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https://www.readbyqxmd.com/read/29050285/high-dose-atorvastatin-reduces-the-risk-of-cardiovascular-events-in-patients-with-percutaneous-coronary-intervention
#1
Changqing Lu, Helei Jia, Zhentao Wang
We systematically searched in PubMed, Web of Science, Embase and China National Knowledge Infrastructure from the inception to March 31, 2017, identified relevant trials about efficacy of high-does Atorvastatin for patients with percutaneous coronary intervention. Twelve studies with the number of 2801 patients were included in the meta-analysis. Compared with control group, high-does Atorvastatin significantly reduced the risk of myocardial infarction in patients with percutaneous coronary intervention (Relative risk =0...
September 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29050054/indication-criteria-for-total-knee-arthroplasty-in-patients-with-osteoarthritis-a-multi-perspective-consensus-study
#2
Jochen Schmitt, Toni Lange, Klaus-Peter Günther, Christian Kopkow, Elisabeth Rataj, Christian Apfelbacher, Martin Aringer, Eckhardt Böhle, Hartmut Bork, Karsten Dreinhöfer, Niklaus Friederich, Karl-Heinz Frosch, Sascha Gravius, Erika Gromnica-Ihle, Karl-Dieter Heller, Stephan Kirschner, Bernd Kladny, Hendrik Kohlhof, Michael Kremer, Nicolai Leuchten, Maike Lippmann, Jürgen Malzahn, Heiko Meyer, Rainer Sabatowski, Hanns-Peter Scharf, Johannes Stoeve, Richard Wagner, Jörg Lützner
Background and Objectives Knee osteoarthritis (OA) is a significant public health burden. Rates of total knee arthroplasty (TKA) in OA vary substantially between geographical regions, most likely due to the lack of standardised indication criteria. We set out to define indication criteria for the German healthcare system for TKA in patients with knee OA, on the basis of best evidence and transparent multi-stakeholder consensus. Methods We undertook a complex mixed methods study, including an iterative process of systematic appraisal of existing evidence, Delphi consensus methods and stakeholder conferences...
October 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29050030/concluding-remarks
#3
Marcela Rocha de Olivera Carrilho
Case reports and clinical trials conducted in different countries (i.e., the United States, Canada, Brazil, Germany, Finland, Sweden, Japan, India, and Sri Lanka) tend to find a positive relationship between the presence of more retained teeth in older ages and the prevalence of root caries in older adults. As this tendency has been shown to prevail globally, it is estimated that the predicted demographic elderly expansion may cause, in near future, a significant increment in the number of older population requiring an effective means of preventing and treating root surface caries...
2017: Monographs in Oral Science
https://www.readbyqxmd.com/read/29049971/food-addiction-prevalence-psychopathological-correlates-and-associations-with-quality-of-life-in-a-large-sample
#4
Paulo R Nunes-Neto, Cristiano A Köhler, Felipe B Schuch, Marco Solmi, João Quevedo, Michael Maes, Andrea Murru, Eduard Vieta, Roger S McIntyre, Susan L McElroy, Ashley N Gearhardt, Brendon Stubbs, André F Carvalho
OBJECTIVE: To determine the prevalence of food addiction in a large Brazilian non-clinical sample. Sociodemographic and psychopathological correlates of food addiction as well as associations with quality (QoL) domains were also investigated. METHODS: This cross-sectional study obtained data from a Brazilian anonymous web-based research platform (N = 7639; 71.3% females). Participants provided sociodemographic data and completed the modified Yale Food Addiction Scale 2...
October 12, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29049899/intraosseous-hemangioma-of-the-frontal-bone-report-of-a-case-and-review-of-the-literature
#5
Joshua S Brandner, Yeshwant B Rawal, Louis J Kim, Jasjit K Dillon
Intraosseous hemangiomas of the maxillofacial region are rare lesions that constitute less than 1% of all osseous tumors. A review of the literature on intraosseous hemangiomas of the skull and facial bones showed a limited number of publications, much of which were largely limited to case reports. This case report summarizes the workup and surgical treatment of a 39-year-old woman with an intraosseous hemangioma of the left frontal bone. The histology, treatment, and literature are reviewed.
