Sweta Bhagavatula, Ryan Cabeen, Neil G Harris, Olli Gröhn, David K Wright, Rachael Garner, Alexis Bennett, Celina Alba, Aubrey Martinez, Xavier Ekolle Ndode-Ekane, Pedro Andrade, Tomi Paananen, Robert Ciszek, Riikka Immonen, Eppu Manninen, Noora Puhakka, Jussi Tohka, Mette Heiskanen, Idrish Ali, Sandy R Shultz, Pablo M Casillas-Espinosa, Glenn R Yamakawa, Nigel C Jones, Matthew R Hudson, Juliana C Silva, Emma L Braine, Rhys D Brady, Cesar E Santana-Gomez, Gregory D Smith, Richard Staba, Terence J O'Brien, Asla Pitkänen, Dominique Duncan
Preclinical MRI studies have been utilized for the discovery of biomarkers that predict post-traumatic epilepsy (PTE). However, these single site studies often lack statistical power due to limited and homogeneous datasets. Therefore, multisite studies, such as the Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx), are developed to create large, heterogeneous datasets that can lead to more statistically significant results. EpiBioS4Rx collects preclinical data internationally across sites, including the United States, Finland, and Australia...
September 2023: Epilepsy Research