keyword
MENU ▼
Read by QxMD icon Read
search

Quercetin glycoside

keyword
https://www.readbyqxmd.com/read/28513167/quercetin-luteolin-phloretin-and-morin-are-dietary-flavonoid-inhibitors-of-monocarboxylate-transporter-6
#1
Robert Spencer Jones, Mark Parker, Marilyn Emily Morris
Monocarboxylate transporter 6 (MCT6; SLC16A5) has been recognized for its role as a xenobiotic transporter, with characterized substrates probenecid, bumetanide, and nateglinide. To date, the impact of commonly ingested dietary compounds on MCT6 function has not been investigated and therefore, the objective of this study was to evaluate a variety of flavonoids for their potential MCT6-specific interactions. Flavonoids are a large group of polyphenolic phytochemicals found in commonly consumed plant-based products that have been recognized for their dietary health benefits...
May 17, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28512639/inhibitory-effect-of-chemical-constituents-isolated-from-artemisia-iwayomogi-on-polyol-pathway-and-simultaneous-quantification-of-major-bioactive-compounds
#2
Yoon Kyoung Lee, Eun Young Hong, Wan Kyunn Whang
Blocking the polyol pathway plays an important role preventing diabetic complications. Therefore, aldose reductase (AR) and advanced glycation endproducts (AGEs) formation has significant effect on diabetic complications. Artemisia iwayomogi has long been used as treatment of various diseases in Korea. However, no literatures have reported on AR and AGEs formation inhibitory activities of A. iwayomogi. For these reasons, we aimed to assess that A. iwayomogi had potential as anti-diabetic complications agents...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28503053/pea-pisum-sativum-and-its-anticancer-activity
#3
REVIEW
Runchana Rungruangmaitree, Wannee Jiraungkoorskul
Pisum sativum (Family: Fabaceae), as known as green pea or garden pea, has long been important in diet due to its content of fiber, protein, starch, trace elements, and many phytochemical substances. It has been shown to possess antibacterial, antidiabetic, antifungal, anti-inflammatory, antihypercholesterolemia, and antioxidant activities and also shown anticancer property. Its nonnutritive biologically active components include alkaloids, flavonoids, glycosides, isoflavones, phenols, phytosterols, phytic acid, protease inhibitors, saponins, and tannins...
January 2017: Pharmacognosy Reviews
https://www.readbyqxmd.com/read/28503048/antifertility-effect-of-bougainvillea-spectabilis-or-paper-flower
#4
REVIEW
Anisa Ghogar, Wannee Jiraungkoorskul
Bougainvillea spectabilis (Family: Nyctaginaceae), commonly referred to as Great Bougainvillea or Paper Flower, is one of the traditional medicinal plants with potential antifertility activity. The aqueous extract and decoction of this plant have been used as fertility control among the tribal people in many countries. Furthermore, it has been shown to possess anticancer, antidiabetic, antihepatotoxic, anti-inflammatory, antihyperlipidemic, antimicrobial, antioxidant, and antiulcer properties. Its phytoconstituents such as alkaloids, essential oils, flavonoids, glycosides, oxalates, phenolics, phlobotannins, quinones, saponins, tannins, and terpenoids were reported as the basis of its efficacious therapeutic properties...
January 2017: Pharmacognosy Reviews
https://www.readbyqxmd.com/read/28497036/reversed-phase-hplc-dad-profiling-of-carotenoids-chlorophylls-and-phenolic-compounds-in-adiantum-capillus-veneris-leaves
#5
Alam Zeb, Fareed Ullah
Adiantum capillus-veneris is important endangered fern species with several medicinal properties. In this study, the leaves samples were extracted and separated using reversed phase HPLC with DAD for carotenoids, chlorophylls and phenolic compounds. Separation of carotenoids and chlorophylls were carried out using a tertiary gradient system of water, MTBE and methanol-water, while a binary gradient system of methanol-water-acetic acid was used for phenolic profiling. Results revealed eight carotenoids, four pheophytins, and two chlorophylls...
2017: Frontiers in Chemistry
https://www.readbyqxmd.com/read/28494336/metabolite-profiling-of-flavonols-and-in-vitro-antioxidant-activity-of-young-shoots-of-wild-humulus-lupulus-l-hop
#6
Annalisa Maietti, Virginia Brighenti, Gianpiero Bonetti, Paola Tedeschi, Francesco Pio Prencipe, Stefania Benvenuti, Vincenzo Brandolini, Federica Pellati
Humulus lupulus L., commonly named hop, is well-known for its sedative and estrogenic activity. While hop cones are widely characterized, only few works have been carried out on the young shoots of this plant. In the light of this, the aim of this study was to identify for the first time the flavonoids present in young hop shoots and to compare the composition of samples harvested from different locations in Northern Italy with their antioxidant activity. The samples were extracted by means of dynamic maceration with methanol...
