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https://www.readbyqxmd.com/read/28749550/combined-resistance-and-endurance-training-at-a-moderate-high-intensity-improves-physical-condition-and-quality-of-life-in-liver-transplant-patients
#1
Diego Moya-Nájera, Ángel Moya-Herraiz, Luis Compte-Torrero, David Hervás, Sebastien Borreani, Joaquin Calatayud, Marina Berenguer, Juan C Colado
BACKGROUND: Although currently, moderate and high intensity concurrent physical exercise is prescribed in populations with special needs due to its greater effect on physical condition and health-related quality of life (HRQOL), there are no data in the liver transplantation (LT) setting. AIM: To evaluate changes in maximal strength, aerobic capacity, body composition, liver function, and HRQOL in LT patients after a moderate to high intensity combined resistance-endurance training...
July 27, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28749549/a-double-blind-placebo-controlled-study-of-rituximab-in-patients-with-stiff-person-syndrome
#2
Marinos C Dalakas, Goran Rakocevic, James M Dambrosia, Harry Alexopoulos, Beverly McElroy
Objective In Stiff-Person Syndrome (SPS), an antibody-mediated impaired GABAergic neurotransmission is believed to cause muscle stiffness and spasms. Patients improve with GABA-enhancing drugs and IVIg, but several respond poorly and remain disabled. The need for more effective therapy prompted a trial with the anti-CD20 monoclonal antibody rituximab. Methods This was a placebo-controlled randomized trial of rituximab (two bi-weekly infusions of 1gr each). The primary outcome was a change in stiffness scores at 6 months...
July 27, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28749453/mindfulness-based-stress-reduction-therapy-improves-patient-and-caregiver-reported-outcomes-in-cirrhosis
#3
Jasmohan S Bajaj, Michael Ellwood, Timothy Ainger, Thomas Burroughs, Andrew Fagan, Edith A Gavis, Douglas M Heuman, Michael Fuchs, Binu John, James B Wade
OBJECTIVES: Patient-reported outcomes such as health-related quality of life (HRQOL) are impaired in cirrhosis due to under-treated mood and sleep disorders, which can adversely impact their caregivers. Mindfulness-based stress reduction (MBSR) can improve patient-reported outcomes (PRO) in non-cirrhotic patients but their impact in cirrhosis is unclear. To evaluate the effect of MBSR and supportive group therapy on mood, sleep and HRQOL in cirrhotic patients and their caregivers. METHODS: Cirrhotic outpatients with mild depression (Beck Depression Inventory (BDI)>14) on screening with an adult caregiver were enrolled...
July 27, 2017: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/28749315/connecting-medical-records-an-evaluation-of-benefits-and-challenges-for-primary-care-practices
#4
Deborah Ruth Compeau, Amanda Terry
BACKGROUND: Implementation of systems to support health information sharing has lagged other areas of healthcare IT, yet offers a strong possibility for benefit.  Clinical acceptance is a key limiting factor in health IT adoption. OBJECTIVES: To assess the benefits and challenges experienced by clinicians using a custom-developed health information exchange system, and to show how perceptions of benefits and challenges influence perceptions of productivity and care-related outcomes...
June 30, 2017: Journal of Innovation in Health Informatics
https://www.readbyqxmd.com/read/28749185/internalised-hiv-stigma-loneliness-depressive-symptoms-and-sleep-quality-in-people-living-with-hiv
#5
Erin M Fekete, Stacey L Williams, Matthew D Skinta
OBJECTIVE: People living with HIV (PLWH) commonly report sleep disturbances which are associated with long-term health consequences, including disease progression. PLWH also experience internalised stigma as a result of their HIV status, which can be associated with increased loneliness and depression. Little attention focuses on the impact of these factors on sleep. Therefore, we examined whether internalised HIV-stigma was indirectly related to poorer sleep quality through higher levels of loneliness and depressive symptoms...
