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Ultrasound ovarian tumour

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https://www.readbyqxmd.com/read/29156299/outcomes-from-ovarian-cancer-screening-in-the-plco-trial-histologic-heterogeneity-impacts-detection-overdiagnosis-and-survival
#1
Sarah M Temkin, Eric A Miller, Goli Samimi, Christine D Berg, Paul Pinsky, Lori Minasian
AIM: A mortality benefit from screening for ovarian cancer has never been demonstrated. The aim of this study was to evaluate the screening outcomes for different histologic subtypes of ovarian cancers. METHODS: Women in the screening arm of the Prostate, Lung, Colorectal and Ovarian Screening Trial underwent CA-125 and transvaginal ultrasound annually for 3-5 years. We compared screening test characteristics (including overdiagnosis) and outcomes by tumour type (type II versus other) and study arm (screening versus usual care)...
November 16, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/29131023/evaluation-of-serum-nidogen-2-as-a-screening-and-diagnostic-tool-for-ovarian-cancer
#2
Haitham A Torky, Ahmed Sherif, Ashraf Abo-Louz, Mohamed Ali, Ali Ahmed, Ahmad Ali
INTRODUCTION: Ovarian cancer is a relatively common occurrence with the formation of a tumour in the ovaries and is the leading cause of death in the gynecological field. Despite enormous efforts, there are no successful screening methods developed until now to decrease mortality in this regard. AIM: To evaluate nidogen-2 as a new tumour marker combined with higher sensitivity, specificity and accuracy than carbohydrate antigen (CA-125) and Doppler ultrasound to improve early diagnosis of ovarian cancer...
November 7, 2017: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/28976616/a-prospective-evaluation-of-the-iota-logistic-regression-models-lr1-and-lr2-in-comparison-to-subjective-pattern-recognition-for-the-diagnosis-of-ovarian-cancer-in-the-outpatient-setting
#3
Natalie Nunes, Gareth Ambler, Xulin Foo, Martin Widschwendter, Davor Jurkovic
OBJECTIVES: To determine whether IOTA diagnostic models developed for pre-operative diagnosis of ovarian cancer could also be used to differentiate between benign and malignant adnexal tumours in the population of women attending gynaecology outpatient clinics. METHODS: All women referred to our outpatient clinic were first examined by a Level II ultrasound operator. In those diagnosed with adnexal tumours the IOTA LR1/2 protocol was used to evaluate the masses...
October 4, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28969237/evaluation-of-iota-simple-ultrasound-rules-to-distinguish-benign-and-malignant-ovarian-tumours
#4
Sugandha Garg, Amarjit Kaur, Jaswinder Kaur Mohi, Preet Kanwal Sibia, Navkiran Kaur
INTRODUCTION: IOTA stands for International Ovarian Tumour Analysis group. Ovarian cancer is one of the common cancers in women and is diagnosed at later stage in majority. The limiting factor for early diagnosis is lack of standardized terms and procedures in gynaecological sonography. Introduction of IOTA rules has provided some consistency in defining morphological features of ovarian masses through a standardized examination technique. AIM: To evaluate the efficacy of IOTA simple ultrasound rules in distinguishing benign and malignant ovarian tumours and establishing their use as a tool in early diagnosis of ovarian malignancy...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28837575/development-of-a-tool-for-prediction-of-ovarian-cancer-in-patients-with-adnexal-masses-value-of-plasma-fibrinogen
#5
Veronika Seebacher, Stefanie Aust, David D'Andrea, Christoph Grimm, Elisabeth Reiser, Denise Tiringer, Hannah Von Mersi, Stephan Polterauer, Alexander Reinthaller, Samir Helmy-Bader
OBJECTIVE: To develop a tool for individualized risk estimation of presence of cancer in women with adnexal masses, and to assess the added value of plasma fibrinogen. STUDY DESIGN: We performed a retrospective analysis of a prospectively maintained database of 906 patients with adnexal masses who underwent cystectomy or oophorectomy. Uni- and multivariate logistic regression analyses including pre-operative plasma fibrinogen levels and established predictors were performed...
