight gain and related metabolic syndrome (MS) are major current issues in public health. MS consists of abdominal fat, atherogenic dyslipidemia, hypertension, hyperglycemia, insulin resistance, pro-inflammatory and pro-thrombotic state, and accounts for both cardiovascular diseases and type II diabetes mellitus risk factors. Patients affected by psychiatric illness present a prevalence of 35-40% of MS. Many studies have shown that Mediterranean diet is associated with the reduction of mortality due to cardiovascular and malignant diseases, potentially preventing both obesity and type II diabetes mellitus...
March 2018: Preventive Medicine Reports
https://www.readbyqxmd.com/read/29346467/modification-of-the-associations-between-duration-of-oral-contraceptive-use-and-ovarian-endometrial-breast-and-colorectal-cancers
#7
Kara A Michels, Ruth M Pfeiffer, Louise A Brinton, Britton Trabert
Importance: Although oral contraceptive (OC) use is common, the influence of OC use on carcinogenesis is not fully understood. A recent Agency for Healthcare Research and Quality report identified a need to understand the consistency of OC use and cancer associations across subpopulations, including smokers and obese women. Objective: To determine whether associations between duration of OC use and risk of specific cancers were modified by lifestyle characteristics...
January 18, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29345841/effects-of-high-impact-exercise-on-the-physical-properties-of-bones-of-ovariectomized-rats-fed-to-a-high-protein-diet
#8
Roberta Carminati Shimano, Gabriela Rezende Yanagihara, Ana Paula Macedo, Jessica Suzuki Yamanaka, Antônio Carlos Shimano, João Manuel R S Tavares, João Paulo Mardegan Issa
The aim of this study was to evaluate the effects of high-impact physical exercise as a prophylactic and therapeutic means in osteopenic bones of rats submitted to ovariectomy and protein diet intake. A total of 64 Wistar rats were divided into eight groups (n=8 each), being: OVX, ovx, standard diet and sedentary; OVXE, ovx, standard diet and jump; OVXP, ovx, high-protein diet and sedentary; and OVXEP, ovx, high-protein diet and jump; SH, sham, standard diet and sedentary; SHE, sham, standard diet and jump; SHP, sham, high-protein diet and sedentary; and SHEP, sham, high-protein-diet and jump...
January 18, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29345123/the-effects-of-lifestyle-changes-on-serum-lipid-levels-in-children-in-a-real-life-setting
#9
Angeline D Opina, Constance Cephus, Yunfei Wang, Samuel Younan, Douglas Moodie
OBJECTIVE: Studies have shown improvement in lipid levels after institution of lifestyle changes in children enrolled in closely monitored programs. There programs are difficult to mimic in real world clinics. We aim to determine if diet and exercise result in improvement in lipid levels in patients seen in a designated lipid clinic in a real life setting. DESIGN: Retrospective review of patients followed for dyslipidemia at the Texas Children's Hospital Lipid Clinic from May 1, 2012 to May 1, 2015...
January 18, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/29344750/physical-activity-and-consumption-patterns-of-reproductive-aged-women-by-bmi-category
#10
Jennifer K Bello, Debra B Stulberg, Ying Zhou, Chi Wang
Objectives Obesity before and during pregnancy is associated with adverse effects for mother and child, but little is known about physical activity and consumption patterns among reproductive-aged women. The goal of this study is to identify behaviors of nonpregnant reproductive-aged women associated with normal weight, overweight, and obesity. Methods Data from the nationally representative National Eating Trends survey (2003-2011) were analyzed, comparing number of days of exercise in a 1-week period and consumption of fruits/vegetables, sugar sweetened beverages (SSB), and concentrated sweets by BMI...
