R Contreras-Omaña, J A Velarde-Ruiz Velasco, G E Castro-Narro, O Trujillo-Benavides, F Zamarripa-Dorsey, A A Reyes-Dorantes, L Muñoz-Espinosa, I Aiza-Haddad, M Castillo-Barradas, E Cerda-Reyes, L E Cisneros-Garza, J Flores-Calderón, E S García-Jiménez, M F Higuera-de-la-Tijera, M A Lira-Pedrín, E Marquez-Guillén, C Moctezuma-Velázquez, R Moreno-Alcántar, S G Noyola-Cedillo, J L Pérez-Hernández, M V Ramos-Gómez, J M Remes-Troche, M T Rizo-Robles, H Rodríguez-Hernández
The term cholestasis refers to bile acid retention, whether within the hepatocyte or in the bile ducts of any caliber. Biochemically, it is defined by a level of alkaline phosphatase that is 1.67-times higher than the upper limit of normal. Cholestatic diseases can be associated with an inflammatory process of the liver that destroys hepatocytes (hepatitis), withjaundice (yellowing of the skin and mucus membranes, associated with elevated serum bilirubin levels), or with both, albeit the three concepts should not be considered synonymous...
2022: Revista de Gastroenterología de México