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Creatine supplementation

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https://www.readbyqxmd.com/read/29770871/the-effects-of-acute-leucine-or-leucine-glutamine-co-ingestion-on-recovery-from-eccentrically-biased-exercise
#1
Mark Waldron, Cameron Ralph, Owen Jeffries, Jamie Tallent, Nicola Theis, Stephen David Patterson
This study investigated the effects of leucine or leucine + glutamine supplementation on recovery from eccentric exercise. In a double-blind independent groups design, 23 men were randomly assigned to a leucine (0.087 g/kg; n = 8), leucine + glutamine (0.087 g/kg + glutamine 0.3 g/kg; n = 8) or placebo (0.3 g/kg maltodextrin; n = 7) group. Participants performed 5 sets of drop jumps, with each set comprising 20 repetitions. Isometric knee-extensor strength, counter-movement jump (CMJ) height, delayed-onset muscle soreness (DOMS) and creatine kinase (CK) were measured at baseline, 1, 24, 48 h and 72 h post-exercise...
May 16, 2018: Amino Acids
https://www.readbyqxmd.com/read/29769829/creatine-supplementation-supports-the-rehabilitation-of-adolescent-fin-swimmers-in-tendon-overuse-injury-cases
#2
Imre Juhasz, Judit Plachy Kopkane, Pal Hajdu, Gabor Szalay, Bence Kopper, Jozsef Tihanyi
Our purpose was to investigate the effect of creatine (Cr) supplementation on regeneration periods in tendon overuse injury rehabilitation of adolescent fin swimmers. The participants of this study were injured adolescent competitive fin swimmers (n = 18). The subjects were randomly assigned the creatine (CR) or placebo (PL) groups with a double-blind research design. The subjects were given Cr supplementation or received the placebo as part of the conservative treatment of the tendinopathy. We measured the segmental lean mass (SLM;kg), the ankle plantar flexion peak torque (PFT;N·m), the pain intensity (NRS;values), prior to immobilization, after immobilization (R2) and after the 2nd (R4) and 4th (R6) weeks of the rehabilitation period of the injured limb...
June 2018: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29757945/effectiveness-and-safety-of-dietetic-supplementation-of-a-new-nutraceutical-on-lipid-profile-and-serum-inflammation-biomarkers-in-hypercholesterolemic-patients
#3
Graziano Riccioni, Maria Alessandra Gammone, Walter Currenti, Nicolantonio D'Orazio
Background : To assess the effectiveness and safety of a new nutraceutical (NC) on lipid profile, inflammation biomarkers and creatine phosphokinase (CPK) serum levels in hypercholesterolemic patients. Methods : 40 patients underwent hypolipemic treatment with NC. Initial and final (after 12 weeks) screening included medical history, physical examination, and measurement of serum lipid profile (total cholesterol, HDL-cholesterol, LDL-cholesterol, and triglycerides), hepatic (GOT, GPT, γGT), and renal (serum creatinine and urea) functions, CPK level and many inflammation biomarkers (hs-CRP and fibrinogen)...
May 14, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29756995/guanidinoacetic-acid-supplementation-in-broiler-chickens-fed-corn-soybean-diets-affects-performance-in-the-finisher-period-and-energy-metabolites-in-breast-muscle-independent-of-diet-nutrient-density
#4
Maryam Majdeddin, Abolghasem Golian, Hassan Kermanshahi, Stefaan De Smet, Joris Michiels
Guanidinoacetic acid (GAA) is the single immediate endogenous precursor of creatine. It was hypothesised that dietary GAA would have different effects on performance and energy metabolites in breast muscle depending on the nutrient density (ND) of corn-soybean based diets. A total of 540 one-day-old male Ross 308 broilers were allocated to nine dietary treatments with six replicates (10 birds each) in a 3 × 3 factorial arrangement with three levels of ND (low, 2800; medium, 2950 and high, 3100 kcal ME/kg; and with the other nutrients being constant relative to ME) and supplemented with three levels of GAA (0, 0...
May 14, 2018: British Poultry Science
https://www.readbyqxmd.com/read/29743825/creatine-electrolyte-supplementation-improves-repeated-sprint-cycling-performance-a-double-blind-randomized-control-study
#5
Daniel L Crisafulli, Harsh H Buddhadev, Lorrie R Brilla, Gordon R Chalmers, David N Suprak, Jun G San Juan
Background: Creatine supplementation is recommended as an ergogenic aid to improve repeated sprint cycling performance. Furthermore, creatine uptake is increased in the presence of electrolytes. Prior research examining the effect of a creatine-electrolyte (CE) supplement on repeated sprint cycling performance, however, did not show post-supplementation improvement. The purpose of this double blind randomized control study was to investigate the effect of a six-week CE supplementation intervention on overall and repeated peak and mean power output during repeated cycling sprints with recovery periods of 2 min between sprints...
