Lucie Kadrnozkova, Manuela Vaneckova, Lukas Sobisek, Barbora Benova, Karolina Kucerova, Jiri Motyl, Michaela Andelova, Klara Novotna, Jana Lizrova Preiningerova, Jan Krasensky, Eva Havrdova, Dana Horakova, Tomas Uher
BACKGROUND: Multiple sclerosis (MS) is frequently diagnosed in the most productive years of adulthood and is often associated with worsening employment status. However, reliable predictors of employment status change are lacking. OBJECTIVE: To identify early clinical and brain magnetic resonance imaging (MRI) markers of employment status worsening in MS patients at 12-year follow-up. METHODS: A total of 145 patients with early relapsing-remitting MS from the original Avonex-Steroids-Azathioprine (ASA) study were included in this prospective, longitudinal, observational cohort study...
May 15, 2018: Journal of the Neurological Sciences