July 27, 2017: Psychology & Health
https://www.readbyqxmd.com/read/28748994/-intravenous-thrombolysis-for-acute-ischemic-stroke-a-four-years%C3%A2-experience-in-a-chilean-public-hospital
#6
Álvaro Soto V, Gladys Morales I, Marcela Grandjean B, Débora Pollak W, Carolina Del Castillo C, Pía García F, Alexis Von Johnn A, Alfonso Riquelme G
BACKGROUND: Intravenous thrombolysis (IVT) with alteplase (tissue plasminogen activator) is the standard pharmacological treatment in acute ischemic stroke (AIS), reducing disability in patients. AIM: To report the results a thrombolysis protocol during four years in a regional public hospital. MATERIAL AND METHODS: Data from 106 consecutive patients aged 68 ± 13 years (57% men) who were treated with IVT, from May 2012 until April 2016, was analyzed...
April 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28748679/quality-of-anticoagulation-with-warfarin-in-korean-patients-with-atrial-fibrillation-and-prior-stroke-a-multicenter-retrospective-observational-study
#7
Keun Sik Hong, Yang Ki Kim, Hee Joon Bae, Hyo Suk Nam, Sun U Kwon, Oh Young Bang, Jae Kwan Cha, Byung Woo Yoon, Joung Ho Rha, Byung Chul Lee, Jong Moo Park, Man Seok Park, Jun Lee, Jay Chol Choi, Dong Eog Kim, Kyung Bok Lee, Tai Hwan Park, Ji Sung Lee, Seong Eun Kim, Juneyoung Lee
BACKGROUND AND PURPOSE: The quality of anticoagulation is critical for ensuring the benefit of warfarin, but this has been less well studied in Korean ischemic stroke patients with atrial fibrillation (AF). METHODS: This study retrospectively analyzed the data of patients who had an AF-related ischemic stroke and were treated with long-term warfarin therapy in 16 Korean centers. The quality of warfarin therapy was primarily assessed by the time in therapeutic range [TTR; international normalized ratio (INR), 2...
July 2017: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/28748624/the-relationship-between-coping-style-and-psychological-distress-in-people-with-head-and-neck-cancer-a-systematic-review
#8
REVIEW
Nicolle Morris, Nima Moghaddam, Anna Tickle, Sanchia Biswas
OBJECTIVE: Individuals diagnosed with head and neck cancer (HNC) are at an elevated risk of experiencing psychological distress and a reduced quality of life. The aim of this review was to systematically examine and assess the quality of empirical evidence on the associations between coping mechanisms and psychological distress among people with HNC. METHODS: CINAHL, MEDLINE, PsycINFO, EMBASE and Web of Science were accessed to conduct this review. Studies were included if they used reliable and valid measures to investigate the relationship between coping style and psychological distress...
July 27, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28748535/financial-incentives-and-physician-practice-participation-in-medicare-s-value-based-reforms
#9
Adam M Markovitz, Patricia P Ramsay, Stephen M Shortell, Andrew M Ryan
OBJECTIVES: To evaluate whether greater experience and success with performance incentives among physician practices are related to increased participation in Medicare's voluntary value-based payment reforms. DATA SOURCES/STUDY SETTING: Publicly available data from Medicare's Physician Compare (n = 1,278; January 2012 to November 2013) and nationally representative physician practice data from the National Survey of Physician Organizations 3 (NSPO3; n = 907,538; 2013)...
July 26, 2017: Health Services Research
https://www.readbyqxmd.com/read/28748524/the-effects-of-segmentation-algorithms-on-the-measurement-of-18-f-fdg-pet-texture-parameters-in-non-small-cell-lung-cancer
#10
Usman Bashir, Gurdip Azad, Muhammad Musib Siddique, Saana Dhillon, Nikheel Patel, Paul Bassett, David Landau, Vicky Goh, Gary Cook
BACKGROUND: Measures of tumour heterogeneity derived from 18-fluoro-2-deoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) scans are increasingly reported as potential biomarkers of non-small cell lung cancer (NSCLC) for classification and prognostication. Several segmentation algorithms have been used to delineate tumours, but their effects on the reproducibility and predictive and prognostic capability of derived parameters have not been evaluated. The purpose of our study was to retrospectively compare various segmentation algorithms in terms of inter-observer reproducibility and prognostic capability of texture parameters derived from non-small cell lung cancer (NSCLC) (18)F-FDG PET/CT images...