April 29, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28475935/a-comparative-study-on-the-radioprotective-potential-of-the-polyphenolic-glycoconjugates-from-medicinal-plants-of-rosaceae-and-asteraceae-families-versus-their-aglycones
#7
Magdalena Szejk, Tomasz Poplawski, Anna Czubatka-Bienkowska, Alicja Klaudia Olejnik, Izabela Pawlaczyk-Graja, Roman Gancarz, Halina Malgorzata Zbikowska
Radioprotective potential of the polyphenolic glycoconjugates, isolated from flowers of Sanguisorba officinalis L. (So) and Erigeron canadensis L. (Ec), and from leaves of Fragaria vesca L. (Fv) and Rubus plicatus Whe. Et N. E. (Rp) as well as their aglycones (SoA, EcA, FvA and RpA, respectively), against γ-radiation-induced lipid peroxidation in human plasma and DNA damage in lymphocytes, were investigated in vitro. These properties were assessed by measuring the concentration of thiobarbituric acid reactive substances (TBARS) and using the alkaline comet assay, and were compared to the protective effects of rutin (R) and quercetin (Q)...
April 26, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28460970/3-4-dihydroxyphenylacetic-acid-is-a-predominant-biologically-active-catabolite-of-quercetin-glycosides
#8
Yue Tang, Sayaka Nakashima, Shunya Saiki, Yui Myoi, Naomi Abe, Shoko Kuwazuru, Beiwei Zhu, Hitoshi Ashida, Yoshiyuki Murata, Yoshimasa Nakamura
Since dietary flavonoid glycosides, including quercetin 4'-glucoside from onion, are poorly absorbed from the gastrointestinal tract, they are converted into smaller phenolic acids, which can be absorbed into the circulation. The purpose of this study was to compare the effects of the major phenolic acid catabolites of quercetin 4'-glucoside, including 3,4-dihydroxyphenylacetic acid (DOPAC), 3-hydroxyphenylacetic acid, 3,4-dihydroxybenzoic acid (protocatechuic acid) and hippuric acid, on the antioxidant activity and phase II cytoprotective enzyme induction in vitro...
November 2016: Food Research International
https://www.readbyqxmd.com/read/28433637/inhibition-of-pro-inflammatory-enzymes-by-medicinal-plants-from-the-argentinean-highlands-puna
#9
Romina Torres-Carro, María Inés Isla, Samanta Thomas-Valdes, Felipe Jiménez-Aspee, Guillermo Schmeda-Hirschmann, María Rosa Alberto
ETHNOPHARMACOLOGICAL RELEVANCE: Human groups in the Argentinean Andes highlands (Puna) selected native plants as anti-inflammatory agents. The indications of use are mainly to relieve pain, in infusions, ethanolic extracts or plasters. AIM OF THE STUDY: The objective of the study was to assess the effect of hydroalcoholic extracts from native highland plants as anti-inflammatory according to the traditional indications of use. The chemical profile of the three most active species was analyzed by HPLC-ESI-MS to get in insight into the constituents and the effects observed, according to the ethnopharmacological information...
April 19, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28431473/structures-and-bioactivities-of-seven-flavonoids-from-osmanthus-fragrans-jinqiu-essential-oil-extraction-residues
#10
Jiang-Lian Zhou, Xian-Ying Fang, Jing-Qiu Wang, Lin-Guo Zhao, Yi Li, Feng Tang, Yong-De Yue
Osmanthus fragrans are well-known for their fragrance, but it is wasteful if to discard O. fragrans flower after extracting their essential oils. In this paper, we found that O. fragrans flower residues were rich in flavonoids. Six flavonoids and one phenylethanoid glycoside were isolated from the ethanol extract of O. fragrans flower residues, identified as quercetin (1), rutin (2), verbascoside (3), genistin (4), kaempferol (5), isorhamnetin (6) and naringin (7). In bioactivity study, kaempferol (IC50 = 1...
