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Quercetin glycoside

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https://www.readbyqxmd.com/read/28792065/environmental-plasticity-of-pinot-noir-grapevine-leaves-a-trans-european-study-of-morphological-and-biochemical-changes-along-a-1500-km-latitudinal-climatic-gradient
#1
Antonella Castagna, Kristóf Csepregi, Susanne Neugart, Gaetano Zipoli, Kristýna Večeřová, Gábor Jakab, Tjaša Jug, Laura Llorens, Javier Martínez-Abaigar, Johann Martínez-Lüscher, Encarnación Núñez-Olivera, Annamaria Ranieri, Katharina Schoedl-Hummel, Monika Schreiner, Péter Teszlák, Susanne Tittmann, Otmar Urban, Dolors Verdaguer, Marcel A K Jansen, Éva Hideg
A two-year study explored metabolic and phenotypic plasticity of sun acclimated Vitis vinifera cv. Pinot noir leaves collected from twelve locations across a 36.69(o) N - 49.98(o) N latitudinal gradient. Leaf morphological and biochemical parameters were analysed in the context of meteorological parameters and the latitudinal gradient. We found that leaf fresh weight and area were negatively correlated with both global and UV radiation; cumulated global radiation being a stronger correlator. Cumulative UV radiation (sumUVR) was the strongest correlator with most leaf metabolites and pigments...
August 9, 2017: Plant, Cell & Environment
https://www.readbyqxmd.com/read/28790397/antioxidant-activity-of-quercetin-and-its-glucosides-from-propolis-a-theoretical-study
#2
Yan-Zhen Zheng, Geng Deng, Qin Liang, Da-Fu Chen, Rui Guo, Rong-Cai Lai
Among the multiple components of propolis, flavonoids contribute greatly to the antioxidant activities of propolis. Flavonoids mainly exist in the form of sugar-conjugated derivatives. Quercetin glycosides represent the predominant flavonoid fraction in propolis. In this work, density functional theory (DFT) calculations were applied to analyze the antioxidative properties of quercetin and its glucosides in the gas and in the liquid phase (ethanol, water). Three main antioxidant mechanisms, hydrogen atom transfer (HAT), single electron transfer followed by proton transfer (SET-PT) and sequential proton loss electron transfer (SPLET) were used to analyze the antioxidative capacity of the investigated compounds...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28767066/isorhamnetin-and-quercetin-derivatives-as-anti-acetylcholinesterase-principles-of-marigold-calendula-officinalis-flowers-and-preparations
#3
Daniil N Olennikov, Nina I Kashchenko, Nadezhda K Chirikova, Anzurat Akobirshoeva, Ifrat N Zilfikarov, Cecile Vennos
Marigold (Calendula officinalis L.) is one of the most common and widespread plants used medicinally all over the world. The present study aimed to evaluate the anti-acetylcholinesterase activity of marigold flowers, detect the compounds responsible and perform chemical analysis of marigold commercial products. Analysis of 23 varieties of C. officinalis flowers introduced into Siberia allowed us to select the Greenheart Orange variety due to the superior content of flavonoids (46.87 mg/g) and the highest inhibitory activity against acetylcholinesterase (IC50 63...
August 2, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28766621/detailed-phytochemical-characterization-and-bioactive-properties-of-myrtus-nivelii-batt-trab
#4
Wahiba Rached, Malika Bennaceur, Lillian Barros, Ricardo C Calhelha, Sandrina Heleno, Maria José Alves, Ana Maria Carvalho, Abderrazak Marouf, Isabel C F R Ferreira
The endemic Algerian myrtle, Myrtus nivelii Batt & Trab., was evaluated for its bioactive properties, such as antioxidant, anti-inflammatory, cytotoxic and antibacterial activities, and correlated with the individual phenolic compounds identified in its crude aqueous extract and subsequent organic fractions (ethyl acetate and butanol). Flavonols, such as myricetin, kaempferol and quercetin glycoside derivatives, were the major phenolic compounds found, along with the presence of ellagitannins. The ethyl acetate fraction contained the highest amount of phenolic compounds, followed by the butanol fraction and, finally, the crude aqueous extract...
August 2, 2017: Food & Function
https://www.readbyqxmd.com/read/28766086/anti-inflammatory-evaluation-and-characterization-of-leaf-extract-of-ananas-comosus
#5
Samira Kargutkar, S Brijesh
Ananas comosus (L.) Merr (Pineapple) is a tropical plant with an edible fruit. In the present study, the potential anti-inflammatory activity of A. comosus leaf extract (ALE) was studied. ALE prepared using soxhlet apparatus was subjected to preliminary qualitative phytochemical analysis and quantitative estimations of flavonoids and tannins. The components present in ALE were identified using liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS). Inhibitory effects of ALE on protein denaturation, and proteinase activity were assessed...