2018: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29741632/effects-of-guanidinoacetic-acid-on-growth-performance-creatine-and-energy-metabolism-and-carcass-characteristics-in-growing-finishing-pigs
#6
D T He, X R Gai, L B Yang, J T Li, W Q Lai, X L Sun, L Y Zhang
The aim of this study was to investigate the effects of dietary supplementation with guanidinoacetic acid (GAA) on the growth performance, creatine and energy metabolism, and carcass characteristics in growing-finishing pigs. In Exp. 1, Duroc × Landrace × Yorkshire pigs (n = 180, 33.61 ± 3.91 kg average BW) were blocked by weight and sex, and allotted to five treatments with six replicates (3 gilts and 3 barrows per replicate pen). Diets were corn-soybean meal basal diets supplemented with 0, 300, 600, 900, and 1,200 mg/kg of GAA and fed to the pigs for 98 d...
May 7, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29740583/creatine-supplementation-during-resistance-training-does-not-lead-to-greater-bone-mineral-density-in-older-humans-a-brief-meta-analysis
#7
REVIEW
Scott C Forbes, Philip D Chilibeck, Darren G Candow
Creatine supplementation during resistance training has potential beneficial effects on properties of bone in aging adults. We systematically reviewed randomized controlled trials (RCTs) investigating the effect of creatine supplementation combined with resistance training on bone mineral density (BMD) in aging adults. We searched PubMed and SPORTDiscus databases and included RCTs of ≥3 months duration that examined the combined effect of creatine and resistance training on bone mineral in adults >50 years of age or postmenopausal...
2018: Frontiers in Nutrition
https://www.readbyqxmd.com/read/29725246/dehydroepiandrosterone-supplementation-combined-with-weight-loading-whole-body-vibration-training-wwbv-affects-exercise-performance-and-muscle-glycogen-storage-in-middle-aged-c57bl-6-mice
#8
Yi-Ming Chen, Hao-Chieh Lee, Mu-Tsung Chen, Chi-Chang Huang, Wen-Chyuan Chen
Background : Adequate nutritional intake and an optimal training program are important elements of any strategy to preserve or increase muscle mass and strength during aging. Purpose : In the current study, we investigate the effects of Dehydroepiandrosterone (DHEA), one of the most abundant circulating steroids in humans and a precursor hormone, supplementation combined with a weight-loading whole-body vibration (WWBV) on exercise performance, physical fatigue-related biochemical responses and testosterone content in middle-aged 9 months old C57BL/6 mice...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29722252/creatine-monohydrate-supplementation-during-eight-weeks-of-progressive-resistance-training-increases-strength-in-as-little-as-two-weeks-without-reducing-markers-of-muscle-damage
#9
Mojtaba Kaviani, Aboozar Abassi, Philip D Chilibeck
BACKGROUND: Creatine supplementation (Cr) increases strength during resistance training, but the time course of this strength increase is unclear. The aim was to determine the precise time course by which Cr could increase strength and whether Cr prevents muscle damage during eight weeks of resistance training. METHODS: Young males were randomized (double blind) to Cr (n=9, 0.07g/kg/d) and placebo (n=9) during 8-weeks of resistance training (3d/week). Strength was assessed across six exercises every two weeks...
May 2, 2018: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29710855/myoprotective-potential-of-creatine-is-greater-than-whey-protein-after-chemically-induced-damage-in-rat-skeletal-muscle
#10
Matthew B Cooke, Emma Rybalka, Christos G Stathis, Alan Hayes
The myoprotective effects of creatine monohydrate (CR) and whey protein (WP) are equivocal, with the use of proxy measures of muscle damage making interpretation of their effectiveness limited. The purpose of the study was to determine the effects of CR and WP supplementation on muscle damage and recovery following controlled, chemically-induced muscle damage. Degeneration of the extensor digitorum longus (EDL) muscle was induced by bupivacaine in rats supplemented with either CR, WP, or standard rat chow (CON)...
