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Colonic schistosomiasis

Li Fei-Yue, Tan Hong-Zhuan, Zhou Jie, Zhou Rui-Hong, Zhu Jin-Hua, Cai Xin-Ting, Ren Guang-Hui
OBJECTIVE: To understand the current distribution and characteristics of advanced schistosomiasis patients who accepted medical assistance in Hunan Province in 2015, so as to provide the evidence for perfecting the policy and measures of the medical assistance to advanced schistosomiasis patients. METHODS: The patients who had been diagnosed as advanced schistosomiasis were verified and confirmed according to the standard of the medical assistance to advanced schistosomiasis patients in Hunan Province in 2015...
March 27, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
Zou Yang, Wang Lei, Li Xiao-Li, Tian Xiao-Jun, Li Wei, An Yi-Jun, Qi Zhi-Qun, Li Jing-Jing, Wang Fei, Huang Min-Jun
OBJECTIVE: To analyze the clinical features of 6 patients with imported schistosomiasis mansoni, including the epidemic history, clinical manifestations, laboratory tests and therapeutic effect, so as to provide references for improving the levels of diagnosis and treatment of physicians. METHODS: The clinical data of 6 patients with imported schistosomiasis mansoni from January 2009 to July 2016 were collected and analyzed. RESULTS: All the 6 imported patients with schistosomiasis mansoni had a clear history of cercarial infested water exposure...
March 10, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
Leslie Raphael de Moura Ferraz, Alinne Élida Gonçalves Alves, Débora Dolores Souza da Silva Nascimento, Isabela Araújo E Amariz, Aline Silva Ferreira, Salvana Priscylla Manso Costa, Larissa Araújo Rolim, Ádley Antonini Neves de Lima, Pedro José Rolim Neto
Caused by Trypanosoma cruzi, Chagas disease is responsible for public health problems greater in magnitude than those attributed to malaria, schistosomiasis, or leishmaniasis. A factor in the socioeconomic development of poor countries, Chagas disease can cause death due to a high parasitic burden during its acute phase due and irreversible damage in organs such as the heart, esophagus, and colon during its chronic phase, even when the number of parasites is minimal. For treating Chagas disease, benznidazole (BNZ) remains the drug of choice and, in Latin America, the only drug on the market for treating the disease...
February 13, 2018: Acta Tropica
Wei Zhang, Li Chen, Qiang Wan, Yue Chen
A 77-year-old man with back pain and abdominal distention underwent F-NaF PET/CT examination to evaluate potential bone lesions. Multiple foci of increased activity were noted in the chest, which corresponded to bilateral ribs and suggested possible occult fractures. Surprisingly, increased F-NaF uptake was observed in the region of pelvis, which corresponded to calcification along the colon wall, a sequela of intestinal Japanese schistosomiasis that the patient experienced 30 years ago.
January 19, 2018: Clinical Nuclear Medicine
A Akere, A O Oluwasola, T O Fakoya, A Lawan
Intestinal Schistosomiasis is a serious disease and is commonly produced by S. mansoni and japonicum. The presence of viable ova of the organism in the colon elicits inflammation, formation of granuloma, ulcers, haemorrhage and colonic fibrosis with subsequent longterm sequelae. Schistosoma mansoni is endemic in the Middle East, Africa, Central and South America. This is a case of a Nigerian with colonic polypoid masses which turned out to be Schistosomal mansoni infection.
June 2017: Annals of Ibadan Postgraduate Medicine
L Jonas, I Bombil, A Mannell
BACKGROUND: Acute appendicitis is a very common surgical emergency. Most commonly, the histopathological findings of the appendix reflect the normal pathophysiology of appendicitis that starts with the luminal obstruction and culminates in florid suppurative, gangrenous or perforated appendix. The treatment is usually straightforward and consists of surgery and antibiotics. Uncommonly, unusual pathologies are identified and require specific management. The literature is scanty about the unusual findings...
June 2017: South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
Ayesiga M Herman, Alfred Kishe, Heri Babu, Hilary Shilanaiman, Murad Tarmohamed, Jay Lodhia, Patrick Amsi, Jeremia Pyuza, Alex Mremi, Amos Mwasamwaja, Mramba Nyindo, Kondo Chilonga, David Msuya
BACKGROUND: Colorectal cancer associated with chronic intestinal schistosomiasis has been linked with the chronic inflammation as a result of schistosomal ova deposition in the submucosal layer of the intestine. Among all species Schistosoma japonicum has been more linked to development of colorectal cancer as compared to Schistosoma mansoni due to absence of population-based studies to support the association. Despite the weak evidence, some cases have been reported associating S. mansoni with development of colorectal cancer...