August 1, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/28752532/rutin-a-quercetin-glycoside-restores-chemosensitivity-in-human-breast-cancer-cells
#6
Marcello Iriti, Robert Kubina, Andrea Cochis, Rita Sorrentino, Elena M Varoni, Agata Kabała-Dzik, Barbara Azzimonti, Arkadiusz Dziedzic, Lia Rimondini, Robert D Wojtyczka
Several studies have documented the ability of flavonoids to sensitize cancer cells to chemotherapeutics and reverse multidrug resistance by inhibition of efflux pumps (adenosine triphosphate-binding cassette transporters), apoptosis activation, and cell cycle arrest. In this study, the flavonoid rutin (quercetin 3-O-β-d-rutinoside) was investigated as chemosensitizer towards two different human epithelial breast cancer cell lines: (i) MB-MDA-231, selected as representative for triple-negative breast cancer and (ii) MCF-7 used as a well-characterized model of HER2-negative breast cancer...
July 28, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28720959/fortification-of-the-whey-protein-isolate-antioxidant-and-antidiabetic-activity-with-fraction-rich-in-phenolic-compounds-obtained-from-stevia-rebaudiana-bert-bertoni-leaves
#7
Paula Gimenez Milani, Maysa Formigoni, Yago Carvalho Lima, Silvano Piovan, Giuliana Maria Ledesma Peixoto, Daiane Montoia Camparsi, Willian do Nascimento da Silva Rodrigues, Jordana Quaglia Pereira da Silva, Alexandre da Silva Avincola, Eduardo Jorge Pilau, Cecília Edna Mareze da Costa, Silvio Cláudio da Costa
A stevia fraction (ASF) free of steviol glycosides was extracted from Stevia rebaudiana leaves (Stevia UEM-13). ASF essentially constitutes phenolic compounds (52.42%), which were identified by liquid chromatography tandem mass spectrometry (LC-MS/MS) as caffeic acid, quercetin-3-o-glycoside, cyanidin-3-glucoside, kaempferol, quercetin, apigenin, rozmarinic acid, chlorogenic acid and dicaffeoylquinic acid. ASF was used as a multi-functional source of phenolic compounds to fortify the whey protein isolate (WPI) obtained by membrane separation...
June 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28716425/characterization-and-quantification-of-flavonoids-and-organic-acids-over-fruit-development-in-american-cranberry-vaccinium-macrocarpon-cultivars-using-hplc-and-apci-ms-ms
#8
Yifei Wang, Jennifer Johnson-Cicalese, Ajay P Singh, Nicholi Vorsa
Cranberry flavonoids, including anthocyanins, flavonol glycosides and proanthocyanidins, and organic acids were characterized and quantified by HPLC and LC-MS/MS during fruit development and ripening in eight cranberry cultivars. Anthocyanin biosynthesis initiated at early fruit development and reached highest level in mature fruit, with significant differences between cultivars. Major flavonol glycosides, including the most abundant quercetin-3-galactoside and myricetin-3-galactoside, showed consistent concentrations during the season with moderate fluctuation, and were at similar levels in mature fruits of the eight cultivars...
September 2017: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/28707708/identification-and-quantification-of-phenolic-compounds-in-edible-wild-leafy-vegetables-by-uhplc-orbitrap-ms
#9
Elisa Giambanelli, L Filippo D'Antuono, Roberto Romero-González, Antonia Garrido Frenich
BACKGROUND: A recent interest in edible wild leafy vegetables has been documented. Consumers often associate these species to health promotion. In this study several wild species of the Asteraceae family and Knautia integrifolia (Dipsacaceae) were locally documented for their use in traditional cuisine and sampled from the wild. RESULTS: Phenolic compounds were identified and quantified by ultra-high-performance liquid chromatography coupled to Orbitrap high resolution mass spectrometry...
July 14, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28688956/flavonoid-glycosides-from-barringtonia-acutangula
#10
Le Thi Vien, Quach Thi Thanh Van, Tran Thi Hong Hanh, Phan Thi Thanh Huong, Nguyen Thi Kim Thuy, Nguyen The Cuong, Nguyen Hai Dang, Nguyen Van Thanh, Nguyen Xuan Cuong, Nguyen Hoai Nam, Phan Van Kiem, Chau Van Minh
Using various chromatographic separation techniques, ten flavonoid glycosides, including six new compounds namely barringosides A-F (1-6), were isolated from a methanol extract of the Barringtonia acutangula leaves. The structure elucidation was confirmed by spectroscopic analyses, including 1D and 2D NMR, and HR ESI MS. Their inhibitory effects on LPS-induced NO production in RAW264.7 cells were also evaluated. Among the isolated compounds, quercetin 3-O-β-d-(6-p-hydroxybenzoyl)galactopyranoside (9) showed significant effect with an IC50 of 20...