April 30, 2018: Nutrients
https://www.readbyqxmd.com/read/29710025/-a-survivor-of-hodgkin-lymphoma-manifesting-dropped-head-syndrome-as-a-late-onset-complication-of-radiotherapy-a-case-report
#11
Misako Kaido, Yoshihito Yuasa, Hiroshi Ikeda
We report the case of a 50-year-old female survivor of Hodgkin lymphoma (HL), who developed dropped head syndrome (DHS). The patient was diagnosed with HL at 20 years of age, and underwent chemo-radiotherapy, which led to complete remission. Undergoing supplemental therapy for post-radiation hypothyroidism, she had twin babies. She noticed white stains on her neck at the age of 30, and the decolored area gradually expanded. Sixteen years after the radiotherapy (RT), her posterior neck muscle strength began to decline...
April 28, 2018: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29704637/effects-of-creatine-supplementation-on-cognitive-function-of-healthy-individuals-a-systematic-review-of-randomized-controlled-trials
#12
REVIEW
Konstantinos I Avgerinos, Nikolaos Spyrou, Konstantinos I Bougioukas, Dimitrios Kapogiannis
BACKGROUND AND AIMS: Creatine is a supplement used by sportsmen to increase athletic performance by improving energy supply to muscle tissues. It is also an essential brain compound and some hypothesize that it aids cognition by improving energy supply and neuroprotection. The aim of this systematic review is to investigate the effects of oral creatine administration on cognitive function in healthy individuals. METHODS: A search of multiple electronic databases was performed for the identification of randomized clinical trials (RCTs) examining the cognitive effects of oral creatine supplementation in healthy individuals...
April 25, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29698111/arachidonic-acid-supplementation-transiently-augments-the-acute-inflammatory-response-to-resistance-exercise-in-trained-men
#13
James F Markworth, Randall F D'Souza, Kirsten M M Aasen, Sarah M Mitchell, Brenan R Durainayagam, Andrew J Sinclair, Jonathan M Peake, Ingrid Marie Egner, Truls Raastad, David Cameron-Smith, Cameron J Mitchell
Strenuous exercise can result in skeletal muscle damage, leading to the systemic mobilization, activation and intramuscular accumulation of blood leukocytes. Eicosanoid metabolites of arachidonic acid (ARA) are potent inflammatory mediators, but whether changes in dietary ARA intake influence exercise-induced inflammation is not known. This study investigated the effect of 4 weeks of dietary supplementation with 1.5 g/day ARA (n=9, 24 {plus minus} 1.5 years) or corn-soy oil placebo (n=10, 26 {plus minus} 1...
April 26, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29679284/garlic-allium-sativum-exhibits-a-cardioprotective-effect-in-experimental-chronic-renal-failure-rat-model-by-reducing-oxidative-stress-and-controlling-cardiac-na-k-atpase-activity-and-ca-2-levels
#14
Asmaa M S Gomaa, Alaa T Abdelhafez, Hazem A Aamer
Gentamicin (GNT)-induced nephrotoxicity culminates into renal failure with a possible cardiovascular impact. Garlic extract (GE) is a cardiovascular protectant with limited mechanistic data. Therefore, we assessed the disturbance in specific cardiac parameters and the potential protective effect of GE supplementation against them in a rat model of GNT-induced chronic renal failure (CRF). Adult male rats (n = 24) were randomly assigned into four groups (n = 6 each): normal controls (CON), garlic extract controls (GE; 250 mg kg-1 , orally), GNT-induced CRF (GNT; 100 mg kg-1 , i...
April 21, 2018: Cell Stress & Chaperones
https://www.readbyqxmd.com/read/29676656/the-effects-of-beta-hydroxy-beta-methylbutyrate-supplementation-on-recovery-following-exercise-induced-muscle-damage-a-systematic-review-and-meta-analysis
#15
Mohammad Hossein Rahimi, Hamed Mohammadi, Hesam Eshaghi, Gholamreza Askari, Maryam Miraghajani
BACKGROUND: Growing evidence suggests beta-hydroxy-beta-methylbutyrate's (HMB) positive effects on recovery following exercise-induced muscle damage (EIMD). However, findings vary substantially across studies. OBJECTIVE: A meta-analysis of randomized controlled trials was conducted to assess the effects of HMB supplementation on recovery following EIMD by assessing indirect markers of muscle damage, namely creatine kinase (CK) and lactate dehydrogenase (LDH) serum levels among healthy participants...