September 23, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29049784/hormonal-manipulation-after-surgery-for-catamenial-pneumothorax
#6
Megan Garner, Eltayeb Ahmed, Sarah Gatiss, Douglas West
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was whether hormonal manipulation with gonadotrophin-releasing hormone analogues reduces the risk of recurrent catamenial pneumothorax after surgery, compared with surgery alone. Altogether 819 papers were found using the reported search, of which 7 represented the best evidence to answer the clinical question. The authors, date, journal, country of publication, study type, level of evidence, patient group studied, relevant outcomes and results of these papers are tabulated...
September 28, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049755/is-ministernotomy-superior-to-right-anterior-minithoracotomy-in-minimally-invasive-aortic-valve-replacement
#7
Damian Balmforth, Amer Harky, Kulvinder Lall, Rakesh Uppal
A best evidence topic was constructed according to a structured protocol. The question addressed was whether, in patients undergoing minimally invasive aortic valve replacement (AVR), right anterior thoracotomy (RT) or mini-sternotomy (MS) was superior in terms of postoperative outcome? A total of 840 publications were found using the reported search. Of these, 6 represented the best available evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated...
August 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049705/follow-up-of-a-simple-method-for-aortic-valve-reconstruction-with-fixed-pericardium-in-children
#8
Amir-Reza Hosseinpour, Alejandro Adsuar-Gómez, Antonio González-Calle, Antonio Moruno-Tirado, Francisco García-Angleu, Israel Valverde, Felix Coserria-Sánchez, Begoña Manso-García
In 2013, we published a simple method for aortic valve reconstruction in children using fixed pericardium in this journal. This was not expected to be a durable solution but a temporizing measure in the absence of other solutions, in order to buy time for growth that would allow subsequent prosthetic valve insertion. As such, this was implemented in 3 patients with excellent immediate results, as reported in our original publication. We are now writing to provide longer term information. In 2 cases, a newborn and a 12-year-old boy, the valve calcified heavily at 4 years' follow-up...
July 21, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049667/when-can-computed-tomography-fissure-analysis-replace-chartis-collateral-ventilation-assessment-in-the-prediction-of-patients-with-emphysema-who-might-benefit-from-endobronchial-valve-therapy
#9
Alfonso Fiorelli, Mario Santini, Pallav Shah
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was when can computed tomography-fissure analysis replace Chartis collateral ventilation assessment in the prediction of patients with emphysema who might benefit from endobronchial valve therapy? Twelve papers were chosen to answer the question. The authors, date, journal, country of publication and study type; patient group studied; relevant outcomes and results of these papers were tabulated. Five studies retrospectively compared the prognostic value of 2 methods...
September 5, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29049553/evaluating-industry-payments-among-dermatology-clinical-practice-guidelines-authors
#10
Jake X Checketts, Matthew Thomas Sims, Matt Vassar
Importance: It is well documented that financial conflicts of interest influence medical research and clinical practice. Prior to the Open Payments provisions of the Affordable Care Act, financial ties became apparent only through self-disclosure. The nature of financial interests has not been studied among physicians who develop dermatology clinical practice guidelines. Objective: To evaluate payments received by physicians who author dermatology clinical practice guidelines, compare disclosure statements for accuracy, determine whether pharmaceutical companies from which the authors received payments manufactured products related to the guidelines, and examine the extent to which the American Academy of Dermatology enforced their Administrative Regulations for guideline development...