June 27, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28667870/anti-radical-flavonol-glycosides-from-the-aerial-parts-of-cleome-chelidonii-l-f
#11
Phuc-Dam Nguyen, Charlotte Sayagh, Nicolas Borie, Catherine Lavaud
Eleven previously undescribed flavonoid glycosides, named cleomesides C-M, along with five known compounds, were isolated from the aerial parts of Cleome chelidonii L.f. (Cleomaceae). All flavonol glycosides were esterified derivatives of 3,7-O-diglycosides of quercetin or kaempferol. Their structures were elucidated by analysis of the 1D and 2D NMR spectra, HR-ESI-MS data, UV spectra, optical rotation and by comparison with literature data. The DPPH radical scavenging properties of the flavonoid glycosides were studied in order to appreciate the effect of the glycoside parts and of the ester groups on this activity compared with the quercetin and kaempferol aglycones...
June 28, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28633497/genome-wide-identification-and-functional-characterization-of-udp-glucosyltransferase-genes-involved-in-flavonoid-biosynthesis-in-glycine-max
#12
Qinggang Yin, Guoan Shen, Shaokang Di, Cunying Fan, Zhenzhan Chang, Yongzhen Pang
Flavonoids, natural products abundant in the model legume Glycine max, confer benefits to plants and animals health. Flavonoids are present in soybean mainly as glycoconjugates. However, the biosynthesis mechanisms of flavonoid glycosides are largely unknown in G. max. In the present study, 212 putative UDP-glycosyltransferase (UGTs) genes were identified in G. max by genome-wide searching. The GmUGT genes were distributed differentially among the twenty chromosomes, and they were expressed in various tissues with distinct expression profile...
June 19, 2017: Plant & Cell Physiology
https://www.readbyqxmd.com/read/28623737/rumpictuside-a-unusual-9-10-anthraquinone-glucoside-from-rumex-pictus-forssk
#13
Walaa A El-Kashak, Abdelsamed I Elshamy, Tarik A Mohamed, Abd El-Nasser G El Gendy, Ibrahim A Saleh, Akemi Umeyama
A new 8-ionized hydroxylated 9,10-anthraquinone namely, 1-hydroxy-3-methyl-9,10-anthraquinone-6-O-β-D-glucopyranoside-8-olate (Rumpictuside A, 1) along with five known flavonoids, apigenin 7-O-β-D-glucoside (2), vitexin (3), quercetin 3-O-β-D-glucouronide (4), orientin (5), and isorientin (6) were isolated from Rumex pictus. The structures of isolated compounds were identified by the extensive spectroscopic techniques such as, UV, FT-IR, 1D, 2D NMR and HR-FAB-ESI-MS. The ionized hydroxyl group in the new anthraquinone (1) was rarely found for anthraquinone glycosides isolated from natural sources...
June 9, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/28597993/one-step-extraction-and-hydrolysis-of-flavonoid-glycosides-in-rape-bee-pollen-based-on-soxhlet-assisted-matrix-solid-phase-dispersion
#14
Xijuan Tu, Shuangqin Ma, Zhaosheng Gao, Jing Wang, Shaokang Huang, Wenbin Chen
INTRODUCTION: Flavonoids are frequently found as glycosylated derivatives in plant materials. To determine contents of flavonoid aglycones in these matrices, procedures for the extraction and hydrolysis of flavonoid glycosides are required. The current sample preparation method is both labour and time consuming. OBJECTIVE: Develop a modified matrix solid phase dispersion (MSPD) procedure as an alternative methodology for the one-step extraction and hydrolysis of flavonoid glycosides...
June 9, 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/28572959/bioactive-phytochemicals-in-an-aqueous-extract-of-the-leaves-of-talinum-triangulare
#15
Catherine C Ikewuchi, Jude C Ikewuchi, Mercy O Ifeanacho
An aqueous leaf extract of Talinum triangulare was screened for the presence of bioactive molecules, using gas chromatography coupled with pulse and flame ionization detectors. It had high carotenoids; moderate benzoic acid derivatives, hydroxycinnamates and flavonoids; and low terpenes, alkaloids, phytosterols, allicins, glycosides, saponins, and lignans contents. Ten known carotenoids (mainly 50.42% carotene and 33.30% lycopene), nine benzoic acid derivatives (mainly 84.63% ferulic acid and 11.92% vanillic acid), and six hydroxycinnamates (55...
