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Quercetin glycoside

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https://www.readbyqxmd.com/read/28911741/growth-hydrolases-and-ultrastructure-of-fusarium-oxysporum-as-affected-by-phenolic-rich-extracts-from-several-xerophytic-plants
#1
Mahmoud S M Mohamed, Ahmed M Saleh, Ibrahim B Abdel-Farid, Sabry A El-Naggar
Fusarium oxysporum, the causal agent of rot and wilt diseases, is one of the most detrimental phytopathogens for the productivity of many economic crops. The present study was conducted to evaluate the potentiality of some xerophytic plants as eco-friendly approach for management of F. oxysporum. Phenolic rich extracts from five plants namely: Horwoodia dicksoniae, Citrullus colocynthis, Gypsophila capillaris, Pulicaria incisa and Rhanterium epapposum were examined in vitro. The different extracts showed high variability in their phenolic and flavonoid contents as well as total antioxidant capacity...
September 2017: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/28894456/effects-of-combined-low-glutathione-with-mild-oxidative-and-low-phosphorus-stress-on-the-metabolism-of-arabidopsis-thaliana
#2
Atsushi Fukushima, Mami Iwasa, Ryo Nakabayashi, Makoto Kobayashi, Tomoko Nishizawa, Yozo Okazaki, Kazuki Saito, Miyako Kusano
Plants possess highly sensitive mechanisms that monitor environmental stress levels for a dose-dependent fine-tuning of their growth and development. Differences in plant responses to severe and mild abiotic stresses have been recognized. Although many studies have revealed that glutathione can contribute to plant tolerance to various environmental stresses, little is known about the relationship between glutathione and mild abiotic stress, especially the effect of stress-induced altered glutathione levels on the metabolism...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28891998/bioactivity-in-vitro-of-quercetin-glycoside-obtained-in-beauveria-bassiana-culture-and-its-interaction-with-liposome-membranes
#3
Paulina Strugała, Tomasz Tronina, Ewa Huszcza, Janina Gabrielska
Quercetin (Q) was used as substrate for regioselective glycosylation at the C-7 position catalyzed by Beauveria bassiana AM278 strain. As a result the glycoside quercetin 7-O-β-d-(4″-O-methyl)glucopyranoside (Q 7-MeGlu) was formed. The goal of the studies was to determine the anti-oxidative (liposome membrane protection against free radicals IC50(Q 7-MeGlu) = 5.47 and IC50(Q) = 4.49 µM) and anti-inflammatory (COX-1 and COX-2 enzymes activity inhibition) properties of Q 7-MeGlu as compared to Q. Every attempt was made to clarify the antioxidant activity of these molecules, which are able to interact with egg phosphatidylcholine liposomes, using a fluorometric method (by applying the probes MC540, TMA-DPH and DPH)...
September 11, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28876399/new-seminal-variety-of-stevia-rebaudiana-obtaining-fractions-with-high-antioxidant-potential-of-leaves
#4
Paula G Milani, Maysa Formigoni, Antonio S Dacome, Livia Benossi, Cecília E M DA Costa, Silvio C DA Costa
The aim of this study was to determine the composition and antioxidant potential of leaves of a new variety of Stevia rebaudiana (Stevia UEM-13). Stevia leaves of UEM-13 contain rebaudioside A as the main glycoside, while most wild Stevia plants contain stevioside. Furthermore can be multiplied by seed, which reduces the cost of plant culture techniques as other clonal varieties are multiplied by buds, requiring sophisticated and expensive seedling production systems. Ethanol and methanol were used in the extraction to determine the bioactive compounds...