2017: PloS One
https://www.readbyqxmd.com/read/28763365/ultrasound-guided-laparoscopic-ovarian-wedge-resection-in-recurrent-serous-borderline-ovarian-tumours
#6
Benjamin P Jones, Srdjan Saso, Jessica Farren, Mona El-Bahrawy, Sadaf Ghaem-Maghami, J Richard Smith, Joseph Yazbek
OBJECTIVE: The aim of this study was to demonstrate the use of intraoperative ultrasound-guided ovarian wedge resection in the treatment of recurrent serous borderline ovarian tumors (sBOTs) that are too small to be visualized laparoscopically. METHODS: This was a prospective analysis of all women with recurrent sBOTs that were not visible laparoscopically, who underwent intraoperative ultrasound-guided ovarian wedge resection between January 2015 and December 2016 at the West London Gynaecological Cancer Centre, Imperial College NHS Trust, London, United Kingdom...
November 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28712200/pregnancy-with-bilateral-metastatic-ovarian-tumour
#7
Sadaqat Jabeen, Maleeha Nisar, Nighat Hussain
Metastatic ovarian tumours are extremely rare. The commonest primary site is usually stomach and the metastasis from this site is termed as krukenberg tumour. It accounts for 1-2% of malignant ovarian tumours. We present a case of 14 weeks' pregnancy with metastatic bilateral malignant ovarian tumour is presented. Diagnosis was made on ultrasound. Tumour markers were insignificant. Patient underwent staging laparotomy with total abdominal hysterectomy and bilateral salpingo oophorectomy and partial omentectomy...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28572843/malignant-struma-ovarii-in-a-30-year-old-nulliparous-patient
#8
J Colin Boyd, Blair A Williams, Matthew H Rigby, Katharina Kieser, Saul Offman, Hemlata Shirsat, Jonathan R B Trites, S Mark Taylor, Robert D Hart
BACKGROUND: Struma ovarii is a rare monodermal germ cell tumor where the ovary is comprised of at least half thyroid tissue. This phenomenon may indicate an embryological origin. CASE PRESENTATION: A 30-year old nulliparous woman presented with acute right lower quadrant pain and underwent laparoscopic right salpingo-oophorectomy. The excised ovarian mass showed evidence of struma-derived papillary thyroid carcinoma. Ultrasound of the thyroid showed mild enlargement with two solid nodules...
2017: Thyroid Research
https://www.readbyqxmd.com/read/28152542/comparison-of-two-protocols-for-the-management-of-asymptomatic-postmenopausal-women-with-adnexal-tumours-a-randomised-controlled-trial-of-rmi-rcog-vs-simple-rules
#9
RANDOMIZED CONTROLLED TRIAL
Natalie Nunes, Gareth Ambler, Xulin Foo, Joel Naftalin, Grigoris Derdelis, Martin Widschwendter, Davor Jurkovic
BACKGROUND: Adnexal tumours are frequently diagnosed in asymptomatic postmenopausal women due to more liberal use of modern high-resolution imaging. This study's objective was to determine if there would be a difference in the intervention rates when using the Simple Rules Management Protocol (SRMP) as compared to the Risk of Malignancy Index in the Royal College of Obstetricians and Gynaecologists guideline (RMI/RCOG). METHODS: This was a prospective randomised controlled trial with the participants and the researchers non-blinded, and the surgeons and pathologists blinded...
February 28, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28028390/spectrum-of-childhood-and-adolescent-ovarian-tumors-in-india-25-years-experience-at-a-single-institution
#10
Ruchi Rathore, Sonal Sharma, Deepshikha Arora
BACKGROUND: Ovarian tumour in children and adolescent girls form an uncommon but important part of gynaecological malignancies. They account for 1% of all the childhood malignancies and 8% of all abdominal tumours in children. Since the ovarian cysts are thought to arise from mature follicles, these tumours were considered to be infrequent in the paediatric population. AIM: The rarity of this condition prompted us to conduct this study and share our experience on the incidence and clinicopathological features of different ovarian tumours in girls up to 20 years of age observed in last 25 years at a single tertiary care hospital...
