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M Malvezzi, G Carioli, P Bertuccio, P Boffetta, F Levi, C La Vecchia, E Negri
Background: We projected cancer mortality statistics for 2018 for the European Union (EU) and its six more populous countries, using the most recent available data. We focused on colorectal cancer. Materials and methods: We obtained cancer death certification data from stomach, colorectum, pancreas, lung, breast, uterus, ovary, prostate, bladder, leukaemia, and total cancers from the World Health Organisation database and projected population data from Eurostat...
March 19, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
Katarzyna Wyskida, Jarosław Wajda, Dariusz Klein, Joanna Witkowicz, Rafał Ficek, Sylwia Rotkegel, Urszula Spiechowicz-Zatoń, Joanna Kocemba-Dyczek, Jarosław Ciepał, Magdalena Olszanecka-Glinianowicz, Andrzej Więcek, Jerzy Chudek
BACKGROUND: Diet is a key factor that determines proper alignment of calcium-phosphate and nutritional status among hemodialysis (HD) patients. OBJECTIVES: To assess the nutrient intake in relation to long-term calcium-phosphate control in HD patients with end-stage renal failure. MATERIAL AND METHODS: The study included 107 patients (66 men, 41 women) from 10 dialysis centers in the Upper Silesia region of Poland. To analyze the diet composition during the previous year, a portion-sized version of the Diet History Questionnaire II (DHQ-II) from National Institutes of Health was used...
February 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Karolina Zarychta, Carina K Y Chan, Magdalena Kruk, Aleksandra Luszczynska
PURPOSE: Theoretical models, such as the transdiagnostic model of eating disorders highlight the role of cognitive factors (e.g., the way people perceive their bodies) and their associations with maladaptive weight management behaviors resulting in underweight. This paper aims at testing the indirect association of adolescent's body satisfaction and body mass index (BMI) through restrictive dieting, healthy eating or unhealthy eating as well as moderating role of adolescent's weight status...
March 8, 2018: Eating and Weight Disorders: EWD
Anna Galczak-Kondraciuk, Paweł Stempel, Jan Czeczelewski
Background: Children and youth constitute a group that is particularly prone to the effects of improper diet. In the puberty period, numerous significant lifestyle choices are made, for instance regarding particular nutritional behaviours which may be repeated later in life and may determine the state of health. Objective: The aim of the study was to assess nutritional behaviours of children aged 7-12 attending to primary schools in Biala Podlaska county (Eastern Region of Poland)...
2018: Roczniki Państwowego Zakładu Higieny
He-Ping Chen, Zhen-Zhu Zhao, Zheng-Hui Li, Ying Huang, Shuai-Bing Zhang, Yang Tang, Jian-Neng Yao, Lin Chen, Masahiko Isaka, Tao Feng, Ji-Kai Liu
This study features the isolation and identification of twelve lanostane-type triterpenoids, namely lepiotaprocerins A-L (1-12), from the fruiting bodies of Poland-collected edible mushroom Macrolepiota procera. Their structures as well as absolute configurations were ambiguously established by extensive spectroscopic analyses, ECD calculation, and single crystal X-ray diffraction analyses. Structurally, lepiotaprocerins A-F (1-6) are distinguished by the presence of a rare "1-en-1,11-epoxy" moiety which have not been previously described in the lanostane class...
March 6, 2018: Journal of Agricultural and Food Chemistry
Stefanos Tyrovolas, Noe Garin Escriva, Jose Luis Ayuso-Mateos, Somnath Chatterji, Ai Koyanagi, Marta Miret, Moneta Victoria, Beatriz Olaya, Beata Tobiasz-Adamczyk, Seppo Koskinen, Matilde Leonardi, Josep Maria Haro
BACKGROUND AND AIM: Frailty is characterized by several deficits in multiple health related domains. Although cognition is among the important components of frailty, there is lack of evidence on the role of specific neuro-cognitive dimensions. The primary aim of the present work was to evaluate the multidimensional definition of frailty, and to assess whether neuro-cognitive function is a constituent of the frailty syndrome among adults aged ≥50 years living in three European countries...
February 27, 2018: Experimental Gerontology
Tomasz Stenzel, Daria Dziewulska, Brejnev M Muhire, Penelope Hartnady, Simona Kraberger, Darren P Martin, Arvind Varsani
Circoviruses are circular single-stranded DNA (ssDNA) viruses that infect a variety of animals, both domestic and wild. Circovirus infection in birds is associated with immunosuppression and this in turn predisposes the infected animals to secondary infections that can lead to mortality. Farmed geese ( Anser anser ) in many parts of the world are infected with circoviruses. The majority of the current genomic information for goose circoviruses (GoCVs) ( n = 40) are from birds sampled in China and Taiwan, and only two genome sequences are available from Europe (Germany and Poland)...