October 18, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/29049279/knowledge-attitudes-and-practices-related-to-ebola-virus-disease-at-the-end-of-a-national-epidemic-guinea-august-2015
#11
Mohamed F Jalloh, Susan J Robinson, Jamaica Corker, Wenshu Li, Kathleen Irwin, Alpha M Barry, Paulyne Ngalame Ntuba, Alpha A Diallo, Mohammad B Jalloh, James Nyuma, Musa Sellu, Amanda VanSteelandt, Megan Ramsden, LaRee Tracy, Pratima L Raghunathan, John T Redd, Lise Martel, Barbara Marston, Rebecca Bunnell
Health communication and social mobilization efforts to improve the public's knowledge, attitudes, and practices (KAP) regarding Ebola virus disease (Ebola) were important in controlling the 2014-2016 Ebola epidemic in Guinea (1), which resulted in 3,814 reported Ebola cases and 2,544 deaths.* Most Ebola cases in Guinea resulted from the washing and touching of persons and corpses infected with Ebola without adequate infection control precautions at home, at funerals, and in health facilities (2,3). As the 18-month epidemic waned in August 2015, Ebola KAP were assessed in a survey among residents of Guinea recruited through multistage cluster sampling procedures in the nation's eight administrative regions (Boké, Conakry, Faranah, Kankan, Kindia, Labé, Mamou, and Nzérékoré)...
October 20, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29049278/illicit-drug-use-illicit-drug-use-disorders-and-drug-overdose-deaths-in-metropolitan-and-nonmetropolitan-areas-united-states
#12
Karin A Mack, Christopher M Jones, Michael F Ballesteros
PROBLEM/CONDITION: Drug overdoses are a leading cause of injury death in the United States, resulting in approximately 52,000 deaths in 2015. Understanding differences in illicit drug use, illicit drug use disorders, and overall drug overdose deaths in metropolitan and nonmetropolitan areas is important for informing public health programs, interventions, and policies. REPORTING PERIOD: Illicit drug use and drug use disorders during 2003-2014, and drug overdose deaths during 1999-2015...
October 20, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29049231/dose-duration-and-strain-of-bacillus-calmette-guerin-in-the-treatment-of-nonmuscle-invasive-bladder-cancer-meta-analysis-of-randomized-clinical-trials
#13
Yongjun Quan, Chang Wook Jeong, Cheol Kwak, Hyeon Hoe Kim, Hyung Suk Kim, Ja Hyeon Ku
BACKGROUND: Intravesical bacillus Calmette-Guerin (BCG) instillation is widely used as an adjuvant therapy after transurethral resection of bladder tumor (TURBT) in patients with intermediate- and high-risk nonmuscle invasive bladder cancer (NMIBC). However, the effective dose, duration, and strain of BCG have not yet been clearly determined. We aimed to elucidate the relationship between dose, duration, and strain of BCG and clinical outcomes in NMIBC patients treated with TURBT. METHODS: We conducted a literature search in Embase, Scopus, and PubMed databases for all relevant articles published up to October 2016 in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis guidelines...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29049014/transcriptomic-guided-drug-repositioning-supported-by-a-new-bioinformatics-search-tool-genexpharma
#14
Beste Turanli, Gizem Gulfidan, Kazim Yalcin Arga
Drug repositioning is an innovative approach to identify new therapeutic indications for existing drugs. Drug repositioning offers the promise of reducing drug development timeframes and costs, and because it involves drugs that are already in the clinic, it might remedy some of the drug safety challenges traditionally associated with drug candidates that are not yet available in the clinic. The gene-by-drug interactions are an important dimension of optimal drug repositioning and development strategies. While gene-by-drug interactions have been curated and presented in various databases, novel bioinformatics tools and approaches are timely, and required with a specific focus to support drug positioning...
October 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/29048984/development-of-middle-east-respiratory-syndrome-coronavirus-vaccines-advances-and-challenges
#15
Heeyoun Cho, Jean-Louis Excler, Jerome H Kim, In-Kyu Yoon
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is an emerging pathogen with the potential to pose a threat to global public health. Sporadic cases and outbreaks continue to be reported in the Middle East, and case fatality rates remain high at approximately 36% globally. No specific preventive or therapeutic countermeasures currently exist. A safe and effective vaccine could play an important role in protecting against the threat from MERS-CoV. This review discusses human vaccine candidates currently under development, and explores viral characteristics, molecular epidemiology and immunology relevant to MERS-CoV vaccine development...