January 17, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29344657/effects-of-hereditary-moderate-high-fat-diet-on-metabolic-performance-and-physical-endurance-capacity-in-c57bl-6-offspring
#11
Fang Liu, Guirong Zhang, Xue Sheng, Shang Liu, Meng Cui, Heyun Guo, Jianbin Xue, Lingyun Zhang
Obesity in pregnant women presents a risk to fetal health, leading to numerous metabolic syndromes and chronic inflammation risks. Previously, physical exercise was considered to be one of the primary treatments for obesity. However, the effect of fat consumption throughout the life cycle on physical endurance capacity remains unknown. A total of two groups of female mice (age, 6 weeks; C57BL/6J) were fed with a normal chow diet and a moderate high fat diet (MHFD), during pregnancy and lactation (8 weeks), with the offspring receiving the same diet as the mother...
January 16, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29344401/protocol-for-moving-on-a-randomized-controlled-trial-to-increase-outcome-expectations-and-exercise-among-breast-cancer-survivors
#12
Rachel Hirschey, Gretchen Kimmick, Marilyn Hockenberry, Ryan Shaw, Wei Pan, Isaac Lipkus
Aim: The aim of this study was to test the feasibility and fidelity of an intervention, Moving On, aimed to increase outcome expectations OEs (i.e. what one expects to obtain or avoid as a result of a behaviour) and exercise among breast cancer survivors. Design: Randomized controlled trial. Methods: Intervention arm participants will be given a theory-guided booklet that was co-created by the research team and three physically active breast cancer survivors who exercise to manage late and long-term treatment effects...
January 2018: Nursing Open
https://www.readbyqxmd.com/read/29344023/eicosapentaenoic-acid-as-a-potential-therapeutic-approach-to-reduce-cardiovascular-risk-in-patients-with-end-stage-renal-disease-on-hemodialysis-a-review
#13
REVIEW
Kenneth M Borow, R Preston Mason, Krishnaswami Vijayaraghavan
Background: Patients with end-stage renal disease on hemodialysis have excess cardiovascular disease (CVD) burden with substantially increased CV event rates compared with the general population. Summary: Traditional interventions that, according to standard clinical guidelines, reduce CV risk such as antihypertensive therapy, diet, exercise, and statins are not similarly effective in the hemodialysis population. This raises the question of whether additional risk factors, such as enhanced inflammation and oxidative stress, may drive the increased CVD burden in hemodialysis patients...
December 2017: Cardiorenal Medicine
https://www.readbyqxmd.com/read/29343168/assessment-of-goals-and-priorities-in-patients-with-a-chronic-condition-a-secondary-quantitative-analysis-of-determinants-across-11-countries
#14
Neeltje P C A Vermunt, Gert P Westert, Marcel G M Olde Rikkert, Marjan J Faber
OBJECTIVE: To assess the impact of patient characteristics, patient-professional engagement, communication and context on the probability that healthcare professionals will discuss goals or priorities with older patients. DESIGN: Secondary analysis of cross-sectional data from the 2014 Commonwealth Fund International Health Policy Survey of Older Adults. SETTING: 11 western countries. SUBJECTS: Community-dwelling adults, aged 55 or older...
January 18, 2018: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/29340618/mitochondrial-toxicity
#15
Joel N Meyer, Jessica H Hartman, Danielle F Mello
Recent decades have seen a rapid increase in reported toxic effects of drugs and pollutants on mitochondria. Researchers have also documented many genetic differences leading to mitochondrial diseases, currently reported to affect ∼1 person in 4,300, creating a large number of potential gene-environment interactions in mitochondrial toxicity. We briefly review this history, and then highlight cutting-edge areas of mitochondrial research including the role of mitochondrial reactive oxygen species in signaling; increased understanding of fundamental biological processes involved in mitochondrial homeostasis (DNA maintenance and mutagenesis, mitochondrial stress response pathways, fusion and fission, autophagy and biogenesis, and exocytosis); systemic effects resulting from mitochondrial stresses in specific cell types; mitochondrial involvement in immune function; the growing evidence of long-term effects of mitochondrial toxicity; mitochondrial-epigenetic cross-talk; and newer approaches to test chemicals for mitochondrial toxicity...