August 31, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28873762/the-novel-contributors-of-anti-diabetic-potential-in-mulberry-polyphenols-revealed-by-uhplc-hr-esi-tof-ms-ms
#5
Fuhua Li, Bin Zhang, Gu Chen, Xiong Fu
To explore the comprehensive phenolic profile of mulberry (Morus alba L.) fruit and reveal the novel anti-diabetic constituents, mulberry polyphenols (MP) were fractionated through gradient ethanol elution and subjected to composition and bioactivity analysis. Forty-seven phenolic compounds were identified and quantified through UHPLC-HR-ESI-TOF-MS/MS, including twenty-one newly identified compounds such as delphinidin 3-rutinoside-5-glucoside and cyanidin 3-rutinoside dimer. The antioxidant activity and anti-diabetic potential of fractionated MP were analyzed in vitro and ex vivo with HepG2 and pancreatic β-cell RIN-m5F...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28873690/nutritional-compound-analysis-and-morphological-characterization-of-spider-plant-cleome-gynandra-an-african-indigenous-leafy-vegetable
#6
Emmanuel O Omondi, Christof Engels, Godfrey Nambafu, Monika Schreiner, Susanne Neugart, Mary Abukutsa-Onyango, Traud Winkelmann
Spider plant is among the important indigenous African leafy vegetables having the potential to contribute to food and nutritional security in sub-Saharan Africa. The main objective of this study was to quantify the mineral concentration, to identify and quantify glucosinolates and flavonoids in spider plant and further to characterize spider plant entries using important morphological traits. Thirty spider plant entries from different African countries, comprising of farmers' cultivars, gene bank accessions and advanced lines were grown in a field experiment and harvested for leaves, stems, flowers and siliques at different developmental stages...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28872626/anti-melanogenic-effects-of-flavonoid-glycosides-from-limonium-tetragonum-thunb-bullock-via-inhibition-of-tyrosinase-and-tyrosinase-related-proteins
#7
Seul-Gi Lee, Fatih Karadeniz, Youngwan Seo, Chang-Suk Kong
Overproduction and stimulation of tyrosinase result in increased melanogenesis of which several skin disorders such as freckles, spots, and hyperpigmentation appear as complications. Limonium tetragonum is a halophyte well-known for its antioxidative properties. This study investigated the anti-melanogenic effects of solvent-partitioned L. tetragonum extracts (LTEs) and its bioactive constituents, two isolated flavonoid glycosides. Current study followed a set of experiments on B16-F10 mouse melanoma cell model with a focus on tyrosinase activity and production...
September 5, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28857481/fingerprint-profiles-of-flavonoid-compounds-from-different-psidium-guajava-leaves-and-their-antioxidant-activities
#8
Lu Wang, Yanan Wu, Qi Bei, Kan Shi, Zhenqiang Wu
Flavonoids are the main active components in Psidium guajava leaves and have many multi-physiological functions. In this study, the flavonoid compositions were identified in the Psidium guajava leaves samples using a high-performance liquid chromatography with time-of-flight electrospray ionization mass spectrometry method. A high-performance liquid chromatography fingerprint method, combined with chemometrics, was used to perform a quality assessment of the Psidium guajava leaves samples. The eight identified flavonoid compounds including rutin, isoquercitrin, quercetin-3-O-β-d-xylopyranoside, quercetin-3-O-α-l-arabinopyranoside, avicularin, quercitrin, quercetin, and kaempferol were used as the chemical markers...
August 31, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28855836/variation-of-quercetin-glycoside-derivatives-in-three-onion-allium-cepa-l-varieties
#9
Jung-Ho Kwak, Jeong Min Seo, Na-Hyung Kim, Mariadhas Valan Arasu, Sunggil Kim, Moo Kyoung Yoon, Sun-Ju Kim
The aim of this study was to quantify the contents of individual quercetin glycosides in red, yellow and chartreuse onion by High Performance Liquid Chromatography (HPLC) analysis. Acid hydrolysis of individual quercetin glycosides using 6 M hydrochloric acid guided to identify and separate quercetin 7,4'-diglucoside, quercetin 3-glucoside, quercetin 4'-glucoside, and quercetin. The contents of total quercetin glycosides varied extensively among three varieties (ranged from 16.10 to 103.93 mg/g DW). Quercetin was the predominant compound that accounted mean 32...
September 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28839374/hepatoprotective-flavonoids-in-opuntia-ficus-indica-fruits-by-reducing-oxidative-stress-in-primary-rat-hepatocytes
#10
Jung Wha Kim, Tae Bum Kim, Hyun Woo Kim, Sang Wook Park, Hong Pyo Kim, Sang Hyun Sung
BACKGROUND: Liver disorder was associated with alcohol consumption caused by hepatic cellular damages. Opuntia ficus-indica fruit extracts (OFIEs), which contain betalain pigments and polyphenols including flavonoids, have been introduced as reducing hangover symptoms and liver protective activity. OBJECTIVE: To evaluate hepatoprotective activity of OFIEs and isolated compounds by high-speed countercurrent chromatography (HSCCC). MATERIALS AND METHODS: The extract of O...
July 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28836990/wound-healing-effect-of-euphorbia-hirta-linn-euphorbiaceae-in-alloxan-induced-diabetic-rats
#11
Riazul Haque Tuhin, Marium Begum, Sohanur Rahman, Rubaba Karim, Taslima Begum, Siraj Uddin Ahmed, Ronia Mostofa, Amir Hossain, Mohamed Abdel-Daim, Rayhana Begum
BACKGROUND: Euphorbia hirta linn., is a species of Euphorbiaceae family. They are known as asthma plant, barokhervi. The plant E. hirta is famous for its medicinal importance among the tribal population. It is a common practice to use the whole to heal wounds. Several pharmacological properties including antiseptic, anti-inflammatory, antidibetic, antispasmodic, antibacterial, antiviral, antifungal, anticonvulsant, nootropic, antifertility and aphrodisiac properties have already been reported for this plant...