August 2, 2017: World Journal of Surgical Oncology
Kongzhen Gu, Yuesheng Li, Patrick Driguez, Qingren Zeng, Xinlin Yu, Hui Sun, Liting Cai, Yongkang He, Wenyang Wang, Donald P McManus
BACKGROUND: Schistosomiasis, one of the neglected tropical diseases, is endemic in more than 70 countries. However, the clinical diagnosis of patients with a low degree of infection is an unsolved technical problem. In areas endemic for schistosomiasis japonica, proctoscopy detection of eggs has been one method used for clinical diagnosis. However, it is often a challenge to find typical live eggs and it is difficult to distinguish live eggs from large numbers of partially degraded and/or completely degraded eggs within colon biopsy tissue...
April 4, 2017: BMC Infectious Diseases
Sanaa Al Rehily, Reham Kaki, Fahad Al Ghamdi, Dalia El-Hossary
INTRODUCTION: Amoebiasis is the third most frequent cause of mortality after malaria and schistosomiasis. In developed countries, amebiasis is also seen in migrants who have travelled to endemic areas. The factors responsible for its progression from intestinal amebiasis to an amebic liver abscess are not fully understood. CASE PRESENTATION: A 54-year-old man presented with abdominal pain, fever and diarrhoea. Laparotomy confirmed an inflammatory mass involving the right colon, and he underwent a right hemicolectomy...
June 2016: JMM Case Reports
Thein Swe, Aama Baqui, Akari Thein Naing, Tajruba Baqui, Jagannath Sherigar, Mohamed Mansour
Schistosomiasis is an important parasitic disease with various clinical presentations caused by trematode blood flukes. It can present with asymptomatic, chronic colonic ulcerations, strictures, or inflammatory mass causing bowel obstruction. Intestinal polyps are uncommon and induced by antigens released from the schistosome eggs that trigger a cell-mediated inflammatory response with granuloma formation involving T cells, macrophages, and necrosis. This is very relevant while evaluating chronic intermittent gastrointestinal symptoms and eosinophilia in an immigrant patient from endemic areas of schistosomiasis...
2016: Journal of Community Hospital Internal Medicine Perspectives
Xing-Quan Wang, Feng-Peng Wang, Wei Chen, Jun Huang, Kateryna Bazaka, Kostya Ken Ostrikov
Schistosoma japonicum is a widespread human and animal parasite that causes intestinal and hepatosplenic schistosomiasis linked to colon, liver and bladder cancers, and anemia. Estimated 230 million people are currently infected with Schistosoma spp, with 779 million people at risk of contracting the parasite. Infection occurs when a host comes into contact with cercariae, a planktonic larval stage of the parasite, and can be prevented by inactivating the larvae, commonly by chemical treatment. We investigated the use of physical non-equilibrium plasma generated at atmospheric pressure using custom-made dielectric barrier discharge reactor to kill S...
October 14, 2016: Scientific Reports
Joachim Richter, Daniel Azoulay, Yi Dong, Martha C Holtfreter, Robert Akpata, Julien Calderaro, Tarik El-Scheich, Matthias Breuer, Andreas Neumayr, Christoph Hatz, Gerald Kircheis, Monica C Botelho, Christoph F Dietrich
After malaria, schistosomiasis remains the most important tropical parasitic disease in large parts of the world. Schistosomiasis has recently re-emerged in Southern Europe. Intestinal schistosomiasis is caused by most Schistosoma (S.) spp. pathogenic to humans and leads to chronic inflammation and fibrosis of the colon as well as to liver fibrosis. Gallbladder abnormalities usually occur in patients with advanced hepatic portal fibrosis due to Schistosoma mansoni infection. Occasionally, gallbladder abnormalities have been seen also in children and occurring without associated overt liver abnormalities...
August 2016: Parasitology Research
Jin Imai, Hitoshi Ichikawa, Hajime Mizukami, Takayoshi Suzuki, Norihito Watanabe, Tetsuya Mine
We reported a case of sigmoid colonic high grade tubular adenomas associated with deposited ova of Schistosoma japonicum. A 76-year-old Japanese man was referred to our colonoscopy due to a positive fecal occult blood test. He had a medical history of schistosomiasis japonica. The colonoscopy revealed that there were two sigmoid colon polyps, approximately 8 mm in diameter. These were removed by endoscopic mucosal resection (EMR). Pathological examination revealed high grade tubular adenomas and deposited some ova of Schistosoma japonicum with severe fibrotic change and granuloma formation in the submucosal layer...