January 11, 2018: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/29338438/challenges-in-adult-vaccination
#16
Eduardo de Gomensoro, Giuseppe Del Giudice, T Mark Doherty
Life-long primary prevention interventions beginning and continuing throughout an individual's lifetime are increasingly seen as key to meeting the global healthcare challenges that accompany demographic changes - a concept referred to as "Healthy aging". In this perspective, vaccination is seen as part of a triad, together with healthy diet and exercise. Current adult vaccine coverage is lower than target vaccination rates in most developed countries, and so vaccine preventable diseases continue to present a substantial burden on health and healthcare resources, especially in older individuals...
January 16, 2018: Annals of Medicine
https://www.readbyqxmd.com/read/29336622/nutritional-supplement-and-functional-food-use-among-medical-students-in-india
#17
Nitin Joseph, Abhinav Kumar, Harjas Singh, Mohammed Shaheen, Kriti Das, Apurva Shrivastava
This study was conducted to assess the pattern of use of nutritional supplements (NSs) and functional foods (FFs), reasons for their use, factors influencing their use, and perception toward their use among medical students. Data were collected from 400 randomly chosen participants using a self-administered semistructured questionnaire. The most common source of information on these substances was from medical professionals (n = 140 [35%]). Multivitamins were consumed by 48 (45.3%) participants. Most common reasons stated for the use of supplements were for good health (n = 39 [36...
January 16, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29335239/comparing-diet-and-exercise-monitoring-using-smartphone-app-and-paper-diary-a-two-phase-intervention-study
#18
Florence Jimoh, Elizabeth K Lund, Linda J Harvey, Catherine Frost, W James Lay, Mark A Roe, Rachel Berry, Paul M Finglas
BACKGROUND: There is increasing recognition that personalized approaches may be more effective in helping people establish healthier eating patterns and exercise more, and that this approach may be particularly effective in adolescents. OBJECTIVE: The objective of this study was to investigate the use of a smartphone app (FoodWiz2) in supporting healthy lifestyle choices in adolescence. METHODS: Participants (N=34: 11 male, 23 female) aged 16-19 years in full- or part-time education were recruited from sixth form colleges, schools, and other further education establishments in Norfolk and Suffolk, United Kingdom, between February and May 2015...
January 15, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29333789/physical-training-in-a-medical-fitness-room-for-patients-with-chronic-diseases-functional-and-metabolic-outcomes
#19
Oshrat E Tayer-Shifman, Yigal Bar-On, David Pereg, Alon Y Hershko
BACKGROUND: Physical inactivity is a pivotal factor in the development and progression of various chronic diseases. However, most fitness facilities exclude unhealthy individuals. Therefore, an exercise program that admits such patients is imperative. OBJECTIVES: To evaluate the effectiveness of a fitness facility that admits adult subjects with multiple chronic diseases. METHODS: We conducted a retrospective screening of patient records from the Medical Fitness Facility at Meir Medical Center, Israel...
January 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29332264/the-role-of-affect-and-coping-in-diabetes-self-management-in-rural-adults-with-uncontrolled-diabetes-and-depressive-symptoms
#20
Shannon R Miles, Tasneem Khambaty, Nancy J Petersen, Aanand D Naik, Jeffrey A Cully
Many patients with diabetes have poorly controlled blood sugar levels and remain at risk for serious diabetes complications, despite access to effective diabetes treatments and services. Using the transactional model of stress and coping framework, the study investigated the contributions of affect (Positive and Negative Affect Schedule) and coping (maladaptive and adaptive coping from the Brief Cope) on diabetes self-management behaviors, namely diet and exercise. One hundred seventy-eight rural adults with uncontrolled diabetes and moderate depressive symptoms completed the measures...
January 13, 2018: Journal of Clinical Psychology in Medical Settings
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