April 20, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29673544/no-effect-of-creatine-monohydrate-supplementation-on-inflammatory-and-cartilage-degradation-biomarkers-in-individuals-with-knee-osteoarthritis
#16
Stephen M Cornish, Jason D Peeler
The study purpose was to evaluate the effectiveness of creatine monohydrate supplementation (20 grams/day for 1 week and then 5 grams/day for 11 weeks) on inflammation (C-reactive protein, interleukin-1β, interleukin-6, s100 A8/A9, and tumor necrosis factor-α) and cartilage degradation (serum cartilage oligomeric matrix protein) in patients with knee osteoarthritis. We hypothesized that supplementing with creatine monohydrate for 12 weeks would lower biomarkers of inflammation and cartilage degradation in patients with knee osteoarthritis when compared to placebo...
March 2018: Nutrition Research
https://www.readbyqxmd.com/read/29669035/effect-of-guanidinoacetic-acid-supplementation-on-live-performance-meat-quality-pectoral-myopathies-and-blood-parameters-of-male-broilers-fed-corn-based-diets-with-or-without-poultry-by-products
#17
H A Córdova-Noboa, E O Oviedo-Rondón, A H Sarsour, J Barnes, D Sapcota, D López, L Gross, M Rademacher-Heilshorn, U Braun
Creatine is a nitrogenous compound naturally occurring in animal tissues and is obtained from dietary animal protein or de novo synthesis from guanidinoacetic acid (GAA). The dietary supply of this semi-essential nutrient could be adversely compromised when feeding purely vegetable-based diets. The objective of this experiment was to evaluate the effects of GAA supplementation in broilers fed corn-based diets with or without the inclusion of poultry by-products (PBP) on live performance, carcass and cut up yields, meat quality, pectoral muscle myopathies, differential blood count, blood clinical chemistry, serum GAA and its metabolites...
April 13, 2018: Poultry Science
https://www.readbyqxmd.com/read/29659539/post-game-high-protein-intake-may-improve-recovery-of-football-specific-performance-during-a-congested-game-fixture-results-from-the-pro-football-study
#18
Athanasios Poulios, Ioannis G Fatouros, Magni Mohr, Dimitrios K Draganidis, Chariklia Deli, Konstantinos Papanikolaou, Apostolos Sovatzidis, Theofano Nakopoulou, Georgios Ermidis, Theofanis Tzatzakis, Vasiliki C Laschou, Kalliopi Georgakouli, Agisilaos Koulouris, Panagiotis Tsimeas, Athanasios Chatzinikolaou, Leonidas G Karagounis, Dimitrios Batsilas, Peter Krustrup, Athanasios Z Jamurtas
The effects of protein supplementation on performance recovery and inflammatory responses during a simulated one-week in-season microcycle with two games (G1, G2) performed three days apart were examined. Twenty football players participated in two trials, receiving either milk protein concentrate (1.15 and 0.26 g/kg on game and training days, respectively) (PRO) or an energy-matched placebo (1.37 and 0.31 g/kg of carbohydrate on game and training days, respectively) (PLA) according to a randomized, repeated-measures, crossover, double-blind design...
April 16, 2018: Nutrients
https://www.readbyqxmd.com/read/29621580/use-of-nutritional-supplements-contaminated-with-banned-doping-substances-by-recreational-adolescent-athletes-in-athens-greece
#19
Konstantinos Tsarouhas, Nassia Kioukia-Fougia, Petros Papalexis, Aristidis Tsatsakis, Dimitrios Kouretas, Flora Bacopoulou, Christina Tsitsimpikou
Although the use of nutritional supplements by adult athletes has been extensively studied, information on supplements consumption by adolescent athletes is still limited. The present study reports on the use of nutritional supplements contaminated with banned doping substances among 170 recreational adolescent athletes from eleven, randomly selected, gym centres, in Athens, Greece. Nutritional supplements consumption was reported by almost 60% of the study population, with proteins/amino acids and vitamins being the most popular...
April 2, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29617899/in-ovo-applications-in-poultry-a-review
#20
E D Peebles
The various methods employed for the in ovo administration of different materials for promoting the health and productivity of poultry are discussed in this review article. The amnion has proven to be an effective site for injection and the timing of in ovo injection has commonly occurred at transfer. However, the volumes and dosages or concentrations of the materials administered vary depending on bird type, egg size, timing and site of injection, incubation system and regimen, and the type of material. Both manual and automated injections have been shown to be effective...
March 28, 2018: Poultry Science
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