August 24, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28828965/3-4-dihydroxyphenylacetic-acid-is-a-potential-aldehyde-dehydrogenase-inducer-in-murine-hepatoma-hepa1c1c7-cells
#12
Yujia Liu, Ayuki Kurita, Sayaka Nakashima, Beiwei Zhu, Shintaro Munemasa, Toshiyuki Nakamura, Yoshiyuki Murata, Yoshimasa Nakamura
3,4-Dihydroxyphenylacetic acid (DOPAC) is one of the major colonic microflora-produced catabolites of quercetin glycosides, such as quercetin 4'-glucoside derived from onion. Here, we investigated whether DOPAC modulates the aldehyde dehydrogenase (ALDH) activity and protects the cells from the acetaldehyde-induced cytotoxicity in vitro. DOPAC was shown to enhance not only the total ALDH activity, but also the gene expression of ALDH1A1, ALDH2 and ALDH3A1 in a concentration-dependent manner. DOPAC simultaneously stimulated the nuclear translocation of NFE2-related factor 2 and aryl hydrocarbon receptor...
August 22, 2017: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/28792065/environmental-plasticity-of-pinot-noir-grapevine-leaves-a-trans-european-study-of-morphological-and-biochemical-changes-along-a-1500-km-latitudinal-climatic-gradient
#13
Antonella Castagna, Kristóf Csepregi, Susanne Neugart, Gaetano Zipoli, Kristýna Večeřová, Gábor Jakab, Tjaša Jug, Laura Llorens, Javier Martínez-Abaigar, Johann Martínez-Lüscher, Encarnación Núñez-Olivera, Annamaria Ranieri, Katharina Schoedl-Hummel, Monika Schreiner, Péter Teszlák, Susanne Tittmann, Otmar Urban, Dolors Verdaguer, Marcel A K Jansen, Éva Hideg
A two-year study explored metabolic and phenotypic plasticity of sun acclimated Vitis vinifera cv. Pinot noir leaves collected from twelve locations across a 36.69(o) N - 49.98(o) N latitudinal gradient. Leaf morphological and biochemical parameters were analysed in the context of meteorological parameters and the latitudinal gradient. We found that leaf fresh weight and area were negatively correlated with both global and UV radiation; cumulated global radiation being a stronger correlator. Cumulative UV radiation (sumUVR) was the strongest correlator with most leaf metabolites and pigments...
August 9, 2017: Plant, Cell & Environment
https://www.readbyqxmd.com/read/28790397/antioxidant-activity-of-quercetin-and-its-glucosides-from-propolis-a-theoretical-study
#14
Yan-Zhen Zheng, Geng Deng, Qin Liang, Da-Fu Chen, Rui Guo, Rong-Cai Lai
Among the multiple components of propolis, flavonoids contribute greatly to the antioxidant activities of propolis. Flavonoids mainly exist in the form of sugar-conjugated derivatives. Quercetin glycosides represent the predominant flavonoid fraction in propolis. In this work, density functional theory (DFT) calculations were applied to analyze the antioxidative properties of quercetin and its glucosides in the gas and in the liquid phase (ethanol, water). Three main antioxidant mechanisms, hydrogen atom transfer (HAT), single electron transfer followed by proton transfer (SET-PT) and sequential proton loss electron transfer (SPLET) were used to analyze the antioxidative capacity of the investigated compounds...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28767066/isorhamnetin-and-quercetin-derivatives-as-anti-acetylcholinesterase-principles-of-marigold-calendula-officinalis-flowers-and-preparations
#15
Daniil N Olennikov, Nina I Kashchenko, Nadezhda K Chirikova, Anzurat Akobirshoeva, Ifrat N Zilfikarov, Cecile Vennos
Marigold (Calendula officinalis L.) is one of the most common and widespread plants used medicinally all over the world. The present study aimed to evaluate the anti-acetylcholinesterase activity of marigold flowers, detect the compounds responsible and perform chemical analysis of marigold commercial products. Analysis of 23 varieties of C. officinalis flowers introduced into Siberia allowed us to select the Greenheart Orange variety due to the superior content of flavonoids (46.87 mg/g) and the highest inhibitory activity against acetylcholinesterase (IC50 63...