December 2017: EJNMMI Research
https://www.readbyqxmd.com/read/28748476/quantitative-rt-pcr-for-micrornas-in-biofluids
#11
Michael Thorsen, Thorarinn Blondal, Peter Mouritzen
MicroRNAs in biofluids hold great promise as minimally invasive diagnostic biomarkers for a wide range of diseases and biological processes. One of the most sensitive technologies for detection and measuring expression levels of microRNA is quantitative RT-PCR. However, quantification of microRNA in biofluid samples is challenging in many ways. Biofluids contain low levels of RNA and high levels of inhibitors of enzymatic processes like reverse transcription and PCR. Furthermore, biofluids are susceptible to many preanalytical variables...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28748427/measurements-of-stem-diameter-implications-for-individual-and-stand-level-errors
#12
Keryn I Paul, John S Larmour, Stephen H Roxburgh, Jacqueline R England, Micah J Davies, Hamish D Luck
Stem diameter is one of the most common measurements made to assess the growth of woody vegetation, and the commercial and environmental benefits that it provides (e.g. wood or biomass products, carbon sequestration, landscape remediation). Yet inconsistency in its measurement is a continuing source of error in estimates of stand-scale measures such as basal area, biomass, and volume. Here we assessed errors in stem diameter measurement through repeated measurements of individual trees and shrubs of varying size and form (i...
August 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28748378/validation-of-an-egyptian-arabic-version-of-skindex-16-and-quality-of-life-measurement-in-egyptian-patients-with-skin-disease
#13
Nagwa Essa, Sara Awad, Mariam Nashaat
PURPOSE: To translate and cross-culturally adapt the Skindex-16, a brief skin-disease-specific QoL questionnaire, into Arabic for Egyptians and to evaluate its measurement properties in Egyptian patients with skin disease. METHOD: Translation and cultural adaption were performed following guidelines for cross-cultural adaption of health-related quality of life measures. Subsequently, Skindex-16 was administered to 500 consecutive dermatological patients and 500 healthy persons for verification of its reliability and validity...
July 26, 2017: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28748325/the-sense-of-quality-of-life-and-religious-strategies-of-coping-with-stress-in-prison-inmates
#14
Elżbieta Talik, Bartłomiej Skowroński
The aim of the presented research was to analyze differences in religious strategies of coping with stress in a group of prison inmates characterized by different levels of the sense of quality of life-general, psychophysical, psychosocial, personal, and metaphysical. The participants were 390 males, aged 19-68 years, serving sentences in prisons in Poland. The measures used were the Sense of Quality of Life Questionnaire by M. Straś-Romanowska and K. I. Pargament's RCOPE Questionnaire. As expected, individuals with a high sense of quality of life-both general and pertaining to specific dimensions-more often chose positive religious strategies, whereas participants with a low sense of quality of life more often chose negative strategies...
July 26, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28748308/smoking-health-related-quality-of-life-and-economic-evaluation
#15
Ángel López-Nicolás, Marta Trapero-Bertran, Celia Muñoz
BACKGROUND AND AIMS: The economic evaluation of tobacco control policies requires the adoption of assumptions about the impact of changes in smoking status on health-related quality of life (HRQoL). Estimates for such impacts are necessary for different populations. This paper aims to test whether smoking status has an independent effect on HRQoL over and above the effect derived from the increased likelihood of suffering a tobacco related disease, and to calculate utility values for the Spanish population...