October 19, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29048980/the-2016-lifetime-immunization-schedule-approved-by-the-italian-scientific-societies-a-new-paradigm-to-promote-vaccination-at-all-ages
#16
Paolo Bonanni, Giampietro Chiamenti, Giorgio Conforti, Tommasa Maio, Anna Odone, Rocco Russo, Silvestro Scotti, Carlo Signorelli, Alberto Villani
Medical scientific societies have the core mission of producing, pooling and disseminating solid and updated scientific information. We report the successful experience of the partnership of four national Medical Scientific Societies active in Italy in producing scientific advice on vaccines and vaccination. In particular, i) the Italian Society of Hygiene, Preventive Medicine and Public Health; SitI, ii) the Italian Society of Paediatrics; SIP, ii) the Italian Federation of Family Paediatricians; FIMP, and iv) the Italian Federation of General Medicine FIMMG) have worked together since 2012 to produce shared evidence-based recommendations on vaccination schedules, namely the "Lifetime Immunization Schedule" which introduced for the first time in Italy a life-course approach to vaccination...
October 19, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29048969/school-based-curriculum-to-improve-depression-literacy-among-us-secondary-school-students-a-randomized-effectiveness-trial
#17
Karen Swartz, Rashelle J Musci, Mary Beth Beaudry, Kathryn Heley, Leslie Miller, Clarissa Alfes, Lisa Townsend, Graham Thornicroft, Holly C Wilcox
OBJECTIVES: To determine the effectiveness of a universal school-based depression education program. METHODS: In 2012-2015, we matched 6679 students from 66 secondary schools into pairs by state (Maryland, Delaware, Pennsylvania, Michigan, and Oklahoma) and randomized to the Adolescent Depression Awareness Program (ADAP; n = 3681) or to a waitlist control condition (n = 2998). Trained teachers delivered ADAP as part of the health education curriculum to students aged 14 to 15 years...
October 19, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29048967/new-and-recurrent-concussions-in-high-school-athletes-before-and-after-traumatic-brain-injury-laws-2005-2016
#18
Jingzhen Yang, R Dawn Comstock, Honggang Yi, Hosea H Harvey, Pengcheng Xun
OBJECTIVES: To examine the trends of new and recurrent sports-related concussions in high-school athletes before and after youth sports traumatic brain injury laws. METHODS: We used an interrupted time-series design and analyzed the concussion data (2005-2016) from High School Reporting Injury Online. We examined the trends of new or recurrent concussion rates among US representative high-school athletes participating in 9 sports across prelaw, immediate-postlaw, and postlaw periods by using general linear models...
October 19, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29048965/the-effectiveness-of-hiv-prevention-interventions-in-socioeconomically-disadvantaged-ethnic-minority-women-a-systematic-review-and-meta-analysis
#19
Isabel Ruiz-Perez, Matthew Murphy, Guadalupe Pastor-Moreno, Antonio Rojas-García, Miguel Rodríguez-Barranco
BACKGROUND: Surveys in the United States and Europe have shown a plateau of new HIV cases, with certain regions and populations disproportionately affected by the disease. Ethnic minority women and socioeconomically disadvantaged groups are disproportionately affected by HIV. Previous reviews have focused on prevention interventions targeting ethnic minority men who have sex with men, have not accounted for socioeconomic status, or have included only interventions carried out in clinical settings...
October 19, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29048962/integrating-hiv-surveillance-and-field-services-data-quality-and-care-continuum-in-king-county-washington-2010-2015
#20
Julia E Hood, David A Katz, Amy B Bennett, Susan E Buskin, Julia C Dombrowski, Stephen E Hawes, Matthew R Golden
OBJECTIVES: To assess how integration of HIV surveillance and field services might influence surveillance data and linkage to care metrics. METHODS: We used HIV surveillance and field services data from King County, Washington, to assess potential impact of misclassification of prior diagnoses on numbers of new diagnoses. The relationship between partner services and linkage to care was evaluated with multivariable log-binomial regression models. RESULTS: Of the 2842 people who entered the King County HIV Surveillance System in 2010 to 2015, 52% were newly diagnosed, 41% had a confirmed prior diagnosis in another state, and 7% had an unconfirmed prior diagnosis...
October 19, 2017: American Journal of Public Health
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