December 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27803082/leydig-cell-tumour-and-mature-ovarian-teratoma-rare-androgen-secreting-ovarian-tumours-in-postmenopausal-women
#11
Ana Palha, Luísa Cortez, Ana Paula Tavares, Ana Agapito
Androgen-secreting ovarian tumours are extremely rare accounting for <5% of all ovarian neoplasms. They are more frequent in postmenopausal women and should be suspected in the case of a rapid onset of androgenic symptoms. We report 4 cases of postmenopausal women who presented with signs of virilisation. All patients revealed increased serum levels of testosterone, normal dehydroepiandrosterone-sulfate and negative pelvic ultrasound for adnexal masses. An androgen-secreting ovarian tumour was suspected and all of them were submitted to bilateral oophorectomy...
November 1, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27511754/rapid-recovery-from-catastrophic-paraneoplastic-anti-nmdar-encephalitis-secondary-to-an-ovarian-teratoma-following-ovarian-cystectomy
#12
Charuwan Tantipalakorn, Atiwat Soontornpun, Tip Pongsuvareeyakul, Theera Tongsong
This report is aimed to describe a life-threatening case of anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis secondary to ovarian teratoma with rapid recovery in 1 day after the removal of the tumour. A 23-year-old woman presented with sudden headache, personality changes and seizure. After neurological assessment, limbic or herpes encephalitis was provisionally diagnosed and treated with intravenous immunoglobulin, acyclovir and steroids. The patient had progressive severe neurological symptoms, requiring prolonged intubation and mechanical ventilation...
August 10, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27507231/refining-ovarian-cancer-test-accuracy-scores-rockets-protocol-for-a-prospective-longitudinal-test-accuracy-study-to-validate-new-risk-scores-in-women-with-symptoms-of-suspected-ovarian-cancer
#13
Sudha Sundar, Caroline Rick, Francis Dowling, Pui Au, Kym Snell, Nirmala Rai, Rita Champaneria, Hilary Stobart, Richard Neal, Clare Davenport, Susan Mallett, Andrew Sutton, Sean Kehoe, Dirk Timmerman, Tom Bourne, Ben Van Calster, Aleksandra Gentry-Maharaj, Usha Menon, Jon Deeks
INTRODUCTION: Ovarian cancer (OC) is associated with non-specific symptoms such as bloating, making accurate diagnosis challenging: only 1 in 3 women with OC presents through primary care referral. National Institute for Health and Care Excellence guidelines recommends sequential testing with CA125 and routine ultrasound in primary care. However, these diagnostic tests have limited sensitivity or specificity. Improving accurate triage in women with vague symptoms is likely to improve mortality by streamlining referral and care pathways...
2016: BMJ Open
https://www.readbyqxmd.com/read/27491160/-ultrasound-criteria-or-the-operability-and-efficacy-of-the-treatment-of-the-malignant-epithelial-ovarian-tumours
#14
K D Shkarbun, L I Shkarbun
In order to isolate the main sonographic criteria of ovarian cancer operability the dynamical U.S. examination was performed on 65 women with epithelial tumors of II-III stages before and during 5 years after treatment beginning, which included (in different combinations) cytoreductive surgery and neoadjuvant chemotherapy. Only total 14 (21.5%) relapses were revealed. The U.S. prognostic criteria of the ovarian cancer treatment efficacy with and without neoadjuvant chemotherapy were defined.
October 2015: Likars'ka Sprava
https://www.readbyqxmd.com/read/27448792/ovarian-dysgerminoma-presenting-as-a-pregnancy-case-report
#15
Solwayo Ngwenya
A 32 year-old P4 G4 was referred from a rural hospital for fibroids in pregnancy. The pregnancy test was positive. An ultrasound scan reported a huge left extrauterine mass. The uterus was of normal size. There was no pregnancy demonstrated. A laparotomy was done through a midline incision. There was a huge left ovarian tumour occupying the pelvic/abdominal region right up to the xiphisternum. A left salpingo-oophrectomy was done. The post operative period was uneventful. The histopathological report confirmed the diagnosis of ovarian dysgerminoma FIGO stage 1A...