August 2, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28766621/detailed-phytochemical-characterization-and-bioactive-properties-of-myrtus-nivelii-batt-trab
#16
Wahiba Rached, Malika Bennaceur, Lillian Barros, Ricardo C Calhelha, Sandrina Heleno, Maria José Alves, Ana Maria Carvalho, Abderrazak Marouf, Isabel C F R Ferreira
The endemic Algerian myrtle, Myrtus nivelii Batt & Trab., was evaluated for its bioactive properties, such as antioxidant, anti-inflammatory, cytotoxic and antibacterial activities, and correlated with the individual phenolic compounds identified in its crude aqueous extract and subsequent organic fractions (ethyl acetate and butanol). Flavonols, such as myricetin, kaempferol and quercetin glycoside derivatives, were the major phenolic compounds found, along with the presence of ellagitannins. The ethyl acetate fraction contained the highest amount of phenolic compounds, followed by the butanol fraction and, finally, the crude aqueous extract...
August 2, 2017: Food & Function
https://www.readbyqxmd.com/read/28766086/anti-inflammatory-evaluation-and-characterization-of-leaf-extract-of-ananas-comosus
#17
Samira Kargutkar, S Brijesh
Ananas comosus (L.) Merr (Pineapple) is a tropical plant with an edible fruit. In the present study, the potential anti-inflammatory activity of A. comosus leaf extract (ALE) was studied. ALE prepared using soxhlet apparatus was subjected to preliminary qualitative phytochemical analysis and quantitative estimations of flavonoids and tannins. The components present in ALE were identified using liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-mass spectrometry (GC-MS). Inhibitory effects of ALE on protein denaturation, and proteinase activity were assessed...
August 1, 2017: Inflammopharmacology
https://www.readbyqxmd.com/read/28752532/rutin-a-quercetin-glycoside-restores-chemosensitivity-in-human-breast-cancer-cells
#18
Marcello Iriti, Robert Kubina, Andrea Cochis, Rita Sorrentino, Elena M Varoni, Agata Kabała-Dzik, Barbara Azzimonti, Arkadiusz Dziedzic, Lia Rimondini, Robert D Wojtyczka
Several studies have documented the ability of flavonoids to sensitize cancer cells to chemotherapeutics and reverse multidrug resistance by inhibition of efflux pumps (adenosine triphosphate-binding cassette transporters), apoptosis activation, and cell cycle arrest. In this study, the flavonoid rutin (quercetin 3-O-β-d-rutinoside) was investigated as chemosensitizer towards two different human epithelial breast cancer cell lines: (i) MB-MDA-231, selected as representative for triple-negative breast cancer and (ii) MCF-7 used as a well-characterized model of HER2-negative breast cancer...
July 28, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28720959/fortification-of-the-whey-protein-isolate-antioxidant-and-antidiabetic-activity-with-fraction-rich-in-phenolic-compounds-obtained-from-stevia-rebaudiana-bert-bertoni-leaves
#19
Paula Gimenez Milani, Maysa Formigoni, Yago Carvalho Lima, Silvano Piovan, Giuliana Maria Ledesma Peixoto, Daiane Montoia Camparsi, Willian do Nascimento da Silva Rodrigues, Jordana Quaglia Pereira da Silva, Alexandre da Silva Avincola, Eduardo Jorge Pilau, Cecília Edna Mareze da Costa, Silvio Cláudio da Costa
A stevia fraction (ASF) free of steviol glycosides was extracted from Stevia rebaudiana leaves (Stevia UEM-13). ASF essentially constitutes phenolic compounds (52.42%), which were identified by liquid chromatography tandem mass spectrometry (LC-MS/MS) as caffeic acid, quercetin-3-o-glycoside, cyanidin-3-glucoside, kaempferol, quercetin, apigenin, rozmarinic acid, chlorogenic acid and dicaffeoylquinic acid. ASF was used as a multi-functional source of phenolic compounds to fortify the whey protein isolate (WPI) obtained by membrane separation...
June 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28716425/characterization-and-quantification-of-flavonoids-and-organic-acids-over-fruit-development-in-american-cranberry-vaccinium-macrocarpon-cultivars-using-hplc-and-apci-ms-ms
#20
Yifei Wang, Jennifer Johnson-Cicalese, Ajay P Singh, Nicholi Vorsa
Cranberry flavonoids, including anthocyanins, flavonol glycosides and proanthocyanidins, and organic acids were characterized and quantified by HPLC and LC-MS/MS during fruit development and ripening in eight cranberry cultivars. Anthocyanin biosynthesis initiated at early fruit development and reached highest level in mature fruit, with significant differences between cultivars. Major flavonol glycosides, including the most abundant quercetin-3-galactoside and myricetin-3-galactoside, showed consistent concentrations during the season with moderate fluctuation, and were at similar levels in mature fruits of the eight cultivars...
September 2017: Plant Science: An International Journal of Experimental Plant Biology
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