March 2, 2018: Viruses
Jennifer A Whitaker, Caroline M Poland, Thomas J Beckman, John B Bundrick, Rajeev Chaudhry, Diane E Grill, Andrew J Halvorsen, Jill M Huber, Mary J Kasten, Karen F Mauck, Ramila A Mehta, Timothy Olson, Kris G Thomas, Matthew R Thomas, Abinash Virk, Majken T Wingo, Gregory A Poland
PURPOSE: The aims of this study are to evaluate the impact of a novel immunization curriculum based on the Preferred Cognitive Styles and Decision Making Model (PCSDM) on internal medicine (IM) resident continuity clinic patient panel immunization rates, as well as resident immunization knowledge, attitudes, and practices (KAP). METHODS: A cluster-randomized controlled trial was performed among 143 IM residents at Mayo Clinic to evaluate the PCSDM curriculum plus fact-based immunization curriculum (intervention) compared to fact-based immunization curriculum alone (control) on the outcomes of resident continuity clinic patient panel immunization rates for influenza, pneumococcal, tetanus, pertussis, and zoster vaccines...
February 26, 2018: Vaccine
Piotr Grabarczyk, Ewa Sulkowska, Jolanta Gdowska, Aneta Kopacz, Grzegorz Liszewski, Dorota Kubicka-Russel, Sally A Baylis, Victor M Corman, Ewa Noceń, Dariusz Piotrowski, Jolanta Antoniewicz-Papis, Magdalena Łętowska
BACKGROUND: Until now, markers of hepatitis E virus (HEV) infection have not been studied in blood donors throughout Poland, and no acute case of HEV infection has been closely documented or confirmed by HEV RNA detection. The prevalence of HEV infection markers, including HEV RNA in Polish blood donors and virus genotypes was investigated. STUDY DESIGN AND METHODS: In total, 12,664 individual donations from 22 Polish blood transfusion centers were tested for HEV RNA by transcription-mediated amplification...
March 1, 2018: Transfusion
Tomasz Kluz, Andrzej Jasiewicz, Elżbieta Marczyk, Robert Jach, Anna Jakubowska, Jan Lubiński, Steven A Narod, Jacek Gronwald
Background: Causative variants in BRCA1 and BRCA2 are well-established risk factors for breast and ovarian cancer. In Poland, the causative founder variants in the BRCA1 are responsible for a significant proportion of ovarian cancer cases, however, regional differences in the frequencies of various mutations may exist. The spectrum and frequency of BRCA1/2 mutations between ovarian cancer patients have not yet been studied in the region of South-East Poland. Methods: We examined 158 consecutive unselected cases of ovarian cancer patients from the region of Podkarpacie...
2018: Hereditary Cancer in Clinical Practice
Małgorzata Misztal-Szkudlińska, Elżbieta Kalisińska, Piotr Szefer, Piotr Konieczka, Jacek Namieśnik
This work analyses the effect of mercury on the condition of cormorants (Phalacrocorax carbo) from an extensive breeding colony in northern Poland, the largest in Europe. A total of 55 birds (44 adults and 11 immature) were obtained. Total mercury (Hg) concentrations were measured in the liver, kidneys, breast muscles, heart, gullet (oesophagus), stomach, intestines, trachea, lungs and eyeballs. The total body mass (TBM) and empty body mass (EBM) were measured, and the body parts taken for analysis were weighed...
February 16, 2018: Ecotoxicology and Environmental Safety
A S Olesen, L Lohse, A Boklund, T Halasa, G J Belsham, T B Rasmussen, A Bøtner
Since the introduction of African swine fever virus (ASFV) into the Baltic states and Poland in 2014, the disease has continued to spread within these regions. In 2017, the virus spread further west and the first cases of disease were reported in the Czech Republic and Romania, in wild boar and domestic pigs, respectively. To control further spread, knowledge of different modes of transmission, including indirect transmission via a contaminated environment, is crucial. Up until now, such an indirect mode of transmission has not been demonstrated...
February 19, 2018: Transboundary and Emerging Diseases
G Franzo, M Legnardi, C K Hjulsager, F Klaumann, L E Larsen, J Segales, M Drigo
Porcine circovirus 3 (PCV3) is a new species of the Circovirus genus, which has recently been associated with different clinical syndromes. Its presence has been reported in different countries of North and South America, Asia and recently also Europe (Poland). However, different from the other continents, no European PCV3 sequence is currently available in public databases. There is a strong need of epidemiological data and full-genome sequences from Europe because of its relevance in the understanding of PCV3 molecular epidemiology and control...