March 20, 2016: Tokai Journal of Experimental and Clinical Medicine
Vikas Nath, Mithra Baliga
We report a case of adenocarcinoma metastatic to the abdominal wall in a 71-year-old man with a history of primary bladder adenocarcinoma. CT-guided core biopsy was performed; imprints and histologic sections showed malignant glands lined by tumor cells with hyperchromatic nuclei and prominent nucleoli, infiltrating through skeletal muscle. Immunohistochemistry revealed positivity for CK7, membranous/cytoplasmic β-catenin, caudal-type homeobox transcription factor 2 (CDX2), and α-methylacyl coenzyme A racemase and negativity for CK20, p63, prostate-specific antigen (PSA), and prostate-specific acid phosphatase (PSAP)...
2016: Case Reports in Pathology
Wei-en Zhou, An-hua Yin, Yong-yuan Pu, Jun-yuan Feng
OBJECTIVE: To understand the status of treatment and assistance for advanced schistosomiasis patients in Changshu City from 2006 to 2014. METHODS: According to The Parasitic Disease Prevention Information Management System, the data of treatment and assistance for advanced schistosomiasis patients were collected and analyzed statistically in Changshu City from 2006 to 2014. RESULTS: A total of 269 advanced schistosomiasis patients were assisted...
August 2015: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
Dalia S Ashour, Zeinab S Shohieb, Naglaa I Sarhan
Role of different mediators was described in the development of the granulomatous response and fibrosis observed in intestinal schistosomiasis. However, both Toll-like receptor 2 (TLR2) and nuclear factor kappa B (NF-κB) have not yet been investigated in intestinal schistosomiasis. This study aimed to characterize the role of TLR2 and NF-κB in the pathogenesis of intestinal schistosomiasis. Experimental animals were divided into two groups; group I: non-infected control group and group II: mice infected subcutaneously with S...
November 2015: Journal of Advanced Research
Biswajit Biswas, Deepak Vedant, Vijay Kaushal, Pooja Chauhan, Tanish Mandal, Nidhi Raina, Brij Sharma
No abstract text is available yet for this article.
October 2015: Indian Journal of Pathology & Microbiology
Frederik Van den Broeck, Gregory E Maes, Maarten H D Larmuseau, David Rollinson, Ibrahima Sy, Djibril Faye, Filip A M Volckaert, Katja Polman, Tine Huyse
BACKGROUND: Anthropogenic environmental changes may lead to ecosystem destabilization and the unintentional colonization of new habitats by parasite populations. A remarkable example is the outbreak of intestinal schistosomiasis in Northwest Senegal following the construction of two dams in the '80s. While many studies have investigated the epidemiological, immunological and geographical patterns of Schistosoma mansoni infections in this region, little is known about its colonization history...
August 2015: PLoS Neglected Tropical Diseases
Hao Feng, Ai-Guo Lu, Xue-Wei Zhao, Ding-Pei Han, Jing-Kun Zhao, Lei Shi, Tobias S Schiergens, Serene M L Lee, Wen-Peng Zhang, Wolfgang E Thasler
AIM: To compare the clinicopathological features of patients with non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer. METHODS: All the patients with rectosigmoid carcinoma who underwent laparoscopic radical surgical resection in the Shanghai Minimally Invasive Surgical Center at Ruijin Hospital affiliated to Shanghai Jiao-Tong University between October 2009 and October 2013 were included in this study. Twenty-six cases of colonic schistosomiasis diagnosed through colonoscopy and pathological examinations were collected...
June 21, 2015: World Journal of Gastroenterology: WJG
Elizabeth M Hechenbleikner, Jennifer A McQuade
Over one billion people worldwide harbor intestinal parasites. Parasitic intestinal infections have a predilection for developing countries due to overcrowding and poor sanitation but are also found in developed nations, such as the United States, particularly in immigrants or in the setting of sporadic outbreaks. Although the majority of people are asymptomatically colonized with parasites, the clinical presentation can range from mild abdominal discomfort or diarrhea to serious complications, such as perforation or bleeding...
June 2015: Clinics in Colon and Rectal Surgery
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