January 2017: Tropical Doctor
https://www.readbyqxmd.com/read/27282774/age-related-differences-in-the-sonographic-characteristics-of-endometriomas
#16
Stefano Guerriero, Ben Van Calster, Edgardo Somigliana, Silvia Ajossa, Wouter Froyman, Bavo De Cock, An Coosemans, Daniela Fischerová, Caroline Van Holsbeke, Juan Luis Alcazar, Antonia C Testa, Lil Valentin, Tom Bourne, Dirk Timmerman
STUDY QUESTION: Do sonographic characteristics of ovarian endometriomas vary with age in premenopausal women? SUMMARY ANSWER: With increasing age, multilocular cysts and cysts with papillations and other solid components become more common whereas ground glass echogenicity of cyst fluid becomes less common. WHAT IS KNOWN ALREADY: Expectant or medical management of women with endometriomas is now accepted. Therefore, the accuracy of non-invasive diagnosis of these cysts is pivotal...
August 2016: Human Reproduction
https://www.readbyqxmd.com/read/27225154/sarcoma-like-mural-nodule-in-a-borderline-mucinous-tumour-of-ovary
#17
Rabia Ahmed, Hafeez Ud Din, Shoaib Naiyar Hashmi, Iqbal Muhammad
A 37-year female presented with complaint of lower abdominal pain and amenorrhoea to the Military Hospital, Rawalpindi. Ultrasound of pelvis showed a right adnexal cystic lesion. On investigation, CA-125 was raised. Her MRI scan of pelvis revealed a right adnexal mass of fluid intensity measuring 15.2 x 12.9 x 9.2 cm. Right ovarian cystectomy was performed and the specimen was sent for histopathological examination. Grossly, the mass was cystic in appearance and measured 13.5 x 10 x 10 cm. On sectioning, it was unilocular and filled with turbid material...
May 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/26968295/from-syncope-episode-to-the-diagnosis-of-ovarian-dermoid-cyst-associated-with-a-cystadenoma
#18
Ancuta Augustina Gheorghisan-Galateanu, Mara Carsote, Anda Dumitrascu, Andreea Geleriu, Dana Terzea, Catalina Poiana
Ovarian teratoma has various presentations. We present a 28-year female diagnosed with a tumour after a fainting episode. Medical history was non-contributory except for mild intermittent pelvic pain. Cardiologic and neurological evaluation found no cause of syncope. Abdominal ultrasound revealed a right ovarian tumour that was laparoscopically removed. The menses continued to be normal. The pathological exam showed an encapsulated tumour of 8 cm with hair and small bone parts (mature teratoma with a cystadenoma)...
March 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/26922169/subjective-assessment-versus-ultrasound-models-to-diagnose-ovarian-cancer-a-systematic-review-and-meta-analysis
#19
REVIEW
E M J Meys, J Kaijser, R F P M Kruitwagen, B F M Slangen, B Van Calster, B Aertgeerts, J Y Verbakel, D Timmerman, T Van Gorp
INTRODUCTION: Many national guidelines concerning the management of ovarian cancer currently advocate the risk of malignancy index (RMI) to characterise ovarian pathology. However, other methods, such as subjective assessment, International Ovarian Tumour Analysis (IOTA) simple ultrasound-based rules (simple rules) and IOTA logistic regression model 2 (LR2) seem to be superior to the RMI. Our objective was to compare the diagnostic accuracy of subjective assessment, simple rules, LR2 and RMI for differentiating benign from malignant adnexal masses prior to surgery...
May 2016: European Journal of Cancer
https://www.readbyqxmd.com/read/26691938/-hereditary-breast-and-ovarian-cancer-syndrome
#20
K Petráková, M Palácová, M Schneiderová, M Standara
Population with hereditary breast and ovarian cancer syndrome, i.e. BRCA1/2 mutation carriers, are at higher risk of developing breast and ovarian cancer as well as other solid tumours such as pancreatic cancer, prostate cancer and melanoma. With the increasing experience, screening recommendations and preventive strategies including prophylactic surgery are being settled. Surveillance of women with hereditary breast cancer syndrome comprises clinical breast examination every six months, breast ultrasound and MRI in patients aged 25 to 29 and MRI and mammography in women aged 30 to 65...
2016: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
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