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https://www.readbyqxmd.com/read/27754076/os-18-08-optimal-blood-pressure-goal-for-the-elderly-chinese-the-findings-from-the-northern-shanghai-study
#1
Jiadela Teliewubai, Yu-Yan Lv, Shi-Kai Yu, Bin Bai, Chen Chi, Kai Wang, Yi-Wu Zhou, Jing Xiong, Yi Zhang, Ya-Wei Xu
OBJECTIVE: The Eighth Joint National Committee Panel recommended novel blood pressure (BP) goals for individuals with hypertension, which is still under debate. We therefore assessed patients' target organ damages in controlled hypertensives defined by the Seventh or Eighth Joint National Committee thresholds (JNC7 and JNC8) in a community-based elderly Chinese population, in order to find the optimal BP goal for the elderly Chinese. DESIGN AND METHOD: 1599 community-based elderly participants (age > 65 years old) were recruited in the northern Shanghai...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754001/db-02-3-strict-control-of-hypertension-in-the-elderly-with-diabetes-and-chronic-kidney-disease-pro
#2
Lawrence Appel
The identification of explicit blood pressure targets for clinical management remains controversial, particularly in older individuals with co-morbidities. Recommendations from the panel appointed to the Eighth Joint National Committee (JNC 8) and results of the SPRINT trial have rekindled interest in this issue. JNC8 recommended a higher (more relaxed) BP goal of < 150/90, instead of the traditional BP goal of <140/90, in persons aged 60+. In contrast, the recently completed SPRINT trial, which enrolled high risk patients without diabetes, documented that a lower (more stringent) SBP goal of <120 mmHg reduced total mortality and cardiovascular disease events compared to <140 mmHg...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754000/db-02-2-strict-control-of-hypertension-in-the-frail-elderly-is-it-beneficial-con
#3
Hiromi Rakugi
European guidelines (ESH-ESC2013) for the elderly have discussed well about treatment blood pressure (BP) levels and targeting BP levels. In general, elderly patients with systolic BP (SBP) ≥160 mmHg including individuals older than 80 years in good physical and mental conditions are recommended reducing SBP to between 150 and 140 mmHg. Furthermore, fit elderly patients <80 years old are recommended to consider antihypertensive treatment at SBP values ≥140 mmHg with a target SBP <140 mmHg. On the other hand, frail elderly patients are recommended to leave decisions on antihypertensive therapy to the treating physician, and based on monitoring of the clinical effects of treatment...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27642997/os-18-08-optimal-blood-pressure-goal-for-the-elderly-chinese-the-findings-from-the-northern-shanghai-study
#4
Jiadela Teliewubai, Yu-Yan Lv, Shi-Kai Yu, Bin Bai, Chen Chi, Kai Wang, Yi-Wu Zhou, Jing Xiong, Yi Zhang, Ya-Wei Xu
OBJECTIVE: The Eighth Joint National Committee Panel recommended novel blood pressure (BP) goals for individuals with hypertension, which is still under debate. We therefore assessed patients' target organ damages in controlled hypertensives defined by the Seventh or Eighth Joint National Committee thresholds (JNC7 and JNC8) in a community-based elderly Chinese population, in order to find the optimal BP goal for the elderly Chinese. DESIGN AND METHOD: 1599 community-based elderly participants (age > 65 years old) were recruited in the northern Shanghai...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27642912/db-02-3-strict-control-of-hypertension-in-the-elderly-with-diabetes-and-chronic-kidney-disease-pro
#5
Lawrence Appel
The identification of explicit blood pressure targets for clinical management remains controversial, particularly in older individuals with co-morbidities. Recommendations from the panel appointed to the Eighth Joint National Committee (JNC 8) and results of the SPRINT trial have rekindled interest in this issue. JNC8 recommended a higher (more relaxed) BP goal of < 150/90, instead of the traditional BP goal of <140/90, in persons aged 60+. In contrast, the recently completed SPRINT trial, which enrolled high risk patients without diabetes, documented that a lower (more stringent) SBP goal of <120 mmHg reduced total mortality and cardiovascular disease events compared to <140 mmHg...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27642911/db-02-2-strict-control-of-hypertension-in-the-frail-elderly-is-it-beneficial-con
#6
Hiromi Rakugi