April 21, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28412883/polyphenols-of-virgin-coconut-oil-prevent-pro-oxidant-mediated-cell-death
#11
Soorya Parathodi Illam, Arunaksharan Narayanankutty, Achuthan C Raghavamenon
Virgin coconut oil (VCO), extracted from the fresh coconut kernel, is a food supplement enriched with medium chain saturated fatty acids and polyphenolic antioxidants. It is reported to have several health benefits including lipid lowering, antioxidant and anti-inflammatory activities. The pharmacological benefits of VCO have been attributed to its polyphenol content (VCOP), the mechanistic basis of which is less explored. Liquid chromatography/mass spectroscopy (LC/MS) analysis of VCOP documented the presence of gallic acid, ferulic acid (FA), quercetin, methyl catechin, dihydrokaempferol and myricetin glycoside...
April 26, 2017: Toxicology Mechanisms and Methods
https://www.readbyqxmd.com/read/28407916/protective-property-of-mulberry-digest-against-oxidative-stress-a-potential-approach-to-ameliorate-dietary-acrylamide-induced-cytotoxicity
#12
Linxia Zhang, Yang Xu, Yuting Li, Tao Bao, Vemana Gowd, Wei Chen
The aim of this study was investigating the protective effect of mulberry digest (MBD) on acrylamide-induced oxidative stress. Composition analysis of MBD revealed that it contained six major phenolic compounds (quercetin-3-O-rutinoside, quercetin hexoside, quercetin rhamnosylhexoside hexoside, kaempferol rhamnosylhexoside, cyanidin-3-O-glucoside and cyanidin-3-O-rutinoside). After in vitro digestion, the contents of two anthocyanins were both decreased significantly, while the contents of four flavonoid glycosides were all increased...
September 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28388787/antidiabetic-activities-of-an-lc-ms-fingerprinted-aqueous-extract-of-fagonia-cretica-l-in-preclinical-models
#13
Imran Nazir, Nisar Ur Rahman, Zunaira Alvi, M Hafizur Rahman, Jandirk Sendker, Tao Zhang, Neil Frankish, Helen Sheridan
Diabetes mellitus is a chronic disease and one of the most important public health challenges facing mankind. Fagonia cretica is a medicinal plant used widely in the Punjab in Pakistan. A recent survey has demonstrated that traditional healers and herbalists frequently use this plant to treat diabetes. In the current study, the traditional medicine was prepared as a tea, and the profile of the main metabolites present in the traditional medicine was analysed via LC/MS/MS. The extract was shown to contain a number of phenolic glycosides including quercetin-3-O-rutinoside, kaempferol-3-O-rutinoside, kaempferol-3-O-glycoside, kaempferol-3(6'-malonylglucoside), isorhamnetin-3-O-rutinoside, and isorhamnetin 3-(6″-malonylglucoside) in addition to two unidentified sulphonated saponins...
April 7, 2017: Planta Medica
https://www.readbyqxmd.com/read/28373417/structure-activity-relationships-of-methylquercetin-on-anti-migration-and-anti-proliferation-activity-in-b16-melanoma-cells
#14
Kosei Yamauchi, Tohru Mitsunaga, Syeda H Afroze, Mohammad N Uddin
BACKGROUND: Melanoma is a malignant skin tumor and quercetin has been reported to inhibit metastasis. A quercetin glycoside and 7 methylquercetins were synthesized from rutin to investigate structure-activity relationships. MATERIALS AND METHODS: We evaluated the anti-proliferative and anti-migration activity of quercetin glycoside and 7 methylquercetins in murine B16 melanoma cells by commercially available kits. We also examined the effect of these compounds on growth of human fibroblast cells to evaluate cytotoxicity...
April 2017: Anticancer Research
https://www.readbyqxmd.com/read/28357634/bioactive-flavonoids-from-flos-sophorae
#15
Wenzhong Shi, Lili Liu, Jian Li, Lu Qu, Xu Pang, Haiyang Yu, Yi Zhang, Tao Wang
Three new flavonoid glycosides-soyaflavonosides A (1), B (2), and C (3)-together with 23 known ones were obtained from the 70% EtOH extract of Flos Sophorae (Sophora japonica, Leguminosae). Their structures were elucidated by chemical and spectroscopic methods. Among the known isolates, 14, 18, 20, 22, and 26 were isolated from the Sophora genus for the first time; 12, 19, 24, and 25 were obtained from the species firstly. Moreover, NMR data for compounds 18 and 26 are reported for the first time here. Meanwhile, compounds 4, 8-13, 15, 16, 19, 21, and 22 presented obvious inhibitory effects on TG accumulation in HepG2 cells...