May 2017: Food Science & Nutrition
https://www.readbyqxmd.com/read/28569164/omega-3-fatty-acids-phenolic-compounds-and-antioxidant-characteristics-of-chia-oil-supplemented-margarine
#16
Muhammad Nadeem, Muhammad Imran, Imran Taj, Muhammad Ajmal, Muhammad Junaid
BACKGROUND: Chia (Salvia hispanica L.) is known as power house of omega fatty acids which has great health benefits. It contains up to 78% linolenic acid (ω-3) and 18% linoleic acid (ω-6), which could be a great source of omega-3 fatty acids for functional foods. Therefore, in this study, margarines were prepared with supplementation of different concentrations of chia oil to enhance omega-3 fatty acids, antioxidant characteristics and oxidative stability of the product. METHODS: Margarines were formulated from non-hydrogenated palm oil, palm kernel and butter...
May 31, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28561159/new-constituents-from-gymnocarpos-decander
#17
Houria Bechlem, Teresa Mencherini, Mohamed Bouheroum, Samir Benayache, Roberta Cotugno, Alessandra Braca, Nunziatina De Tommasi
The phytochemical investigation of Gymnocarpos decander aerial parts extract afforded two new saponins, 3-O-β-D-glucuronopyranosyl-2β,3β,16α,23-tetrahydroxyolean-12-en-28-O-β-D-apiofuranosyl-(1 → 3)-β-D-xylopyranosyl-(1 → 4)-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranosyl ester (1), 3-O-β-D-glucuronopyranosyl-2β,3β,16α-trihydroxyolean-12-en-28-O-α-L-rhamnopyranosyl-(1 → 3)-β-D-xylopyranosyl-(1 → 4)-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranosyl ester (2), and three new flavonol glycosides, isorhamnetin 3-O-2''''-O-acetyl-β-D-xylopyranosyl-(1 → 6)-[β-D-apiofuranosyl-(1 → 2)]-β-D-glucopyranoside (3), isorhamnetin 3-O-2‴-O-acetyl-β-D-xylopyranosyl-(1 → 6)-β-D-glucopyranoside (4), and quercetin 3-O-2‴-O-acetyl-β-D-xylopyranosyl-(1 → 6)-β-D-glucopyranoside (5), together with three known compounds...
May 29, 2017: Planta Medica
https://www.readbyqxmd.com/read/28558824/the-cruciferous-diplotaxis-simplex-phytochemistry-analysis-and-its-protective-effect-on-liver-and-kidney-toxicities-and-lipid-profile-disorders-in-alloxan-induced-diabetic-rats
#18
Hamida Jdir, Rihab Ben Abdallah Kolsi, Sami Zouari, Khaled Hamden, Nacim Zouari, Nahed Fakhfakh
BACKGROUND: Type 2 diabetes mellitus is a prevalent systemic disease affecting an important proportion of the population worldwide. It has been suggested that excessive reactive oxygen species generation and therefore development of an oxidative stress status is a key factor leading to diabetic complications. Accordingly, it seems that medicinal plants can offer a wide range of new antidiabetic drugs. Diplotaxis simplex (Viv.) Spreng. (Brassicaceae) is an edible plant largely distributed in the Mediterranean region...
May 30, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28554615/utilization-of-quercetin-and-quercetin-glycosides-from-onion-allium-cepa-l-solid-waste-as-an-antioxidant-urease-and-xanthine-oxidase-inhibitors
#19
Shivraj Hariram Nile, Arti Shivraj Nile, Young Soo Keum, Kavita Sharma
This study aimed to determine the flavonol glycosides from onion solid waste (OSW) using HPLC analysis, with antioxidant and enzyme inhibitory activities. We found considerable amount of quercetin-4'-O-monoglucoside (QMG: 254.85), quercetin-3,4'-O-diglucoside (QDG: 162.34), quercetin (Q: 60.44), and isorhamnetin-3-glucoside (IMG: 23.92) (mg/100g) dry weight (DW) of OSW. For OSW, the methanol and ethanol showed the strongest antioxidant activities, followed by ethyl acetate, chloroform, and n-hexane extracts...
November 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28550653/phytochemical-profile-and-angiotensin-i-converting-enzyme-ace-inhibitory-activity-of-limonium-michelsonii-lincz
#20
Janar Jenis, Jeong Yoon Kim, Zia Uddin, Yeong Hun Song, Hyeong-Hwan Lee, Ki Hun Park
Members of the genus Limonium are widely used as medicinal herbs due to their health-promoting effects, such as an ability to improve blood circulation by inhibiting angiotensin I converting enzyme (ACE). While the potential of L. michelsonii Lincz. (a medicinal plant endemic to Kazakhstan) to inhibit ACE has been demonstrated, the inhibitory activities of its secondary metabolites have not been explored. In this work, the principal phenolic compounds (1-20) among these metabolites were isolated to determine the components responsible for ACE inhibition...
May 26, 2017: Journal of Natural Medicines
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