European guidelines (ESH-ESC2013) for the elderly have discussed well about treatment blood pressure (BP) levels and targeting BP levels. In general, elderly patients with systolic BP (SBP) ≥160 mmHg including individuals older than 80 years in good physical and mental conditions are recommended reducing SBP to between 150 and 140 mmHg. Furthermore, fit elderly patients <80 years old are recommended to consider antihypertensive treatment at SBP values ≥140 mmHg with a target SBP <140 mmHg. On the other hand, frail elderly patients are recommended to leave decisions on antihypertensive therapy to the treating physician, and based on monitoring of the clinical effects of treatment...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508809/-op-lb-02-09-what-angiotensin-converting-enzyme-genotype-and-high-blood-pressure-have-in-common-in-portuguese-centenarians
#7
A Pereira Da Silva, N Ramos Marques, A Matos, A Gil, J Gorjão Clara, M Bicho
OBJECTIVE: To assess, in a sample of Portuguese Centenarians compared with a control sample of lower age individuals, the blood pressure levels, the distribution of genotypes associated with the renin-angiotensin-aldosterone axis and its association with hypertension. DESIGN AND METHOD: The study comprised 253 centenarians, with a mean age of 100.3 ± 2.0 years old, from different regions of Portugal. The control group included 268 individuals with mean age of 67...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508659/-op-3b-06-will-be-centenarians-hypertensive-individuals-how-is-the-blood-pressure-control-of-centenarians-in-portugal
#8
A Pereira Da Silva, A Matos, R Ribeiro, A Gil, J Gorjão Clara, M Pires Bicho
OBJECTIVE: To assess blood pressure (BP) levels and the prevalence of hypertension (HBP) and its control in individuals centenarians in Portugal. DESIGN AND METHOD: The study comprised a Caucasian population of 253 centenarians (77.9% women), with a mean age of 100.3 ± 2.0 years old, from different regions of Portugal. It were hypertension criteria those of ESH/ESC 2013 and or under anti hypertensive medication. Controlled BP values were considered according to JNC8...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27181996/comparative-cost-effectiveness-of-conservative-or-intensive-blood-pressure-treatment-guidelines-in-adults-aged-35-74-years-the-cardiovascular-disease-policy-model
#9
Nathalie Moise, Chen Huang, Anthony Rodgers, Ciaran N Kohli-Lynch, Keane Y Tzong, Pamela G Coxson, Kirsten Bibbins-Domingo, Lee Goldman, Andrew E Moran
The population health effect and cost-effectiveness of implementing intensive blood pressure goals in high-cardiovascular disease (CVD) risk adults have not been described. Using the CVD Policy Model, CVD events, treatment costs, quality-adjusted life years, and drug and monitoring costs were simulated over 2016 to 2026 for hypertensive patients aged 35 to 74 years. We projected the effectiveness and costs of hypertension treatment according to the 2003 Joint National Committee (JNC)-7 or 2014 JNC8 guidelines, and then for adults aged ≥50 years, we assessed the cost-effectiveness of adding an intensive goal of systolic blood pressure <120 mm Hg for patients with CVD, chronic kidney disease, or 10-year CVD risk ≥15%...
July 2016: Hypertension
https://www.readbyqxmd.com/read/25295958/optimal-targets-for-blood-pressure-control-in-chronic-kidney-disease-the-debate-continues
#10
REVIEW
John Knight, Muh Geot Wong, Vlado Perkovic
PURPOSE OF REVIEW: Because advanced chronic kidney disease (CKD) is often an exclusion criterion for large randomized trials of the management of hypertension, clinical decision making for these patients has relied on a few small, specific studies and much extrapolation. Several blood pressure treatment guidelines have recently been reissued. This review explores the applicability of the revised recommendations to CKD. RECENT FINDINGS: Many new publications are meta-analyses, guidelines and debates about guidelines...
November 2014: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/24711696/increasing-complexity-which-drug-class-to-choose-for-treatment-of-hypertension-in-the-elderly
#11
REVIEW
Edelgard Anna Kaiser, Ulrich Lotze, Hans Hendrik Schäfer
Treatment of hypertension in the elderly is expected to become more complex in the coming decades. Based on the current landscape of clinical trials, guideline recommendations remain inconclusive. The present review discusses the latest evidence derived from studies available in 2013 and investigates optimal blood pressure (BP) and preferred treatment substances. Three common archetypes are discussed that hamper the treatment of hypertension in the very elderly. In addition, this paper presents the current recommendations of the NICE 2011, JNC7 2013-update, ESH/ESC 2013, CHEP 2013, JNC8 and ASH/ISH guidelines for elderly patients...
2014: Clinical Interventions in Aging
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