March 29, 2017: Journal of Natural Medicines
https://www.readbyqxmd.com/read/28332768/separation-of-caffeoylquinic-acids-and-flavonoids-from-asteris-souliei-by-high-performance-counter-current-chromatography-and-their-anti-inflammatory-activity-in-vitro
#16
Qiang Zhang, He-Ying Pei, Kai Chen, Huan Tang, Bo Wu, Ming-Hai Tang, Ai-Hua Peng, Hao-Yu Ye, Li-Juan Chen
Eleven compounds were successfully separated from Asteris souliei by using a two-step high-performance counter-current chromatography method. The first step involved a reversed phase isocratic counter-current chromatography separation using hexane/ethyl acetate/methanol/water (1:0.8:1:1 v/v/v/v), which produced three fractions, the first two of which were mixtures. The second step used step-gradient reversed-phase counter-current chromatography with hexane/butanol/ethyl acetate/methanol/water (1:0.5:3.5:1:4 v/v/v/v/v) initially followed by hexane/ethyl acetate/methanol/water (1:2:1:2 v/v/v/v) to separate Fraction 1 into seven compounds; and hexane/ethyl acetate/methanol/water (1:1:1:1...
March 23, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28320327/metabolomics-analysis-reveals-the-metabolic-and-functional-roles-of-flavonoids-in-light-sensitive-tea-leaves
#17
Qunfeng Zhang, Meiya Liu, Jianyun Ruan
BACKGROUND: As the predominant secondary metabolic pathway in tea plants, flavonoid biosynthesis increases with increasing temperature and illumination. However, the concentration of most flavonoids decreases greatly in light-sensitive tea leaves when they are exposed to light, which further improves tea quality. To reveal the metabolism and potential functions of flavonoids in tea leaves, a natural light-sensitive tea mutant (Huangjinya) cultivated under different light conditions was subjected to metabolomics analysis...
March 20, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/28317733/antioxidant-activities-and-structural-characterization-of-flavonol-o-glycosides-from-seeds-of-japanese-horse-chestnut-aesculus-turbinata-blume
#18
Hideto Kimura, Satoshi Ogawa, Tomoe Ishihara, Mahoko Maruoka, Shota Tokuyama-Nakai, Mitsuo Jisaka, Kazushige Yokota
We attempted to evaluate the contents and distribution of antioxidants in the whole seeds, seed shells, and peeled seeds of the Japanese horse chestnut. The seed shells exhibited the highest antioxidant activities due to the presence of highly polymeric proanthocyanidins as we have reported recently. On the other hand, the peeled seeds predominantly contained flavonols such as quercetin and kaempferol at a high level of 66.7% of total polyphenols, also contributing to the predominant antioxidant activities...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28294257/protein-bound-vaccinium-fruit-polyphenols-decrease-ige-binding-to-peanut-allergens-and-rbl-2h3-mast-cell-degranulation-in-vitro
#19
Nathalie J Plundrich, Rishipal R Bansode, E Allen Foegeding, Leonard L Williams, Mary Ann Lila
Peanut allergy is a worldwide health concern. In this study, the natural binding properties of plant-derived polyphenols to proteins was leveraged to produce stable protein-polyphenol complexes comprised of peanut proteins and cranberry (Vaccinium macrocarpon Ait.) or lowbush blueberry (Vaccinium angustifolium Ait.) pomace polyphenols. Protein-bound and free polyphenols were characterized and quantified by multistep extraction of polyphenols from protein-polyphenol complexes. Immunoblotting was performed with peanut-allergic plasma to determine peanut protein-specific IgE binding to unmodified peanut protein, or to peanut protein-polyphenol complexes...
April 19, 2017: Food & Function
https://www.readbyqxmd.com/read/28278644/phytochemical-components-and-biological-activities-of-silene-arenarioides-desf
#20
Lynda Golea, Mohammed Benkhaled, Catherine Lavaud, Christophe Long, Hamada Haba
In this study, six known compounds 1-6 were isolated from the aerial parts of Silene arenarioides Desf. using different chromatographic methods. The structures of these compounds were identified as maltol glycoside (1), soyacerebroside I (2), chrysin (3), apigenin (4), quercetin (5) and stigmasterol glucoside (6). The compounds (1) and (2) are reported for the first time from this genus. The isolated compounds were determined using NMR techniques ((1)H NMR, (13)C NMR, COSY, HSQC and HMBC) and mass spectroscopy (ESI-MS)...
February 24, 2017: Natural Product Research
keyword
keyword
19231
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"