Dan Han, Xinyue Chang, Dan Xu, Jizhong Shen, Ali Fan, Meihua Wang, Dingran Li, Xiangkai Chen, Cheng Wang, Yi Wu, Zhaocong Yang, Jian Li, Siliang Wang
BACKGROUND: Yi-Qi-Huo-Xue Decoction (YQHXD), a traditional Chinese medicine formula, has demonstrated efficacy in the clinical treatment of intracerebral hemorrhage (ICH) for over a decade. Nevertheless, the precise pharmacotherapeutic compounds of YQHXD capable of penetrating into cerebral tissue and the pharmacological underpinnings of YQHXD remain ambiguous. METHODS: The active components of YQHXD in rat brains was analyzed by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry...
February 19, 2024: Phytomedicine