February 16, 2018: Transboundary and Emerging Diseases
Dorota Zarębska-Michaluk, Robert Flisiak, Jerzy Jaroszewicz, Ewa Janczewska, Agnieszka Czauż-Andrzejuk, Hanna Berak, Andrzej Horban, Agnieszka Staniaszek, Andrzej Gietka, Magdalena Tudrujek, Krzysztof Tomasiewicz, Dorota Dybowska, Waldemar Halota, Anna Piekarska, Marek Sitko, Aleksander Garlicki, Iwona Orłowska, Krzysztof Simon, Teresa Belica-Wdowik, Barbara Baka-Ćwierz, Włodzimierz Mazur, Jolanta Białkowska, Łukasz Socha, Marta Wawrzynowicz-Syczewska, Łukasz Laurans, Zbigniew Deroń, Beata Lorenc, Beata Dobracka, Olga Tronina, Małgorzata Pawłowska
The aim of the study is to analyze treatments available for patients infected with genotype (G) 3 hepatitis C virus (HCV) in Poland at the beginning of the interferon (IFN)-free era and evaluate the efficacy and safety of different therapeutic options administered in a real-world setting. We analyzed data of 198 patients who started antiviral therapy after July 1, 2015, and completed it before December 31, 2016; 57.6% of them had liver cirrhosis and 46% were treatment experienced. Fifty percent of patients were assigned to sofosbuvir (SOF)+pegylated IFN alfa (PegIFNa)+ribavirin (RBV), 9% to PegIFNa+RBV, 36% received SOF+RBV, and 5% SOF+daclatasvir (DCV)±RBV...
February 2018: Journal of Interferon & Cytokine Research
Dominika Kanikowska, Dorota Sikorska, Barbara Kuczyńska, Marian Grzymisławski, Andrzej Bręborowicz, Janusz Witowski
BACKGROUND: The components of lifestyle of medical students, with comprehensive reporting of their physical activity and drinking and eating behavior, are rarely evaluated. Being overweight (increased body mass index - BMI) is associated with health problems, an unhealthy lifestyle (inadequate sleep, diet and exercise) being implicated. OBJECTIVES: The aim was to determine if there were discrepancies between assessments of actual lifestyle and advice regarding the principles of a healthy lifestyle...
December 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Ryszard Piotrowicz, Paweł Krzesiński, Paweł Balsam, Maciej Kempa, Renata Główczyńska, Marcin Grabowski, Łukasz Kołtowski, Ewa Lewicka, Michał Peller, Ewa Piotrowicz, Jakub Podolec, Adam Stańczyk, Justyna Zajdel, Grzegorz Opolski
For several years, we have observed the dynamic development of technologies that allow patients to access medical care from the comfort of their homes, without direct contact with the doctor. Innovative solutions based on telemedicine improve care coordination and communication among clinicians, patients, and their families, as well as increases patients' security and gives them greater independence, thus eliminating health care inequalities. The rapidly growth of telemedicine and the adoption of new technologies in clinical practice is also observed in Poland...
February 14, 2018: Kardiologia Polska
Malgorzata Węgiel, Ryszard Chrząszcz, Anna Maślanka, Adam Grochowalski
The transfer of dioxin from the environment to the food is a problem in a consumers' health protection. The study aimed to determine the concentration of dioxins in free-range chicken eggs, air and soil samples, collected during 12 months on an individual small farm, located in Małopolska region, Poland. In the majority of analyzed eggs, the concentrations of dioxin exceeded several times the legal limit of 2.5 pg WHO-TEQ g-1fat. Seasonal changes in the PCDD/Fs congeners in egg, air and soil samples were studied...
February 3, 2018: Chemosphere
Lisa G Shaffer, Christina J Ramirez, Patricia Phelps, Maya Aviram, Marta Walczak, Gila Kahila Bar-Gal, Blake C Ballif
Genetic diseases occur in breeds used for law enforcement. As important team members, dogs are expected to operate at peak performance for several years and are significant investments for both the initial purchase and extensive, specialized training. Previous studies have not focused on causes for retirement or euthanasia as genetic (inherited) versus acquired (environmental). We performed direct mutational analysis for breed-specific conditions on samples from 304 dogs including 267 law enforcement (122 US, 87 Israeli, and 58 Polish) and 37 search and rescue dogs...
February 9, 2018: Cytogenetic and Genome Research
G Oskay-Özcelik, S Alavi, R Richter, M Keller, S C Cecere, G Cormio, F Joly, J E Kurtz, A du Bois, M Maciejewski, M Jedryka, I Vergote, E Van Nieuwenhuysen, A Casado, C Mendiola, P Achimas-Cadariu, C Vlad, D Reimer, A G Zeimet, M Friedlander, J Sehouli
Backround: The primary aim of this study was to investigate information needs and treatment preferences of patients with ovarian cancer, focusing especially on physician-patient relationship and treatment. Patients and methods: A questionnaire was developed based on the experiences of the national German survey Expression II, and was provided to patients with ovarian cancer either at initial diagnosis or with recurrent disease via Internet (online-version) or as print-out-version...
February 5, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
Gregory A Poland, Richard B Kennedy, Inna G Ovsyannikova, Ricardo Palacios, Paulo Lee Ho, Jorge Kalil
Zika virus is an emerging pathogen of substantial public health concern to human beings. Although most infections are asymptomatic or present with benign, self-limited symptoms, a small percentage of patients have complications, such as congenital anomalies in the developing fetus of pregnant women infected with the virus and neurological complications (eg, Guillain-Barré syndrome). To date, there is no vaccine, antiviral drug, or other modality available to prevent or treat Zika virus infection. In this Review, we examine vaccine development efforts for Zika virus to date and research gaps in the development of candidate vaccines against Zika virus...
January 25, 2018: Lancet Infectious Diseases
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