July 26, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28748108/readyspeech-for-people-with-dysarthria-after-stroke-protocol-for-a-feasibility-randomised-controlled-trial
#16
Claire Mitchell, Audrey Bowen, Sarah Tyson, Paul Conroy
BACKGROUND: Dysarthria, a disordered speech production resulting from neuro-muscular impairment, is a common symptom after stroke. It causes significant problems for patients' speech intelligibility, communication, psychological well-being, social engagement and stroke recovery. Rehabilitation for dysarthria is variable in quality, intensity and duration, which may be, in part, due to the lack of good quality evidence. An online therapy programme, ReaDySpeech, has the potential to improve quality, intensity and duration of speech rehabilitation and was considered in a proof-of-concept study to be acceptable to speech and language therapists and patients which warranted further evaluation...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28748107/study-protocol-a-mixed-methods-feasibility-study-for-a-loaded-self-managed-exercise-programme-for-patellofemoral-pain
#17
Benjamin E Smith, Paul Hendrick, Marcus Bateman, Fiona Moffatt, Michael Skovdal Rathleff, James Selfe, Toby O Smith, Pip Logan
BACKGROUND: Patellofemoral pain (PFP) is one of the most common forms of knee pain in adults under the age of 40, with a prevalence of 23% in the general population. The long-term prognosis is poor, with only one third of people pain-free 1 year after diagnosis. The biomedical model of pain in relation to persistent PFP has recently been called into question. It has been suggested that interventions for chronic musculoskeletal conditions should consider alternative mechanisms of action, beyond muscles and joints...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28748092/a-focused-ultrasound-treatment-system-for-moving-targets-part-i-generic-system-design-and-in-silico-first-stage-evaluation
#18
Michael Schwenke, Jan Strehlow, Daniel Demedts, Sabrina Haase, Diego Barrios Romero, Sven Rothlübbers, Caroline von Dresky, Stephan Zidowitz, Joachim Georgii, Senay Mihcin, Mario Bezzi, Christine Tanner, Giora Sat, Yoav Levy, Jürgen Jenne, Matthias Günther, Andreas Melzer, Tobias Preusser
BACKGROUND: Focused ultrasound (FUS) is entering clinical routine as a treatment option. Currently, no clinically available FUS treatment system features automated respiratory motion compensation. The required quality standards make developing such a system challenging. METHODS: A novel FUS treatment system with motion compensation is described, developed with the goal of clinical use. The system comprises a clinically available MR device and FUS transducer system...
2017: Journal of Therapeutic Ultrasound
https://www.readbyqxmd.com/read/28748086/area-health-education-center-ahec-programs-for-rural-and-underrepresented-minority-students-in-the-alabama-black-belt
#19
Ashruta Patel, Regina J Knox, Alicia Logan, Katie Summerville
BACKGROUND: This paper evaluated the implementation West Central Alabama Area Health Education Center programs for high school students in grades 9-12 through participant-reported evaluations and feedback during the  September 1st, 2013 to August 31st, 2014 fiscal year. The programs targeted racial/ethnic minorities and/or rural individuals interested in pursuing a career as a healthcare provider in medically underserved counties of Alabama. METHODS: Students participated in enrichment activities related to prospective health careers that included: successful college preparedness, knowledge about health careers, and the types of primary care health professions that are needed in underserved Alabama communities...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28747996/triptorelin-for-the-relief-of-lower-urinary-tract-symptoms-in-men-with-advanced-prostate-cancer-results-of-a-prospective-observational-grouped-analysis-study
#20
Thierry Gil, Fouad Aoun, Patrick Cabri, Valérie Perrot, Roland van Velthoven
BACKGROUND: Lower urinary tract symptoms (LUTSs) may develop in men with prostate cancer (PCa) and can impact quality of life (QoL). Gonadotropin-releasing hormone (GnRH) agonists as androgen deprivation therapy are standard treatment for PCa, however, data are limited on their effects on LUTSs. A grouped analysis of national observational, non-interventional studies initiated in clinical practice was performed to assess the effectiveness of triptorelin in reducing moderate or severe LUTSs, measured using the International Prostate Symptom Score (IPSS) in men with advanced or metastatic PCa...
July 2017: Therapeutic Advances in Urology
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